Emilie Roger

66
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Publications

Publications

Specific quantification of intact lipid nanocapsules in rats using FRET: biodistribution and PBPK model development

Rana Elfatairi , Jessica Ou , Vincent Lebreton , Mariam Mahdjoub , Norraseth Kaeokhamloed et al.

Nanomedicine, 2025, 20 (10), pp.1101-1112. ⟨10.1080/17435889.2025.2492537⟩

Article dans une revue hal-05242719v1
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Thymoquinone loaded lipid nanocapsule dispersion: two methods of preparation, characterization and in vitro evaluations for oral administration

Mouna Selmi , Amine Trabelsi , Nolwenn Lautram , David Dallerac , Guillaume Lefebvre et al.

Pharmaceutical Development and Technology, In press, ⟨10.1080/10837450.2024.2448616⟩

Article dans une revue hal-04875865v1

Nano-Ayurvedic Medicine Approaches Using Ginkgo biloba-Phytochemicals Functionalized Gold Nanoparticles Against Breast Cancer

Velaphi Thipe , Nya Hall , Amoolya Pandurangi , Samuel Ajayi , Prosper Emeh et al.

Nanotechnology, Science and Applications, 2024, Volume 17, pp.189-210. ⟨10.2147/NSA.S478533⟩

Article dans une revue hal-05173395v1
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Internalization and mechanisms of toxicity of lipid nanocapsules in HepG2 and HepaRG hepatoma cells upon acute and chronic exposures

Flavien Delaporte , Emilie Roger , Jérome Bejaud , Pascal Loyer , Frédéric Lagarce et al.

International Journal of Pharmaceutics, 2024, 667, pp.124815. ⟨10.1016/j.ijpharm.2024.124815⟩

Article dans une revue hal-04751862v1
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Thymoquinone-loaded lipid nanocapsules with promising anticancer activity for colorectal cancer

Mouna Selmi , Abir Salek , Mahassen Barboura , Leila Njim , Amine Trabelsi et al.

Nanoscale Advances, 2023, ⟨10.1039/d3na00445g⟩

Article dans une revue hal-04210022v1
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Evidence of residual micellar structures in a lipid nanocapsule dispersion. A multi-technique approach

Emilie Roger , Florence Franconi , Tran Anh Thu Do , Carl Simonsson , Benjamin Siegler et al.

Journal of Controlled Release, 2023, 364, pp.700-717. ⟨10.1016/j.jconrel.2023.10.054⟩

Article dans une revue hal-04295223v1
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Drug Delivery Systems for the Oral Administration of Antimicrobial Peptides: Promising Tools to Treat Infectious Diseases

Caroline Deshayes , Md Arafath , Véronique Apaire-Marchais , Emilie Roger

Frontiers in Medical Technology, 2022, 3, ⟨10.3389/fmedt.2021.778645⟩

Article dans une revue hal-03615302v1
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Green nanotechnology—An innovative pathway towards biocompatible and medically relevant gold nanoparticles

Velaphi Thipe , Alice Karikachery , Pinar Çakilkaya , Umer Farooq , Hussein Genedy et al.

Journal of Drug Delivery Science and Technology, 2022, 70, ⟨10.1016/j.jddst.2022.103256⟩

Article dans une revue hal-03615301v1

Pharmacokinetics of intact lipid nanocapsules using new quantitative FRET technique

Vincent Lebreton , Norraseth Kaeokhamloed , Anastasiia Vasylaki , Gregory Hilairet , Adélie Mellinger et al.

Journal of Controlled Release, 2022, 351, pp.681-691. ⟨10.1016/j.jconrel.2017.03.005⟩

Article dans une revue hal-02341627v1
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FRET as the tool for in vivo nanomedicine tracking

Norraseth Kaeokhamloed , Samuel Legeay , Emilie Roger

Journal of Controlled Release, 2022, 349, pp.156-173. ⟨10.1016/j.jconrel.2022.06.048⟩

Article dans une revue hal-03720790v1
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A new method to prepare microparticles based on an Aqueous Two-Phase system (ATPS), without organic solvents

Florence Dumas , Jean-Pierre Benoit , Patrick Saulnier , Emilie Roger

Journal of Colloid and Interface Science, 2021, 599, pp.642-649. ⟨10.1016/j.jcis.2021.03.141⟩

