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Mechanistic study of the differences in lactic acid bacteria resistance to freeze- or spray-drying and storage
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Carolina Schebor
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Investigation of Freezing and Freeze-Drying for Preserving and Re-Using a Whole Microbial Cheese Community
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Chickpeas’ Cooking Wastewater as an Alternative Source of Galacto-Oligosaccharides for Improving the Freeze-Dried Resistance of Lactic Acid Bacteria
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Pascale Lieben
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Sarrah Ghorbal
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Use of Legume Wastewater Extracts on the Storage Stability of Freeze-Dried Lactiplantibacillus plantarum WCFS1
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Preservation of Bacillus subtilis’ cellular liquid state at deep sub-zero temperatures in perchlorate brines
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Fernanda Fonseca
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Charles S Cockell
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Multiobjective optimization of frozen and freeze-dried Lactobacillus delbrueckii subsp. bulgaricus CFL1 production via the modification of fermentation conditions
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Yann Gohon
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Membrane lipid composition of Carnobacterium maltaromaticum CNCM I-3298, a highly cryoresistant lactic bacterium
Ha Phuong Ta
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C. Clarisse
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E. Maes
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N. Yamakawa
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Y. Guérardel
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Insights into the mechanisms of L. salivarius CECT5713 resistance to freeze-dried storage
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Sonia Campoy
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Journal articles
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Insights into lactic acid bacteria cryoresistance using FTIR micro-spectroscopy
Amélie Girardeau
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Pascale Lieben
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Ligilactobacillus salivarius functionalities, applications, and manufacturing challenges
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S. Campoy
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M. Olivares
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F. Fonseca
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Use of 3D mathematical modelling to understand the heat transfer mechanisms during freeze-drying using high-throughput vials
Juan Patricio Buceta
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Stephanie Passot
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Bernadette Scutellà
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Erwan Bourlés
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Fernanda Fonseca
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Effect of protective agents on the storage stability of freeze‑dried Ligilactobacillus salivarius CECT5713
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Stéphanie Passot
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Sonia Campoy
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Monica Olivares
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Fernanda Fonseca
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Dynamic Modeling of Carnobacterium Maltaromaticum CNCM I-3298 Growth and Metabolite Production and Model-Based Process Optimization
Cristian Puentes
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Amélie Girardeau
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Stephanie Passot
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Fernanda Fonseca
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Ioan-Cristian Trelea
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Heat Transfer During Freeze-Drying Using a High-throughput vial System in view of Process Scale-up to Serum vials
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Ioan Trelea
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Bernadette Scutellà
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Erwan Bourlés
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Fernanda Fonseca
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The transfer temperature from slow cooling to cryogenic storage is critical for optimal recovery of cryopreserved mammalian cells
Peter Kilbride
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Julie Meneghel
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John Morris
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FTIR micro-spectroscopy using synchrotron-based and thermal source-based radiation for probing live bacteria
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Stéphane Lefrançois
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Pascale Lieben
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Highlighting Protective Effect of Encapsulation on Yeast Cell Response to Dehydration Using Synchrotron Infrared Microspectroscopy at the Single-Cell Level
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Stéphane Guyot
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Caroline Pénicaud
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Stéphanie Passot
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Christophe Sandt
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FTIR micro-spectroscopy using synchrotron-based and thermal source-based radiation for probing live bacteria
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Stéphane Lefrançois
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The Impact of varying cooling and thawing rates on the quality of cryopreserved human peripheral blood t cells
Jasmin Baboo
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Peter Kilbride
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Mike Delahaye
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Stuart Milne
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Fernanda Fonseca
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Influence of culture conditions on the technological properties of Carnobacterium maltaromaticum CNCM I-3298 starters
Amélie Girardeau
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C. Puentes
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S. Keravec
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P. Peteuil
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Ioan-Cristian Trelea
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Écoconception des aliments, bioproduits, bioprocédés et procédés alimentaires
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Fernanda Fonseca
Techniques de l'Ingénieur, 2019
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Relating transformation process, eco-design, composition and sensory quality in cheeses using PO2 ontology
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Liliana Ibanescu
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Thomas Allard
