Davy SINNAEVE

45
Documents

Publications

Publications

Deposit thumbnail

Fast Ultra‐Selective 1H‐15N 1D NMR Spectroscopy Unlocks Atom‐Resolved Dynamics of Low‐Complexity Protein Regions

Wiktor Adamski , Geraldine R Levy , François-Xavier Cantrelle , Davy Sinnaeve

Angewandte Chemie International Edition, 2026, pp.e19206. ⟨10.1002/anie.202519206⟩

Article dans une revue hal-05534270v1
Deposit thumbnail

Site-Specific Incorporation of Fluorinated Prolines into Proteins and their Impact on Neighbouring Residues

Carlos Elena-Real , Annika Urbanek , Amin Sagar , Priyesh Mohanty , Geraldine Levy et al.

Chemistry - A European Journal, In press, ⟨10.1002/chem.202403718⟩

Article dans une revue hal-04865645v1
Deposit thumbnail

Making 1H– 1H Couplings More Accessible and Accurate with Selective 2DJ NMR Experiments Aided by 13C Satellites

François-Xavier Cantrelle , Emmanuelle Boll , Davy Sinnaeve

Analytical Chemistry, 2024, 96 (18), pp.7056-7064. ⟨10.1021/acs.analchem.4c00315⟩

Article dans une revue hal-04733955v1
Deposit thumbnail

Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region

Alessia Lasorsa , Krishnendu Bera , Idir Malki , Elian Dupré , François-Xavier Cantrelle et al.

Biochemistry, 2023, 62 (11), pp.1631-1642. ⟨10.1021/acs.biochem.2c00717⟩

Article dans une revue hal-04140342v1
Deposit thumbnail

Obtaining Pure 1H NMR Spectra of Individual Pyranose and Furanose Anomers of Reducing Deoxyfluorinated Sugars

Gabija Poškaitė , David E Wheatley , Neil Wells , Bruno Linclau , Davy Sinnaeve

Journal of Organic Chemistry, 2023, 88 (19), pp.13908 - 13925. ⟨10.1021/acs.joc.3c01503⟩

Article dans une revue hal-04304362v1
Deposit thumbnail

The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity

Carlos A Elena-Real , Amin Sagar , Annika Urbanek , Matija Popovic , Anna Morató et al.

Nature Structural and Molecular Biology, 2023, 30 (3), pp.309 - 320. ⟨10.1038/s41594-023-00920-0⟩

Article dans une revue hal-04052774v1
Deposit thumbnail

Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools

Isabelle Landrieu , Elian Dupré , Davy Sinnaeve , Léa El Hajjar , Caroline Smet-Nocca

Frontiers in Chemistry, 2022, 10, pp.886382. ⟨10.3389/fchem.2022.886382⟩

Article dans une revue hal-03841022v1
Deposit thumbnail

Relating Conformational Equilibria to Conformer‐Specific Lipophilicities: New Opportunities in Drug Discovery

Bruno Linclau , Zhong Wang , Benjamin Jeffries , Jérôme Graton , Rodrigo Carbajo et al.

Angewandte Chemie International Edition, 2022, 61 (7), pp.e202114862. ⟨10.1002/anie.202114862⟩

Article dans une revue hal-03635530v1
Deposit thumbnail

Fluorine NMR study of proline-rich sequences using fluoroprolines

Davy Sinnaeve , Abir Ben Bouzayene , Emile Ottoy , Gert-Jan Hofman , Eva Erdmann et al.

Magnetic Resonance, 2021, 2 (2), pp.795-813. ⟨10.5194/mr-2-795-2021⟩

Article dans une revue hal-03430871v1
Deposit thumbnail

Expedited NMR Assignment of Small- to Medium-Sized Molecules with Improved HSQC−CLIP−COSY Experiments

Tamás Gyöngyösi , István Timári , Davy Sinnaeve , Burkhard Luy , Katalin E. Kövér

Analytical Chemistry, 2021, 93 (6), pp.3096-3102. ⟨10.1021/acs.analchem.0c04124⟩

Article dans une revue hal-03328594v1
Deposit thumbnail

Probing Long‐Range Anisotropic Interactions: a General and Sign‐Sensitive Strategy to Measure 1 H– 1 H Residual Dipolar Couplings as a Key Advance for Organic Structure Determination

Davy Sinnaeve , Julian Ilgen , Maria Enrica Di Pietro , Johann Primozic , Volker Schmidts et al.

