Francesca Di Nunzio

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Publications

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Tracking HIV-1 DNA fate from cell culture to humanized mice tissues

Jean-Sebastien Diana , Evgeny Tatirovsky , Chiara Tomasini , Céline Cuche , Selen Ay et al.

Molecular Therapy Advances, 2026, 34 (1), pp.201690. ⟨10.1016/j.omta.2026.201690⟩

Article dans une revue pasteur-05527218v1
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Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle

Chiara Tomasini , Céline Cuche , Selen Ay , Maxence Collard , Bin Cui et al.

eLife, 2026, 13, ⟨10.7554/eLife.103725⟩

Article dans une revue pasteur-05117096v3
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La capside du VIH-1

Thierry Mourer , Francesca Di Nunzio

Médecine/Sciences, 2025, 41 (3), pp.219-222. ⟨10.1051/medsci/2025028⟩

Article dans une revue hal-05001671v1
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In vivo HIV-1 nuclear condensates safeguard against cGAS and license reverse transcription

Selen Ay , Julien Burlaud-Gaillard , Anastasia Gazi , Yevgeniy Tatirovsky , Céline Cuche et al.

EMBO Journal, 2024, ⟨10.1038/s44318-024-00316-w⟩

Article dans une revue pasteur-04826770v1
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HIV-Induced CPSF6 Condensates

Selen Ay , Francesca Di Nunzio

Journal of Molecular Biology, 2023, pp.168094. ⟨10.1016/j.jmb.2023.168094⟩

Article dans une revue pasteur-04126694v1
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HIV-induced membraneless organelles orchestrate post-nuclear entry steps

Viviana Scoca , Renaud Morin , Maxence Collard , Jean-Yves Tinevez , Francesca Di Nunzio

Journal of molecular cell biology, 2023, 14 (11), pp.mjac060. ⟨10.1093/jmcb/mjac060⟩

Article dans une revue hal-04264224v3
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Biomolecular condensates: insights into early and late steps of the HIV-1 replication cycle.

Francesca Di Nunzio , Vladimir Uversky , Andrew Mouland

Retrovirology, 2023, 20 (1), pp.4. ⟨10.1186/s12977-023-00619-6⟩

Article dans une revue pasteur-04126418v1

Stress-induced condensate switch awakens sleeping viruses

Francesca Di Nunzio

Cell Host & Microbe, 2023, 31 (5), pp.679-680. ⟨10.1016/j.chom.2023.04.008⟩

Article dans une revue pasteur-04126658v1
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The Viral Capsid: A Master Key to Access the Host Nucleus

Guillermo Blanco-Rodriguez , Francesca Di Nunzio

Viruses, 2021, 13 (6), pp.1178. ⟨10.3390/v13061178⟩

Article dans une revue pasteur-03344209v1
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Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2

Viviana Scoca , Francesca Di Nunzio

Journal of molecular cell biology, 2021, ⟨10.1093/jmcb/mjab020⟩

Article dans une revue pasteur-03214326v1

The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion

Viviana Scoca , Francesca Di Nunzio

Viruses, 2021, 13 (2), pp.273. ⟨10.3390/v13020273⟩

Article dans une revue pasteur-03214327v1
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Clustering and reverse transcription of HIV‐1 genomes in nuclear niches of macrophages

Elena Rensen , Florian Mueller , Viviana Scoca , Jyotsana Parmar , Philippe Souque et al.

EMBO Journal, 2021, 40 (1), pp.e105247. ⟨10.15252/embj.2020105247⟩

Article dans une revue pasteur-03088393v1
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Remodeling of the core leads HIV-1 pre-integration complex in the nucleus of human lymphocytes.

Guillermo Blanco-Rodriguez , Anastasia Gazi , Blandine Monel , Stella Frabetti , Viviana Scoca et al.

Journal of Virology, 2020, [Epub ahead of print], pp.JVI.00135-20. ⟨10.1128/JVI.00135-20⟩

Article dans une revue pasteur-02548457v1
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Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core

Anastasia Selyutina , Mirjana Persaud , Lacy Simons , Angel Bulnes-Ramos , Cindy Buffone et al.

