Edith Le Floch

Ingénieur-Chercheur CEA, responsable de l'équipe Mathématiques et Statistiques du CNRGH
30
Documents

Publications

Publications

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Characterization of challenging forensic DNA traces using advanced molecular technologies

Amel Larnane , Caroline Lefèvre-Horgues , Corinne Cruaud , Cédric Fund , Edith Le Floch et al.
International Journal of Legal Medicine, 2025, 139 (4), pp.1511-1527. ⟨10.1007/s00414-025-03448-8⟩
Article dans une revue hal-05159911 v1
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Human genetic structure in Northwest France provides new insights into West European historical demography

Isabel Alves , Joanna Giemza , Michael Blum , Carolina Bernhardsson , Stéphanie Chatel et al.
Nature Communications, 2024, 15 (1), pp.6710. ⟨10.1038/s41467-024-51087-1⟩
Article dans une revue hal-04683810 v2
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Comprehensive catalog of variants potentially associated with hidradenitis suppurativa, including newly identified variants from a cohort of 100 patients

Kévin Muret , Vincent Le Goff , Claire Dandine-Roulland , Claire Hotz , Francette Jean-Louis et al.
International Journal of Molecular Sciences, 2024, 25 (19), pp.10374. ⟨10.3390/ijms251910374⟩
Article dans une revue cea-04719777 v1
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Layer myocardial strain is the most heritable echocardiographic trait

Olivier Huttin , Constance Xhaard , Claire Dandine-Roulland , Edith Le Floch , Delphine Bacq-Daian et al.
European Heart Journal - Cardiovascular Imaging, 2023, 24 (10), pp.1394-1403. ⟨10.1093/ehjci/jead146⟩
Article dans une revue hal-04192912 v1
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Shared Heritability of Blood Pressure and Pulse Wave Velocity

Constance Xhaard , Pierre de Villemereuil , Athanase Benetos , Erwan Bozec , Claire Dandine-Roulland et al.
Hypertension, 2023, 80 (7), pp.1526-1533. ⟨10.1161/HYPERTENSIONAHA.122.20740⟩
Article dans une revue hal-04193168 v1
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Weak association between genetic markers of hyperuricemia and cardiorenal outcomes: insights from the STANISLAS study cohort with a 20‐year follow‐up

Mehmet Kanbay , Constance Xhaard , Edith Le Floch , Claire Dandine-Roulland , Nicolas Girerd et al.
Journal of the American Heart Association, 2022, 11, pp.e023301. ⟨10.1161/JAHA.121.023301⟩
Article dans une revue hal-03652891 v1
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Fatty acid desaturase genetic variations and dietary omega-3 fatty acid intake associate with arterial stiffness

Magnus Bäck , Constance Xhaard , Raphael Rouget , Quentin Thuillier , Oscar Plunde et al.
European Heart Journal Open, 2022, pp.oeac016. ⟨10.1093/ehjopen/oeac016⟩
Article dans une revue hal-03613927 v1
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Identification of risk loci for primary aldosteronism in genome-wide association studies

Edith Le Floch , Teresa Cosentino , Casper K Larsen , Felix Beuschlein , Martin Reincke et al.
Nature Communications, 2022, 13 (1), pp.5198. ⟨10.1038/s41467-022-32896-8⟩
Article dans une revue inserm-03845164 v1
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Genome-wide haplotype association study in imaging genetics using whole-brain sulcal openings of 16,304 UK Biobank subjects

Slim Karkar , Claire Dandine-Roulland , Jean-François Mangin , Yann Le Guen , Cathy Philippe et al.
European Journal of Human Genetics, 2021, 29 (9), pp.1424-1437. ⟨10.1038/s41431-021-00827-8⟩
Article dans une revue cea-04359983 v1
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Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort

Constance Xhaard , Raphaël Rouget , Nicolas Vodovar , Edith Le Floch , Claire Dandine‐roulland et al.
ESC Heart Failure, 2021, ⟨10.1002/ehf2.13674⟩
Article dans une revue hal-03414759 v1
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PIntMF: Penalized Integrative Matrix Factorization method for multi-omics data

Morgane Pierre-Jean , Florence Mauger , Jean-François Deleuze , Edith Le Floch
Bioinformatics, 2021, 38 (4), pp.900-907. ⟨10.1093/bioinformatics/btab786⟩
Article dans une revue hal-03154671 v1
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Region-specific expression of young small-scale duplications in the human central nervous system

Solène Brohard-Julien , Vincent Frouin , Vincent Meyer , Smahane Chalabi , Jean-François Deleuze et al.
BMC Ecology and Evolution, 2021, 21, pp.59. ⟨10.1186/s12862-021-01794-w⟩
Article dans une revue hal-03353892 v1
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Genetics of severe hypercholesterolemia in the general population

