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Emilie Layre

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Publications

Image document

A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection

Sergio Fabián Mosquera-Restrepo , Sophie Zuberogoïtia , Lucie Gouxette , Emilie Layre , Martine Gilleron et al.
Nature Communications, 2022, 13 (1), pp.7751. ⟨10.1038/s41467-022-35453-5⟩
Article dans une revue hal-04260471 v1

Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles

José Luis Marín Franco , Melanie Genoula , Dan Corral , Gabriel Duette , Malena Ferreyra et al.
Journal of Extracellular Vesicles, 2021, 10 (3), pp.108547. ⟨10.1002/jev2.12046⟩
Article dans une revue hal-03367142 v1
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Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients

Marthe Jøntvedt Jørgensen , Kristin Nore , Hans Christian D. Aass , Emilie Layre , Jérôme Nigou et al.
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.669623. ⟨10.3389/fcimb.2021.669623⟩
Article dans une revue hal-03445397 v1
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Host-Derived Lipids from Tuberculous Pleurisy Impair Macrophage Microbicidal-Associated Metabolic Activity

José Luis Marín Franco , Melanie Genoula , Dan Corral , Gabriel Duette , Malena Ferreyra et al.
Cell Reports, 2020, 33 (13), pp.108547. ⟨10.1016/j.celrep.2020.108547⟩
Article dans une revue hal-03450535 v2
Image document

Trafficking of Mycobacterium tuberculosis Envelope Components and Release Within Extracellular Vesicles: Host-Pathogen Interactions Beyond the Wall

Emilie Layre
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01230⟩
Article dans une revue hal-03096291 v1
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Mycobacterium tuberculosis releases an antacid that remodels phagosomes

Jeffrey Buter , Tan-Yun Cheng , Marwan Ghanem , Anita E Grootemaat , Sahadevan Raman et al.
Nature Chemical Biology, 2019, 15 (9), pp.889-899. ⟨10.1038/s41589-019-0336-0⟩
Article dans une revue hal-02407888 v1
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Metabolic anticipation in Mycobacterium tuberculosis

Hyungjin Eoh , Zhe Wang , Emilie Layre , Poonam Rath , Roxanne Morris et al.
Nature Microbiology, 2017, 2 (8), ⟨10.1038/nmicrobiol.2017.84⟩
Article dans une revue hal-02407897 v1

Protective efficacy of a lipid antigen vaccine in a guinea pig model of tuberculosis

Gerald Larrouy-Maumus , Emilie Layre , Simon Clark , Jacques Prandi , Emma Rayner et al.
Vaccine, 2017, 35 (10), pp.1395-1402. ⟨10.1016/j.vaccine.2017.01.079⟩
Article dans une revue hal-02407908 v1

Rifampin Resistance Mutations Are Associated with Broad Chemical Remodeling of Mycobacterium tuberculosis

Nivedita Lahiri , Rupal Shah , Emilie Layre , David Young , Chris Ford et al.
Journal of Biological Chemistry, 2016, 291 (27), pp.14248-14256. ⟨10.1074/jbc.m116.716704⟩
Article dans une revue hal-02407926 v1

Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens

Martine Gilleron , Marco Lepore , Emilie Layre , Diane Cala-De paepe , Naila Mebarek et al.
Cell Chemical Biology, 2016, 23 (9), pp.1147-1156. ⟨10.1016/j.chembiol.2016.07.021⟩
Article dans une revue hal-03096294 v1

Bee venom processes human skin lipids for presentation by CD1a

Elvire Bourgeois , Sumithra Subramaniam , Tan-Yun Cheng , Annemieke de Jong , Emilie Layre et al.
Journal of Experimental Medicine, 2015, 212 (2), pp.149-163. ⟨10.1084/jem.20141505⟩
Article dans une revue hal-03096324 v1

Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules

Shih-Jung Pan , Asa Tapley , John Adamson , Tessa Little , Michael Urbanowski et al.
Journal of Infectious Diseases, 2015, 212 (11), pp.1827-1834. ⟨10.1093/infdis/jiv312⟩
Article dans une revue hal-03096320 v1

In Vivo Biosynthesis of Terpene Nucleosides Provides Unique Chemical Markers of Mycobacterium tuberculosis Infection

David c. Young , Emilie Layre , Shih-Jung Pan , Asa Tapley , John Adamson et al.
Chemistry & biology, 2015, 22 (4), pp.516-526. ⟨10.1016/j.chembiol.2015.03.015⟩
Article dans une revue hal-03096321 v1

Human T cells use CD1 and MR1 to recognize lipids and small molecules

Emilie Layre , Annemieke de Jong , David Branch Moody
Current Opinion in Chemical Biology, 2014, 23, pp.31-38. ⟨10.1016/j.cbpa.2014.09.007⟩
Article dans une revue hal-03096325 v1

Mycobacterial Lipidomics

Emilie Layre , Reem Al-Mubarak , J.T. Belisle , D. Branch Moody
Microbiology Spectrum, 2014, ⟨10.1128/microbiolspec⟩
Article dans une revue hal-03096315 v1

