Fabienne MEGGETTO

28
Documents

Publications

Publications

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A strong internal promoter drives massive expression of YEATS‐domain devoid MLLT3 transcripts in HSC and most lethal AML

Chloé Bessière , Ahmed Zamani , Romain Pfeifer , Sandra Dailhau , Camille Marchet et al.

Cancer Communications, 2025, ⟨10.1002/cac2.12650⟩

Article dans une revue hal-04891593v1
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Differential prognostic values of the three AKT isoforms in acute myeloid leukemia

Eulalie Corre , Cécile Soum , Romain Pfeifer , Chloé Bessière , Sandra Dailhau et al.

Scientific Reports, 2024, 14 (1), pp.7070. ⟨10.1038/s41598-024-57578-x⟩

Article dans une revue hal-04746886v1

Brigatinib in ALK-Positive ALCL after Failure of Brentuximab Vedotin

Layla Veleanu , Laurence Lamant , David Sibon , Ambroise Marçais , Julie Bruneau et al.

New England Journal of Medicine, 2024, 390, pp.2129 - 2130. ⟨10.1056/nejmc2402419⟩

Article dans une revue hal-04755662v1
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From normal hematopoiesis to malignancies: Highlights from the 2021 Meeting of the Club Hematopoiesis and Oncogenesis

Marie-Bérengère Troadec , Françoise Porteu , Marie-Laure Arcangeli , Adlen Foudi , Dominique Bluteau et al.

Bulletin du Cancer, 2023, 110 (3), pp.331-335. ⟨10.1016/j.bulcan.2022.12.013⟩

Article dans une revue hal-04266637v1
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Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN

Steffen Fuchs , Clara Danßmann , Filippos Klironomos , Annika Winkler , Jörg Fallmann et al.

Nature Communications, 2023, 14 (1), pp.3936. ⟨10.1038/s41467-023-38747-4⟩

Article dans une revue hal-04746875v1
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Generation of full-length circular RNA libraries for Oxford Nanopore long-read sequencing

Steffen Fuchs , Loélia Babin , Elissa Andraos , Chloé Bessiere , Semjon Willier et al.

PLoS ONE, 2022, 17 (9), pp. e0273253. ⟨10.1371/journal.pone.0273253⟩

Article dans une revue hal-03773269v1
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De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

Loélia Babin , Alice Darchen , Elie Robert , Zakia Aid , Rosalie Borry et al.

Molecular Cancer, 2022, 21 (1), pp.65. ⟨10.1186/s12943-022-01520-0⟩

Article dans une revue mnhn-03868576v1
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A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA

Morgane Gourvest , Etienne de Clara , Hsin-Chieh Wu , Christian Touriol , Fabienne Meggetto et al.

Leukemia, 2021, 35 (10), pp.2784 - 2798. ⟨10.1038/s41375-021-01307-0⟩

Article dans une revue hal-03383458v1
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From circRNAs to fusion circRNAs in hematological malignancies

Loelia Babin , Elissa Andraos , Steffen Fuchs , Stéphane Pyronnet , Erika Brunet et al.

JCI Insight, 2021, 6 (21), ⟨10.1172/jci.insight.151513⟩

Article dans une revue hal-03826890v2
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Gene Expression Signature Associated with Clinical Outcome in ALK-Positive Anaplastic Large Cell Lymphoma

Daugrois Camille , Bessiere Chloé , Dejean Sébastien , Anton Leberre Véronique , Commes Thérèse et al.

Cancers, 2021, 13 (21), ⟨10.3390/cancers13215523⟩

Article dans une revue hal-03450450v1
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High Levels of miR-7-5p Potentiate Crizotinib-Induced Cytokilling and Autophagic Flux by Targeting RAF1 in NPM-ALK Positive Lymphoma Cells

Domenico Sorrentino , Julie Frentzel , Géraldine Mitou , Rafael B Blasco , Avédis Torossian et al.

Cancers, 2020, 12 (10), pp.2951. ⟨10.3390/cancers12102951⟩

Article dans une revue hal-04822934v1

ALK-transformed mature T lymphocytes restore early thymus progenitor features

Annabelle Congras , Coralie Hoareau-Aveilla , Nina Caillet , Marie Tosolini , Patrick Villarese et al.

Journal of Clinical Investigation, 2020, 130 (12), pp.6395-6408. ⟨10.1172/JCI134990⟩

Article dans une revue hal-03073841v1

ALK-positive histiocytosis associated with chronic lymphocytic leukaemia/small lymphocytic lymphoma: a multitarget response under ibrutinib

Charlotte Syrykh , Loic Ysebaert , Sarah Péricart , Solène Evrard , Fabienne Meggetto et al.

Virchows Archiv, 2020, ⟨10.1007/s00428-020-02937-y⟩

Article dans une revue hal-03073859v1
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MiR-497 suppresses cycle progression through an axis involving CDK6 in ALK-positive cells.

