Damien BREGEON

27
Documents

Publications

Publications

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Beyond RNA modification: a novel role for tRNA modifying enzyme in oxidative stress response and metabolism

Louna Fruchard , Claudia Sudol , Caroline Rouard , Aurore Treffkorn-Maurau , Léo Hardy et al.

Nucleic Acids Research, 2025, 53 (22), pp.gkaf1276. ⟨10.1093/nar/gkaf1276⟩

Article dans une revue pasteur-05438616v1
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Functional redundancy in tRNA dihydrouridylation

Claudia Sudol , Lea-Marie Kilz , V. Marchand , Quentin Thullier , Vincent Guérineau et al.

Nucleic Acids Research, 2024, 52 (10), pp.5880-5894. ⟨10.1093/nar/gkae325⟩

Article dans une revue hal-04614743v1
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Exploring a unique class of flavoenzymes: Identification and biochemical characterization of ribosomal RNA dihydrouridine synthase

Sabrine Toubdji , Quentin Thullier , Lea-Marie Kilz , V. Marchand , Yifeng Yuan et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (32), pp.e2401981121. ⟨10.1073/pnas.2401981121⟩

Article dans une revue hal-04734945v1
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Differential redox sensitivity of tRNA dihydrouridylation

Lea-Marie Kilz , Simone Zimmermann , Virginie Marchand , Valérie Bourguignon , Claudia Sudol et al.

Nucleic Acids Research, 2024, 52 (21), pp.12784-12797. ⟨10.1093/nar/gkae964⟩

Article dans une revue (article de synthèse) hal-04911631v1
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DORQ-seq: high-throughput quantification of femtomol tRNA pools by combination of cDNA hybridization and Deep sequencing

Marco Kristen , Marc Lander , Lea-Marie Kilz , Lukas Gleue , Marko Jörg et al.

Nucleic Acids Research, 2024, 52 (18), pp.e89. ⟨10.1093/nar/gkae765⟩

Article dans une revue hal-05357069v1
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Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family

Murielle Lombard , Colbie J Reed , Ludovic Pecqueur , Bruno Faivre , Sabrine Toubdji et al.

Biomolecules, 2022, 12 (12), pp.1760. ⟨10.3390/biom12121760⟩

Article dans une revue hal-04238858v1
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Dihydrouridine in the transcriptome: New life for this ancient RNA chemical modification

Damien Brégeon , Ludovic Pecqueur , Sabrine Toubdji , Claudia Sudol , Murielle Lombard et al.

ACS Chemical Biology, 2022, 17 (7), pp.1638-1657. ⟨10.1021/acschembio.2c00307⟩

Article dans une revue hal-03836746v1
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Dihydrouridine synthesis in tRNAs is under reductive evolution in Mollicutes

Bruno Faivre , Murielle Lombard , Soufyan Fakroun , Chau-Duy-Tam Vo , Catherine Goyenvalle et al.

RNA Biology, 2021, 18 (12), pp.2278 - 2289. ⟨10.1080/15476286.2021.1899653⟩

Article dans une revue hal-03837152v1

tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila

Margarita Angelova , Dilyana G Dimitrova , Bruno Da silva , Virginie Marchand , Caroline Jacquier et al.

Nucleic Acids Research, 2020, 48 (4), pp.2050-2072. ⟨10.1093/nar/gkaa002⟩

Article dans une revue hal-02445153v1
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Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168

Valerie de Crecy-Lagard , Robert J. Ross , Marshall Jaroch , Virginie Marchand , Christina Eisenhart et al.

Biomolecules, 2020, 10 (7), pp.977. ⟨10.3390/biom10070977⟩

Article dans une revue hal-02915956v1
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Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes

Pascal Sirand-Pugnet , Damien Brégeon , Laure Béven , Catherine Goyenvalle , Alain Blanchard et al.

Biomolecules, 2020, 10 (4), pp.587. ⟨10.3390/biom10040587⟩

Article dans une revue hal-02547879v1
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Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario

Charles Bou-Nader , Hugo Montémont , Vincent Guérineau , Olivier Jean-Jean , Damien Brégeon et al.

