Fernando REAL

Fernando Real Curriculum vitae
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HIV-1 inhibits IFITM3 expression to promote the infection of megakaryocytes

Cyrine Bentaleb , Souad Adrouche , Jade Finkelstein , Christelle Devisme , Nathalie Callens et al.

Journal of molecular cell biology, 2024, 16 (9), pp.mjae042. ⟨10.1093/jmcb/mjae042⟩

Article dans une revue hal-04764699v1

Protocol to detect infectious SARS-CoV-2 at low levels using in situ hybridization techniques

Andréa Cottignies-Calamarte , Feifan He , Aiwei Zhu , Fernando Real , Morgane Bomsel

STAR Protocols, 2023, 4 (4), pp.102593. ⟨10.1016/j.xpro.2023.102593⟩

Article dans une revue hal-04253093v1

Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment

Jyoti Chauhan , Erika Cecon , Nedjma Labani , Florence Gbahou , Fernando Real et al.

European Journal of Medicinal Chemistry, 2023, 249, pp.115152. ⟨10.1016/j.ejmech.2023.115152⟩

Article dans une revue hal-04090616v1
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Editorial: Platelet and megakaryocyte dysfunctions in infectious diseases

Alice Assinger , Claude Capron , Fernando Real , Morgane Bomsel

Frontiers in Immunology, 2023, 14, ⟨10.3389/fimmu.2023.1175200⟩

Article dans une revue hal-04248788v1
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Protocol to detect infectious SARS-CoV-2 at low levels using in situ hybridization techniques

Andréa Cottignies-Calamarte , Feifan He , Aiwei Zhu , Fernando Real , Morgane Bomsel

STAR Protocols, 2023, 4 (4), pp.102593. ⟨10.1016/j.xpro.2023.102593⟩

Article dans une revue hal-04248785v1

Protocol to detect infectious SARS-CoV-2 at low levels using in situ hybridization techniques

Andréa Cottignies-Calamarte , Feifan He , Aiwei Zhu , Fernando Real , Morgane Bomsel

STAR Protocols, 2023, 4 (4), pp.102593. ⟨10.1016/j.xpro.2023.102593⟩

Article dans une revue hal-04277802v1

Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment

Jyoti Chauhan , Erika Cecon , Nedjma Labani , Florence Gbahou , Fernando Real et al.

European Journal of Medicinal Chemistry, 2023, 249, pp.115152. ⟨10.1016/j.ejmech.2023.115152⟩

Article dans une revue hal-04253097v1

Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment

Jyoti Chauhan , Erika Cecon , Nedjma Labani , Florence Gbahou , Fernando Real et al.

European Journal of Medicinal Chemistry, 2023, 249, pp.115152. ⟨10.1016/j.ejmech.2023.115152⟩

Article dans une revue hal-04266695v1
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HIV-Sheltering Platelets From Immunological Non-Responders Induce a Dysfunctional Glycolytic CD4+ T-Cell Profile

Aiwei Zhu , Fernando Real , Jaja Zhu , Ségolène Greffe , Pierre de Truchis et al.

Frontiers in Immunology, 2022, 12, ⟨10.3389/fimmu.2021.781923⟩

Article dans une revue hal-03604091v1
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S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo

Fernando Real , Aiwei Zhu , Boxin Huang , Ania Belmellat , Alexis Sennepin et al.

Nature Communications, 2022, ⟨10.1038/s41467-022-33401-x⟩

Article dans une revue hal-03808067v1
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Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19

Aiwei Zhu , Fernando Real , Claude C. Capron , Arielle R. Rosenberg , Aymeric Silvin et al.

Cellular and Molecular Life Sciences, 2022, 79 (7), ⟨10.1007/s00018-022-04318-x⟩

Article dans une revue hal-03775756v2
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Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis

Maria Julia Ruiz , Gabriel Siracusano , Andréa Cottignies-Calamarte , Daniela Tudor , Fernando Real et al.

Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.842468⟩

Article dans une revue hal-03796545v1
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S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo

Fernando Real , Aiwei Zhu , Boxin Huang , Ania Belmellat , Alexis Sennepin et al.

Nature Communications, 2022, 13, ⟨10.1038/s41467-022-33401-x⟩

Article dans une revue hal-03810505v1
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Therapeutic potential of melatonin and melatonergic drugs on K18‐hACE2 mice infected with SARS‐CoV‐2

Erika Cecon , Charlotte Izabelle , Sophie Le Poder , Fernando Real , Aiwei Zhu et al.

Journal of Pineal Research, 2022, 72 (1), pp.e12772. ⟨10.1111/jpi.12772⟩

Article dans une revue hal-03800421v1

S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo

Fernando Real , Aiwei Zhu , Boxin Huang , Ania Belmellat , Alexis Sennepin et al.