Angewandte Chemie International Edition, 2020, 59 (13), pp.5316-5320. ⟨10.1002/anie.201915278⟩

Article dans une revue hal-02538220v1
Deposit thumbnail

Identification of the Molecular Determinants Involved in Antimicrobial Activity of Pseudodesmin A, a Cyclic Lipopeptide From the Viscosin Group

Matthias de Vleeschouwer , Tim van Kersavond , Yentl Verleysen , Davy Sinnaeve , Tom Coenye et al.

Frontiers in Microbiology, 2020, 11, pp.646. ⟨10.3389/fmicb.2020.00646⟩

Article dans une revue hal-03007409v1
Deposit thumbnail

Targeted delivery of adamantylated peptidoglycan immunomodulators in lipid nanocarriers: NMR shows that cargo fragments are available on the surface

Rosana Ribić , Mateja Manček-Keber , Fernando Chain , Davy Sinnaeve , José C Martins et al.

Journal of Physical Chemistry B, 2020, 124 (20), pp.4132-4145. ⟨10.1021/acs.jpcb.0c00029⟩

Article dans une revue hal-03009687v1
Deposit thumbnail

1H, 13C, and 15N chemical shift assignment of human PACSIN1/syndapin I SH3 domain in solution

Emmanuelle Boll , François-Xavier Cantrelle , Isabelle Landrieu , Matthieu Hirel , Davy Sinnaeve et al.

Biomolecular NMR Assignments, 2020, ⟨10.1007/s12104-020-09940-z⟩

Article dans une revue hal-02537946v1
Deposit thumbnail

Selective homonuclear 2D J-resolved spectroscopy

Davy Sinnaeve

eMagRes, 2020, 9 (4), pp.267-282. ⟨10.1002/9780470034590.emrstm1544⟩

Article dans une revue hal-03322837v1
Deposit thumbnail

Adamantane Containing Peptidoglycan Fragments Enhance RANTES and IL-6 Production in Lipopolysaccharide-Induced Macrophages

Mateja Manček-Keber , Rosana Ribić , Fernando Chain , Davy Sinnaeve , José C. Martins et al.

Molecules, 2020, 25 (16), pp.3707. ⟨10.3390/molecules25163707⟩

Article dans une revue hal-03008032v1

Conformation and Dynamics of the Cyclic Lipopeptide Viscosinamide at the Water-Lipid Interface

Niels Geudens , Benjamin Kovács , Davy Sinnaeve , Feyisara Eyiwumi Oni , Monica Höfte et al.

Molecules, 2019, 24 (12), pp.2257. ⟨10.3390/molecules24122257⟩

Article dans une revue hal-02538368v1
Deposit thumbnail

Fluorescent Pseudomonas and cyclic lipopeptide diversity in the rhizosphere of cocoyam ( Xanthosoma sagittifolium )

Feyisara Eyiwumi Oni , Niels Geudens , Olumide Owolabi Omoboye , Lien Bertier , Hoang Gia Khuong Hua et al.

Environmental Microbiology, 2019, 21 (3), pp.1019-1034. ⟨10.1111/1462-2920.14520⟩

Article dans une revue hal-02538659v1
Deposit thumbnail

Quantification of the electrostatic and covalent interaction between whey proteins and low methoxyl pectin using PFG-NMR diffusometry

Arima Diah Setiowati , Lien Vermeir , Lorenz de Neve , Ali Sedaghat Doost , Davy Sinnaeve et al.

