David DUBAYLE (PhD, HDR)

Maître de Conférences en Biologie cellulaire
8
Documents
Affiliations actuelles
  • Université Paris Cité (UPCité)
  • Centre Neurosciences intégratives et Cognition / Integrative Neuroscience and Cognition Center (INCC - UMR 8002)
Identifiants chercheurs

Présentation

Après un Doctorat en Neurosciences et Pharmacologie de l'Université de Bordeaux et un post-Doctorat en Neuroanatomie au Collège de France à Paris, j'ai intégré l'actuelle Université Paris Cité / UFR des Sciences Fondamentales & Biomédicales en 2001 sur un poste de Maître de Conférences en Biologie cellulaire et soutenu une Habilitation à Diriger des Recherches en Sciences de la vie et de la Santé en 2007. Palmes académiques en 2012.

https://biomedicale.u-paris.fr/

=> Dans des modèles murins exposés à des altérations gravitaires ou reproduisant les effets physiologiques des vols spatiaux, j'étudie les régulations de l’ouverture / fermeture de la Barrière Hémato-Encéphalique. Ces travaux de recherches (CNRS UMR 8002 / Integrative Neurosciences & Cognition Center) sont en partie financés par le CNES depuis 2014. Les 8 articles sur les 10 dernières années sont disponibles, ci-dessous, par téléchargement.

https://incc-paris.fr/


Liste complète des publications

28- DUBAYLE D., VANDEN-BOSSCHE A., PEIXOTO T., MOREL J.L. (2023). “Hypergravity Increases Blood-Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice”. Cells. (IF: 7,66), 12; 734-51.

27- HERON A., PAPILLON V., DUBAYLE D. (2021). “Medical, neurobiological, and psychobehavioral perspectives of mastocytosis: a case report”. J Med Case Rep. (IF: 0,88), 15; 176-82.

26- DUBAYLE D., VANDEN-BOSSCHE A., BERANECK M., VICO L., MOREL J.L. (2020). “Effects of centrifugation and whole-body vibrations on blood-brain barrier permeability in mice”. NPJ Microgravity (IF: 3,1), 6; 1-7.

25- HERON A., LEROUX C. and DUBAYLE D. (2019). “Use of placebo in French hospitals: data from polyvalent medicine units”. Médecine Sciences (Paris) (IF: 0,68), 35; 674-681.

24- LAMBERT L., DUBAYLE D., FAFOURI A., HERZOG E., CSABA Z., DOURNAUD P., EL MESTIKAWY S. and BERNARD V. (2018). “Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway”. Front Cell Neurosci (IF: 4,3), 12; 1-17.

23- HARLE G., KAMINSKI S., DUBAYLE D., FRIPPIAT J.P. and ROPARS A. (2018). “Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response”. Scientific Reports (IF: 4,847), 143: 1-10.

22- AL AMIR I., DUBAYLE D., HERON A., DELAYRE-ORTHEZ C. and ANTON P.M. (2017). “Maillard reaction products from highly heated food prevent mast cell number increase and inflammation in a mouse model of colitis”. Nutrition Research (IF: 2,737), 48: 26-32.

21- BOURSEREAU R., DONADIEU A., DABERTRAND F., DUBAYLE D. and MOREL J.L. (2015). “Blood brain barrier precludes the cerebral arteries to intravenously injected antisense oligonucleotide”. European Journal of Pharmacology (IF: 2,754), 747: 141-149.

20- HERON A. and DUBAYLE D. (2013). “A focus on mast cells and pain”. Journal of Neuroimmunology (IF: 3,033), 264: 1-7.

19- DUBAYLE D. and HERON A. (2012). “Decrease of cerebral mast cell degranulation after systemic administration of lipopolysaccharide”. Inflammation Research (IF: 2,109), 61: 1295-7.

