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Delphine Fradin

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TP53 mutations correlate with the non‐coding RNA content of small extracellular vesicles in melanoma

Maureen Labbé , Estelle Menoret , Franck Letourneur , Benjamin Saint‐pierre , Laurence de Beaurepaire
Journal of Extracellular Biology, 2023, 2, ⟨10.1002/jex2.105⟩
Journal articles hal-04198069v1
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DNA methylation dynamics during pregnancy

Delphine Fradin , Jorg Tost , Florence Busato , Clémence Mille , Fanny Lachaux
Frontiers in Cell and Developmental Biology, 2023, 11, pp.1185311. ⟨10.3389/fcell.2023.1185311⟩
Journal articles inserm-04164740v1
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Combinaison radiothérapie-immunothérapie en cancérologie génito-urinaire

L. Ollivier , V. Guimas , E. Rio , L. Vaugier , I. Masson
Cancer/Radiothérapie, 2021, 25 (6-7), pp.565-569. ⟨10.1016/j.canrad.2021.06.033⟩
Journal articles inserm-03540455v1
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Interaction Between Modern Radiotherapy and Immunotherapy for Metastatic Prostate Cancer

Luc Ollivier , Maureen Labbé , Delphine Fradin , Vincent Potiron , Stéphane Supiot
Frontiers in Oncology, 2021, 11, pp.744679. ⟨10.3389/fonc.2021.744679⟩
Journal articles inserm-03369787v1
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Increased antitumor efficacy of PD-1- deficient melanoma-specific human lymphocytes

Lucine Marotte , Sylvain Simon , Virginie Vignard , Emilie Dupré , Malika Gantier
Journal for Immunotherapy of Cancer, 2020, 8, pp.e000311. ⟨10.1136/jitc-2019-000311⟩
Journal articles inserm-02481085v1
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microRNAs identified in prostate cancer: Correlative studies on response to ionizing radiation

Maureen Labbé , Christianne Hoey , Jessica Ray , Vincent Potiron , Stephane Supiot
Molecular Cancer, 2020, 19, pp.63. ⟨10.1186/s12943-020-01186-6⟩
Journal articles inserm-02515300v1
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Regulatory T Cell Stability and Migration Are Dependent on mTOR

Romain Vallion , Jordane Divoux , Salomé Glauzy , Emilie Ronin , Yannis Lombardi
Journal of Immunology, 2020, 205 (7), pp.1799-1809. ⟨10.4049/jimmunol.1901480⟩
Journal articles inserm-02946304v1
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Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus

Tiphaine Delaunay , Carole Achard , Nicolas Boisgerault , Marion Grard , Tacien Petithomme
Journal of Thoracic Oncology, 2020, S1556-0864(20)30019-8, Epub ahead of print. ⟨10.1016/j.jtho.2019.12.128⟩
Journal articles inserm-02447160v1
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Critical Roles of Tumor Extracellular Vesicles in the Microenvironment of Thoracic Cancers

Lyna Kara-Terki , Lucas Treps , Christophe Blanquart , Delphine Fradin
International Journal of Molecular Sciences, 2020, 21 (17), pp.6024. ⟨10.3390/ijms21176024⟩
Journal articles inserm-02946311v1
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Transcriptomic features of tumour- infiltrating CD4 low CD8 high double positive αβ T cells in melanoma

Tiphaine Parrot , Romain Oger , Mathilde Allard , Juliette Desfrançois , Diane Raingeard de La Blétìère
Scientific Reports, 2020, 10 (1), pp.5900. ⟨10.1038/s41598-020-62664-x⟩
Journal articles inserm-02534481v1
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Epigenetic Drugs for Cancer and microRNAs: A Focus on Histone Deacetylase Inhibitors

Pierre Autin , Christophe Blanquart , Delphine Fradin
Cancers, 2019, 11 (10), pp.1530. ⟨10.3390/cancers11101530⟩
Journal articles inserm-02315396v1
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Viral and tumor antigen-specific CD8 T-cell responses in Merkel cell carcinoma

Mahtab Samimi , Houssem Benlalam , Pascal Aumond , Pauline Gaboriaud , Delphine Fradin
Cellular Immunology, 2019, 344, 8 p. ⟨10.1016/j.cellimm.2019.103961⟩
Journal articles inserm-02284748v1
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MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma

Virginie Vignard , Maureen Labbé , Nadège Marec , Gwennan André-Grégoire , Nicolas Jouand
Cancer Immunology Research, 2019, canimm.0522.2019, Epub ahead of print. ⟨10.1158/2326-6066.CIR-19-0522⟩
Journal articles inserm-02426329v1
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Non-Coding RNAs in Cutaneous Melanoma Development, Progression and Dissemination

