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Eyad ALMOUAZEN

20
Documents

Présentation

**Sep 2014 – Present Associated Professor** University Lyon 1 Teaching at **Faculty of Pharmacy ISPB**, Pharmaceutical and Cosmetic Technology Department Research at **LAGEP‐** **UMR CNRS 5007 – Pharmaceutical Engineering Team** Design and development of innovative dosage forms for therapeutic applications: working on the elaboration of pharmaceutical formulations, the development of required analytical methods and the needed biological evaluations. Main projects: - Development of antigen nanoparticles as a vaccine for veterinary applications. - Investigation of the therapeutic effects of nanoencapsulated vitamin D3. - Development of the polymeric nanoparticles for targeting immunity - Use of nano-encapsulated haptens to improve the performance of skin sensitization non-animal Innovative Drug Delivery Strategies **2012 – 2014 Temporary Assistant Professor** Faculty of Pharmacy ISPB, University Lyon 1, France Research: oral vaccine development for veterinary application **2009 – 2013 PhD student in Pharmaceutical Technology** LAGEP UMR CNRS 5007 and INSERM U1028, University Lyon1, France Thesis title: Development of polymeric nanoparticles for targeting and modulating macrophage functions. -Retinoic acid and vitamin D3 encapsulation by nanoprecipitation -Evaluation of nanoparticle uptake by macrophages in vitro and in vivo -Assessment of therapeutical potential of developed nanoparticles **Feb – July 2009 MSc Research internship** LAGEP UMR CNRS 5007 and INSERM U851, University Lyon1, France Project title: Use of nano-encapsulated haptens to improve the performance of skin sensitization non-animal test. -Elaboration of hapten loaded polymeric nanoparticle. -Test of nanoparticles on dendritic cells – T-cells co-culture. **Mar – Sep 2008 Formulation Engineer** Laboratory of skin care development, L’Oreal-Paris, Chevilly-Larue, France Project title: New formulation development for cleansing application. -Formulation and stability study of low viscosity emulsions. **Jan – Juin 2007 R&D Engineer** Expanscience Laboratories, Damascus, Syria -Performed new control methods -Validation of quality control protocols.

Publications

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Development of an oral nanovaccine for dogs against Echinococcus granulosus

Marine Leroux , Uruguaysito Benavides , Imène Hellel-Bourtal , Cecilia Silvarrey , Nadège Milhau
European Journal of Pharmaceutics and Biopharmaceutics, 2023, 192, pp.185-195. ⟨10.1016/j.ejpb.2023.09.012⟩
Article dans une revue hal-04504162v1

Supersaturable self-microemulsifying delivery systems: an approach to enhance oral bioavailability of benzimidazole anticancer drugs

Annalisa Rosso , Eyad Almouazen , Jorge Pontes , Valentina Andretto , Marine Leroux
Drug Delivery and Translational Research, 2021, 11, pp.675-691. ⟨10.1007/S13346-021-00904-X⟩
Article dans une revue hal-03175653v1
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Iodinated polymer nanoparticles as contrast agent for spectral photon counting computed tomography

Joëlle Balegamire , Marc Vandamme , Emmanuel Chereul , Salim Si-Mohamed , Samira Azzouz Maache
Biomaterials Science, 2020, 8 (20), pp.5715-5728. ⟨10.1039/D0BM01046D⟩
Article dans une revue hal-02946431v1
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Comparison of Three Processes for Parenteral Nanoemulsion Production: Ultrasounds, Microfluidizer, and Premix Membrane Emulsification

Océane Alliod , Eyad Almouazen , Georgio Nemer , Hatem Fessi , Catherine Charcosset
Journal of Pharmaceutical Sciences, 2019, 108 (8), pp.2708-2717. ⟨10.1016/j.xphs.2019.03.026⟩
Article dans une revue hal-02362258v1

Polymeric nanocapsules as drug carriers for sustained anticancer activity of calcitriol in breast cancer cells

Sabrina Nicolas , Marie-Alexandrine Bolzinger , Lars Petter Jordheim , Yves Chevalier , Hatem Fessi
International Journal of Pharmaceutics, 2018, 550 (1-2), pp.170-179. ⟨10.1016/j.ijpharm.2018.08.022⟩
Article dans une revue hal-02139822v1

