Delphine Fradin

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Publications

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Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer

Maureen Labbé , Manon Chang , Benjamin Saintpierre , Franck Letourneur , Laurence de Beaurepaire et al.
Cell Death and Disease, 2024, 15 (10), pp.751. ⟨10.1038/s41419-024-07133-3⟩
Article dans une revue inserm-04770147 v1

Oncolytic viruses alter the biogenesis of tumor extracellular vesicles and influence their immunogenicity

Ugo Hirigoyen , Coraly Guilbaud , Morgane Krejbich , Morgane Fouet , Judith Fresquet et al.
Molecular Therapy: Oncology, 2024, 32 (4), pp.200887. ⟨10.1016/j.omton.2024.200887⟩
Article dans une revue inserm-04745858 v1
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Use of non-small cell lung cancer multicellular tumor spheroids to study the impact of chemotherapy

Pauline Hulo , Sophie Deshayes , Judith Fresquet , Anne-Laure Chéné , Stéphanie Blandin et al.
Respiratory Research, 2024, 25 (1), pp.156. ⟨10.1186/s12931-024-02791-5⟩
Article dans une revue inserm-04537685 v1
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Interplay between oncolytic measles virus, macrophages and cancer cells induces a proinflammatory tumor microenvironment

Camille Chatelain , Laurine Berland , Marion Grard , Nicolas Jouand , Judith Fresquet et al.
OncoImmunology, 2024, 13 (1), pp.2377830. ⟨10.1080/2162402x.2024.2377830⟩
Article dans une revue inserm-04652311 v1
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TP53 mutations correlate with the non‐coding RNA content of small extracellular vesicles in melanoma

Maureen Labbé , Estelle Menoret , Franck Letourneur , Benjamin Saint‐pierre , Laurence de Beaurepaire et al.
Journal of Extracellular Biology, 2023, 2, ⟨10.1002/jex2.105⟩
Article dans une revue hal-04198069 v1
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DNA methylation dynamics during pregnancy

Delphine Fradin , Jorg Tost , Florence Busato , Clémence Mille , Fanny Lachaux et al.
Frontiers in Cell and Developmental Biology, 2023, 11, pp.1185311. ⟨10.3389/fcell.2023.1185311⟩
Article dans une revue inserm-04164740 v1

Therapeutic strategies for non-small cell lung cancer: Experimental models and emerging biomarkers to monitor drug efficacies

Clara Bourreau , Lucas Treps , Sébastien Faure , Delphine Fradin , Nicolas Clere
Pharmacology and Therapeutics, 2023, pp.108347. ⟨10.1016/j.pharmthera.2023.108347⟩
Article dans une revue hal-03944679 v1
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Oncolytic attenuated measles virus encoding NY-ESO-1 induces HLA I and II presentation of this tumor antigen by melanoma and dendritic cells

Marion Grard , Mohamed Idjellidaine , Atousa Arbabian , Camille Chatelain , Laurine Berland et al.
Cancer Immunology, Immunotherapy, 2023, 72 (10), pp.3309-3322. ⟨10.1007/s00262-023-03486-4⟩
Article dans une revue inserm-04581137 v1
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The DCMU Herbicide Shapes T-cell Functions By Modulating Micro-RNA Expression Profiles

Pierre Autin , Sophie Deshayes , Juliette Lea , Nicolas Boisgerault , Emilie Dupré et al.
Frontiers in Immunology, 2022, 13, pp.925241. ⟨10.3389/fimmu.2022.925241⟩
Article dans une revue inserm-03752032 v1

Monocyte Signature Associated with Herpes Simplex Virus Reactivation and Neurological Recovery after Brain Injury

Tanguy Chaumette , Raphael Cinotti , Alice Mollé , Pierre Solomon , Louise Castain et al.
American Journal of Respiratory and Critical Care Medicine, 2022, 206 (3), pp.295-310. ⟨10.1164/rccm.202110-2324OC⟩
Article dans une revue hal-04521801 v1
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Interaction Between Modern Radiotherapy and Immunotherapy for Metastatic Prostate Cancer

Luc Ollivier , Maureen Labbé , Delphine Fradin , Vincent Potiron , Stéphane Supiot
Frontiers in Oncology, 2021, 11, pp.744679. ⟨10.3389/fonc.2021.744679⟩
Article dans une revue inserm-03369787 v1
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Combinaison radiothérapie-immunothérapie en cancérologie génito-urinaire