18- ROSSIGNOL J., BOYER C., THINARD R., REMY S., DUGAST A.S., DUBAYLE D., DEY N.D., BOEFFARD F., DELECRIN J., HEYMANN D., VANDHOVE B., ANEGON I., NAVEILHAN P., DUNBAR G.L. and LESCAUDRON L (2009). “Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation”. Journal of Cellular and Molecular Medicine (IF: 4,608), 13: 2547-58.

17- BEGHDADI W., PORCHERIE A., SCHNEIDER B., MORISSET S., DUBAYLE D., PERONET R., DY M., LOUIS J., ARRANG J.M., and MECHERI S (2009). “Histamine H(3) receptor-mediated signaling protects mice from cerebral malaria”. PLoS ONE (IF: 4,411), 4(6): e6004.

16- BEGHDADI W., PORCHERIE A., SCHNEIDER B.S., DUBAYLE D., PERONET R., HUERRE M., WATANABE T., OHTSU H., LOUIS J. et MECHERI S. (2009) “Rôle de l’histamine et des récepteurs histaminiques dans la pathogénèse du paludisme”. Médecine Sciences (Paris) (IF: 0,64), 25: 377-381.

15- BEGHDADI W., PORCHERIE A., SCHNEIDER B., DUBAYLE D., PERONET R., HUERRE M., WATANABE T., OHTSU H., LOUIS J. and MECHERI S. (2008). “Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease”. Journal of Experimental Medicine (IF: 14,776), 205: 395-408.

14- DUBAYLE D., SERVIERE J. and MENETREY D (2007). “The effects of viscero-somatic interactions on thalamic mast cell recruitment in cystitic rats”. Journal of Neuroimmunology (IF: 2,901), 190: 18-27.

13- UGOLINI G., KLAM F., DOLDAN DANS M., DUBAYLE D., BRANDI A.M., BÜTTNER-ENNEVER J. and GRAF W. (2006) “Horizontal eye movement networks in primates as revealed by retrograde transneuronal transfer of rabies virus: differences in monosynaptic input to « slow » and « fast » abducens motoneurons”. Journal of Comparative Neurology (IF: 3,774), 498: 762-85.

12- DUBAYLE D., MALISSIN I. and MENETREY D. (2005) “Differential effects of two analgesic drugs, morphine chlorhydrate and acetylsalicylic acid, on thalamic mast cell numbers in rat”. Journal of Neuroimmunology (IF: 2,901), 169: 106-15.

11- DUBAYLE D., SERVIERE J. and MENETREY D. (2005) “Evidence for serotonin influencing the thalamic infiltration of mast cells in rat”. Journal of Neuroimmunology (IF: 2,901), 159: 20-30.

10- MENETREY D. and DUBAYLE D. (2003) “A one-step dual-labeling method for antigen detection in mast cells”. Histochemistry and Cell Biology (IF: 4,727), 120: 435-442.

9- SERVIERE J., DUBAYLE D. and MENETREY D. (2003) “Increase of rat medial habenular mast cell numbers by systemic administration of cyclophosphamide”. Toxicology Letters (IF: 3,581), 145: 143-152.

8- GRANTYN A., BRANDI A.M., DUBAYLE D., GRAF W., UGOLINI G., HADJIDIMITRAKIS K. and MOSCHOVAKIS A.K. (2002) “Density gradients of trans-synaptically labeled collicular neurons after injections of rabies virus in the lateral rectus muscle of rhesus monkey”. Journal of Comparative Neurology (IF: 3,774), 451: 346-361.

7- BUHOT M.C., DUBAYLE D., MALLERET G., JAVERZAT S. and SEGU L. (2001) “Exploration, anxiety and spatial memory in transgenic anophtalmic mice”. Behavioural Neurosciences (IF: 2,481), 115: 455-467.

6- ROUSSEAU B., DUBAYLE D., SENNLAUB F., JEANNY J.C., COSTET P., BIKFALVI A., and JAVERZAT S. (2000) “Neural and angiogenic defects in eyes of transgenic mice expressing a dominant-negative FGF receptor in the pigment cells”. Experimental Eye Research (IF: 2,817), 71: 395-404.