Nature Communications, 2022, 13 (1), pp.5956. ⟨10.1038/s41467-022-33401-x⟩

Article dans une revue hal-04253106v1
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Un passager clandestin

Fernando Real , Aiwei Zhu , Morgane Bomsel

Médecine/Sciences, 2021, 37 (3), pp.226-230. ⟨10.1051/medsci/2021006⟩

Article dans une revue hal-03175323v1

Isolation of intact Leishmania amazonensis large parasitophorous vacuoles from infected macrophages by density gradient fractionation

Fernando Real

Experimental Parasitology, 2020, 218, pp.107989. ⟨10.1016/j.exppara.2020.107989⟩

Article dans une revue hal-03796869v1
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Isolation of intact Leishmania amazonensis large parasitophorous vacuoles from infected macrophages by density gradient fractionation

Fernando Real

Experimental Parasitology, 2020, 218, pp.107989 -. ⟨10.1016/j.exppara.2020.107989⟩

Article dans une revue hal-03491212v1

Dual Host-Intracellular Parasite Transcriptome of Enucleated Cells Hosting Leishmania amazonensis : Control of Half-Life of Host Cell Transcripts by the Parasite

Cristina Orikaza , Carina Pessoa , Fernanda Paladino , Pilar Florentino , Clara Barbiéri et al.

Infection and Immunity, 2020, 88 (11), ⟨10.1128/IAI.00261-20⟩

Article dans une revue hal-03796638v1
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Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4 + T cell recovery can harbor replication-competent HIV despite viral suppression

Fernando Real , Claude Capron , Alexis Sennepin , Riccardo Arrigucci , Aiwei Zhu et al.

Science Translational Medicine, 2020, 12, pp.eaat6263. ⟨10.1126/scitranslmed.aat626⟩

Article dans une revue hal-03000932v1
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HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy

Yonatan Ganor , Fernando Real , Alexis Sennepin , Charles-Antoine Dutertre , Lisa Prevedel et al.

Nature Microbiology, 2019, 4, pp.633-644. ⟨10.1038/s41564-018-0335-z⟩

Article dans une revue inserm-02019067v1

ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis

Carina Carraro Pessoa , Luiza Campos Reis , Eduardo Milton Ramos-Sanchez , Cristina Mary Orikaza , Cristian Cortez et al.

PLoS Pathogens, 2019, 15 (6), pp.e1007834. ⟨10.1371/journal.ppat.1007834⟩

Article dans une revue hal-03796690v1

Platelets from cART-suppressed HIV-infected patients with poor CD4+T cell 1 recovery carry infectious HIV

Fernando Real , Claude Capron , Alexis Sennepin , Riccardo Arrigucci , Aiwei Zhu et al.

Science Translational Medicine, 2019

Article dans une revue hal-02353509v1
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Visualisation en temps réel de l’infection de la muqueuse génitale par le VIH

Fernando Real , Morgane Bomsel

Médecine/Sciences, 2019, 35 (3), pp.209-212. ⟨10.1051/medsci/2019044⟩

Article dans une revue hal-02355295v1
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Live Imaging of HIV-1 Transfer across T Cell Virological Synapse to Epithelial Cells that Promotes Stromal Macrophage Infection

Fernando Real , Alexis Sennepin , Yonatan Ganor , Alain Schmitt , Morgane Bomsel

Cell Reports, 2018, 23 (6), pp.1794-1805. ⟨10.1016/j.celrep.2018.04.028⟩

Article dans une revue hal-02348307v1

A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes

Pilar Florentino , Fernando Real , Cristina Orikaza , Julia da Cunha , Francisca Vitorino et al.

Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00693⟩

Article dans une revue hal-03796716v1
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The Human Penis Is a Genuine Immunological Effector Site

Alexis Sennepin , Fernando Real , Marine Duvivier , Yonatan Ganor , Sonia Henry et al.

Frontiers in Immunology, 2017, 8, ⟨10.3389/fimmu.2017.01732⟩

Article dans une revue hal-02348410v1

Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis

Karina Luiza Dias-Teixeira , Teresa Calegari-Silva , Jorge Medina , Áislan Vivarini , Átila Cavalcanti et al.

Scientific Reports, 2017, 7 (1), pp.17074. ⟨10.1038/s41598-017-17252-x⟩

Article dans une revue hal-03796737v1

Increased survival and proliferation of the epidemic strain Mycobacterium abscessus subsp. massiliense CRM0019 in alveolar epithelial cells

Giovanni Monteiro Ribeiro , Cristianne Kayoko Matsumoto , Fernando Real , Daniela Teixeira , Rafael Silva Duarte et al.

BMC Microbiology, 2017, 17 (1), pp.195. ⟨10.1186/s12866-017-1102-7⟩

Article dans une revue hal-03796742v1

Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species

Jéssica Cristina dos Santos , Bas Heinhuis , Rodrigo Saar Gomes , Michelle Damen , Fernando Real et al.