L. Ollivier , V. Guimas , E. Rio , L. Vaugier , I. Masson et al.
Cancer/Radiothérapie, 2021, 25 (6-7), pp.565-569. ⟨10.1016/j.canrad.2021.06.033⟩
Article dans une revue inserm-03540455 v1
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Transcriptomic features of tumour- infiltrating CD4 low CD8 high double positive αβ T cells in melanoma

Tiphaine Parrot , Romain Oger , Mathilde Allard , Juliette Desfrançois , Diane Raingeard de La Blétìère et al.
Scientific Reports, 2020, 10 (1), pp.5900. ⟨10.1038/s41598-020-62664-x⟩
Article dans une revue inserm-02534481 v1
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Critical Roles of Tumor Extracellular Vesicles in the Microenvironment of Thoracic Cancers

Lyna Kara-Terki , Lucas Treps , Christophe Blanquart , Delphine Fradin
International Journal of Molecular Sciences, 2020, 21 (17), pp.6024. ⟨10.3390/ijms21176024⟩
Article dans une revue inserm-02946311 v1

Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus

Tiphaine Delaunay , Carole Achard , Nicolas Boisgerault , Marion Grard , Tacien Petithomme et al.
Journal of Thoracic Oncology, 2020, 15 (5), pp.827-842. ⟨10.1016/j.jtho.2019.12.128⟩
Article dans une revue hal-04275491 v1
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microRNAs identified in prostate cancer: Correlative studies on response to ionizing radiation

Maureen Labbé , Christianne Hoey , Jessica Ray , Vincent Potiron , Stephane Supiot et al.
Molecular Cancer, 2020, 19, pp.63. ⟨10.1186/s12943-020-01186-6⟩
Article dans une revue inserm-02515300 v1
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Increased antitumor efficacy of PD-1- deficient melanoma-specific human lymphocytes

Lucine Marotte , Sylvain Simon , Virginie Vignard , Emilie Dupré , Malika Gantier et al.
Journal for Immunotherapy of Cancer, 2020, 8, pp.e000311. ⟨10.1136/jitc-2019-000311⟩
Article dans une revue inserm-02481085 v1
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Regulatory T Cell Stability and Migration Are Dependent on mTOR

Romain Vallion , Jordane Divoux , Salomé Glauzy , Emilie Ronin , Yannis Lombardi et al.
Journal of Immunology, 2020, 205 (7), pp.1799-1809. ⟨10.4049/jimmunol.1901480⟩
Article dans une revue inserm-02946304 v1
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Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus

Tiphaine Delaunay , Carole Achard , Nicolas Boisgerault , Marion Grard , Tacien Petithomme et al.
Journal of Thoracic Oncology, 2020, S1556-0864(20)30019-8, Epub ahead of print. ⟨10.1016/j.jtho.2019.12.128⟩
Article dans une revue inserm-02447160 v1
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MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma

Virginie Vignard , Maureen Labbé , Nadège Marec , Gwennan André-Grégoire , Nicolas Jouand et al.
Cancer Immunology Research, 2019, canimm.0522.2019, Epub ahead of print. ⟨10.1158/2326-6066.CIR-19-0522⟩
Article dans une revue inserm-02426329 v1
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Viral and tumor antigen-specific CD8 T-cell responses in Merkel cell carcinoma

Mahtab Samimi , Houssem Benlalam , Pascal Aumond , Pauline Gaboriaud , Delphine Fradin et al.
Cellular Immunology, 2019, 344, 8 p. ⟨10.1016/j.cellimm.2019.103961⟩
Article dans une revue inserm-02284748 v1
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Epigenetic Drugs for Cancer and microRNAs: A Focus on Histone Deacetylase Inhibitors

Pierre Autin , Christophe Blanquart , Delphine Fradin
Cancers, 2019, 11 (10), pp.1530. ⟨10.3390/cancers11101530⟩
Article dans une revue inserm-02315396 v1
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Fetal growth is associated with the CpG methylation of the P2 promoter of the IGF1 gene

Catherine Le Stunff , Anne-Laure Castell , Nicolas Todd , Clémence Mille , Marie-Pierre Belot et al.
Clinical Epigenetics, 2018, 10, pp.57. ⟨10.1186/s13148-018-0489-9⟩
Article dans une revue inserm-01782203 v1
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Non-Coding RNAs in Cutaneous Melanoma Development, Progression and Dissemination

Virginie Vignard , Delphine Fradin
OBM Genetics, 2018, 2 (2), pp.1 - 1. ⟨10.21926/obm.genet.1802020⟩
Article dans une revue inserm-01804848 v1
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Correction to: Fetal growth is associated with CpG methylation in the P2 promoter of the IGF1 gene

