David Alexandre Gross

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Publications

Synergism of dual AAV gene therapy and rapamycin rescues GSDIII phenotype in muscle and liver

Louisa Jauze , Mallaury Vie , Quentin Miagoux , Lucille Rossiaud , Patrice Vidal et al.

JCI Insight, 2024, 9 (11), pp.e172614. ⟨10.1172/jci.insight.172614⟩

Article dans une revue hal-05216074v1
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Muscle‐specific, liver‐detargeted adeno‐associated virus gene therapy rescues Pompe phenotype in adult and neonate Gaa −/− mice

P. Sellier , P. Vidal , B. Bertin , E. Gicquel , E Bertil‐froidevaux et al.

Journal of Inherited Metabolic Disease, 2023, 47 (1), pp.119-134. ⟨10.1002/jimd.12625⟩

Article dans une revue hal-04795500v1

COVID-19 in patients with neuroendocrine neoplasms: 2-year results of the INTENSIVE study

Nicola Fazio , Lorenzo Gervaso , Thorvardur Halfdanarson , Mohamad Sonbol , Rachel Eiring et al.

Endocrine-Related Cancer, 2023, 30 (6), ⟨10.1530/erc-22-0395⟩

Article dans une revue hal-04489844v1

Overcoming the Challenges Imposed by Humoral Immunity to AAV Vectors to Achieve Safe and Efficient Gene Transfer in Seropositive Patients

David-Alexandre Gross , Novella Tedesco , Christian Leborgne , Giuseppe Ronzitti

Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.857276⟩

Article dans une revue hal-03640310v1
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Neuropilin-1 cooperates with PD-1 in CD8+ T cells predicting outcomes in melanoma patients treated with anti-PD1

Julien Rossignol , Zakia Belaid , Guillemette Fouquet , Flavia Guillem , Rachel Rignault et al.

iScience, 2022, 25 (6), pp.104353. ⟨10.1016/j.isci.2022.104353⟩

Article dans une revue hal-03842485v1
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A combination of cyclophosphamide and interleukin-2 allows CD4+ T cells converted to Tregs to control scurfy syndrome

Marianne Delville , Florence Bellier , Juliette Leon , Roman Klifa , Sabrina Lizot et al.

Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩

Article dans une revue hal-03588460v1
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Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates

Helena Costa-Verdera , Fanny Collaud , Christopher R Riling , Pauline Sellier , Jayme M L Nordin et al.

Nature Communications, 2021, 12 (1), pp.6393. ⟨10.1038/s41467-021-26744-4⟩

Article dans une revue hal-03449262v1
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A combination of cyclophosphamide and interleukin-2 allows CD4 1 T cells converted to Tregs to control scurfy syndrome

Marianne Delville , Florence Bellier , Juliette Leon , Roman Klifa , Sabrina Lizot et al.

Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩

Article dans une revue hal-04416555v1

Human Immune Responses to Adeno-Associated Virus (AAV) Vectors

Giuseppe Ronzitti , David-Alexandre Gross , Federico Mingozzi

Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.00670⟩

Article dans une revue hal-04363711v1

Of rAAV and Men: From Genetic Neuromuscular Disorder Efficacy and Toxicity Preclinical Studies to Clinical Trials and Back

Laurine Buscara , David-Alexandre Gross , Nathalie Daniele

Journal of Personalized Medicine, 2020, 10 (4), pp.258. ⟨10.3390/jpm10040258⟩

Article dans une revue hal-04363708v1
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IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

Irini Evnouchidou , Pascal Chappert , Samira Benadda , Andrés Ernesto Zucchetti , Mirjana Weimershaus et al.

Nature Communications, 2020, 11 (1), pp.2779. ⟨10.1038/s41467-020-16471-7⟩

Article dans une revue hal-02867476v1
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Foxp3+ Regulatory and Conventional CD4+ T Cells Display Similarly High Frequencies of Alloantigen-Reactive Cells

Mélanie Lalfer , Pascal Chappert , Maxime Carpentier , Dominique Urbain , Jean Davoust et al.

Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.00521⟩

Article dans une revue hal-02392758v1

Induction of tumor-specific CTL responses using the C-terminal fragment of Viral protein R as cell penetrating peptide

D A Gross , C Leborgne , P Chappert , C Masurier , M Leboeuf et al.

Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-40594-7⟩

Article dans une revue hal-02362867v1
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Dual muscle-liver transduction imposes immune tolerance for muscle transgene engraftment despite preexisting immunity

Laurent Bartolo , Stéphanie Li Chung Tong , Pascal Chappert , Dominique Urbain , Fanny Collaud et al.

