David Godefroy

58
Documents

Publications

Publications

SELENOPROTEIN T deficiency alters projection neuron migration during corticogenesis in mice

Emmanuelle Carpentier , Anthony Falluel-Morel , Lisa Brunet , Magalie Bénard , David Alexandre et al.
Neuroscience, 2025, 585, pp.323-334. ⟨10.1016/j.neuroscience.2025.09.015⟩
Article dans une revue hal-05326228 v1

Whole body distribution of the regulatory peptide 26RFa in male and female mice

Marie Picot , Mélodie Devère , Saloua Takhlidjt , Corentin Guillemot , Caroline Lusurier et al.
Peptides, 2025, 190, pp.171417. ⟨10.1016/j.peptides.2025.171417⟩
Article dans une revue (data paper) hal-05326224 v1

Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells

Lisa Brunet , David Alexandre , Jiyoung Lee , Maria del Mar Blanquer-Rosselló , David Bracquemond et al.
Nature Communications, 2025, 16 (1), pp.7853. ⟨10.1038/s41467-025-61788-w⟩
Article dans une revue hal-05292896 v1
Image document

The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice

Martin Pedard , Lucie Prevost , Camille Carpena , Brian Holleran , Laurence Desrues et al.
Nature Communications, 2024, 15 (1), pp.8430. ⟨10.1038/s41467-024-52654-2⟩
Article dans une revue hal-04766828 v1

Single-Cell RNA Sequencing Identifies Response of Renal Lymphatic Endothelial Cells to Acute Kidney Injury

Heidi A. Creed , Saranya Kannan , Brittany L. Tate , David Godefroy , Priyanka Banerjee et al.
Journal of the American Society of Nephrology, 2024, 35 (5), pp.549-565. ⟨10.1681/ASN.0000000000000325⟩
Article dans une revue hal-05155866 v1

SELENOT deficiency in the mouse brain impacts catecholaminergic neuron density: an immunohistochemical, in situ hybridization and 3D light-sheet imaging study

David Godefroy , Loubna Boukhzar , Ben Yamine Mallouki , Emmanuelle Carpentier , Christophe Dubessy et al.
Neuroendocrinology, 2023, 113 (2), pp.193-207. ⟨10.1159/000522091⟩
Article dans une revue hal-03666802 v1
Image document

Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure

Coraline Heron , Anais Dumesnil , Mahmoud Houssari , Sylvanie Renet , Theo Lemarcis et al.
Cardiovascular Research, 2023, 119 (2), pp.492-505. ⟨10.1093/cvr/cvac086⟩
Article dans une revue (data paper) inserm-04113422 v1
Image document

Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models

Ifat Alsharif , Loubna Boukhzar , Benjamin Lefranc , David Godefroy , Juliette Aury-Landas et al.
Redox Biology, 2021, 40, pp.101839. ⟨10.1016/j.redox.2020.101839⟩
Article dans une revue hal-03132187 v1

Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction

Mahmoud Houssari , Anais Dumesnil , Virginie Tardif , Riikka Kivelä , Nathalie Pizzinat et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (7), pp.1722-1737. ⟨10.1161/ATVBAHA.120.314370⟩
Article dans une revue hal-03553406 v1

Three-dimensional mapping of tyrosine hydroxylase in the transparent brain and adrenal of prenatal and pre-weaning mice: Comprehensive methodological flowchart and quantitative aspects of 3D mapping

David Godefroy , Loubna Boukhzar , Christophe Dubessy , Maïté Montero-Hadjadje , Laurent Yon et al.
Journal of Neuroscience Methods, 2020, 335, pp.108596. ⟨10.1016/j.jneumeth.2020.108596⟩
Article dans une revue hal-02485649 v1
Image document

Glucose homeostasis is impaired in mice deficient in the neuropeptide 26RFa (QRFP)

Mouna El-Mehdi , Saloua Takhlidjt , Fayrouz Khiar , Gaëtan Prévost , Jean-Luc Do Rego et al.
BMJ Open Diab Res Care, 2020, 8 (1), pp.2019-000942. ⟨10.1136/bmjdrc-2019-000942⟩
Article dans une revue hal-02884077 v1

