Fabien Pierrel

Documents

Publications

	COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells Ludovic Pelosi , Laura Morbiato , Arthur Burgardt , Fiorella Tonello , Abigail Bartlett Molecular Cell, 2024, 84 (5), pp.981-989. ⟨10.1016/j.molcel.2024.01.003⟩ Journal articles hal-04450030v1
	An organic O donor for biological hydroxylation reactions Katayoun Kazemzadeh Ferizhendi , Philippe Simon , Ludovic Pelosi , Emmanuel Séchet , Roache Arulanandam Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (13), pp.e2321242121. ⟨10.1073/pnas.2321242121⟩ Journal articles pasteur-04665824v1
	Structural Reconstruction of E. coli Ubi Metabolon Using an AlphaFold2-Based Computational Framework Romain Launay , Sophie-Carole Chobert , Sophie S Abby , Fabien Pierrel , Isabelle André Journal of Chemical Information and Modeling, 2024, 64 (13), pp.5175-5193. ⟨10.1021/acs.jcim.4c00304⟩ Journal articles hal-04662598v1
	Spatial heterogeneity for APRIL production by eosinophils in the small intestine Nathalie Sturm , Morgane Roger-Margueritat , Fabien Pierrel , Philippe Lehours , Muriel Genevay Journal of Leukocyte Biology, 2023, 113 (4), pp.376-382. ⟨10.1093/jleuko/qiad014⟩ Journal articles hal-04213714v1
	Diversification of ubiquinone biosynthesis via gene duplications, transfers, losses, and parallel evolution Katayoun Kazemzadeh , Ludovic Pelosi , Clothilde Chenal , Sophie-Carole Chobert , Mahmoud Hajj Chehade Molecular Biology and Evolution, 2023, 40 (10), pp.msad219. ⟨10.1093/molbev/msad219⟩ Journal articles hal-04256893v1
	Role of the Escherichia coli ubiquinone-synthesizing UbiUVT pathway in adaptation to changing respiratory conditions Rodrigo Arias-Cartin , Katayoun Kazemzadeh Ferizhendi , Emmanuel Séchet , Ludovic Pelosi , Corinne Loeuillet mBio, 2023, 14 (4), pp.e0329822. ⟨10.1128/mbio.03298-22⟩ Journal articles hal-04213722v2
	Towards Molecular Understanding of the Functional Role of UbiJ-UbiK2 Complex in Ubiquinone Biosynthesis by Multiscale Molecular Modelling Studies Romain Launay , Elin Teppa , Carla Martins , Sophie S Abby , Fabien Pierrel International Journal of Molecular Sciences, 2022, 23 (18), ⟨10.3390/ijms231810323⟩ Journal articles hal-03800688v1
	Rational Engineering of Non-Ubiquinone Containing Corynebacterium glutamicum for Enhanced Coenzyme Q10 Production Arthur Burgardt , Ludovic Pelosi , Mahmoud Hajj Chehade , Volker Wendisch , Fabien Pierrel Metabolites, 2022, 12 (5), pp.428. ⟨10.3390/metabo12050428⟩ Journal articles hal-03677651v1
	Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2 Vinzent Schulz , Somsuvro Basu , Sven-A. Freibert , Holger Webert , Linda Boss Nature Chemical Biology, 2022, ⟨10.1038/s41589-022-01159-4⟩ Journal articles hal-03836706v1
	Manganese-driven CoQ deficiency Jutta Diessl , Jens Berndtsson , Filomena Broeskamp , Lukas Habernig , Verena Kohler Nature Communications, 2022, 13 (1), pp.6061. ⟨10.1038/s41467-022-33641-x⟩ Journal articles hal-03836582v1
	Recent advances in the metabolic pathways and microbial production of coenzyme Q Fabien Pierrel , Arthur Burgardt , Jin-Ho Lee , Ludovic Pelosi , Volker Wendisch World Journal of Microbiology and Biotechnology, 2022, 38 (4), pp.58. ⟨10.1007/s11274-022-03242-3⟩ Journal articles hal-03677653v1
	Identification and characterization of a non-canonical menaquinone-linked formate dehydrogenase Rodrigo Arias-Cartin , Alexandre Uzel , Farida Seduk , Guillaume Gerbaud , Fabien Pierrel Journal of Biological Chemistry, 2022, 298 (2), pp.101384. ⟨10.1016/j.jbc.2021.101384⟩ Journal articles hal-03431446v1