Cell Reports, 2020, 30 (11), pp.3766-3777.e6. ⟨10.1016/j.celrep.2020.02.100⟩

Article dans une revue pasteur-03106108v1
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Les facteurs du pore nucléaire : un collectif gagnant pour la translocation et l’intégration du VIH-1

François Berry , Pierre Khalfi , Florra Maillot , Paul Seigneres , Samy Sid Ahmed et al.

Médecine/Sciences, 2018, 34 (6-7), pp.512-515. ⟨10.1051/medsci/20183406006⟩

Article dans une revue hal-02970124v1

Genetic Flexibility of the NKNK Motif in HIV-1 Integrases Allows Its Involvement in Multiple Functions During Infection

Marine Kanja , Pierre Cappy , Guillermo Blanco-Rodriguez , Nicolas Levy , Sylvie Schmidt et al.

Synthetic Biology eJournal, 2018, ⟨10.2139/ssrn.3208264⟩

Article dans une revue hal-03008742v1

Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells

Cindy Buffone , Alicia Martinez-Lopez , Thomas Fricke , Silvana Opp , Marco Severgnini et al.

Journal of Virology, 2018, 92 (19), pp.e00648-18. ⟨10.1128/JVI.00648-18⟩

Article dans une revue pasteur-03106145v1

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV

Daniel A. Donahue , Sonia Amraoui , Francesca Di Nunzio , Camille Kieffer , Françoise Porrot et al.

Journal of Virology, 2016, 90 (8), pp.4199 - 4214. ⟨10.1128/JVI.03202-15⟩

Article dans une revue pasteur-01372386v1

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

Bianca Schulte , Cindy Buffone , Silvana Opp , Francesca Di Nunzio , Daniel Augusto de Souza Aranha Vieira et al.

Journal of Virology, 2015, 89 (16), pp.8599 - 8610. ⟨10.1128/JVI.00753-15⟩

Article dans une revue pasteur-01536195v1
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Chromatin organization at the nuclear pore favours HIV replication.

Mickaël Lelek , Nicoletta Casartelli , Danilo Pellin , Ermanno Rizzi , Philippe Souque et al.

Nature Communications, 2015, 6, pp.6483. ⟨10.1038/ncomms7483⟩

Article dans une revue pasteur-01536149v1
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Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.

Hao Wang , Ming-Chieh Shun , Xiang Li , Francesca Di Nunzio , Stephen Hare et al.

Molecular Therapy - Methods and Clinical Development, 2014, 1 (2), ⟨10.1038/mtm.2013.2⟩

Article dans une revue hal-01536152v1

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

Francesca Di Nunzio

Virus Research, 2013, 178 (2), pp.187-96. ⟨10.1016/j.virusres.2013.09.003⟩

Article dans une revue pasteur-01536158v1

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

Francesca Di Nunzio , Thomas Fricke , Annarita Miccio , Jose Carlos Valle-Casuso , Patricio Perez et al.

Virology, 2013, 440 (1), pp.8-18. ⟨10.1016/j.virol.2013.02.008⟩

Article dans une revue pasteur-01536160v1
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TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication

Mehdi Morchikh , Monica Naughtin , Francesca Di Nunzio , Johan Xavier , Pierre Charneau et al.

PLoS ONE, 2013, 8, pp.81217 - 81217. ⟨10.1371/journal.pone.0081217.s005⟩

Article dans une revue pasteur-01416848v1

Superresolution imaging of HIV in infected cells with FlAsH-PALM.

Mickaël Lelek , Francesca Di Nunzio , Ricardo Henriques , Pierre Charneau , Nathalie Arhel et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (22), pp.8564-9. ⟨10.1073/pnas.1013267109⟩

Article dans une revue pasteur-01536166v1
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TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core.

Jose Carlos Valle-Casuso , Francesca Di Nunzio , Yang Yang , Natalia Reszka , Maritza Lienlaf et al.

Journal of Virology, 2012, 86 (10), pp.5931-6. ⟨10.1128/JVI.00451-12⟩

Article dans une revue hal-00762028v1

HIV-derived vectors for therapy and vaccination against HIV

Francesca Di Nunzio , T. Félix , N.J. Arhel , S. Nisole , P. Charneau et al.