Virginie Vignard , Delphine Fradin
OBM Genetics, 2018, 2 (2), pp.1 - 1. ⟨10.21926/obm.genet.1802020⟩
Journal articles inserm-01804848v1
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Fetal growth is associated with the CpG methylation of the P2 promoter of the IGF1 gene

Catherine Le Stunff , Anne-Laure Castell , Nicolas Todd , Clémence Mille , Marie-Pierre Belot
Clinical Epigenetics, 2018, 10, pp.57. ⟨10.1186/s13148-018-0489-9⟩
Journal articles inserm-01782203v1
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Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children

Delphine Fradin , Pierre-Yves Boëlle , Marie-Pierre Belot , Fanny Lachaux , Jorg Tost
Scientific Reports, 2017, 7, pp.46311. ⟨10.1038/srep46311⟩
Journal articles hal-01516806v1
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Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children

Delphine Fradin , Pierre-Yves Boëlle , Marie-Pierre Belot , Fanny Lachaux , Jörg Tost
Scientific Reports, 2017, 7 (1), pp.46311. ⟨10.1038/srep46311⟩
Journal articles inserm-02320512v1
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The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature

Danny Ben-Avraham , Diddahally Govindaraju , Temuri Budagov , Delphine Fradin , Peter Durda
Science Advances , 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩
Journal articles inserm-02320509v1
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Role of DNA methylation at the placental RTL1 gene locus in type 1 diabetes

Marie-Pierre Belot , Kambiz Nadéri , Clémence Mille , Pierre-Yves Boëlle , Alexandra Benachi
Pediatric Diabetes, 2017, 18 (3), pp.178-187. ⟨10.1111/pedi.12387⟩
Journal articles inserm-02320514v1
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The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness

M Ouni , M P Belot , A. L. Castell , Delphine Fradin , P Bougnères
Pharmacogenomics Journal, 2016, 16, pp.102-106. ⟨10.1038/tpj.2015.26⟩
Journal articles hal-02329906v1
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A lineage-specific methylation pattern controls the transcription of the polycistronic mRNA coding MELOE melanoma antigens

Benjamin Chalopin , Laetitia Florenceau , Delphine Fradin , Nathalie Labarrière , Agnès Moreau-Aubry
Melanoma Research, 2015, ⟨10.1097/CMR.0000000000000167⟩
Journal articles inserm-01280880v1
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The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth

Meriem Ouni , Marie Pierre Belot , Anne-Laure Castell , Delphine Fradin , Pierre Bougneres
Clinical Epigenetics, 2015, 7, pp.22. ⟨10.1186/s13148-015-0062-8⟩
Journal articles hal-02459502v1
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β cells keep bad epigenetic memories of palmitate

Delphine Fradin , Pierre Bougnères
BMC Medicine, 2014, 12 (1), ⟨10.1186/1741-7015-12-104⟩
Journal articles hal-02329943v1
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Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia

Fabiola Tros , Aline Meirhaeghe , Samy Hadjadj , Philippe Amouyel , Pierre Bougnères
Physiological Reports, 2014, 2, ⟨10.14814/phy2.12076⟩
Journal articles inserm-02459029v1
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CpG Methylation Changes within the IL2RA Promoter in Type 1 Diabetes of Childhood Onset

Marie-Pierre Belot , Delphine Fradin , Nga Mai , Sophie Le Fur , Diana Zelenika
PLoS ONE, 2013, 8 (7), pp.e68093. ⟨10.1371/journal.pone.0068093⟩
Journal articles hal-02329956v1
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Association of the CpG Methylation Pattern of the Proximal Insulin Gene Promoter with Type 1 Diabetes

Delphine Fradin , Sophie Le Fur , Clémence Mille , Nadia Naoui , Chris Groves
PLoS ONE, 2012, 7 (5), pp.e36278. ⟨10.1371/journal.pone.0036278⟩
Journal articles hal-02329970v1
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XPG and XPF Endonucleases Trigger Chromatin Looping and DNA Demethylation for Accurate Expression of Activated Genes

Nicolas Le may , Delphine Fradin , Izarn Iltis , Pierre Bougneres , Jean Marc Egly
Molecular Cell, 2012, 47 (4), pp.622-632. ⟨10.1016/j.molcel.2012.05.050⟩
Journal articles hal-02329959v1
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T2DM: Why Epigenetics?