Magnetic Resonance in Chemistry, 2019, Latest Developments and Applications of magnetic resonance in food science, 57 (9), pp.719-729. ⟨10.1002/mrc.4812⟩

Article dans une revue hal-02538690v1
Deposit thumbnail

Molecular Model for the Self-Assembly of the Cyclic Lipodepsipeptide Pseudodesmin A

Jean-Marc Crowet , Davy Sinnaeve , Krisztina Fehér , Yoann Laurin , Magali Deleu et al.

Journal of Physical Chemistry B, 2019, 123 (42), pp.8916-8922. ⟨10.1021/acs.jpcb.9b08035⟩

Article dans une revue hal-02538325v1

Synthesis and Conformational Properties of 3,4-Difluoro- l -prolines

Gert-Jan Hofman , Emile Ottoy , Mark E. Light , Bruno Kieffer , José C. Martins et al.

Journal of Organic Chemistry, 2019, 84 (6), pp.3100-3120. ⟨10.1021/acs.joc.8b02920⟩

Article dans une revue hal-02538639v1

Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J -Resolved NMR Spectroscopy

Davy Sinnaeve , Mickael Dinclaux , Edern Cahoreau , Pierre Millard , Jean-Charles Portais et al.

Analytical Chemistry, 2018, 90 (6), pp.4025-4031. ⟨10.1021/acs.analchem.7b05206⟩

Article dans une revue hal-02131883v1
Deposit thumbnail

Minimising conformational bias in fluoroprolines through vicinal difluorination

Gert-Jan Hofman , Emile Ottoy , Mark Light , Bruno Kieffer , Ilya Kuprov et al.

Chemical Communications, 2018, 54 (40), pp.5118-5121. ⟨10.1039/c8cc01493k⟩

Article dans une revue hal-03671903v1

Insight into peptide self-assembly from anisotropic rotational diffusion derived from 13C NMR relaxation

Davy Sinnaeve , Marc-André Delsuc , José Martins , Bruno Kieffer

Chemical Science, 2012, 3 (4), pp.1284. ⟨10.1039/C2SC01088G⟩

Article dans une revue hal-04984218v1

Intermolecular interaction studies using small volumes.

David Bourry , Davy Sinnaeve , Katelijne Gheysen , Bernd Fritzinger , Gianni Vandenborre et al.

Magnetic Resonance in Chemistry, 2011, 49 (1), pp.9-15. ⟨10.1002/mrc.2699⟩

Article dans une revue istex hal-00586937v1

A library of fluorinated prolines to study proline−rich motifs with 19F NMR

Emile Ottoy , Bruno Linclau , Bruno Kieffer , Ilya Kuprov , Davy Sinnaeve

Noncanonical amino acids (ncAAs): Tools for Biological and Biophysical Investigations, 2nd edition meeting, Oct 2024, Paris, France

Poster de conférence hal-05017059v1

Conformational ensemble analysis of flexible peptides using residual dipolar couplings

Elisa Norzagaray , Wiktor Adamski , Davy Sinnaeve

20th edition of the Young Belgian Magnetic Resonance Scientists symposium - YBMRS 2024, Nov 2024, Blankenberge, Belgium

Poster de conférence hal-05017160v1

A library of fluorinated prolines to study proline-rich motifs with 19F NMR

Emile Ottoy , Bruno Linclau , Bruno Kieffer , Ilya Kuprov , Davy Sinnaeve

The 20th European Magnetic Resonance Congress (EUROMAR 2024), Jun 2024, Bilbao, Spain

Poster de conférence hal-05017022v1

Applications of real-time band-selective pure shift in 1H-15N HSQC experiments for 15N-labelled proteins

Jorge Moreira , Alexander P. Golovanov , Gareth A Morris , Mathias J Nilsson , Peter Kiraly et al.