Lipidomic profiling of model organisms and the world's major pathogens

Emilie Layre , D. Branch Moody
Biochimie, 2013, 95 (1), pp.109-115. ⟨10.1016/j.biochi.2012.08.012⟩
Article dans une revue hal-03096331 v1
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Deciphering the Role of CD1e Protein in Mycobacterial Phosphatidyl- myo -inositol Mannosides (PIM) Processing for Presentation by CD1b to T Lymphocytes

Diane Cala-de Paepe , Emilie Layre , Gaëlle Giacometti , Luis Garcia-Alles , Lucia Mori et al.
Journal of Biological Chemistry, 2012, 287 (37), pp.31494-31502. ⟨10.1074/jbc.M112.386300⟩
Article dans une revue hal-03096337 v1
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Deciphering sulfoglycolipids of Mycobacterium tuberculosis

Emilie Layre , Diane Cala-de Paepe , Gerald Larrouy-Maumus , Julien Vaubourgeix , Sathish Mundayoor et al.
Journal of Lipid Research, 2011, 52 (6), pp.1098-1110. ⟨10.1194/jlr.M013482⟩
Article dans une revue hal-03096390 v1

A Comparative Lipidomics Platform for Chemotaxonomic Analysis of Mycobacterium tuberculosis

Emilie Layre , Lindsay Sweet , Sunhee Hong , Cressida a. Madigan , Danielle Desjardins et al.
Chemistry & biology, 2011, 18 (12), pp.1537-1549. ⟨10.1016/j.chembiol.2011.10.013⟩
Article dans une revue hal-03096389 v1

Mycolic Acids Constitute a Scaffold for Mycobacterial Lipid Antigens Stimulating CD1-Restricted T Cells

Emilie Layre , Anthony Collmann , Max Bastian , Sabrina Mariotti , Jerzy Czaplicki et al.
Chemistry & biology, 2009, 16 (1), pp.82-92. ⟨10.1016/j.chembiol.2008.11.008⟩
Article dans une revue hal-03177940 v1
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The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments

Blandine Maître , Catherine Angénieux , Virginie Wurtz , Emilie Layre , Martine Gilleron et al.
Biochemical Journal, 2009, 419 (3), pp.661-668. ⟨10.1042/BJ20082204⟩
Article dans une revue hal-00479127 v1

Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation.

Sylvie Tourne , Blandine Maitre , Anthony Collmann , Emilie Layre , Sabrina Mariotti et al.
Journal of Immunology, 2008, 180 (6), pp.3642-6
Article dans une revue inserm-00351035 v1

Does Mycobacterium tuberculosis produce even more immunomodulatory lipids? Contribution of an unbiased lipidomic approach (EMBO)

Tamara Mickova , Jérôme Nigou , Martine Gilleron , Emilie Layre
EMBO Workshop Pathogen immunity and signaling, Apr 2024, San Servolo Venice, Italy
Poster de conférence hal-05024266 v1

Extracellular vesicles released during Mycobacterium tuberculosis infection: content in immunomodulatory lipids and interactions with macrophages (EMBO)

Pierre Boyer , Hanamée Faugeras , Isabelle Vergne , Tamara Mickova , Alain Vercellone et al.
EMBO Workshop Pathogen immunity and signaling, Apr 2024, San Servolo Venice, Italy
Poster de conférence hal-05024264 v1

Processing of microbial glycolipids in lysosome expands the repertoire of TLR2 agonists

Christophe Carrat , Sonia Belkai , Emilie Layre , Diane Cala - de Paepe , Landry Blanc et al.
18th GERLI Lipidomics meeting entitled "Lipids, from molecular aspects to human diseases", Oct 2023, Paris, France
Poster de conférence hal-05023349 v1

A Mycobacterium tuberculosis lipid fingerprint in human breath allows tuberculosis detection

Sergio Fabián Mosquera-Restrepo , Sophie Zuberogoïtia , Lucie Gouxette , Emilie Layre , Martine Gilleron et al.
GERLI 18th International lipidomics meeting “Tailored lipids: from molecular asopects to human diseases”, Oct 2023, Paris, France
Poster de conférence hal-05024147 v1

Extracellular vesicles released during Mycobacterium tuberculosis infection: bacterial lipid content and roles in host-pathogen interactions (GF TB Vaccines)

Emilie Layre
6th Global Forum on TB Vaccines, Feb 2022, Toulouse, France
Poster de conférence hal-05052718 v1

Vesicles released during Mycobacterium tuberculosis infection: immunomodulatory (glyco)lipids and role in host-pathogen interactions (ISEV)

Emilie Layre , Pierre Boyer , Jérôme Nigou
Annual Meeting of the International Society of Extracellular Vesicles, Jul 2020, Online (covid), France
Poster de conférence hal-05024246 v1

Bacterial lipid content of extracellular vesicles released by macrophages infected by Mycobacterium tuberculosis (ISEV 2020)

Pierre Boyer , Jérôme Nigou , Emilie Layre
Annual Meeting of the International Society of Extracellular Vesicles, Jul 2020, Online (covid), France
Poster de conférence hal-05024260 v1
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Targeted Lipidomics of Mycobacterial Lipids and Glycolipids

Emilie Layre
Mycobacteria Protocols, 2314, Springer US, pp.549-577, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1460-0_24⟩
Chapitre d'ouvrage hal-03445430 v1