FB

Fabienne Bardou

50 %
Libre accès
18
Documents
Affiliations actuelles
  • Communauté d'universités et établissements de Toulouse (Comue de Toulouse)
  • Université Toulouse III - Paul Sabatier (UT3)
  • Institut de pharmacologie et de biologie structurale (IPBS)
Contact

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

biochimie, microbiologie

Publications

Publications

Towards a better understanding of the Mycobacterium tuberculosis FAS-II system

Yasmine Hamchaoui , Pascaline Bories , Elorri Drogon , Manuelle Ducoux-Petit , Samuel Tranier et al.

•MIRA Franco-Indian Workshop 2025. Infectious Diseases & Microbial Resistance., May 2025, Toulouse, France

Poster de conférence hal-05513064v1

The HadB-HadD complex from the fatty acid synthase type II system, is important for mycolic acid biosynthesis and mycobacterial fitness, and for Mycobacterium tuberculosis virulence

Manuelle Ducoux-Petit , Pascaline Bories , Julie Rima , Samuel Tranier , Julien Marcoux et al.

EuPA 2025: Conference of the European Proteomics Association, Jun 2025, Saint-Malo, France

Poster de conférence hal-05513467v1

The HadB-HadD complex, from the fatty acid synthase type II system, is important for biosynthesis, fitness and virulence of Mycobacterium smegmatis and Mycobacterium tuberculosis

Pascaline Bories , Julie Rima , Samuel Tranier , Julien Marcoux , Yasmina Grimoire et al.

HUPO 2024: 23rd Human Proteome Organization World Congress, Oct 2024, Dresde, Germany

Poster de conférence hal-05513441v1

Characterization of protein-protein interaction inhibitors targeting the FAS-II system of Mycobacterium tuberculosis

Yasmine Hamchaoui , Samuel Tranier , Pascaline Bories , Julien Marcoux , Philippe Roche et al.

3rd Integrative Structural Biology Meeting (BSI-2023), Nov 2023, Marseille, France

Poster de conférence hal-05513357v1

Structure-function relationships of HadBD dehydratase from Mycobacterium tuberculosis

Pascaline Bories , Julie Rima , Samuel Tranier , Julien Marcoux , Hedia Marrakchi et al.

MYCODAYS 2022, Jun 2022, Lyon, France

Poster de conférence hal-05513303v1

Structure-function relationships of HadBD dehydratase from Mycobacterium tuberculosis

Pascaline Bories , Julie Rima , Samuel Tranier , Julien Marcoux , Hedia Marrakchi et al.

MYCODAYS-Société Française de Microbiologie (SFM), Jun 2022, Lyon, France

Poster de conférence hal-03820111v1
Deposit thumbnail

HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II : A singular structure for a unique function

Pascaline Bories , Julie Rima , Samuel Tranier , Julien Marcoux , Yasmina Grimoire et al.

Protein Science, 2024, 33 (4), pp.e4964. ⟨10.1002/pro.4964⟩

Article dans une revue hal-04764850v1
Deposit thumbnail

HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness

Cyril Lefebvre , Richard Boulon , Manuelle Ducoux , Sabine Gavalda , Françoise Laval et al.

Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-24380-5⟩

Article dans une revue hal-02179486v1
Deposit thumbnail

Functional reconstitution of the Mycobacterium tuberculosis long‐chain acyl‐CoA carboxylase from multiple acyl‐CoA subunits

Bernardo Bazet Lyonnet , Lautaro Diacovich , Gabriela Gago , Lucie Spina , Fabienne Bardou et al.

FEBS Journal, 2017, 284 (7), pp.1110-1125. ⟨10.1111/febs.14046⟩

Article dans une revue hal-04023585v1
Deposit thumbnail

Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis.

Nguyen-Hung Le , Virginie Molle , Nathalie Eynard , Mathieu Miras , Alexandre Stella et al.

Journal of Biological Chemistry, 2016, 291 (43), pp.22793-22805. ⟨10.1074/jbc.M116.748053⟩

Article dans une revue hal-01604694v1
Deposit thumbnail

The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria

Sabine Gavalda , Fabienne Bardou , Françoise Laval , Cécile Bon , Wladimir Malaga et al.

Chemistry and Biology, 2014, 21 (12), pp.1660 - 1669. ⟨10.1016/j.chembiol.2014.10.011⟩

Article dans une revue hal-03002982v1

Synthesis, biological activity, and evaluation of the mode of action of novel antitubercular benzofurobenzopyrans substituted on A ring.

Aikaterini Termentzi , Inana Khouri , Thomas Gaslonde , Soizic Prado , Brigitte Saint-Joanis et al.

European Journal of Medicinal Chemistry, 2010, 45 (12), pp.5833-47. ⟨10.1016/j.ejmech.2010.09.048⟩

Article dans une revue istex pasteur-00542697v1
Deposit thumbnail

The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids in Mycobacterium tuberculosis

Sabine Gavalda , Mathieu Léger , Benoît van Der Rest , Alexandre Stella , Fabienne Bardou et al.

Journal of Biological Chemistry, 2009, 284 (29), pp.19255-19264. ⟨10.1074/jbc.M109.006940⟩

Article dans une revue hal-03003050v1
Deposit thumbnail

S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor ofMycobacterium tuberculosisMycolic Acid Methyltransferases

Julien Vaubourgeix , Fabienne Bardou , Fanny Boissier , Sylviane Julien , Patricia Constant et al.

Journal of Biological Chemistry, 2009, 284, pp.19321 - 19330. ⟨10.1074/jbc.m809599200⟩

Article dans une revue hal-03003382v1
Deposit thumbnail

Further Insight into S-Adenosylmethionine-dependent Methyltransferases: STRUCTURAL CHARACTERIZATION OF Hma, AN ENZYME ESSENTIAL FOR THE BIOSYNTHESIS OF OXYGENATED MYCOLIC ACIDS IN MYCOBACTERIUM TUBERCULOSIS

Fanny Boissier , Fabienne Bardou , Valérie Guillet , Sandrine Uttenweiler-Joseph , Mamadou Daffé et al.

Journal of Biological Chemistry, 2006, 281 (7), pp.4434-4445. ⟨10.1074/jbc.M510250200⟩

Article dans une revue hal-03003456v1

Evidence that the activation of substrates used for the condensation leading to the synthesis of Mycolic acids required the acyl-AMP ligase FadD32 and an AccD4-containing Acyl-CoA carboxylase

D. Portevin , De Souza-d'Auria C. , H. Montrozier , Houssin Ch. , A. Stella et al.

Journal of Biological Chemistry, 2005, 280 (10), pp.8862-8874

Article dans une revue hal-00078690v1

Extracellular and surface-exposed polysaccharides of non-tuberculous mycobacteria

Anne Lemassu , Annick Ortalo-Magné , Fabienne Bardou , Gaby Silve , Marie-Antoinette Lanéelle et al.

Microbiology, 1996, 142 (6), pp.1513-1520. ⟨10.1099/13500872-142-6-1513⟩

Article dans une revue hal-04025839v1

Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species

A Ortalo-Magné , Anne Lemassu , M Lanéelle , F Bardou , G Silve et al.

Journal of Bacteriology, 1996, 178 (2), pp.456-461. ⟨10.1128/jb.178.2.456-461.1996⟩

Article dans une revue hal-04021484v1