	The [PSI + ] prion modulates cytochrome c oxidase deficiency caused by deletion of COX12 Pawan Kumar Saini , Hannah Dawitz , Andreas Aufschnaiter , Stanislav Bondarev , Jinsu Thom Molecular Biology of the Cell, 2022, ⟨10.1091/mbc.E21-10-0499⟩ Journal articles hal-03836554v1
	Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage Sheena Dass , Serena Shunmugam , Laurence Berry , Christophe-Sebastien Arnold , Nicholas Katris Nature Communications, 2021, 12, pp.2813. ⟨10.1038/s41467-021-22956-w⟩ Journal articles hal-03456819v1
	The biosynthetic pathway of ubiquinone contributes to pathogenicity of Francisella Running title: Ubiquinone and Francisella pathogenicity Katayoun Kazemzadeh , Mahmoud Hajj Chehade , Gautier Hourdoir , Camille Dorothée Brunet , Yvan Caspar Journal of Bacteriology, 2021, ⟨10.1128/JB.00400-21⟩ Journal articles hal-03357541v1
	The controversy on the ancestral arsenite oxidizing enzyme; deducing evolutionary histories with phylogeny and thermodynamics Julie Szyttenholm , Florence Chaspoul , Marielle Bauzan , Anne-Lise Ducluzeau , Mahmoud Hajj Chehade Biochimica biophysica acta (BBA) - Bioenergetics, 2020, 1861 (10), pp.148252. ⟨10.1016/j.bbabio.2020.148252⟩ Journal articles hal-02896357v1
	The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa Chau-Duy-Tam Vo , Julie Michaud , Sylvie Elsen , Bruno Faivre , Emmanuelle Bouveret Journal of Biological Chemistry, 2020, 295 (27), pp.9021-9032. ⟨10.1074/jbc.RA120.013748⟩ Journal articles pasteur-02746713v1
	Advances in bacterial pathways for the biosynthesis of ubiquinone Sophie S. Abby , Katayoun Kazemzadeh , Charles Vragniau , Ludovic Pelosi , Fabien Pierrel Biochimica biophysica acta (BBA) - Bioenergetics, 2020, 1861 (11), pp.148259. ⟨10.1016/j.bbabio.2020.148259⟩ Journal articles hal-02944115v1
	PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10 Cinzia Fino , Martin Vestergaard , Hanne Ingmer , Fabien Pierrel , Kenn Gerdes MicrobiologyOpen, 2020, ⟨10.1002/mbo3.1064⟩ Journal articles hal-02896344v1
	Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway Ludovic Pelosi , Chau-Duy-Tam Vo , Sophie Saphia Abby , Laurent Loiseau , Bérengère Rascalou mBio, 2019, 10 (4), ⟨10.1128/mBio.01319-19⟩ Journal articles hal-02183791v1
	Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6 Manuel Acosta Lopez , Eva Trevisson , Marcella Canton , Luis Vazquez-Fonseca , Valeria Morbidoni Oxidative Medicine and Cellular Longevity, 2019, 2019, pp.1-11. ⟨10.1155/2019/3904905⟩ Journal articles hal-02323996v1
	Vitamin K2 cannot substitute Coenzyme Q10 as electron carrier in the mitochondrial respiratory chain of mammalian cells Cristina Cerqua , Alberto Casarin , Fabien Pierrel , Luis Vazquez Fonseca , Giampiero Viola Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-43014-y⟩ Journal articles hal-02324041v1
	A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone Mahmoud Hajj Chehade , Ludovic Pelosi , Cameron David Fyfe , Laurent Loiseau , Bérengère Rascalou Cell Chemical Biology, 2019, 26 (4), pp.482-492.e7. ⟨10.1016/j.chembiol.2018.12.001⟩ Journal articles hal-02071798v1
	Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency Fabien Pierrel Frontiers in Physiology, 2017, 87, pp.80 - 80. ⟨10.3389/fphys.2017.00436⟩ Journal articles hal-01583835v1
	The COQ2 genotype predicts the severity of coenzyme Q 10 deficiency Maria Andrea Desbats , Valeria Morbidoni , Micol Silic-Benussi , Mara Doimo , Vincenzo Ciminale Human Molecular Genetics, 2017, 25 (19), pp.4256 - 4265. ⟨10.1093/hmg/ddw257⟩ Journal articles hal-01635280v1
	The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ Laurent Loiseau , Cameron Fyfe , Laurent Aussel , Mahmoud Hajj Chehade , Sara B. Hernández Journal of Biological Chemistry, 2017, 292 (28), pp.11937 - 11950. ⟨10.1074/jbc.M117.789164⟩ Journal articles hal-01615493v1
	Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6 Alexandre Ismail , Vincent Leroux , Myriam Smadja , Lucie Gonzalez , Murielle Lombard PLoS Computational Biology, 2016, 12 (1), pp.e1004690. ⟨10.1371/journal.pcbi.1004690⟩ Journal articles hal-01424489v1
	Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions Ludovic Pelosi , Anne-Lise Ducluzeau , Laurent Loiseau , Frédéric Barras , Dominique Schneider mSystems, 2016, 1 (4), pp.00091-16. ⟨10.1128/mSystems.00091-16⟩ Journal articles hal-01424513v1
	Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast Laurie-Anne Payet , Mélanie Leroux , John C. Willison , Akio Kihara , Ludovic Pelosi Cell Chemical Biology, 2016, 23 (10), pp.1241 - 1250. ⟨10.1016/j.chembiol.2016.08.008⟩ Journal articles hal-01424510v1
	Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity Jonathan a. Stefely , Floriana Licitra , Leila Laredj , Andrew g. Reidenbach , Zachary a. Kemmerer Molecular Cell, 2016, 63 (4), pp.608 - 620. ⟨10.1016/j.molcel.2016.06.030⟩ Journal articles hal-01424495v1
	Coq6 Is Responsible for the C4-deamination Reaction in Coenzyme Q Biosynthesis in Saccharomyces cerevisiae * Mohammad Ozeir , Ludovic Pelosi , Alexandre Ismail , Caroline Mellot-Draznieks , Marc Fontecave Journal of Biological Chemistry, 2015, ⟨10.1074/jbc.M115.675744⟩ Journal articles hal-01424487v1
	Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site Julia Rendon , Eric Pilet , Zeinab Fahs , Farida Seduk , Léa Sylvi Biochimica biophysica acta (BBA) - Bioenergetics, 2015, 1847 (8), pp.739-747. ⟨10.1016/j.bbabio.2015.05.001⟩ Journal articles hal-01429032v1
	ubiJ, a New Gene Required for Aerobic Growth and Proliferation in Macrophage, Is Involved in Coenzyme Q Biosynthesis in Escherichia coli and Salmonella enterica Serovar Typhimurium. Laurent Aussel , Laurent Loiseau , Mahmoud Hajj Chehade , Bérengère Pocachard , Marc Fontecave Journal of Bacteriology, 2014, 196 (1), pp.70-79. ⟨10.1128/JB.01065-13⟩ Journal articles hal-00917119v1
	Biosynthesis and physiology of coenzyme Q in bacteria. Laurent Aussel , Fabien Pierrel , Laurent Loiseau , Murielle Lombard , Marc Fontecave Biochimica biophysica acta (BBA) - Bioenergetics, 2014, 1837 (7), pp.1004-1011. ⟨10.1016/j.bbabio.2014.01.015⟩ Journal articles hal-01077983v1
	Three conserved histidyl residues contribute to mitochondrial iron transport through mitoferrins. Xavier Brazzolotto , Fabien Pierrel , Ludovic Pelosi Biochemical Journal, 2014, 460 (1), pp.79-89. ⟨10.1042/BJ20140107⟩ Journal articles hal-00961552v1
	A new gene involved in coenzyme Q biosynthesis in Escherichia coli: UbiI functions in aerobic C5-hydroxylation Mahmoud Hajj Chehade , Laurent Loiseau , Murielle Lombard , Ludovic Pecqueur , Alexandre Ismail Journal of Biological Chemistry, 2013, 288 (27), pp.20085-92. ⟨10.1074/jbc.M113.480368⟩ Journal articles hal-00904907v1
	Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency. Mara Doimo , Eva Trevisson , Rannar Airik , Marc Bergdoll , Carlos Santos-Ocaña BBA - Biochimica et Biophysica Acta, 2013, 1842 (1), pp.1-6. ⟨10.1016/j.bbadis.2013.10.007⟩ Journal articles hal-00904926v1
	In vivo accumulation of coenzyme Q biosynthetic intermediates and aminated analogs in the yeast Saccharomyces cerevisiae Mohammad Ozeir Ozeir , Letian X. Xie , Mahmoud Hajj Chehade , Jeniffer Y. Tang , Sylvie-Kieffer Jacquinod Biochimica biophysica acta (BBA) - Bioenergetics, 2012, 1817, pp.S92-S92. ⟨10.1016/j.bbabio.2012.06.249⟩ Journal articles hal-01236935v1
	Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway. Letian X Xie , Mohammad Ozeir , Jeniffer y Tang , Jia y Chen , Sylvie-Kieffer Jaquinod Journal of Biological Chemistry, 2012, 287 (28), pp.23571-81. ⟨10.1074/jbc.M112.360354⟩ Journal articles hal-00904902v1
	Coenzyme q biosynthesis: coq6 is required for the c5-hydroxylation reaction and substrate analogs rescue coq6 deficiency. Mohammad Ozeir , Ulrich Mühlenhoff , Holger Webert , Roland Lill , Marc Fontecave Chem Biol, 2011, 18 (9), pp.1134-42. ⟨10.1016/j.chembiol.2011.07.008⟩ Journal articles hal-00630764v1
	Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis. Fabien Pierrel , Olivier Hamelin , Thierry Douki , Sylvie Kieffer-Jaquinod , Ulrich Mühlenhoff Chem Biol, 2010, 17 (5), pp.449-59. ⟨10.1016/j.chembiol.2010.03.014⟩ Journal articles hal-00497916v1
	The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10. Megan Bestwick , Oleh Khalimonchuk , Fabien Pierrel , Dennis R Winge Molecular and Cellular Biology, 2010, 30 (1), pp.172-85. ⟨10.1128/MCB.00869-09⟩ Journal articles hal-00497920v1
	Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Ulrich Mühlenhoff , Sabine Molik , José R Godoy , Marta A Uzarska , Nadine Richter Cell Metab, 2010, 12 (4), pp.373-85. ⟨10.1016/j.cmet.2010.08.001⟩ Journal articles hal-00630763v1
	Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae. Oleh Khalimonchuk , Kevin Rigby , Megan Bestwick , Fabien Pierrel , Paul A Cobine Eukaryotic Cell, 2008, 7 (8), pp.1427-31. ⟨10.1128/EC.00132-08⟩ Journal articles hal-00375432v1
	Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein. Marjatta Son , Scot C Leary , Nadine Romain , Fabien Pierrel , Dennis R Winge Journal of Biological Chemistry, 2008, 283 (18), pp.12267-75. ⟨10.1074/jbc.M708523200⟩ Journal articles hal-00376153v1
	Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1. Fabien Pierrel , Oleh Khalimonchuk , Paul A Cobine , Megan Bestwick , Dennis R Winge Molecular and Cellular Biology, 2008, 28 (16), pp.4927-39. ⟨10.1128/MCB.00057-08⟩ Journal articles hal-00375430v1
	Metal Ion availability in mitochondria. Fabien Pierrel , Paul A Cobine , Dennis R Winge BioMetals, 2007, 20 (3-4), pp.675-82. ⟨10.1007/s10534-006-9052-9⟩ Journal articles hal-00375433v1
	Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly. Fabien Pierrel , Megan L Bestwick , Paul A Cobine , Oleh Khalimonchuk , Julia A Cricco EMBO Journal, 2007, 26 (20), pp.4335-46. ⟨10.1038/sj.emboj.7601861⟩ Journal articles hal-00374057v1
	MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters. Heather L. Hernandez , Fabien Pierrel , Eric Elleingand , Ricardo Garcia-Serres , Boi Hanh Huynh Biochemistry, 2007, 46, pp.5140-5147 Journal articles hal-00377635v1
	tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase. Carole Mathevon , Fabien Pierrel , Jean-Louis Oddou , Ricardo Garcia-Serres , Geneviève Blondin Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (33), pp.13295-300. ⟨10.1073/pnas.0704338104⟩ Journal articles hal-01069738v1
	The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding. Paul A Cobine , Fabien Pierrel , Scot C Leary , Florin Sasarman , Yih-Chern Horng Journal of Biological Chemistry, 2006, 281 (18), pp.12270-6. ⟨10.1074/jbc.M600496200⟩ Journal articles hal-00376137v1
	Copper trafficking to the mitochondrion and assembly of copper metalloenzymes. Paul A Cobine , Fabien Pierrel , Dennis R Winge Biochimica et Biophysica Acta - Molecular Cell Research, 2006, 1763 (7), pp.759-72. ⟨10.1016/j.bbamcr.2006.03.002⟩ Journal articles hal-00376149v1
	Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase. Paul A Cobine , Fabien Pierrel , Megan L Bestwick , Dennis R Winge Journal of Biological Chemistry, 2006, 281 (48), pp.36552-9. ⟨10.1074/jbc.M606839200⟩ Journal articles hal-00376121v1