Article dans une revue hal-03388118v1
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Organic nanoparticle tracking during pharmacokinetic studies

Samuel Bonnet , Rana Elfatairi , Florence Franconi , Emilie Roger , Samuel Legeay

Nanomedicine, 2021, ⟨10.2217/nnm-2021-0155⟩

Article dans une revue hal-03446719v1
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Aqueous Two-Phase Systems: simple one-step process formulation and phase diagram for characterisation

Florence Dumas , Emilie Roger , Johanna Rodriguez , Lazhar Benyahia , Jean-Pierre Benoit

Colloid and Polymer Science, 2020, ⟨10.1007/s00396-020-04748-8⟩

Article dans une revue hal-02973278v1
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Nanocarriers and nonviral methods for delivering antiangiogenic factors for glioblastoma therapy: the story so far

Anne Clavreul , Milad Pourbaghi-Masouleh , Emilie Roger , Philippe Menei

International Journal of Nanomedicine, 2019, 14, pp.2497-2513. ⟨10.2147/IJN.S194858⟩

Article dans une revue hal-02616075v1
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Advances in treatment formulations for acute myeloid leukemia

Thomas Briot , Emilie Roger , Sylvain Thépot , Frédéric Lagarce

Drug Discovery Today Biosilico, 2018, Epub ahead of print. ⟨10.1016/j.drudis.2018.05.040⟩

Article dans une revue inserm-01809889v1
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Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma

Anne Clavreul , Emilie Roger , Milad Pourbaghi-Masouleh , Laurent Lemaire , Clément Tétaud et al.

Drug Delivery, 2018, 25 (1), pp.1756 - 1765. ⟨10.1080/10717544.2018.1507061⟩

Article dans une revue inserm-01908758v1
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Development and in vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemia

Thomas Briot , Emilie Roger , Nolwenn Lautram , Alexis Verger , Anne Clavreul et al.

International Journal of Nanomedicine, 2017, Volume 12, pp.8427 - 8442. ⟨10.2147/IJN.S147659⟩

Article dans une revue inserm-01668530v1
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Human mesenchymal stromal cells as cellular drug-delivery vectors for glioblastoma therapy: a good deal?

Anne Clavreul , Milad Pourbaghi-Masouleh , Emilie Roger , Nolwenn Lautram , Claudia Montero-Menei et al.

Journal of Experimental and Clinical Cancer Research, 2017, 36 (1), pp.135. ⟨10.1186/s13046-017-0605-2⟩

Article dans une revue inserm-01631360v1
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Models for drug absorption from the small intestine: where are we and where are we going?

Pierre-André Billat , Emilie Roger , Sébastien Faure , Frédéric Lagarce

Drug Discovery Today, 2017, 22 (5), pp.761-775. ⟨10.1016/j.drudis.2017.01.007⟩

Article dans une revue hal-02615955v1

Spontaneous nano-emulsification: Process optimization and modeling for the prediction of the nanoemulsion’s size and polydispersity

Guillaume Lefebvre , Jérémie Riou , Guillaume Bastiat , Emilie Roger , Kristen Frombach et al.

International Journal of Pharmaceutics, 2017, 534 (1-2), pp.220-228. ⟨10.1016/j.ijpharm.2017.10.017⟩

Article dans une revue hal-02341597v1
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Lipid nanocapsules maintain full integrity after crossing a human intestinal epithelium model

Emilie Roger , Jean Christophe Gimel , Conor Bensley , Andrey S Klymchenko , Jean Pierre Benoit

Journal of Controlled Release, 2017, 253, pp.11-18. ⟨10.1016/j.jconrel.2017.03.005⟩

Article dans une revue hal-03805634v1
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Alginate/Chitosan Compact Polyelectrolyte Complexes: A Cell and Bacterial Repellent Material

Thida Phoeung , Maria Vittoria Spanedda , Emilie Roger , Béatrice Heurtault , Sylvie Fournel et al.

Chemistry of Materials, 2017, 29 (24), pp.10418-10425. ⟨10.1021/acs.chemmater.7b03863⟩

Article dans une revue hal-02142349v1

How to design the surface of peptide-loaded nanoparticles for efficient oral bioavailability?