Catherine Le Stunff , Anne-Laure Castell , Nicolas Todd , Clémence Mille , Marie-Pierre Belot et al.
Clinical Epigenetics, 2018, 10 (1), pp.74. ⟨10.1186/s13148-018-0506-z⟩
Article dans une revue hal-04961045 v1
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Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children

Delphine Fradin , Pierre-Yves Boëlle , Marie-Pierre Belot , Fanny Lachaux , Jorg Tost et al.
Scientific Reports, 2017, 7, pp.46311. ⟨10.1038/srep46311⟩
Article dans une revue hal-01516806 v1
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Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children

Delphine Fradin , Pierre-Yves Boëlle , Marie-Pierre Belot , Fanny Lachaux , Jörg Tost et al.
Scientific Reports, 2017, 7 (1), pp.46311. ⟨10.1038/srep46311⟩
Article dans une revue inserm-02320512 v1
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The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature

Danny Ben-Avraham , Diddahally Govindaraju , Temuri Budagov , Delphine Fradin , Peter Durda et al.
Science Advances , 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩
Article dans une revue inserm-02320509 v1
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Role of DNA methylation at the placental RTL1 gene locus in type 1 diabetes

Marie-Pierre Belot , Kambiz Nadéri , Clémence Mille , Pierre-Yves Boëlle , Alexandra Benachi et al.
Pediatric Diabetes, 2017, 18 (3), pp.178-187. ⟨10.1111/pedi.12387⟩
Article dans une revue inserm-02320514 v1
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The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness

M Ouni , M P Belot , A. L. Castell , Delphine Fradin , P Bougnères
Pharmacogenomics Journal, 2016, 16, pp.102-106. ⟨10.1038/tpj.2015.26⟩
Article dans une revue hal-02329906 v1
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A lineage-specific methylation pattern controls the transcription of the polycistronic mRNA coding MELOE melanoma antigens

Benjamin Chalopin , Laetitia Florenceau , Delphine Fradin , Nathalie Labarrière , Agnès Moreau-Aubry
Melanoma Research, 2015, ⟨10.1097/CMR.0000000000000167⟩
Article dans une revue inserm-01280880 v1
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The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth

Meriem Ouni , Marie Pierre Belot , Anne-Laure Castell , Delphine Fradin , Pierre Bougneres
Clinical Epigenetics, 2015, 7, pp.22. ⟨10.1186/s13148-015-0062-8⟩
Article dans une revue hal-02459502 v1
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β cells keep bad epigenetic memories of palmitate

Delphine Fradin , Pierre Bougnères
BMC Medicine, 2014, 12 (1), ⟨10.1186/1741-7015-12-104⟩
Article dans une revue hal-02329943 v1
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Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia

Fabiola Tros , Aline Meirhaeghe , Samy Hadjadj , Philippe Amouyel , Pierre Bougnères et al.
Physiological Reports, 2014, 2, ⟨10.14814/phy2.12076⟩
Article dans une revue inserm-02459029 v1
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CpG Methylation Changes within the IL2RA Promoter in Type 1 Diabetes of Childhood Onset

Marie-Pierre Belot , Delphine Fradin , Nga Mai , Sophie Le Fur , Diana Zelenika et al.
PLoS ONE, 2013, 8 (7), pp.e68093. ⟨10.1371/journal.pone.0068093⟩
Article dans une revue hal-02329956 v1
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Association of the CpG Methylation Pattern of the Proximal Insulin Gene Promoter with Type 1 Diabetes

Delphine Fradin , Sophie Le Fur , Clémence Mille , Nadia Naoui , Chris Groves et al.
PLoS ONE, 2012, 7 (5), pp.e36278. ⟨10.1371/journal.pone.0036278⟩
Article dans une revue hal-02329970 v1
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XPG and XPF Endonucleases Trigger Chromatin Looping and DNA Demethylation for Accurate Expression of Activated Genes

Nicolas Le may , Delphine Fradin , Izarn Iltis , Pierre Bougneres , Jean Marc Egly
Molecular Cell, 2012, 47 (4), pp.622-632. ⟨10.1016/j.molcel.2012.05.050⟩
Article dans une revue hal-02329959 v1
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T2DM: Why Epigenetics?