Coralie Hoareau-Aveilla , Cathy Quelen , Annabelle Congras , Nina Caillet , Delphine Labourdette et al.

Haematologica, 2019, 104 (2), pp.347-359. ⟨10.3324/haematol.2018.195131⟩

Article dans une revue hal-01951558v1
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Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma

Stefen Fuchs , J Naderi , Fabienne Meggetto

International Journal of Molecular Sciences, 2019, 20 (9), pp.2150. ⟨10.3390/ijms20092150⟩

Article dans une revue hal-02359846v1
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Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells

Annabelle Congras , Nina Caillet , Nouritza Torossian , Cathy Quelen , Camille Daugrois et al.

Oncotarget, 2018, 9 (18), ⟨10.18632/oncotarget.24465⟩

Article dans une revue hal-02359856v1

Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth

Coralie Hoareau-Aveilla , Thibaud Valentin , Camille Daugrois , Cathy Quelen , Géraldine Mitou et al.

Journal of Clinical Investigation, 2015, 125 (9), pp.3505--3518. ⟨10.1172/JCI78488⟩

Article dans une revue hal-01614947v1

Inhibition of Rac controls NPM-ALK-dependent lymphoma development and dissemination.

A. Colomba , Sylvie Giuriato , Emilie Dejean , K. Thornber , Georges Delsol et al.

Blood Cancer Journal, 2011, 1 (6), pp.e21. ⟨10.1038/bcj.2011.19⟩

Article dans une revue inserm-00726858v1

A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor.

Sophie Chabot , Nabila Jabrane-Ferrat , Karine Bigot , Julie Tabiasco , Alexandra Provost et al.

Journal of Experimental Medicine, 2011, 208 (5), pp.973-86. ⟨10.1084/jem.20100810⟩

Article dans une revue hal-00640905v1

Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas.

E. Dejean , M. H. Renalier , M. Foisseau , X. Agirre , Nicole Joseph et al.

Leukemia, 2011, epub ahead of print. ⟨10.1038/leu.2011.168⟩

Article dans une revue hal-00611903v1

MiR-29a down-regulation in ALK-positive anaplastic large cell lymphomas contributes to apoptosis blockade through MCL-1 overexpression.

Cécile Desjobert , Marie-Hélène Renalier , Julie Bergalet , Emilie Dejean , Nicole Joseph et al.

Blood, 2011, 117 (24), pp.6627-37. ⟨10.1182/blood-2010-09-301994⟩

Article dans une revue hal-00611908v1

Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia.

Sylvie Giuriato , Marianne Foisseau , Emilie Dejean , Dean W Felsher , Talal Al Saati et al.

Blood, 2010, 115 (20), pp.4061-70. ⟨10.1182/blood-2008-06-163386⟩

Article dans une revue hal-00502987v1

Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway.

Nathalie Faumont , Christophe Le Clorennec , Pierre Teira , Gauthier Goormachtigh , Jean Coll et al.

Cancer Research, 2009, 69 (12), pp.5177-85. ⟨10.1158/0008-5472.CAN-08-2866⟩

Article dans une revue hal-00397988v1

Comparative analysis of oncogenic properties and nuclear factor-kappaB activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes.

Nathalie Faumont , Aurélie Chanut , Alan Benard , Nadine Cogné , Georges Delsol et al.

Haematologica, 2009, 94 (3), pp.355-63. ⟨10.3324/haematol.13269⟩

Article dans une revue hal-00397989v1

Development of a Conditional Bioluminescent Transplant Model for TPM3-ALK-Induced Tumorigenesis as a Tool to Validate ALK-Dependent Cancer Targeted Therapy.

Sylvie Giuriato , Nathalie Faumont , Emilie Bousquet , Marianne Foisseau , Anne Bibonne et al.

Cancer Biology and Therapy, 2007, 6 (8), pp.1318-23. ⟨10.4161/cbt.6.8.4508⟩

Article dans une revue hal-00170626v1

Evidence for early infection of nonneoplastic natural killer cells by Epstein-Barr virus.

Pascal Trempat , Julie Tabiasco , Pascale Andre , Nathalie Faumont , Fabienne Meggetto et al.

Journal of Virology, 2002, pp.11139-11142. ⟨10.1128/JVI.76.21.11139-11142.2002⟩

Article dans une revue hal-01759549v1

Human Monocytic Cell Lines Transformed In Vitro by Epstein-Barr Virus Display a Type II Latency and LMP-1-Dependent Proliferation

Eric Masy , Eric Adriaenssens , Claire Montpellier , Pascale Crépieux , Alexandra Mougel et al.

Journal of Virology, 2002, 76 (13), pp.6460-6472. ⟨10.1128/jvi.76.13.6460-6472.2002⟩

Article dans une revue hal-03104020v1