Tyrosine-hydroxylase immunoreactivity in the mouse transparent brain and adrenal glands

David Godefroy , William Rostène , Youssef Anouar , Annabelle Reaux-Le Goazigo
Journal of Neural Transmission, 2018
Article dans une revue hal-01944579 v1
Image document

Cone degeneration is triggered by the absence of USH1 proteins but prevented by antioxidant treatments

Alix Trouillet , Elisabeth Dubus , Julie Degardin , Amrit Estivalet , Ivana Ivkovic et al.
Scientific Reports, 2018, 8 (1), pp.1968. ⟨10.1038/s41598-018-20171-0⟩
Article dans une revue hal-01708801 v1

Hyperosmolarity and Benzalkonium Chloride Differently Stimulate Inflammatory Markers in Conjunctiva-Derived Epithelial Cells in vitro

Elise Warcoin , Chloé Clouzeau , Christophe Roubeix , Anne-Laure Raveu , David Godefroy et al.
Ophthalmic Research, 2017, 58 (1), pp.40-48
Article dans une revue hal-01945327 v1
Image document

Tridimensional Visualization and Analysis of Early Human Development

Morgane Belle , David Godefroy , Gérard Couly , Samuel A. Malone , Francis Collier et al.
Cell, 2017, 169 (1), pp.161-173.e12. ⟨10.1016/j.cell.2017.03.008⟩
Article dans une revue hal-01497677 v1
Image document

Bilateral neuroinflammatory processes in visual pathways induced by unilateral ocular hypertension in the rat

Anaïs Sapienza , Anne-Laure Raveu , Elodie Reboussin , Christophe Roubeix , Céline Boucher et al.
Journal of Neuroinflammation, 2016, 13 (1), pp.44. ⟨10.1186/s12974-016-0509-7⟩
Article dans une revue hal-01282014 v1
Image document

Ocular inflammation induces trigeminal pain, peripheral and central neuroinflammatory mechanisms

Pierre-Serge Launay , Elodie Reboussin , Hong Liang , Karima Kessal , David Godefroy et al.
Neurobiology of Disease, 2016, 88, pp.16-28. ⟨10.1016/j.nbd.2015.12.017⟩
Article dans une revue hal-01258703 v1
Image document

Bilateral neuroinflammatory processes in visual pathways induced by unilateral ocular hypertension in the rat

Anaïs Sapienza , Anne-Laure Raveu , Elodie Reboussin , Christophe Roubeix , Céline Boucher et al.
Journal of Neuroinflammation, 2016, 13 (1)
Article dans une revue hal-01945066 v1
Image document

Combined 3DISCO clearing method, retrograde tracer and ultramicroscopy to map corneal neurons in a whole adult mouse trigeminal ganglion

Pierre-Serge Launay , David Godefroy , Hanen Khabou , William Rostene , José-Alain Sahel et al.
Experimental Eye Research, 2015, 139, pp.136-143. ⟨10.1016/j.exer.2015.06.008⟩
Article dans une revue hal-01172713 v1
Image document

Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma

Christophe Roubeix , David Godefroy , Céline Mias , Anaïs Sapienza , Luisa Riancho et al.
Current Stem Cell Research & Therapy, 2015, 6 (1), pp.177. ⟨10.1186/s13287-015-0168-0⟩
Article dans une revue hal-01202543 v1

À l’intérieur du tissu cérébral Alzheimer avec la méthode CLARITY : plaques séniles, dégénérescences neurofibrillaires et axones en 3D

Kunie Ando , Laborde Quentin , David Godefroy , Benoit Delatour , Charles Duyckaerts
Morphologie, 2015, 99 (326), pp.96-97
Article dans une revue hal-01946787 v1

Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma

Christophe Roubeix , David Godefroy , Céline Mias , Anaïs Sapienza , Luisa Riancho et al.
Current Stem Cell Research & Therapy, 2015, 6 (1)
Article dans une revue hal-01945084 v1

Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D

Kunie Ando , Quentin Laborde , Adina Lazar , David Godefroy , Ihsen Youssef et al.
Acta Neuropathologica, 2014, 128 (3), pp.457-459. ⟨10.1007/s00401-014-1322-y⟩
Article dans une revue hal-01944638 v1
Image document

A Simple Method for 3D Analysis of Immunolabeled Axonal Tracts in a Transparent Nervous System

Morgane Belle , David Godefroy , Chloé Dominici , Céline Heitz-Marchaland , Pavol Zelina et al.
Cell Reports, 2014, 9 (4), pp.1191-1201. ⟨10.1016/j.celrep.2014.10.037⟩
Article dans une revue hal-01083957 v1

Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D

Kunie Ando , Quentin Laborde , Adina Lazar , David Godefroy , Ihsen Youssef et al.
Acta Neuropathologica, 2014, 128 (3), pp.457-459. ⟨10.1007/s00401-014-1322-y⟩
Article dans une revue hal-03572608 v1
Image document

A Simple Method for 3D Analysis of Immunolabeled Axonal Tracts in a Transparent Nervous System

Morgane Belle , David Godefroy , Chloé M Dominici , Céline Heitz-Marchaland , Pavol Zelina et al.
Cell Reports, 2014, 9 (4), pp.1191-1201
Article dans une revue hal-01944649 v1
Image document

Effects of Methylmercury Contained in a Diet Mimicking the Wayana Amerindians Contamination through Fish Consumption: Mercury Accumulation, Metallothionein Induction, Gene Expression Variations, and Role of the Chemokine CCL2

Jean-Paul Bourdineaud , Muriel N. Laclau , Régine Maury-Brachet , Patrice Gonzalez , Magalie Baudrimont et al.
International Journal of Molecular Sciences, 2012, 13 (6), pp.7710-7738
Article dans une revue hal-01945289 v1
Image document

CXCR3 Antagonism of SDF-1(5-67) Restores Trabecular Function and Prevents Retinal Neurodegeneration in a Rat Model of Ocular Hypertension

Alexandre Denoyer , David Godefroy , Isabelle Célérier , Julie Frugier , Julie Degardin et al.
PLoS ONE, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩
Article dans une revue hal-01944693 v1

Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro

Chloé Clouzeau , David Godefroy , Luisa Riancho , William Rostene , Christophe Baudouin et al.
Molecular Vision, 2012, 18, pp.851-863
Article dans une revue hal-01945322 v1

Blockade of the chemokine receptor CXCR3 lowers intraocular pressure and prevents retinal degeneration in an animal model of glaucoma

Alexandre Denoyer , Frugier Julie , David Godefroy , Julie Degardin , Francoise Brignole-Baudouin et al.
Acta Ophthalmologica Scandinavica -Supplement-, 2012, 90
Article dans une revue hal-01946808 v1
Image document

Effects of Methylmercury Contained in a Diet Mimicking the Wayana Amerindians Contamination through Fish Consumption: Mercury Accumulation, Metallothionein Induction, Gene Expression Variations, and Role of the Chemokine CCL2.

Jean-Paul Bourdineaud , Muriel Laclau , Régine Maury-Brachet , Patrice Gonzalez , Magalie Baudrimont et al.
International Journal of Molecular Sciences, 2012, 13 (6), pp.7710-38. ⟨10.3390/ijms13067710⟩
Article dans une revue hal-00749442 v1
Image document

The chemokine CCL2 protects against methylmercury neurotoxicity.