Nucleic Acids Research, 2018, 46 (3), pp.1386-1394. ⟨10.1093/nar/gkx1294⟩

Article dans une revue hal-01727508v1
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Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases

Charles Bou-Nader , Damien Brégeon , Ludovic Pecqueur , Marc Fontecave , Djemel Hamdane

Biochemistry, 2018, 57 (37), pp.5407-5414. ⟨10.1021/acs.biochem.8b00584⟩

Article dans une revue hal-01896983v1
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An extended dsRBD is required for post-transcriptional modification in human tRNAs

Charles Bou-Nader , Ludovic Pecqueur , Damien Bregeon , Amina Kamah , Vincent Guérineau et al.

Nucleic Acids Research, 2015, 43 (19), pp.9446-9456. ⟨10.1093/nar/gkv989⟩

Article dans une revue hal-01279196v1

Transcriptional mutagenesis: causes and involvement in tumour development

Damien Brégeon , Paul Doetsch

Nature Reviews Cancer, 2011, 11 (3), pp.218-227. ⟨10.1038/nrc3006⟩

Article dans une revue hal-03980890v1

A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA

Benoit Desmolaize , Céline Fabret , Damien Brégeon , Simon Rose , Henri Grosjean et al.

Nucleic Acids Research, 2011, 39 (21), pp.9368-9375. ⟨10.1093/nar/gkr626⟩

Article dans une revue (data paper) hal-03978959v1

Transcriptional mutagenesis: causes and involvement in tumour development.

Damien Brégeon , Paul W Doetsch

Nature Reviews Cancer, 2011, 11 (3), pp.218-27. ⟨10.1038/nrc3006⟩

Article dans une revue hal-00574260v1

Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells.

Damien Brégeon , Paul-Antoine Peignon , Alain Sarasin

PLoS Genetics, 2009, 5 (7), pp.e1000577. ⟨10.1371/journal.pgen.1000577⟩

Article dans une revue hal-00408934v1

Transcriptional Mutagenesis Induced by 8-Oxoguanine in Mammalian Cells

Damien Brégeon , Paul-Antoine Peignon , Alain Sarasin

PLoS Genetics, 2009, 5 (7), pp.e1000577. ⟨10.1371/journal.pgen.1000577⟩

Article dans une revue hal-03980899v1

Thiazolinium and imidazolium chiral ionic liquids derived from natural amino acid derivatives

D. Brégeon , Jocelyne Levillain , F. Guillen , Jean-Christophe Plaquevent , A.-C. Gaumont

Amino Acids, 2008, 35 (1), pp.175. ⟨10.1007/s00726-007-0575-3⟩

Article dans une revue istex hal-01147106v1

Assays for Transcriptional Mutagenesis in Active Genes

Damien Brégeon , Paul Doetsch

Methods in Enzymology, 2006, Methods in Enzymology, 409, pp.345-357. ⟨10.1016/s0076-6879(05)09020-8⟩

Article dans une revue (data paper) hal-03979110v1

Hypothetical role of RNA damage avoidance in preventing human disease

Damien Brégeon , Alain Sarasin

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005, 577 (1-2), pp.293-302. ⟨10.1016/j.mrfmmm.2005.04.002⟩

Article dans une revue (data paper) istex hal-03979122v1

Reliable method for generating double-stranded DNA vectors containing site-specific base modifications

Damien Brégeon , Paul Doetsch

Biotechniques, 2004, 37 (5), pp.760-766. ⟨10.2144/04375st01⟩

Article dans une revue (data paper) hal-03979129v1

Transcriptional Mutagenesis Induced by Uracil and 8-Oxoguanine in Escherichia coli

Damien Brégeon , Zara Doddridge , Ho Jin You , Bernard Weiss , Paul Doetsch

Molecular Cell, 2003, 12 (4), pp.959-970. ⟨10.1016/s1097-2765(03)00360-5⟩

Article dans une revue (data paper) hal-03979135v1

Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift

Damien Brégeon , Vincent Colot , Miroslav Radman , François Taddei

Genes and Development, 2001, 15 (17), pp.2295-2306. ⟨10.1101/gad.207701⟩

Article dans une revue (data paper) hal-03979139v1

Inefficient mismatch repair: genetic defects and down regulation

Damien Brégeon , Ivan Matic , Miroslav Radman , François Taddei

Journal of Genetics, 1999, 78 (1), pp.21-28. ⟨10.1007/BF02994699⟩

Article dans une revue (data paper) istex hal-03979141v1