Vaccine, 2012, 30 (15), pp.2499-2509. ⟨10.1016/j.vaccine.2012.01.089⟩

Article dans une revue istex hal-02142314v1
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Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

Francesca Di Nunzio , Anne Danckaert , Thomas Fricke , Patricio Perez , Juliette Fernandez et al.

PLoS ONE, 2012, 7 (9), pp.e46037. ⟨10.1371/journal.pone.0046037⟩

Article dans une revue pasteur-01536163v1

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.

Maritza Lienlaf , Fumiaki Hayashi , Francesca Di Nunzio , Naoya Tochio , Takanori Kigawa et al.

Journal of Virology, 2011, 85 (17), pp.8725-37. ⟨10.1128/JVI.00497-11⟩

Article dans une revue pasteur-01536176v1
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Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

Candela Iglesias , Mathieu Ringeard , Francesca Di Nunzio , Juliette Fernandez , Raphael Gaudin et al.

Retrovirology, 2011, 8 (1), pp.92. ⟨10.1186/1742-4690-8-92⟩

Article dans une revue pasteur-00646599v1
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Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.

Mohd J Dar , Blandine Monel , Lavanya Krishnan , Ming-Chieh Shun , Francesca Di Nunzio et al.

Retrovirology, 2009, 6 (1), pp.94. ⟨10.1186/1742-4690-6-94⟩

Article dans une revue pasteur-01536178v1
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Structural basis for functional tetramerization of lentiviral integrase.

Stephen Hare , Francesca Di Nunzio , Alfred Labeja , Jimin Wang , Alan Engelman et al.

PLoS Pathogens, 2009, 5 (7), pp.e1000515. ⟨10.1371/journal.ppat.1000515⟩

Article dans une revue pasteur-01536181v1

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.

Ming-Chieh Shun , Yaïr Botbol , Xiang Li , Francesca Di Nunzio , Janet E Daigle et al.

Journal of Virology, 2008, 82 (23), pp.11555-67. ⟨10.1128/JVI.01561-08⟩

Article dans une revue pasteur-01536189v1
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Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors.

Francesca Di Nunzio , Giulietta Maruggi , Stefano Ferrari , Enzo Di Iorio , Valentina Poletti et al.

Molecular Therapy, 2008, 16 (12), pp.1977-85. ⟨10.1038/mt.2008.204⟩

Article dans une revue hal-01536184v1

Transduction of Human Hematopoietic Stem Cells by Lentiviral Vectors Pseudotyped with the RD114-TR Chimeric Envelope Glycoprotein

Francesca Di Nunzio , B. Piovani , Cosset François-Loïc , F. Mavilio , A. Stornaiuolo

Human Gene Therapy, 2007, 18 (9), pp.811-820. ⟨10.1089/hum.2006.138⟩

Article dans une revue hal-03110979v1

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

Fulvio Mavilio , Graziella Pellegrini , Stefano Ferrari , Francesca Di Nunzio , Enzo Di Iorio et al.

Nature Medicine, 2006, 12 (12), pp.1397-402. ⟨10.1038/nm1504⟩

Article dans une revue pasteur-01536191v1

Characterization of Nuclear HIV-Induced Membraneless Organelles Through Fluorescence Microscopy

Viviana Scoca , Francesca Di Nunzio

Vinayaka R. Prasad; Ganjam V. Kalpana. HIV Protocols [4th edition], 2807, Springer, pp.113-125, 2024, Methods in Molecular Biology, 978-1-0716-3861-3. ⟨10.1007/978-1-0716-3862-0_8⟩

Chapitre d'ouvrage pasteur-04598269v1

Nuclear Pore Complexes, Genome Organization and HIV-1 Infection

Francesca Di Nunzio

Nuclear Pore Complexes in Genome Organization, Function and Maintenance, Springer International Publishing, pp.183-199, 2018, 978-3-319-71614-5. ⟨10.1007/978-3-319-71614-5_8⟩

Chapitre d'ouvrage hal-03110980v1

FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling.

Mickaël Lelek , Francesca Di Nunzio , Christophe Zimmer

Andrei I. Ivanov. Exocytosis and Endocytosis, 1174, Springer New York, pp.183-93, 2014, Methods in Molecular Biology, 978-1-4939-0943-8. ⟨10.1007/978-1-4939-0944-5_12⟩

Chapitre d'ouvrage pasteur-01536156v1