David Godefroy , Romain-Daniel Gosselin , Akira Yasutake , Masatake Fujimura , Christophe Combadière et al.
Review of Economic Dynamics, 2012, 125 (1), pp.209-18. ⟨10.1093/toxsci/kfr252⟩
Article dans une revue inserm-00630697 v1

Implication of CCR2 Chemokine Receptor in Cocaine-Induced Sensitization

Jean Marc Trocello , William Rostène , Stéphane Melik-Parsadaniantz , David Godefroy , Emmanuel Roze et al.
Journal of Molecular Neuroscience, 2011, 44 (3), pp.147-151
Article dans une revue hal-01945340 v1

Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system

William Rostène , Marc-André Dansereau , David Godefroy , Juliette van Steenwinckel , Annabelle Reaux-Le Goazigo et al.
Journal of Neurochemistry, 2011, 118 (5), pp.680-694
Article dans une revue hal-01944671 v1

NaCl-induced hyperosmotic stress as an in vitro dry eye model potentiated by synergic toxic effects of Benzalkonium chloride on conjunctival epithelial cells

Chloé Clouzeau , David Godefroy , Luisa Riancho , William Rostene , Christophe Baudouin et al.
Toxicology Letters, 2011, 205, pp.S155
Article dans une revue hal-01946821 v1

Chemokines and chemokine receptors: New actors in neuroendocrine regulations

William Rostène , Alice Guyon , Lara Kular , David Godefroy , Federica Barbieri et al.
Frontiers in Neuroendocrinology, 2011, 32 (1), pp.10-24
Article dans une revue hal-01944623 v1

CX3CL1 is involved in the ocular surface inflammation induced by benzalkonium chloride

Alexandre Denoyer , David Godefroy , Julie Frugier , Francoise Brignole-Baudouin , William Rostene et al.
Acta Ophthalmologica Scandinavica -Supplement-, 2010, 88
Article dans une revue hal-01946832 v1

Methylmercury exposure downregulates the expression of Racl and leads to neuritic degeneration and ultimately apoptosis in cerebrocortical neurons

Masatake Fujimura , Fusako Usuki , William Rostene , David Godefroy , Masumi Sawada et al.
NeuroToxicology, 2009, 30 (1), pp.16-22
Article dans une revue hal-01945199 v1

Whole body distribution of the regulatory peptide 26RFa in male and female mice

David Godefroy , Marie Picot , Mélodie Devère , Saloua Takhlidjt , Corentin Guillemot et al.
47th conference of the Society of Neuroendocrinology, Oct 2025, Lausanne ( CH), Switzerland
Poster de conférence hal-05326310 v1

Expression et localisation de deux neuropeptides de la famille des RF-amides, Kp10 et 26RFa, et leurs récepteurs dans le testicule murin au cours de la première vague de la spermatogenèse

Magali Basille-Dugay , Laura Moutard , Frédérique Bateux , David Godefroy , Saloua Takhlidjt et al.
Journée Normande de Recherche Biomédicale, Jun 2024, Rouen, France. 2024
Poster de conférence hal-05165636 v1

To Help You Make “Transparisation” an Effective Tool

Romina D’Angelo , Laurence Dubreil , David Godefroy , Chloé Chaumeton , Matthieu Simion et al.
Ecole thématique “Functional Microscopy for Biology” (MiFoBio), Nov 2023, Presqu’île de Giens, France
Poster de conférence hal-04917715 v1

Senescence of POMC Neurons Induced by SELENOT Deprivation Enhances Neurosecretory Activity

Cédric Jehan , Dorthe Cartier , Christine Bucharles , Philippe Chan , David Godefroy et al.
45ème Colloque de La Société de Neuroendocrinologie, Sep 2023, Rouen, France. 2023
Poster de conférence hal-05325973 v1

A Working Group to Help you Make « Transparisation » / Clearing an Effective Tool

Romina D’Angelo , Katia Belcram , Laurence Dubreil , Chloé Chaumeton , Matthieu Simion et al.
Alternative Models to Animal Testing - 1st GSO Workshop, May 2023, Toulouse - Hôtel de Région, France
Poster de conférence hal-04917388 v1

Interactions neurones-cellules de gliome dans les processus d'invasion de la substance blanche, dans un modèle préclinique de glioblastome

Quentin Lemercier , Laurence Desrues , David Godefroy , Alexis Lebon , Lucie Martin et al.
Cancéropôle Nord-Ouest, May 2023, Deauville, France. 2023
Poster de conférence hal-05168189 v1

Neuron-Glioma Interactions in White Matter Invasion in a Preclinical Model of Glioblastoma