The 20th European Magnetic Resonance Congress (EUROMAR 2024), Jun 2024, Bilbao, Spain

Poster de conférence hal-05017134v1

Fast access to protein dynamics using Hartmann-Hahn edited 15N- 1H spectroscopy

Wiktor Adamski , François-Xavier Cantrelle , Davy Sinnaeve

The 20th European Magnetic Resonance Congress (EUROMAR 2024), Jun 2024, Bilbao, Spain

Poster de conférence hal-05017142v1

Molecular Dynamics with Orientational Constraints to investigate the conformational landscape of biomolecules

Wiktor Adamski , Xavier Hanoulle , Davy Sinnaeve

XIIIth International Conference — NMR: a tool for biology, May 2023, Paris, France

Poster de conférence hal-05017701v1

Molecular Dynamics with Orientational Constraints to investigate the conformational landscape of biomolecules

Wiktor Adamski , Xavier Hanoulle , Davy Sinnaeve

The 19th European Magnetic Resonance Congress (EUROMAR 2023), Jul 2023, Glasgow, United Kingdom

Poster de conférence hal-05017117v1

A general method for fully homodecoupled 1H-13C HSQC spectra

James R. D. Montgomery , Davy Sinnaeve

The 18th European Magnetic Resonance Congress (EUROMAR 2022), Jul 2022, Utrecht, Netherlands

Poster de conférence hal-05016941v1

A general method for fully homodecoupled 1H-13C HSQC spectra

Davy Sinnaeve

The 1st Virtual Conference of the GERM, Apr 2021, En ligne, France

Poster de conférence hal-05016934v1

A library of fluorinated prolines to study proline−rich motifs with 19F NMR

Davy Sinnaeve , Emile Ottoy , Bruno Linclau , Bruno Kieffer , Ilya Kuprov

Advanced Isotopic Labelling Methods for Integrated Structural Biology 2024, May 2024, Grenoble, France

Communication dans un congrès hal-05016924v1

Improved measurement and suppression of 1H−1H couplings aided by 13C nuclei

Davy Sinnaeve

12èmes Rencontres RMN-RPE-IRM, Le pôle RMN de l’Université de Lille, Jun 2024, Lille, France

Communication dans un congrès hal-05016882v1

Fast access to protein dynamics using ultra-selective 15N-1H spectroscopy

Wiktor Adamski , François-Xavier Cantrelle , Géraldine Levy , Davy Sinnaeve

20th edition of the Young Belgian Magnetic Resonance Scientists symposium - YBMRS 2024, Nov 2024, Blankenberge, Belgium

Communication dans un congrès hal-05017163v1

Improving accuracy and accessibility in ¹H-¹H coupling measurements by using ¹³C satellites

Davy Sinnaeve

The 19th European Magnetic Resonance Congress (EUROMAR 2023), Groupement Ampere, Jul 2023, Glasgow, United Kingdom

Communication dans un congrès hal-05016844v1

Conformational dynamics analysis of (macro)molecules from Residual Dipolar Couplings and Heteronuclear Spin Relaxation

Wiktor Adamski , Davy Sinnaeve

11es Rencontres RMN-RPE (Lille), Le pôle RMN de l’Université de Lille, Nov 2023, Villeneuve d'Ascq, France

Communication dans un congrès hal-05017167v1

Making good use of 13C to either measure or suppress 1H-1H couplings

Davy Sinnaeve

Réunion RMN Grand Bassin Parisien, Réseau RMN structurale dans le Bassin Parisien; Fr2950 CNRS Fédération RMN Solide Hauts Champs, Jan 2023, Paris, France

Communication dans un congrès hal-05016793v1

Premier spectromètre RMN 1,2 GHz français : quelles nouvelles possibilités pour l’analyse ?

Fabien Ferrage , Pierre Florian , Guy Lippens , Emmanuel Maes , Guido Pintacuda et al.

Réunion des utilisateurs RMN de Bruker France, Nov 2023, Lille, France

Communication dans un congrès hal-04470791v1

New ways to measure and suppress 1H-1H couplings in 1H-13C experiments

Davy Sinnaeve

43rd FGMR Annual Discussion Meeting, Division of Magnetic Resonance of the German Chemical society, Sep 2022, Karlsruhe, Germany

Communication dans un congrès hal-05016769v1