5- DUBAYLE D. and VIALA D. (1998) “ Effects of CO2 and H+ on spinal respiratory activity in vitro”. Brain Research Bulletin (IF: 2,498), 45: 83-87.

4- DUBAYLE D. and VIALA D. (1998) “Entrainment of the medullary generator by electrical stimulations in the cervical grey matter from in vitro preparations of newborn rats”. Neuroscience letters (IF: 2,055), 248: 204-208.

3- DUBAYLE D. and VIALA D. (1996) “Localisation of the spinal respiratory rhythm generator by an in vitro electrophysiological approach”. NeuroReport (IF: 1,822), 7: 1175-1180.

2- DUBAYLE D. and VIALA D. (1996) “Interactions between medullary and spinal respiratory rhythm generators in the in vitro brainstem spinal cord preparations from newborn rats”. Experimental Brain Research (IF: 2,817), 109: 1-8.

1- DUBAYLE D. et VIALA D. (1993) “Possible existence of spinal inspiratory activity in the in vitro brain stem-spinal cord preparation from newborn rats”. C.R. Acad. Sci. III (IF: 1,603), 316: 1458-1462.

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Enseignement : Biologie cellulaire Recherche : Neurosciences Neuroanatomie

Publications

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Publications

Image document

Hypergravity Increases Blood–Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice

David Dubayle , Arnaud Vanden-Bossche , Tom Peixoto , Jean Luc Morel
Cells, 2023, 12 (5), ⟨10.3390/cells12050734⟩
Article dans une revue hal-04086641 v2
Image document

Medical, neurobiological, and psychobehavioral perspectives of mastocytosis: a case report

Anne Héron , V. Papillon , D. Dubayle
Journal of Medical Case Reports, 2021, 15 (1), pp.176. ⟨10.1186/s13256-021-02757-x⟩
Article dans une revue hal-03988335 v1
Image document

Effects of centrifugation and whole-body vibrations on blood–brain barrier permeability in mice

David Dubayle , Arnaud Vanden-Bossche , Mathieu Beraneck , Laurence Vico , Jean-Luc Morel
NPJ Microgravity, 2020, 6 (1), ⟨10.1038/s41526-019-0094-z⟩
Article dans une revue hal-03006942 v1
Image document

Le placebo à l’hôpital

Anne Héron , Christophe Leroux , David Dubayle
Médecine/Sciences, 2019, 35 (8-9), pp.674-681. ⟨10.1051/medsci/2019127⟩
Article dans une revue hal-02292978 v1
Image document

Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway

Lisa Lambert , David Dubayle , Assia Fafouri , Etienne Herzog , Zsolt Csaba et al.
Frontiers in Cellular Neuroscience, 2018, 12, pp.450. ⟨10.3389/fncel.2018.00450⟩
Article dans une revue hal-01977271 v1
Image document

Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response

Guillaume Harlé , Sandra Kaminski , David Dubayle , Jean-Pol Frippiat , Armelle Ropars
Scientific Reports, 2018, 8 (1), pp.143. ⟨10.1038/s41598-017-18401-y⟩
Article dans une revue hal-04734856 v1
Image document

Maillard Reaction Products from highly heated food prevent mast cell number increase and inflammation in a mouse model of colitis

Issam Al Amir , David Dubayle , Anne Héron , Carine Delayre-Orthez , Pauline M. Anton
Nutrition Research, 2017, 46, pp.26-32. ⟨10.1016/j.nutres.2017.10.005⟩
Article dans une revue hal-01625889 v1
Image document

Blood brain barrier precludes the cerebral arteries to intravenously-injected antisense oligonucleotide

Raphael Boursereau , Arnaud Donadieu , Fabrice Dabertrand , David Dubayle , Jean-Luc Morel
European Journal of Pharmacology, 2015, 747, pp.141-149. ⟨10.1016/j.ejphar.2014.11.027⟩
Article dans une revue hal-04592438 v1