Hélène Malhaire , Jean-Christophe Gimel , Emilie Roger , Jean-Pierre Benoît , Frédéric Lagarce

Advanced Drug Delivery Reviews, 2016, pp.1-17. ⟨10.1016/j.addr.2016.03.011⟩

Article dans une revue hal-01392464v1

On the Benefits of Rubbing Salt in the Cut: Self-Healing of Saloplastic PAA/PAH Compact Polyelectrolyte Complexes

Andreas Reisch , Emilie Roger , Thida Phoeung , Cyril Antheaume , Camille Orthlieb et al.

Advanced Materials, 2014, 26 (16), pp.2547-2551. ⟨10.1002/adma.201304991⟩

Article dans une revue istex hal-01389168v1

Compact saloplastic poly(acrylic acid)/poly(allylamine) complexes: kinetic control over composition, microstructure, and mechanical properties

Andreas Reisch , Patricia Tirado , Emilie Roger , Fouzia Boulmedais , Dominique Collin et al.

Advanced Functional Materials, 2013, 23, pp.673-682

Article dans une revue hal-00966799v1

Catalytic Saloplastics: Alkaline Phosphatase Immobilized and Stabilized in Compacted Polyelectrolyte Complexes

Patricia Tirado , Andreas Reisch , Emilie Roger , Fouzia Boulmedais , Loïc Jierry et al.

Advanced Functional Materials, 2013, pp.4785-4792. ⟨10.1002/adfm.201300117⟩

Article dans une revue istex hal-01389162v1

Highly lipophilic fluorescent dyes in nano-emulsions: towards bright non-leaking nano-droplets.

Andrey S Klymchenko , Emilie Roger , Nicolas Anton , Halina Anton , Ievgen Shulov et al.

RSC Advances, 2012, 2 (31), pp.11876-11886. ⟨10.1039/c2ra21544f⟩

Article dans une revue hal-00783454v1

Development and characterization of a novel lipid nanocapsule formulation of Sn38 for oral administration

Emilie Roger , Frédéric Lagarce , Jean-Pierre Benoît

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, 2011, 79 (1), pp.181-8. ⟨10.1016/j.ejpb.2011.01.021⟩

Article dans une revue istex hal-03165447v1

Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells.

Emilie Roger , Frédéric Lagarce , Emmanuel Garcion , Jean-Pierre Benoît

European Journal of Pharmaceutical Sciences, 2010, 40 (5), pp.422-9

Article dans une revue hal-03171843v1
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The rise and rise of stealth nanocarriers for cancer therapy: passive versus active targeting

Ngoc Trinh Huynh , Emilie Roger , Nolwenn Lautram , Jean-Pierre Benoît , Catherine Passirani-Malleret

Nanomedicine, 2010, 5 (9), pp.1415-33. ⟨10.2217/nnm.10.113⟩

Article dans une revue hal-03171842v1

Biopharmaceutical parameters to concider in order to alter the fate of nanocarriers after oral delivery.

Emilie Roger , Frédéric Lagarce , Emmanuel Garcion , Jean-Pierre Benoît

Nanomedicine, 2010, 5 (2), pp.287-306

Article dans une revue hal-03171857v1

Lipid nanocapsules: Ready-to-use nanovectors for the aerosol delivery of paclitaxel

José Hureaux , Frédéric Lagarce , Frédéric Gagnadoux , Laurent Vecellio , Anne Clavreul et al.

European Journal of Pharmaceutics and Biopharmaceutics, 2009, 73 (2), pp.239 - 246. ⟨10.1016/j.ejpb.2009.06.013⟩

Article dans une revue istex hal-03165461v1

Lipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosis

Emilie Roger , Frédéric Lagarce , Emmanuel Garcion , Jean-Pierre Benoît

Journal of controlled release : official journal of the Controlled Release Society, 2009, 140 (2), pp.174-81

Article dans une revue hal-03171849v1

The gastrointestinal stability of lipid nanocapsules

Emilie Roger , Frédéric Lagarce , Jean-Pierre Benoît

International Journal of Pharmaceutics, 2009, 379 (2), pp.260-5

Article dans une revue hal-03171870v1

Intranasal route for glioblastoma stem cells treatment using synergistic inhibitors

Cécile Doualle , Emilie Roger , Sifon Edem , Jérôme Bejaud , Patrick Saulnier et al.