Microencapsulation of rifampicin for the prevention of endophthalmitis: In vitro release studies and antibacterial assessment

Mi Yeon Lee , Sandrine Bourgeois , Eyad Almouazen , Jocelyne Pelletier , Francois Renaud
International Journal of Pharmaceutics, 2016, 505 (1-2), pp.262-270. ⟨10.1016/j.ijpharm.2016.03.026⟩
Article dans une revue hal-01814080v1

Antimicrobial nanocapsules: from new solvent-free process to in vitro efficiency

Damien Salmon , Julie Steelandt , Elodie Gilbert , Eyad Almouazen , Marek Haftek
International Journal of Nanomedicine, inPress, pp.4467
Article dans une revue hal-01958387v1

Antimicrobial nanocapsules: from new solvent-free process to in vitro efficiency

J. Steelandt , D. Salmon , E. Gilbert , E. Almouazen , F.N. Renaud
International Journal of Nanomedicine, 2014, 9, pp.4467-4474. ⟨10.2147/IJN.S64746⟩
Article dans une revue hal-01808035v1

Nano-encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation

Eyad Almouazen , Sandrine Bourgeois , Lars Petter Jordheim , Hatem Fessi , Stéphanie Briançon
Pharmaceutical Research, 2013, 30 (4), pp.1137 - 1146. ⟨10.1007/s11095-012-0949-4⟩
Article dans une revue hal-01895860v1

Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages

Eyad Almouazen , Sandrine Bourgeois , Ali Boussaïd , Pascale Valot , Celine Malleval
International Journal of Pharmaceutics, 2012, 430 (1-2), pp.207-215. ⟨10.1016/j.ijpharm.2012.03.025⟩
Article dans une revue hal-01958051v1

Nanoparticles and macrophages enhance anticancer activity of vitamin D3 metabolites

E. Almouazen , S. Bourgeois , L.P. Jordheim , H. Fessi , S. Briancon
9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2014, Lisbone, Portugal
Communication dans un congrès hal-02013719v1

Development of nanoparticle delivery system for oral vaccination of dogs

U. Benavides , E. Almouazen , S. Bourgeois , S. Azzouz , S. Briançon
Paravac Meeting, 2014, Cordoba, Spain
Communication dans un congrès hal-01958034v1

Développement de nanoparticules polymères pour le ciblage et la modulation des macrophages

Eyad Almouazen , Sandrine Bourgeois , Hatem Fessi , Stéphanie Briançon
JOURNÉE LYONNAISE AGENTS D’IMAGERIE " Nanoparticules multimodales pour le diagnostic et la thérapie, 2013, Lyon, France
Communication dans un congrès hal-01958037v1

Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages

E. Almouazen , S. Bourgeois , A. Boussaid , H. Fessi , S. Nataf
8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2012, Istanbul, Turkey
Communication dans un congrès hal-01958045v1

Development of 25-hydroxyvitamin D3 nanoparticles for application in chemotherapy: formulation study

E. Almouazen , S. Bourgeois , J. Honnorat , S. Briançon
8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2012, Istanbul, Turkey
Communication dans un congrès hal-01958046v1

Development of polymeric nanoparticles for targeting and modulating macrophage functions

E. Almouazen , S. Bourgeois , H. Fessi , S. Briançon
17ème Journée scientifique de l’EDISS, 2012, Lyon, France
Communication dans un congrès hal-01958047v1

Development of polymeric nanoparticles for targeting and modulating macrophage functions

E. Almouazen , S. Bourgeois , A. Boussaid , S. Briançon , S. Nataf
16ème Journée scientifique de l’EDISS, 2011, Lyon, France
Communication dans un congrès hal-01958057v1

Development of polymeric nanoparticles for modulating macrophage functions

Eyad Almouazen , S. Bourgeois , Ali Boussaïd , Pascale Valot , S. Briançon
2nd Conference Innovation in Drug Delivery:From preformulation to development through innovative evaluation process, 2010, Aix en Provence, France
Communication dans un congrès hal-01958063v1

Development of polymeric nanoparticles for modulating macrophage functions: an original strategy of cellular therapy for autoimmune diseases

Eyad Almouazen , S. Bourgeois , Ali Boussaïd , Pascale Valot , S. Briançon
7th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2010, Unknown, Malta
Communication dans un congrès hal-01958066v1