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Fernanda Fonseca
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Stephane S. Dervaux
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Physical events occurring during the cryopreservation of immortalized human T cells
Julie Meneghel
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Peter Kilbride
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John G. Morris
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Fernanda Fonseca
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A Guide for Ex Vivo Handling and storage of stool samples Intended for Fecal Microbiota transplantation
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Anne-Laure Abraham
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Olivier David
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Audrey Chapron
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Factors influencing the membrane fluidity and the impact on production of lactic acid bacteria starters
Fernanda Fonseca
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Caroline Pénicaud
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E. Elizabeth Tymczyszyn
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Andrea Gómez-Zavaglia
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Determination of the dried product resistance variability and its influence on the product temperature in pharmaceutical freeze-drying
Bernadette Scutella
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Ioan-Cristian Trelea
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Erwan Bourlés
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Fernanda Fonseca
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Stéphanie Passot
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Effect of freeze-dryer design on heat transfer variability investigated using a 3D mathematical model
B. Scutellà
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E. Bourlés
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Artemio Plana-Fattori
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F. Fonseca
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D. Flick
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Life cycle assessment of the production of stabilized lactic acid bacteria for the environmentally-friendly preservation of living cells
Caroline Pénicaud
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Vincent Monclus
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Fernanda Fonseca
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Nouveaux dispositifs médicaux et nouveau procédé de fabrication pour un transfert de microbiote fécal par voie rectale, sans risque, standardisé et prêt à l’emploi
Jean-François Dubuisson
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Catherine Juste
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Fernanda Fonseca
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Patricia Lepage
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Christel Béra-Maillet
Journal de Pharmacie Clinique, 2018, 37 (2), pp.73-83
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The virtual food system: Innovative models and experiential feedback in technologies for winemaking, the cereals chain, food packaging and eco-designed starter production
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Violaine Athès
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Patrice Buche
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Guy Della Valle
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Vincent Farines
Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2018, Food Science and Technology in France: INRA’s contribution to this area, 46, pp.54-64. ⟨10.1016/j.ifset.2017.10.006⟩
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How vial geometry variability influences heat transfer and product temperature during freeze-drying
Bernadette Scutella
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Stéphanie Passot
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Erwan Bourlés
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Fernanda Fonseca
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Ioan-Cristian Trelea
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Subcellular membrane fluidity of Lactobacillus delbrueckii subsp. bulgaricus under cold and osmotic stress
Julie Meneghel
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Stéphanie Passot
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Stéphanie Cenard
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Matthieu Refregiers
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Frédéric Jamme
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Biophysical characterization of the Lactobacillus delbrueckii subsp. bulgaricus membrane during cold and osmotic stress and its relevance for cryopreservation
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Stéphanie Passot
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Sébastien Dupont
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Fernanda Fonseca
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Understanding the responses of Saccharomyces cerevisiae yeast strain during dehydration processes using synchrotron infrared spectroscopy
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Stéphane Guyot
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Caroline Pénicaud
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S. Passot
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C. Sandt
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3D mathematical modelling to understand atypical heat transfer observed in vial freeze-drying
Bernadette Scutellà
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Artemio Plana-Fattori
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Stéphanie Passot
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E Bourlès
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Fernanda Fonseca
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Draft Genome Sequence of Lactobacillus delbrueckii subsp. bulgaricus CFL1, a Lactic Acid Bacterium Isolated from French Handcrafted Fermented Milk
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Eric Dugat-Bony
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Françoise Irlinger
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Valentin Loux
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Marie Vidal
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Dynamic modelling of the secondary drying stage of freeze-drying reveals distinct desorption kinetics for bound water
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Fernanda Fonseca
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Stéphanie Passot
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Protection of yeast cells in micro-organized shells of natural polyelectrolytes during drying process
Thanh Dat Nguyen
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Stéphane Guyot
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Christophe Sandt
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Caroline Pénicaud
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Stéphanie Passot
STP Pharma Pratiques, 2016, 26 (2), pp.133