PLoS Neglected Tropical Diseases, 2017, 11 (2), pp.e0005413. ⟨10.1371/journal.pntd.0005413⟩

Article dans une revue hal-03796751v1

Lysosome biogenesis/scattering increases host cell susceptibility to invasion by Trypanosoma cruzi metacyclic forms and resistance to tissue culture trypomastigotes

Cristian Cortez , Fernando Real , Nobuko Yoshida

Cellular Microbiology, 2016, 18 (5), pp.748-760. ⟨10.1111/cmi.12548⟩

Article dans une revue hal-03796765v1

Trypanosoma cruzi Differentiates and Multiplies within Chimeric Parasitophorous Vacuoles in Macrophages Coinfected with Leishmania amazonensis

Carina Carraro Pessoa , Éden Ramalho Ferreira , Ethel Bayer-Santos , Michel Rabinovitch , Renato Arruda Mortara et al.

Infection and Immunity, 2016, 84 (5), pp.1603-1614. ⟨10.1128/IAI.01470-15⟩

Article dans une revue hal-03796767v1

AC ‐1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model

Aline Rabaça , Denise Arruda , Carlos Figueiredo , Mariana Massaoka , Camyla Farias et al.

FEBS Open Bio, 2016, 6 (9), pp.885-901. ⟨10.1002/2211-5463.12080⟩

Article dans une revue hal-03796762v1

Cyclopalladated Compound 7a Induces Apoptosis- and Autophagy-Like Mechanisms in Paracoccidioides and Is a Candidate for Paracoccidioidomycosis Treatment

Denise Arruda , Alisson Matsuo , Luiz Silva , Fernando Real , Natanael Leitão et al.

Antimicrobial Agents and Chemotherapy, 2015, 59 (12), pp.7214-7223. ⟨10.1128/AAC.00512-15⟩

Article dans une revue hal-03796774v1

Lysosomal integral membrane protein 2 (LIMP-2) restricts the invasion of Trypanosoma cruzi extracellular amastigotes through the activity of the lysosomal enzyme β-glucocerebrosidase

Viviane Martinelli Gonçalves , Vânia d'Almeida , Karen Barbosa Müller , Fernando Real , Renato Arruda Mortara

Microbes and Infection, 2014, 16 (3), pp.253-260. ⟨10.1016/j.micinf.2013.11.004⟩

Article dans une revue istex hal-03796801v1

Cell‐to‐cell transfer of L eishmania amazonensis amastigotes is mediated by immunomodulatory LAMP ‐rich parasitophorous extrusions

Fernando Real , Pilar Tavares Veras Florentino , Luiza Campos Reis , Eduardo Ramos-Sanchez , Patricia Sampaio Tavares Veras et al.

Cellular Microbiology, 2014, 16 (10), pp.1549-1564. ⟨10.1111/cmi.12311⟩

Article dans une revue hal-03796794v1

An Historical Perspective on How Advances in Microscopic Imaging Contributed to Understanding the Leishmania Spp. and Trypanosoma cruzi Host-Parasite Relationship

P. Florentino , F. Real , A. Bonfim-Melo , C. Orikaza , E. Ferreira et al.

BioMed Research International , 2014, 2014, pp.1-16. ⟨10.1155/2014/565291⟩

Article dans une revue hal-03796796v1

The Genome Sequence of Leishmania (Leishmania) amazonensis: Functional Annotation and Extended Analysis of Gene Models

F. Real , R. Vidal , M. Carazzolle , J. Mondego , G. Costa et al.

DNA Research, 2013, 20 (6), pp.567-581. ⟨10.1093/dnares/dst031⟩

Article dans une revue hal-03796806v1

The Diverse and Dynamic Nature of Leishmania Parasitophorous Vacuoles Studied by Multidimensional Imaging

Fernando Real , Renato Mortara

PLoS Neglected Tropical Diseases, 2012, 6 (2), pp.e1518. ⟨10.1371/journal.pntd.0001518⟩

Article dans une revue hal-03796811v1

Fusion between Leishmania amazonensis and Leishmania major Parasitophorous Vacuoles: Live Imaging of Coinfected Macrophages

Fernando Real , Renato Mortara , Michel Rabinovitch

PLoS Neglected Tropical Diseases, 2010, 4 (12), pp.e905. ⟨10.1371/journal.pntd.0000905⟩

Article dans une revue hal-03796817v1

Leishmania (L.) amazonensis: Fusion between parasitophorous vacuoles in infected bone-marrow derived mouse macrophages

F. Real , M. Pouchelet , M. Rabinovitch

Experimental Parasitology, 2008, 119 (1), pp.15-23. ⟨10.1016/j.exppara.2007.12.013⟩

Article dans une revue istex hal-03796820v1

Apoptotic mimicry: an altruistic behavior in host/Leishmania interplay

J.L.M. Wanderley , A. Benjamin , F. Real , A. Bonomo , M.E.C. Moreira et al.

Brazilian Journal of Medical and Biological Research, 2005, 38 (6), pp.807-812. ⟨10.1590/S0100-879X2005000600001⟩

Article dans une revue hal-03796823v1