Delphine Fradin , Pierre Bougneres
Journal of Nutrition and Metabolism, 2011, 2011, pp.1-17. ⟨10.1155/2011/647514⟩
Journal articles hal-02329973v1
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Parent-Of-Origin Effects in Autism Identified through Genome-Wide Linkage Analysis of 16,000 SNPs

Delphine Fradin , Keely Cheslack-Postava , Christine Ladd-Acosta , Craig Newschaffer , Aravinda Chakravarti
PLoS ONE, 2010, 5 (9), pp.e12513. ⟨10.1371/journal.pone.0012513⟩
Journal articles hal-02329988v1
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Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index

Delphine Fradin , Rafael A Irizarry , Martin J Aryee , Peter Murakami , Thor Aspelund
Science Translational Medicine, 2010, 2 (49), pp.49ra67-49ra67. ⟨10.1126/scitranslmed.3001262⟩
Journal articles hal-02329984v1
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Three Common Variants of LEP, NPY1R and GPR54 Show No Association with Age at Menarche

Anya Rothenbuhler , Chantal Lotton , Delphine Fradin
Hormone Research in Paediatrics, 2009, 71 (6), pp.331-335. ⟨10.1159/000223417⟩
Journal articles hal-02329997v1
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Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study

Delphine Fradin , M Daniele Fallin
BMC Proceedings, 2009, 3 (S7), ⟨10.1186/1753-6561-3-S7-S113⟩
Journal articles hal-02329993v1
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Three Common Intronic Variants in the Maternal and Fetal Thiamine Pyrophosphokinase Gene (TPK1) are Associated with Birth Weight

Delphine Fradin , Pierre Bougneres
Annals of Human Genetics, 2007, ⟨10.1111/j.1469-1809.2007.00348.x⟩
Journal articles hal-02459482v1
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'Non-Mendelian' genetics of fetal growth

Delphine Fradin , Pascal Boileau , Jacques Lepercq , Pierre Bougneres
Journal of Endocrinological Investigation, 2006, 29 (Supp 1), pp.11-15
Journal articles hal-02459429v1

INTERNALISATION DES EXOSOMES DE MELANOME PAR LES LYMPHOCYTES T CD8+ ET IMPACT SUR LEURS FONCTIONS : APPORT DU CYTOMETRE IMAGEUR

Delphine Fradin , Nicolas Jouand
Journée Imagerie fonctionnelle pré-clinique, Jun 2019, Rennes, France
Conference papers hal-02459677v1

ExomiR : Etude des microARNs des exosomes tumoraux

Delphine Fradin
13ème journées du Cancéropole Grand Ouest, Jul 2019, Tours, France
Conference papers hal-02459683v1
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L'EPIGENETIQUE, C'EST QUOI ?

Delphine Fradin
22ème journées de Médecine Foetale, Mar 2017, Nice, France
Conference papers hal-02459664v1

EXPLORATION DES FONCTIONS IMMUNOSUPPRESSIVES DES ARN NON CODANTS CONTENUS DANS LES EXOSOMES DU MÉLANOME

Delphine Fradin
3ème journées RepiCGO, Dec 2016, Brest, France
Conference papers hal-02459657v1

Influence de l'hyperglycémie sur la méthylation de l'ADN

Delphine Fradin
Automnales du GRRC, Nov 2015, Pornichet, France
Conference papers hal-02459651v1

EVOLUTION DES MARQUES ÉPIGÉNÉTIQUES AU COURS DE LA VIE

Delphine Fradin
ADELF-EPITER, Sep 2014, Nice, France
Conference papers hal-02459594v1

GÉNÉTIQUE ET ÉPIGÉNÉTIQUE DU COMPORTEMENT SOCIAL

Delphine Fradin
Journées de l'Ecole Doctorale Pierre Louis de Santé Publique, Oct 2012, Saint Malo, France
Conference papers hal-02459610v1

EPIGÉNÉTIQUE ET HYPERGLYCÉMIE : RÔLE DE LA MÉTHYLATION DANS LA RÉTINOPATHIE DIABÉTIQUE

Delphine Fradin
4e congrès annuel du CORDDIM, Sep 2012, Paris, France
Conference papers hal-02459620v1

Aging and DNA methylation

Delphine Fradin
Seventh Annual Grantee Meeting of Centers of Excellence in Genomic Science, Oct 2009, Huntsville, United States
Conference papers hal-02459631v1

INFLUENCE OF CONTROL SELECTION IN GENOME-WIDE ASSOCIATION STUDY: THE EXAMPLE OF DIABETES IN THE FRAMIGHAM HEART STUDY.

Delphine Fradin
Genetic Analysis Workshop 16, Sep 2008, Saint Louis, United States
Conference papers hal-02459645v1