Eyad ALMOUAZEN
Présentation
Sep 2021 – Present: Principal Scientist, Drug Product Development
Virbac SA, Carros, France Lead R&D formulation unit, driving the development of biological drug products through the CMC phase. Apply QbD principles to enhance formulation performance and ensure robust, scalable manufacturing processes for liquid and lyophilized products. Spearhead 3 technical transfer projects, overseeing both internal and outsourced manufacturing to ensure seamless execution and compliance with regulatory standards. Sep 2014 – Sep 2021: Associated Professor
University Lyon 1 Teaching at Faculty of Pharmacy ISPB, Pharmaceutical and Cosmetic Technology Department Research at LAGEP‐ UMR CNRS 5007 – Pharmaceutical Engineering Team Design and development of innovative dosage forms for therapeutic applications: working on the elaboration of pharmaceutical formulations, the development of required analytical methods and the needed biological evaluations. 2012 – 2014 Temporary Assistant Professor
Faculty of Pharmacy ISPB, University Lyon 1, France Research: oral vaccine development for veterinary application 2009 – 2013 PhD student in Pharmaceutical Technology
LAGEP UMR CNRS 5007 and INSERM U1028, University Lyon1, France Thesis title: Development of polymeric nanoparticles for targeting and modulating macrophage functions.
-Retinoic acid and vitamin D3 encapsulation by nanoprecipitation
-Evaluation of nanoparticle uptake by macrophages in vitro and in vivo
-Assessment of therapeutical potential of developed nanoparticles Feb – July 2009 MSc Research internship
LAGEP UMR CNRS 5007 and INSERM U851, University Lyon1, France Project title: Use of nano-encapsulated haptens to improve the performance of skin sensitization non-animal test.
-Elaboration of hapten loaded polymeric nanoparticle.
-Test of nanoparticles on dendritic cells – T-cells co-culture. Mar – Sep 2008 Formulation Engineer
Laboratory of skin care development, L’Oreal-Paris, Chevilly-Larue, France Project title: New formulation development for cleansing application.
-Formulation and stability study of low viscosity emulsions. Jan – Juin 2007 R&D Engineer
Expanscience Laboratories, Damascus, Syria -Performed new control methods
-Validation of quality control protocols.
Compétences
Publications
Publications
Development of nanoparticle delivery system for oral vaccination of dogsParavac Meeting, 2014, Cordoba, Spain |
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Nanoparticles and macrophages enhance anticancer activity of vitamin D3 metabolites9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2014, Lisbone, Portugal |
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Développement de nanoparticules polymères pour le ciblage et la modulation des macrophagesJOURNÉE LYONNAISE AGENTS D’IMAGERIE " Nanoparticules multimodales pour le diagnostic et la thérapie, 2013, Lyon, France |
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Development of polymeric nanoparticles for targeting and modulating macrophage functions17ème Journée scientifique de l’EDISS, 2012, Lyon, France |
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Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2012, Istanbul, Turkey |
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Development of 25-hydroxyvitamin D3 nanoparticles for application in chemotherapy: formulation study8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2012, Istanbul, Turkey |
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Encapsulation of hydrophobic hapten enhances in vitro screening performance of non-soluble skin sensitizingSkin and Formulation 4th Symposium, Jun 2012, Lyon, France |
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Development of polymeric nanoparticles for targeting and modulating macrophage functions16ème Journée scientifique de l’EDISS, 2011, Lyon, France |
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Development of polymeric nanoparticles for modulating macrophage functions2nd Conference Innovation in Drug Delivery:From preformulation to development through innovative evaluation process, 2010, Aix en Provence, France |
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Development of polymeric nanoparticles for modulating macrophage functions: an original strategy of cellular therapy for autoimmune diseases7th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2010, Unknown, Malta |
Nanoparticules pour la liberation d’acides nucleiquesFrance, Patent n° : FR2112931A. 2021 |
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Développement de nanoparticules polymères pour le ciblage des macrophages et la modulation des leurs fonctions physiologiquesMédecine humaine et pathologie. Université Claude Bernard - Lyon I, 2013. Français. ⟨NNT : 2013LYO10121⟩ |