JCI Insight, 2019, 4 (11), pii: 127008. ⟨10.1172/jci.insight.127008⟩

Article dans une revue hal-04324422v1
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Cross-Presentation of Skin-Targeted Recombinant Adenoassociated Virus 2/1 Transgene Induces Potent Resident Memory CD8 ؉ T Cell Responses

David-Alexandre Gross , Alexandre Ghenassia , Laurent Bartolo , Dominique Urbain , Sofia Benkhelifa-Ziyyat et al.

Journal of Virology, 2019, 93 (5), pp.e01334-18. ⟨10.1128/JVI.01334-18⟩

Article dans une revue hal-03827009v1
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Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node

Ruby Alonso , Héloïse Flament , Sébastien Lemoine , Christine Sedlik , Emanuel Bottasso et al.

Nature Communications, 2018, 9, pp.2113. ⟨10.1038/s41467-018-04524-x⟩

Article dans une revue hal-01976612v1

Intradermal Immunization with rAAV1 Vector Induces Robust Memory CD8+ T Cell Responses Independently of Transgene Expression in DCs

Alexandre Ghenassia , David-Alexandre Gross , Stéphanie Lorain , Fabiola Tros , Dominique Urbain et al.

Molecular Therapy, 2017, 25 (10), pp.2309-2322. ⟨10.1016/j.ymthe.2017.06.019⟩

Article dans une revue hal-03846034v1

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia

Amélie Trinquand , Nuno R. Dos Santos , Christine Tran Quang , Francesca Rocchetti , Benedetta Zaniboni et al.

Cancer Discovery, 2016, 6 (9), pp.972-985. ⟨10.1158/2159-8290.CD-15-0675⟩

Article dans une revue hal-01460133v1

Intrinsic Transgene Immunogenicity Gears CD8+ T-cell Priming After rAAV-Mediated Muscle Gene Transfer

Maxime Carpentier , Stéphanie Lorain , Pascal Chappert , Mélanie Lalfer , Romain Hardet et al.

Molecular Therapy, 2015, 23 (4), pp.697-706. ⟨10.1038/mt.2014.235⟩

Article dans une revue hal-02407918v1

Extrathymic induction of Foxp3⁺ regulatory T cells declines with age in a T-cell intrinsic manner.

Maxime Carpentier , Pascal Chappert , Chantal Kuhn , Mélanie Lalfer , Héloïse Flament et al.

European Journal of Immunology, 2013, 43 (10), pp.2598-604. ⟨10.1002/eji.201343532⟩

Article dans une revue pasteur-00912507v1

Prolonged Gene Expression in Muscle Is Achieved Without Active Immune Tolerance Using MicrorRNA 142.3p-Regulated rAAV Gene Transfer

Florence Boisgérault , David-Alexandre Gross , Maxime Ferrand , Jérôme Poupiot , Sylvie Darocha et al.

Human Gene Therapy, 2013, 24 (4), pp.393-405. ⟨10.1089/hum.2012.208⟩

Article dans une revue hal-02338036v1

MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV

M. Sudres , S. Cire , V. Vasseur , L. Brault , S. da Rocha et al.

Molecular Therapy, 2012, 20 (8), pp.1571-81. ⟨10.1038/mt.2012.101⟩

Article dans une revue hal-02881210v1

Induction of multiple CD8+ T cell responses against the inducible Hsp70 employing an Hsp70 oligoepitope peptide.

Olivier Faure , Stéphanie Graff-Dubois , Pedro M S Alves , Sébastien Cornet , Marie-Thérèse Duffour et al.

Oncology Reports, 2007, 17 (3), pp.679-85. ⟨10.3892/or.17.3.679⟩

Article dans une revue pasteur-00166658v1
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Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

Julie Cabarrocas , Cécile Cassan , Fay Magnusson , Eliane Piaggio , Lennart T. Mars et al.

Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (22), pp.8453-8458. ⟨10.1073/pnas.0603086103⟩

Article dans une revue hal-03095902v1

A lentiviral vector encoding the human Wiskott–Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice

S Charrier , D Stockholm , K Seye , P Opolon , M Taveau et al.

Gene Therapy, 2005, 12 (7), pp.597-606. ⟨10.1038/sj.gt.3302440⟩

Article dans une revue hal-03765538v1

Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice.

Philippe Nizard , David-Alexandre Gross , Aurélie Babon , Alexandre Chenal , Bruno Beaumelle et al.

Journal of Immunotherapy, 2003, 26 (1), pp.63-71. ⟨10.1097/00002371-200301000-00007⟩

Article dans une revue hal-02998464v1