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Determination of Intracellular Vitrification Temperatures for Unicellular Micro Organisms under Conditions Relevant for Cryopreservation
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Julie Meneghel
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Stéphanie Cenard
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Stéphanie Passot
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G. John Morris
Journal articles
hal-01565156v1
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Draft Genome Sequence of Lactobacillus delbrueckii subsp. bulgaricus CFL1, a Lactic Acid Bacterium Isolated from French Handcrafted Fermented Milk
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Eric Dugat-Bony
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Françoise Irlinger
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Valentin Loux
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Marie Vidal
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Cyclopropanation of unsaturated fatty acids and membrane rigidification improve the freeze-drying resistance of Lactococcus lactis subsp lactis TOMSC161
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Marielle Bouix
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Stéphanie Passot
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Caroline Pénicaud
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Helene Beinsteiner
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A binary gas transport model Improves the prediction of mass transfer in freeze drying
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Fernanda Fonseca
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Denis Flick
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Understanding the cryotolerance of lactic acid bacteria using combined synchrotron infrared and fluorescence microscopies
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Julie Gautier
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Frédéric Jamme
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Stéphanie Cenard
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Paul Dumas
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Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis subsp. lactis TOMSC161, Isolated from a Nonscalded Curd Pressed Cheese
Hélène Velly
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Pierre Renault
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Anne-Laure Abraham
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Valentin Loux
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Agnes Delacroix-Buchet
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Physiological and biochemical responses of Yarrowia lipolytica to dehydration induced by air-drying and freezing
Caroline Pénicaud
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Sophie Landaud-Liautaud
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Frederic Jamme
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Pauline Talbot
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Marielle Bouix
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Cell growth and resistance of Lactococcus lactis subsp lactis TOMSC161 following freezing, drying and freeze-dried storage are differentially affected by fermentation conditions
Helene Velly
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Fernanda Fonseca
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Stéphanie Passot
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Agnes Delacroix-Buchet
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Marielle Bouix
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Synchrotron UV fluorescence microscopy for determining membrane fluidity modification of single bacteria with temperatures
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Frederic Jamme
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M. Refregiers
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Julie J. Gautier
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Stéphanie Cenard
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A low membrane lipid phase transition temperature is associated with a high cryotolerance of [i]Lactobacillus delbrueckii[/i] subspecies [i]bulgaricus[/i] CFL1
Julie J. Gautier
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Stéphanie S. Passot
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Caroline Pénicaud
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Herve H. Guillemin
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Stéphanie S. Cenard
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A low temperature limit for life on Earth
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Fernanda Fonseca
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Benjamin J. Murray
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Elizabeth Acton
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A low temperature limit for life on earth
A. Clark
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F. Fonseca
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B.J. Murray
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E. Acton
PLoS ONE, 2013, in press
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Freezing injury: the special case of the sperm cell
G.J. Morris
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E. Acton
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B. Murray
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F. Fonseca
Cryobiology, 2012, 64, pp.71--80
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Critical water activity and amorphous state for optimal preservation of lyophilised lactic acid bacteria
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Stéphanie Cenard
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Inès Douania
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Ioan Cristian Trelea
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Fernanda Fonseca
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Freezing injury: The special case of the sperm cell
G. John Morris
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Elizabeth Acton
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Benjamin J. Murray
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Fernanda Fonseca
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Toward Optimal Operation Conditions of Freeze-Drying Processes via a Multilevel Approach
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Stéphanie Passot
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Fernanda Fonseca
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Ioan-Cristian Trelea
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Antonio A. Alonso
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Freezing protocol effect on quality properties of fruit tissue according to the fruit, the variety and the stage of maturity
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Morgane Citeau
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Michele Marin
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Effect of controlled ice nucleation on primary drying stage and protein recovery in vials cooled in a modified freeze-dryer
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Ioan-Cristian Trelea
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Michele Marin
