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David Alexandre Gross

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Neuropilin-1 cooperates with PD-1 in CD8+ T cells predicting outcomes in melanoma patients treated with anti-PD1

Julien Rossignol , Zakia Belaid , Guillemette Fouquet , Flavia Guillem , Rachel Rignault
iScience, 2022, 25 (6), pp.104353. ⟨10.1016/j.isci.2022.104353⟩
Journal articles hal-03842485v1

Overcoming the Challenges Imposed by Humoral Immunity to AAV Vectors to Achieve Safe and Efficient Gene Transfer in Seropositive Patients

David-Alexandre Gross , Novella Tedesco , Christian Leborgne , Giuseppe Ronzitti
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.857276⟩
Journal articles hal-03640310v1
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Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates

Helena Costa-Verdera , Fanny Collaud , Christopher R Riling , Pauline Sellier , Jayme M L Nordin
Nature Communications, 2021, 12 (1), pp.6393. ⟨10.1038/s41467-021-26744-4⟩
Journal articles hal-03449262v1
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A combination of cyclophosphamide and interleukin-2 allows CD4 1 T cells converted to Tregs to control scurfy syndrome

Marianne Delville , Florence Bellier , Juliette Leon , Roman Klifa , Sabrina Lizot
Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Journal articles hal-04416555v1

Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates

Helena Costa-Verdera , Fanny Collaud , Christopher Riling , Pauline Sellier , Jayme Nordin
Nature Communications, 2021, 12 (1), pp.6393. ⟨10.1038/s41467-021-26744-4⟩
Journal articles hal-04324265v1
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A combination of cyclophosphamide and interleukin-2 allows CD4+ T cells converted to Tregs to control scurfy syndrome

Marianne Delville , Florence Bellier , Juliette Leon , Roman Klifa , Sabrina Lizot
Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Journal articles hal-03588460v1
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A combination of cyclophosphamide and interleukin-2 allows CD4 1 T cells converted to Tregs to control scurfy syndrome

Marianne Delville , Florence Bellier , Juliette Leon , Roman Klifa , Sabrina Lizot
Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Journal articles hal-04417449v1

Human Immune Responses to Adeno-Associated Virus (AAV) Vectors

Giuseppe Ronzitti , David-Alexandre Gross , Federico Mingozzi
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.00670⟩
Journal articles hal-04363711v1

Of rAAV and Men: From Genetic Neuromuscular Disorder Efficacy and Toxicity Preclinical Studies to Clinical Trials and Back

Laurine Buscara , David-Alexandre Gross , Nathalie Daniele
Journal of Personalized Medicine, 2020, 10 (4), pp.258. ⟨10.3390/jpm10040258⟩
Journal articles hal-04363708v1
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IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

Irini Evnouchidou , Pascal Chappert , Samira Benadda , Andrés Ernesto Zucchetti , Mirjana Weimershaus
Nature Communications, 2020, 11 (1), pp.2779. ⟨10.1038/s41467-020-16471-7⟩
Journal articles hal-02867476v1

Dual muscle-liver transduction imposes immune tolerance for muscle transgene engraftment despite preexisting immunity

Laurent Bartolo , Stéphanie Li Chung Tong , Pascal Chappert , Dominique Urbain , Fanny Collaud
JCI Insight, 2019, 4 (11), pii: 127008. ⟨10.1172/jci.insight.127008⟩
Journal articles hal-02332827v1
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Foxp3+ Regulatory and Conventional CD4+ T Cells Display Similarly High Frequencies of Alloantigen-Reactive Cells

Mélanie Lalfer , Pascal Chappert , Maxime Carpentier , Dominique Urbain , Jean Davoust
Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.00521⟩
Journal articles hal-02392758v1
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Dual muscle-liver transduction imposes immune tolerance for muscle transgene engraftment despite preexisting immunity

Laurent Bartolo , Stéphanie Li Chung Tong , Pascal Chappert , Dominique Urbain , Fanny Collaud
JCI Insight, 2019, 4 (11), pii: 127008. ⟨10.1172/jci.insight.127008⟩
Journal articles hal-04324422v1
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Cross-Presentation of Skin-Targeted Recombinant Adenoassociated Virus 2/1 Transgene Induces Potent Resident Memory CD8 ؉ T Cell Responses