Quentin Lemercier , Alexis Lebon , Laurence Desrues , David Godefroy , Lucie Martin et al.
Journée Normande de Recherche Biomédicale, Jun 2022, Rouen, France. 2022
Poster de conférence hal-05164773 v1

Tridimensional Analysis of Catecholaminergic Neuron Distribution in Selenot-Deficience Mice

David Godefroy , Ben Yamine Mallouki , Loubna Boukhzar , Emmanuelle Carpentier , Yves Tillet et al.
Journée Normande de Recherche Biomédicale, Jun 2022, Rouen, France. 2022
Poster de conférence hal-05164770 v1

To Help You Make “Transparisation” an Effective Tool

Laurence Dubreil , Katia Belcram , Cholé Chaumeton , Romina d'Angelo , David Godefroy et al.
JST RMUI, Nov 2022, Rennes, France
Poster de conférence hal-03922305 v1

Neuron-Glioma Interactions in White Matter Invasion, in a Preclinical Model of Glioblastoma

Quentin Lemercier , Laurence Desrues , David Godefroy , Alexis Lebon , Lucie Martin et al.
Congrès Annuel de l'ACOCEF, Jul 2022, Rouen, France. 2022
Poster de conférence hal-05164772 v1
Image document

A Working Group to Help You Make "Transparisation" an Effective Tool

Romina D’Angelo , Katia Belcram , Cholé Chaumeton , Laurence Dubreil , David Godefroy et al.
18èmes Journées Annuelles du Cancéropôle Grand Sud-Ouest, Nov 2022, La Grande Motte, France.
Poster de conférence hal-04919990 v1

Evidences of early astroglial reactivity associated with glioma invasion in a preclinical model of glioblastoma

Quentin Lemercier , Laurence Desrues , David Godefroy , Pierrick Gandolfo , Hélène Castel et al.
23th annual meeting of the LARC-Neuroscience network, Oct 2019, Nantes, France
Poster de conférence hal-02452583 v1

Le RNAscope® : une solution d'imagerie de l'ARN

Marie Picot , David Godefroy
Conférence IRIB, Feb 2024, Rouen, France
Communication dans un congrès hal-05163709 v1

Glucose Homeostasis and Energy Metabolism Are Impaired in Orexins Deficient Mice

Mélodie Devère , Saloua Takhlidjt , Jean-Luc Do Rego , Jean-Claude Do Rego , Alexandre Benani et al.
46. colloque de la Société de Neuroendocrinologie (SNE), Sep 2024, Nice, France
Communication dans un congrès hal-05163697 v1

Transparisation et imagerie 3D du sphéroide à l'organisme entier, chez l'animal et/ou le végétal

David Godefroy
ONIRIS, Oct 2024, Nantes, France
Communication dans un congrès hal-05163704 v1

The urotensin II receptor relays key neurobiological mechanisms in subarachnoid hemorrhage: Efficacy of pathway-targeted drugs on long-term brain deficits

Martin Pedard , Martine Dubois , Roxane Gruel , Laurence Desrues , David Godefroy et al.
Congrès annuel du GDR-GPCR, Oct 2019, Montpellier, France
Communication dans un congrès hal-02418166 v1

The urotensin II receptor relays key neurobiological mechanisms in subarachnoid hemorrhage: Efficacy of pathway-targeted drugs on early meningeal damages and long-term brain deficits

Martin Pedard , Martine Dubois , Roxane Gruel , Laurence Desrues , David Godefroy et al.
LARC-Neuroscience network, Oct 2019, Nantes, France
Communication dans un congrès hal-02418192 v1

Transparisation et imagerie des échantillons biologiques, quelle méthode? Quelle application?

Laurence Dubreil , Orestis Faklaris , Romina d'Angelo , Thomas Guilbert , David Godefroy
15ème assises Nationales des plateformes d'imagerie cellulaire du RTMFM, Plate-Forme Régionale de Recherche en Imagerie Cellulaire de Haute-Normandie (PRIMACEN). FRA., Mar 2018, Rouen, France
Communication dans un congrès hal-01869883 v1