SFNano 2024, Dec 2024, Toulouse, France

Poster de conférence hal-04849947v1

Development of lipid nanocapsule for oral treatment of liver cancer.

Sihem Khelil , Nolwenn Lautram , David Dallerac , Marie-Claire Venier-Julienne , Camille Savary et al.

Journée de la SFR ICAT 2022, Jun 2022, Angers, France

Poster de conférence hal-04105639v1

Experimental evidence of residual micellar structures in lipid nanocapsules suspensions

Tran Anh Thu Do , Emilie Roger , Florence Franconi , Benjamin Siegler , Rodolphe Perrot et al.

SFnano, Dec 2022, Strasbourg, France.

Poster de conférence hal-03890468v1
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In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules: what formulation for a better biocompatibility?

Flavien Delaporte , Emilie Roger , Frédéric Lagarce , Camille Savary

SFNano, Dec 2021, Angers, France

Poster de conférence hal-03695357v1

Pharmacokinetics and oral absorption of different lipid nanocapsules: new quantitative FRET technique revealing PEGylation increasing the particle’s clearance

Norraseth Kaeokhamloed , Vincent Lebreton , Jérôme Béjaud , Florence Gattacceca , Emilie Roger et al.

GMP 2021 Symposium, Oct 2021, Paris, France

Poster de conférence hal-03528600v1

Population pharmacokinetic modelling of intravenous LNCs FRET in rat

Vincent Lebreton , Norraseth Kaeokhamloed , Florence Gattacceca , Jérôme Béjaud , Patrick Saulnier et al.

GMP 2021 Symposium, Oct 2021, Paris, France

Poster de conférence hal-03528608v1

Aqueous Two Phase Systems: Physico-chemical Characterization By Phase Diagram Design

Florence Dumas , Emilie Roger , Lazhar Benyahia , Jean-Pierre Benoit

Controlled Release Society Annual Meeting & Exposition, Jul 2019, Valencia, Spain

Poster de conférence hal-02613941v1

Design of phase diagrams for characterization of aqueous two-phase systems

Florence Dumas , Johanna Rodriguez , Emilie Roger , Lazhar Benyahia , Jean-Pierre Benoit

Journée scientifique de la SFR ICAT4208, 2018, Angers, France. , 2018

Poster de conférence hal-02616042v1

In vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemia

Thomas Briot , Emilie Roger , Nolwenn Lautram , Alexis Verger , Anne Clavreul et al.

4th annual meeting on Nanomedicine, 2017, Bordeaux, France. , 2017

Poster de conférence hal-02616000v1

Formulation of curcumin lipid nanocapsule-loaded gels for inflammatory bowel disease application

Chithdavone Her , Marie-Claire Venier-Julienne , Emilie Roger

La journée scientifique de la SFR ICAT, 2017, Angers, France. 2017

Poster de conférence hal-02615983v1

Formulation and characterization of "water-in-water" emulsion systems

Florence Dumas , Emilie Roger , Lazhar Benyahia , Jean-Pierre Benoit

SF Nano 2017, 2017, Bordeaux, France. , 2017

Poster de conférence hal-02616016v1

Formulation et caractérisation des systèmes d’émulsions dits « eau dans eau »

Florence Dumas , Emilie Roger , Jean-Pierre Benoit

Journée Scientifique de la SFR ICAT4208, 2017, Angers, France. , 2017

Poster de conférence hal-02616017v1

Development of decitabine nano objects for oral administration

Thomas Briot , Emilie Roger , Frédéric Lagarce

4th Congress on Innovation in Drug Delivery, 2016, Antibes, France. 2016

Poster de conférence hal-02615971v1

New lipid nanocapsules for decitabine encapsulation

Thomas Briot , Emilie Roger , Nolwenn Lautram , Frédéric Lagarce

Journées annuelles SFNano, 2016, Paris, France. 2016

Poster de conférence hal-02615972v1

In vivo evaluation of novel lipid nanocapsule formulation of SN38

Emilie Roger , Frédéric Lagarce , Jean-Pierre Benoît

25 eme réunion annuelle du Groupe Thématique de Recherche sur les Vecteurs, 2010, Toulouse, France. 2010

Poster de conférence hal-03180842v1
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BEHAVIOR OF LIPID NANOCAPSULES AFTER ORAL ADMINISTRATION

Emilie Roger

Summer School « Innovations in Delivery and Targeting », Université de Strasbourg, Jun 2023, Strasbourg, France

Communication dans un congrès hal-04268183v1
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In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules

Flavien Delaporte , Emilie Roger , Frédéric Lagarce , Camille Savary

Journée de la Société Française de Recherche ICAT, Jun 2022, Angers, France

Communication dans un congrès hal-03695378v1

Oral application of lipid nanocapsules: behavior of nanoparticles?