David-Alexandre Gross , Alexandre Ghenassia , Laurent Bartolo , Dominique Urbain , Sofia Benkhelifa-Ziyyat
Journal of Virology, 2019, 93 (5), pp.e01334-18. ⟨10.1128/JVI.01334-18⟩
Journal articles hal-03827009v1
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Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node

Ruby Alonso , Héloïse Flament , Sébastien Lemoine , Christine Sedlik , Emanuel Bottasso
Nature Communications, 2018, 9, pp.2113. ⟨10.1038/s41467-018-04524-x⟩
Journal articles hal-01976612v1

Intradermal Immunization with rAAV1 Vector Induces Robust Memory CD8+ T Cell Responses Independently of Transgene Expression in DCs

Alexandre Ghenassia , David-Alexandre Gross , Stéphanie Lorain , Fabiola Tros , Dominique Urbain
Molecular Therapy, 2017, 25 (10), pp.2309-2322. ⟨10.1016/j.ymthe.2017.06.019⟩
Journal articles hal-03846034v1

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia

Amélie Trinquand , Nuno R. Dos Santos , Christine Tran Quang , Francesca Rocchetti , Benedetta Zaniboni
Cancer Discovery, 2016, 6 (9), pp.972-985. ⟨10.1158/2159-8290.CD-15-0675⟩
Journal articles hal-01460133v1

Intrinsic Transgene Immunogenicity Gears CD8+ T-cell Priming After rAAV-Mediated Muscle Gene Transfer

Maxime Carpentier , Stéphanie Lorain , Pascal Chappert , Mélanie Lalfer , Romain Hardet
Molecular Therapy, 2015, 23 (4), pp.697-706. ⟨10.1038/mt.2014.235⟩
Journal articles hal-02407918v1

Prolonged Gene Expression in Muscle Is Achieved Without Active Immune Tolerance Using MicrorRNA 142.3p-Regulated rAAV Gene Transfer

Florence Boisgérault , David-Alexandre Gross , Maxime Ferrand , Jérôme Poupiot , Sylvie Darocha
Human Gene Therapy, 2013, 24 (4), pp.393-405. ⟨10.1089/hum.2012.208⟩
Journal articles hal-02338036v1

Extrathymic induction of Foxp3⁺ regulatory T cells declines with age in a T-cell intrinsic manner.

Maxime Carpentier , Pascal Chappert , Chantal Kuhn , Mélanie Lalfer , Héloïse Flament
European Journal of Immunology, 2013, 43 (10), pp.2598-604. ⟨10.1002/eji.201343532⟩
Journal articles pasteur-00912507v1

Induction of multiple CD8+ T cell responses against the inducible Hsp70 employing an Hsp70 oligoepitope peptide.

Olivier Faure , Stéphanie Graff-Dubois , Pedro M S Alves , Sébastien Cornet , Marie-Thérèse Duffour
Oncology Reports, 2007, 17 (3), pp.679-85. ⟨10.3892/or.17.3.679⟩
Journal articles pasteur-00166658v1
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Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

Julie Cabarrocas , Cécile Cassan , Fay Magnusson , Eliane Piaggio , Lennart T. Mars
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (22), pp.8453-8458. ⟨10.1073/pnas.0603086103⟩
Journal articles hal-03095902v1

A lentiviral vector encoding the human Wiskott–Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice

S Charrier , D Stockholm , K Seye , P Opolon , M Taveau
Gene Therapy, 2005, 12 (7), pp.597-606. ⟨10.1038/sj.gt.3302440⟩
Journal articles hal-03765538v1

Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice.

Philippe Nizard , David-Alexandre Gross , Aurélie Babon , Alexandre Chenal , Bruno Beaumelle
Journal of Immunotherapy, 2003, 26 (1), pp.63-71. ⟨10.1097/00002371-200301000-00007⟩
Journal articles hal-02998464v1