Delphine Fradin , Pierre Bougneres
Journal of Nutrition and Metabolism, 2011, 2011, pp.1-17. ⟨10.1155/2011/647514⟩
Article dans une revue hal-02329973 v1
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Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index

Delphine Fradin , Rafael A Irizarry , Martin J Aryee , Peter Murakami , Thor Aspelund et al.
Science Translational Medicine, 2010, 2 (49), pp.49ra67-49ra67. ⟨10.1126/scitranslmed.3001262⟩
Article dans une revue hal-02329984 v1
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Parent-Of-Origin Effects in Autism Identified through Genome-Wide Linkage Analysis of 16,000 SNPs

Delphine Fradin , Keely Cheslack-Postava , Christine Ladd-Acosta , Craig Newschaffer , Aravinda Chakravarti et al.
PLoS ONE, 2010, 5 (9), pp.e12513. ⟨10.1371/journal.pone.0012513⟩
Article dans une revue hal-02329988 v1
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Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study

Delphine Fradin , M Daniele Fallin
BMC Proceedings, 2009, 3 (S7), ⟨10.1186/1753-6561-3-S7-S113⟩
Article dans une revue hal-02329993 v1
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Three Common Variants of LEP, NPY1R and GPR54 Show No Association with Age at Menarche

Anya Rothenbuhler , Chantal Lotton , Delphine Fradin
Hormone Research in Paediatrics, 2009, 71 (6), pp.331-335. ⟨10.1159/000223417⟩
Article dans une revue hal-02329997 v1
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Three Common Intronic Variants in the Maternal and Fetal Thiamine Pyrophosphokinase Gene (TPK1) are Associated with Birth Weight

Delphine Fradin , Pierre Bougneres
Annals of Human Genetics, 2007, ⟨10.1111/j.1469-1809.2007.00348.x⟩
Article dans une revue hal-02459482 v1
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Non-Mendelian' genetics of fetal growth

Delphine Fradin , Pascal Boileau , Jacques Lepercq , Pierre Bougneres
Journal of Endocrinological Investigation, 2006, 29 (Supp 1), pp.11-15
Article dans une revue hal-02459429 v1

ExomiR : Etude des microARNs des exosomes tumoraux

Delphine Fradin
13ème journées du Cancéropole Grand Ouest, Jul 2019, Tours, France
Communication dans un congrès hal-02459683 v1

INTERNALISATION DES EXOSOMES DE MELANOME PAR LES LYMPHOCYTES T CD8+ ET IMPACT SUR LEURS FONCTIONS : APPORT DU CYTOMETRE IMAGEUR

Delphine Fradin , Nicolas Jouand
Journée Imagerie fonctionnelle pré-clinique, Jun 2019, Rennes, France
Communication dans un congrès hal-02459677 v1
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L'EPIGENETIQUE, C'EST QUOI ?

Delphine Fradin
22ème journées de Médecine Foetale, Mar 2017, Nice, France
Communication dans un congrès hal-02459664 v1

EXPLORATION DES FONCTIONS IMMUNOSUPPRESSIVES DES ARN NON CODANTS CONTENUS DANS LES EXOSOMES DU MÉLANOME

Delphine Fradin
3ème journées RepiCGO, Dec 2016, Brest, France
Communication dans un congrès hal-02459657 v1

Influence de l'hyperglycémie sur la méthylation de l'ADN

Delphine Fradin
Automnales du GRRC, Nov 2015, Pornichet, France
Communication dans un congrès hal-02459651 v1

EVOLUTION DES MARQUES ÉPIGÉNÉTIQUES AU COURS DE LA VIE

Delphine Fradin
ADELF-EPITER, Sep 2014, Nice, France
Communication dans un congrès hal-02459594 v1

GÉNÉTIQUE ET ÉPIGÉNÉTIQUE DU COMPORTEMENT SOCIAL

Delphine Fradin
Journées de l'Ecole Doctorale Pierre Louis de Santé Publique, Oct 2012, Saint Malo, France
Communication dans un congrès hal-02459610 v1

EPIGÉNÉTIQUE ET HYPERGLYCÉMIE : RÔLE DE LA MÉTHYLATION DANS LA RÉTINOPATHIE DIABÉTIQUE

Delphine Fradin
4e congrès annuel du CORDDIM, Sep 2012, Paris, France
Communication dans un congrès hal-02459620 v1

Aging and DNA methylation

Delphine Fradin
Seventh Annual Grantee Meeting of Centers of Excellence in Genomic Science, Oct 2009, Huntsville, United States
Communication dans un congrès hal-02459631 v1

INFLUENCE OF CONTROL SELECTION IN GENOME-WIDE ASSOCIATION STUDY: THE EXAMPLE OF DIABETES IN THE FRAMIGHAM HEART STUDY.

Delphine Fradin
Genetic Analysis Workshop 16, Sep 2008, Saint Louis, United States
Communication dans un congrès hal-02459645 v1