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Miquel Galan
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Model for Heat and Mass Transfer in Freeze-Drying of Pellets
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Stephanie Passot
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Michele Marin
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Changes in texture, cellular structure and cell wall composition in apple tissue as a result of freezing
Sophie Chassagne
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Cécile Poirier
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Marie Francoise Devaux
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Fernanda Fonseca
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Marc Lahaye
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An Interactive Tool for the Optimization of Freeze-Drying Cycles Based on Quality Criteria
Ioan-Cristian Trelea
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Stéphanie Passot
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Fernanda Fonseca
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Michele Marin
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Rapidly cooled horse spermatozoa: loss of viability is due to osmotic imbalance during thawing, not intracellular ice formation
G. John Morris
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J. E. Green
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B. W. W. Grout
Theriogenology, 2007, 68 (5), pp.804-812
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Effect of product temperature applied during primary drying on the long-term stability of lyophilized proteins
Stéphanie S. Passot
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Naziha Barbouche
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Pharmaceutical Development and Technology, 2007, 12 (6), pp.543-53
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Stabilization of frozen Lactobacillus delbrueckii subsp. bulgaricus in glycerol suspensions : freezing kinetics and storage temperature effects
Fernanda Fonseca
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Michèle Marin
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G. J. Morris
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The high viscosity encountered during freezing in glycerol solutions: effects on cryopreservation
G. John Morris
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Martha Goodrich
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Elizabeth Acton
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Caractérisation et lyophilisation de matrices fromagères
Catherine Béal
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Fernanda Fonseca
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A. Thomas
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Michèle Marin
Sciences des aliments = Food science : an international journal of food science and technology, 2006, 26 (1), pp.89-102. ⟨10.3166/sda.26.89-102⟩
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Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage
Stéphanie S. Passot
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M. Alarcon-Lorca
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D. Rolland
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Michèle Marin
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Effect of sucrose and maltodextrin on the physical properties and survival of air-dried Lactobacillus bulgaricus: an in situ fourier transform infrared spectroscopy study
Harriëtte Oldenhof
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Willem F. Wolkers
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Fernanda Fonseca
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Stéphanie S. Passot
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Collapse temperature of bacterial suspensions: the effect of cell type and concentration
Fernanda Fonseca
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Stéphanie S. Passot
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Pascale Lieben
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Michèle Marin
Cryo Letters, 2004, 25 (4), pp.425-434
Journal articles
hal-02672062v1
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Collapse temperature of freeze-dried Lactobacillus bulgaricus suspensions and protective media
Fernanda Fonseca
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Stéphanie S. Passot
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O. Cunin
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Michèle Marin
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Improvement of cryopreservation of Lactobacillus delbrueckii subsp. bulgaricus CFL1 with additives displaying different protective effects
Fernanda Fonseca
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Catherine Béal
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Fatma Mihoub
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Michèle Marin
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Georges G. Corrieu
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Improvement of cryopreservation of Lactobacillus delbruekii subsp bulgaricus CFL1 with additives displaying different protective effects
Fernanda Fonseca
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Catherine Béal
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Fatma Mihoub
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Michèle Marin
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Georges Corrieu
International Dairy Journal, 2003, 13 (11), pp.917-926
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State diagrams and sorption isotherms of bacterial suspensions and fermented medium
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Catherine Béal
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Michèle Marin
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Operating conditions that affect the resistance of lactic acid bacteria to freezing and frozen storage
Fernanda Fonseca
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Catherine Béal
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Georges Corrieu
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Resistance to freezing and frozen storage of Streptococcus thermophilus is related to membrane fatty acid composition
Catherine Béal
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Fernanda Fonseca
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Georges Corrieu
Journal of Dairy Science, 2001, 84 (11), pp.2347-2356
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Resistance to freezing and to frozen storage of Streptococcus themophilus is related to membrane fatty acid composition
Catherine Béal
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Fernanda Fonseca
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Georges G. Corrieu
Journal of Dairy Science, 2001, 84 (11), pp.2347-2356
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Method of quantifying the loss of acidification activity of lactic acid starters during freezing and frozen storage
Fernanda Fonseca
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Catherine Béal
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Georges Corrieu
Journal of Dairy Research, 2000, 67 (1), pp.83-90
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