Déborah HELLE

20
Documents

Publications

Publications

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B3GALT6 mutations lead to compromised connective tissue biomechanics in Ehlers-Danlos syndrome

Roméo Milan Diana , Benjamin Jolivet , Jean-Baptiste Vincourt , Sébastien Hergalant , Grégory Francius et al.
JCI Insight, 2025, 10 (16), pp.e179474. ⟨10.1172/jci.insight.179474⟩
Article dans une revue hal-05234907 v1
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MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR

Sébastien Hergalant , Jean-Matthieu Casse , Abderrahim Oussalah , Rémi Houlgatte , Deborah Helle et al.
Frontiers in Oncology, 2023, 13, pp.1158773. ⟨10.3389/fonc.2023.1158773⟩
Article dans une revue hal-04176105 v1
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Characterization of an Innovative Biomaterial Derived From Human Wharton’s Jelly as a New Promising Coating for Tissue Engineering Applications

Adrien Fayon , Deborah Helle , Gregory Francius , Jean-Baptiste Vincourt , Véronique Regnault et al.
Frontiers in Bioengineering and Biotechnology, 2022, 10, pp.884069. ⟨10.3389/fbioe.2022.884069⟩
Article dans une revue hal-03753092 v1

Glucocorticoid Receptor Activation Restores Learning Memory by Modulating Hippocampal Plasticity in a Mouse Model of Brain Vitamin B12 Deficiency

Natacha Dreumont , Khalid Mimoun , Carine Pourié , Edward Quadros , Jean-Marc Alberto et al.
Molecular Neurobiology, 2020, 58 (3), pp.1024-1035. ⟨10.1007/s12035-020-02163-2⟩
Article dans une revue hal-03043614 v1
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N‐homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimer's disease and vascular dementia

Carine Bossenmeyer-Pourie , David A. Smith , Sylvain Lehmann , Vincent Deramecourt , Bernard Sablonnière et al.
Journal of Pathology, 2019, 248 (3), pp.291-303. ⟨10.1002/path.5254⟩
Article dans une revue hal-02389312 v1

Methyl Donor Deficiency during Gestation and Lactation in the Rat Affects the Expression of Neuropeptides and Related Receptors in the Hypothalamus

L Saber Cherif , P Pourié , A Geoffroy , A Julien , Deborah Helle et al.
International Journal of Molecular Sciences, 2019, 20 (20), pp.5097. ⟨10.3390/ijms20205097⟩
Article dans une revue hal-03049896 v1

Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid

Andréa Geoffroy , Lynda Saber-Cherif , Grégory Pourié , Deborah Helle , Rémy Umoret et al.
International Journal of Molecular Sciences, 2019, 20 (4), pp.973. ⟨10.3390/ijms20040973⟩
Article dans une revue hal-03049898 v1

Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia

Guillaume Gauchotte , Sébastien Hergalant , Charlène Vigouroux , Matthieu Casse , Rémi Houlgatte et al.
The Journal of pathology and bacteriology, 2017, 242 (4), pp.421 - 434. ⟨10.1002/path.4916⟩
Article dans une revue hal-01718786 v1

Late Maternal Folate Supplementation Rescues from Methyl Donor Deficiency-Associated Brain Defects by Restoring Let-7 and miR-34 Pathways

Andrea Geoffroy , Racha Kerek , Grégory Pourié , Deborah Helle , Jean-Louis Guéant et al.
Molecular Neurobiology, 2017, 54 (7), pp.5017-5033. ⟨10.1007/s12035-016-0035-8⟩
Article dans une revue hal-01666792 v1

Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor- coactivator-1 -dependent vitamin D receptor pathway

E. Feigerlova , L. Demarquet , H. Melhem , R. Ghemrawi , S.-F. Battaglia-Hsu et al.
FASEB Journal, 2016, 30 (10), pp.3598 - 3612. ⟨10.1096/fj.201600332R⟩
Article dans une revue hal-01666802 v1

Folate- and vitamin B-12-deficient diet during gestation and lactation alters cerebellar synapsin expression via impaired influence of estrogen nuclear receptor alpha

Grégory Pourié , Nicolas Martin , Carine Bossenmeyer-Pourie , Nassila Akchiche , Rosa Maria Gueant-Rodriguez et al.
FASEB Journal, 2015, 29 (9), pp.3713-3725. ⟨10.1096/fj.14-264267⟩
Article dans une revue hal-01217630 v1

Early methyl donor deficiency may induce persistent brain defects by reducing Stat3 signaling targeted by miR-124

R Kerek , G. Geoffroy , A Bison , N Martin , N Akchiche et al.
Cell Death and Disease, 2013, 4 (8), pp.e755 - e755. ⟨10.1038/cddis.2013.278⟩
Article dans une revue hal-01701266 v1

Early methyl donor deficiency produces severe gastritis in mothers and offspring through N -homocysteinylation of cytoskeleton proteins, cellular stress, and inflammation

Carine Bossenmeyer-Pourié , Grégory Pourié , Violette Koziel , Deborah Helle , Elise Jeannesson et al.
FASEB Journal, 2013, 27 (6), pp.2185 - 2197. ⟨10.1096/fj.12-224642⟩
Article dans une revue hal-01701775 v1

Su1754 Persistence of the Gastric Mucosa Inflammation After Fetal and Early Post-Natal Exposition to Methyl Donor Deficiency in the Rat

Carine Pourie , Jean-Luc Daval , Grégory Pourié , Catherine Tomasetto , Déborah Helle et al.
Gastroenterology, 2012, 142 (5), pp.S-495 - S-496. ⟨10.1016/S0016-5085(12)61896-4⟩
Article dans une revue hal-01718806 v1

Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells.

Nassila Akchiche , Carine Bossenmeyer-Pourié , Racha Kerek , Nicolas Martin , Grégory Pourié et al.
FASEB Journal, 2012, 26 (10), pp.3980-92. ⟨10.1096/fj.12-205757⟩
Article dans une revue hal-00759122 v1