	A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism Felix J Elling , Fabien Pierrel , Sophie-Carole Chobert , Sophie S Abby , Thomas W Evans 2024 Preprints, Working Papers, ... hal-04679398v1
	The [PSI+] prion and HSP104 modulate cytochrome c oxidase deficiency caused by deletion of COX12 Pawan Kumar Saini , Hannah Dawitz , Andreas Aufschnaiter , Jinsu Thomas , Amélie Amblard 2021 Preprints, Working Papers, ... hal-03402829v1

Fabien Pierrel

Publications

COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells

An organic O donor for biological hydroxylation reactions

Structural Reconstruction of E. coli Ubi Metabolon Using an AlphaFold2-Based Computational Framework

Spatial heterogeneity for APRIL production by eosinophils in the small intestine

Diversification of ubiquinone biosynthesis via gene duplications, transfers, losses, and parallel evolution

Role of the Escherichia coli ubiquinone-synthesizing UbiUVT pathway in adaptation to changing respiratory conditions

Towards Molecular Understanding of the Functional Role of UbiJ-UbiK2 Complex in Ubiquinone Biosynthesis by Multiscale Molecular Modelling Studies

Rational Engineering of Non-Ubiquinone Containing Corynebacterium glutamicum for Enhanced Coenzyme Q10 Production

Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2

Manganese-driven CoQ deficiency

Recent advances in the metabolic pathways and microbial production of coenzyme Q

Identification and characterization of a non-canonical menaquinone-linked formate dehydrogenase

The [PSI + ] prion modulates cytochrome c oxidase deficiency caused by deletion of COX12

Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage

The biosynthetic pathway of ubiquinone contributes to pathogenicity of Francisella Running title: Ubiquinone and Francisella pathogenicity

The controversy on the ancestral arsenite oxidizing enzyme; deducing evolutionary histories with phylogeny and thermodynamics

The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa

Advances in bacterial pathways for the biosynthesis of ubiquinone

PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10

Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway

Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6

Vitamin K2 cannot substitute Coenzyme Q10 as electron carrier in the mitochondrial respiratory chain of mammalian cells

A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone

Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency

The COQ2 genotype predicts the severity of coenzyme Q 10 deficiency

The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ

Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6

Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions

Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity

Coq6 Is Responsible for the C4-deamination Reaction in Coenzyme Q Biosynthesis in Saccharomyces cerevisiae *

Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site

ubiJ, a New Gene Required for Aerobic Growth and Proliferation in Macrophage, Is Involved in Coenzyme Q Biosynthesis in Escherichia coli and Salmonella enterica Serovar Typhimurium.

Biosynthesis and physiology of coenzyme Q in bacteria.

Three conserved histidyl residues contribute to mitochondrial iron transport through mitoferrins.

A new gene involved in coenzyme Q biosynthesis in Escherichia coli: UbiI functions in aerobic C5-hydroxylation

Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency.

In vivo accumulation of coenzyme Q biosynthetic intermediates and aminated analogs in the yeast Saccharomyces cerevisiae

Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.

Coenzyme q biosynthesis: coq6 is required for the c5-hydroxylation reaction and substrate analogs rescue coq6 deficiency.

Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis.

The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10.

Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster.

Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae.

Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein.

Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1.

Metal Ion availability in mitochondria.

Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly.

MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters.

tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase.

The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding.

Copper trafficking to the mitochondrion and assembly of copper metalloenzymes.

Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase.

A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism

The [PSI+] prion and HSP104 modulate cytochrome c oxidase deficiency caused by deletion of COX12