Constance Xhaard , João Pedro Ferreira , Edith Le Floch , Zohra Lamiral , Claire Dandine-Roulland et al.
Journal of Atherosclerosis Prevention and Treatment, 2021, 12 (3), pp.73-83. ⟨10.53590/japt.02.1026⟩
Article dans une revue hal-03579126 v1
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Circulating plasma proteins and new-onset diabetes in a population-based study: proteomic and genomic insights from the STANISLAS cohort

Joao Pedro Ferreira , Zohra Lamiral , Constance Xhaard , Kévin Duarte , Emmanuel Bresso et al.
European Journal of Endocrinology, 2020, 183 (3), pp.285-295. ⟨10.1530/EJE-20-0246⟩
Article dans une revue hal-02917113 v1
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Exploring the link between additive heritability and prediction accuracy from a ridge regression perspective

Arthur Frouin , Claire Dandine-Roulland , Morgane Pierre-Jean , Jean-François Deleuze , Christophe Ambroise et al.
Frontiers in Genetics, 2020, 11, pp.581594. ⟨10.3389/fgene.2020.581594⟩
Article dans une revue cea-04419427 v1

Where are the missing gene defects in inherited retinal disorders? Intronic and synonymous variants contribute at least to 4% of CACNA1F-mediated inherited retinal disorders

Christina Zeitz , Christelle Michiels , Marion Neuillé , Christoph Friedburg , Christel Condroyer et al.
Human Mutation, 2019, 40 (6), pp.765-787. ⟨10.1002/humu.23735⟩
Article dans une revue hal-02616948 v1
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Clustering and variable selection evaluation of 13 unsupervised methods for multi-omics data integration

Morgane Pierre-Jean , Jean-François Deleuze , Edith Le Floch , Florence Mauger
Briefings in Bioinformatics, 2019, ⟨10.1093/bib/bbz138⟩
Article dans une revue cea-02393847 v1
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Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene–environment interaction study

José Oliveira , Rémi Kazma , Edith Le Floch , Meriem Bennabi , Nora Hamdani et al.
International Journal of Bipolar Disorders, 2016, 4 (1), pp.11. ⟨10.1186/s40345-016-0052-6⟩
Article dans une revue cea-04557509 v1

Voxelwise multivariate statistics and brain-wide machine learning using the full diffusion tensor.

Anne-Laure Fouque , Pierre Fillard , Anne Bargiacchi , Arnaud Cachia , Monica Zilbovicius et al.
Med Image Comput Comput Assist Interv, 2011, 14 (Pt 2), pp.9-16
Article dans une revue hal-00700801 v1
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PIntMF : Une méthode de factorisation matricielle pénalisée pour l'intégration de données multi-omiques

Morgane Pierre-Jean , Florence Mauger , Jean-François Deleuze , Edith Le Floch
JDS 21 - 52èmes Journées de Statistique de la Société Française de Statistique (SFdS) (reportées en 2021), Jun 2021, Nice, France
Communication dans un congrès hal-02945894 v1
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Multivariate haplotype analysis of 96 sulci opening for 15,612 UK-Biobank subjects

S. Karkar , A. Gloaguen , Y. Le Guen , Morgane Pierre-Jean , Claire Dandine-Roulland et al.
ISBI 2019 - Proceedings of the IEEE International Symposium on Biomedical Imaging, Apr 2019, Venice, Italy. ⟨10.1109/isbi.2019.8759497⟩
Communication dans un congrès cea-02016827 v1

Dimension reduction and regularisation combined with Partial Least Squares in high dimensional imaging-genetics studies

Edith Le Floch , Laura Trinchera , Arthur Tenenhaus , Jean-Baptiste Poline , Vincent Frouin
PLS'12, May 2012, Houston, United States. CD-ROM Proceedings (8 p.)
Communication dans un congrès hal-00752233 v1

A Variable Selection via Correlated Component PLS-type Regression

Laura Trinchera , Edith Le Floch , Arthur Tenenhaus
8th Scientific Meeting of the CLAssification and Data Analysis Group of the Italian Statistical Society (GLADAG'11), Sep 2011, Pavia, Italy. 4 p
Communication dans un congrès hal-00656584 v1
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Variable Selection in Partial Least Squares Methods: overview and recent developments

Laura Trinchera , Edith Le Floch , Arthur Tenenhaus
International Symposium on Business and Industrial Statistics (ISBI'10), Jul 2010, Portoroz, Slovenia. pp.102
Communication dans un congrès hal-00529791 v1

Dimension Reduction and Regularization Combined with Partial Least Squares in High Dimensional Imaging Genetics Studies

Edith Le Floch , Laura Trinchera , Vincent Guillemot , Arthur Tenenhaus , Jean-Baptiste Poline et al.
New Perspectives in Partial Least Squares and Related Methods, Springer, pp.147-158, 2013, Springer Proceedings in Mathematics & Statistics, ⟨10.1007/978-1-4614-8283-3_9⟩
Chapitre d'ouvrage istex hal-01068983 v1