Emilie Roger

NANOMED EMJMD Workshop 2022, Jul 2022, Pavia, Italy

Communication dans un congrès hal-03738515v1
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In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules: what formulation for a better biocompatibility?

Flavien Delaporte , Emilie Roger , Frédéric Lagarce , Camille Savary

Société de Toxicologie Cellulaire et Moléculaire : Les Jeunes Toxicologues, Mar 2022, Online, France

Communication dans un congrès hal-03695367v1

ORAL APPLICATION OF LIPID NANOCAPSULES: BEHAVIOR OF NANOPARTICLES?

Emilie Roger

5th NANOMED Workshop "From biotechnology to nanobiotechnology and vaccines", University of Pavia, Jul 2022, Pavia, Italy

Communication dans un congrès hal-04268193v1
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Nanocapsules lipidiques : quelle taille pour une meilleure biocompatibilité hépatique ?

Flavien Delaporte , Emilie Roger , Frédéric Lagarce , Camille Savary

Journée de la Société Française de Recherche ICAT, Jun 2021, Angers, France

Communication dans un congrès hal-03695306v1
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In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules

Flavien Delaporte , Emilie Roger , Catherine Passirani , Camille Savary

Stratagem Cost, Sep 2021, Prague, Czech Republic

Communication dans un congrès hal-03695352v1

Decitabine encapsulation in nanovector to improve acute myeloid leukemia treatment

Jérôme Bejaud , Sylvain Thepot , Frédéric Lagarce , Thomas Briot , Emilie Roger et al.

Journée scientifique de la SFR ICAT 4208, 2018, Angers, France

Communication dans un congrès hal-02616020v1

Lipid nanocapsules: a new platform for oral drug delivery system ?

Emilie Roger

11th World Drug Delivery Summit, 2017, Baltimore, United States

Communication dans un congrès hal-02615984v1

Combined strategy based on pre-activated analogs of oxazaphosphorines for increased therapeutic index and immune modulation

Julia Delahousse , Charles Skarbek , Valentine Gauthier , Mélanie Desbois , Emilie Roger et al.

AACR Annual Meeting 2017, 2017, Washington, United States. ⟨10.1158/1538-7445.AM2017-2195⟩

Communication dans un congrès hal-02615988v1

Formulation and evaluation of new oxazaphosphorine prodrugs-loaded lipid nanocapsules for cancer treatment

Henri Gonde , Emilie Roger , Charles Skarbek , Nolwenn Lautram , Angelo Paci et al.

4th Congress on Innovation in Drug Delivery (APGI/ADRITELF), 2016, Juan les Pins, France

Communication dans un congrès hal-02615967v1

New oxazaphosphorine prodrug’s for immunotherapy and n anomedicine against cancer

Charles Skarbek , Henri Gonde , Mélanie Desbois , Julia Delahousse , Nathalie Chapus-Gras et al.

107th AACR Annual Meeting, 2016, New Orleans, United States

Communication dans un congrès hal-02615962v1

Assessment of the diffusion coefficient of nanocarriers with the fluorescence recovery technique in gastrointestinal mucus

Alison Dénarnaud , Jérémie Riou , Rodolphe Perrot , Emilie Roger , Frédéric Lagarce et al.

Crossing Biological Barriers - Advances in Nanocarriers Design for Targeted Drug Delivery, 2015, Dresde, Germany

Communication dans un congrès hal-02615956v1

Transport of therapeutics across intestinal epithelium

Frédéric Lagarce , Emilie Roger , Sylvia Muro

Drug delivery across physiological barriers, CRC Press, pp.181-208, 2016, 978-981-4669-41-2. ⟨10.1201/b19907-10⟩

Chapitre d'ouvrage hal-01393795v1