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Franck Morel

Professeur des Universités Université de Poitiers
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Publications

Liposomal co-encapsulation of a novel gemini lipopeptide and a CpG-ODN induces a strong Th1 response with the co-activation of a Th2/Th17 profile and high antibody levels

Ivana Gabriela Reidel , Cecilia Carol Curti , Léa Dorémus , Emile Béré , Adriana Delwail
Journal articles hal-04490420v1
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Interleukin 34 exerts anti-inflammatory activities on keratinocytes and is down-regulated in psoriatic-inflamed skin

Magali Croquette , Alicia Faugeroux , Clémence Fonlupt , Julie Godet , Éric Frouin
Journal of Investigative Dermatology, 2023, ⟨10.1016/j.jid.2023.05.023⟩
Journal articles hal-04133828v1

Salivary metabolome indicates a shift in tyrosine metabolism in patients with burning mouth syndrome: a prospective case–control study

Charlotte Moreau , Chakib El Habnouni , Jean-Claude Lecron , Franck Morel , Adriana Delwail
Pain, 2023, 164 (3), pp.e144-e156. ⟨10.1097/j.pain.0000000000002733⟩
Journal articles hal-03886871v1

The M2 macrophages infiltration of sebaceous tumors is linked to the aggressiveness of tumors but not to the mismatch repair pathway

Eric Frouin , Camille Alleyrat , Julie Godet , Lucie Karayan-Tapon , Hélinie Sinson
Journal of Cancer Research and Clinical Oncology, 2023, 149 (9), pp.6445-6454. ⟨10.1007/s00432-023-04629-x⟩
Journal articles hal-04185363v1
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IL-22 Promotes Neural Stem Cell Self-Renewal in the Adult Brain

Valérie Coronas , Patricia Arnault , Jean-François Jégou , Laetitia Cousin , Hanitriniaina Rabeony
STEM CELLS, 2023, 41 (3), pp.252-259. ⟨10.1093/stmcls/sxad003⟩
Journal articles hal-04003042v1
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Ex vivo cytokine production in psoriatic disease: Towards specific signatures in cutaneous psoriasis and peripheral psoriatic arthritis

Guillaume Larid , Adriana Delwail , Thomas Dalle , Philippe Vasseur , Christine Silvain
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.993363⟩
Journal articles hal-03894861v1
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Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes

Sevda Cordier-Dirikoc , Nathalie Pedretti , Julien Garnier , Sandrine Clarhaut-Charreau , Bernhard Ryffel
Frontiers in Immunology, 2022, 13, pp.984045. ⟨10.3389/fimmu.2022.984045⟩
Journal articles hal-03801039v1
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IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin

Jean-Claude Lecron , Sandrine Clarhaut-Charreau , Laure Favot-Laforge , Jean-François Jégou , Charles Bodet
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.984016⟩
Journal articles hal-04185385v1
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A Marine λ-Oligocarrageenan Inhibits Migratory and Invasive Ability of MDA-MB-231 Human Breast Cancer Cells through Actions on Heparanase Metabolism and MMP-14/MMP-2 Axis

Rémi Cousin , Hugo Groult , Chanez Manseur , Romain Ferru-Clément , Mario Gani
Marine drugs, 2021, 19 (10), pp.546. ⟨10.3390/md19100546⟩
Journal articles hal-03369118v1
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Chronic Alcohol Consumption Exacerbates the Severity of Psoriasiform Dermatitis in Mice

Philippe Vasseur , Mathilde Pohin , Coralie Gisclard , Jean‐François Jégou , Franck Morel
Alcoholism: Clinical and Experimental Research, 2020, 44 (9), pp.1728-1733. ⟨10.1111/acer.14400⟩
Journal articles hal-03797226v1

Photometric computer vision-aided system for psoriasis severity scoring: a preclinical study based on a mouse model of psoriasis

Taoufik El Kabir , Benjamin Bringier , Majdi Khoudeir , Franck Morel , Jean-Claude Lecron
Journal of Electronic Imaging, 2020, 29 (04), pp.1. ⟨10.1117/1.JEI.29.4.041003⟩
Journal articles hal-02516809v1

Cytokine Signature in Schnitzler Syndrome: Proinflammatory Cytokine Production Associated to Th Suppression

Marie Masson Regnault , Eric Frouin , Isabelle Jéru , Adriana Delwail , Sandrine Charreau
Frontiers in Immunology, 2020, 11, pp.1-8. ⟨10.3389/fimmu.2020.588322⟩
Journal articles hal-03574422v1

Skin inflammatory response and efficacy of anti-epidermal growth factor receptor therapy in metastatic colorectal cancer (CUTACETUX)

David Tougeron , Sheik Emambux , Laure Favot , Thierry Lecomte , Ewa Wierzbicka-Hainaut
OncoImmunology, 2020, 9 (1), pp.1848058. ⟨10.1080/2162402X.2020.1848058⟩
Journal articles hal-03149030v1
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Type-1 cytokines regulate MMP-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo.

Nesrine Boukhedouni , Christina Martins , Anne-Sophie Darrigade , Claire Drullion , Jérôme Rambert
JCI Insight, 2020, 5 (11), pp.e133772. ⟨10.1172/jci.insight.133772⟩
Journal articles hal-03436855v1
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Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers

Vincent Huguier , Jean-Philippe Giot , Marie Simonneau , Pierre Levillain , Sandrine Charreau
Scientific Reports, 2019, 9 (1), pp.2113. ⟨10.1038/s41598-019-38572-0⟩
Journal articles hal-04184816v1
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Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression

Marie Simonneau , Eric Frouin , Vincent Huguier , Cynthia Jermidi , Jean François Jégou
Oncotarget, 2018, 9 (92), pp.36457-36473. ⟨10.18632/oncotarget.26355⟩
Journal articles hal-04186396v1
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Liver fibrosis is associated with cutaneous inflammation in the imiquimod-induced murine model of psoriasiform dermatitis

P. Vasseur , M. Pohin , Jf. Jégou , L. Favot , N. Venisse
British Journal of Dermatology, 2018, 179, pp.101-109. ⟨10.1111/bjd.16137⟩
Journal articles hal-01699551v1
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Development of a new model of reconstituted mouse epidermis and characterization of its response to proinflammatory cytokines

Mathilde Pohin , Carolina Veaute , Julien Garnier , Christine Barrault , Laure Cronier
Journal of Tissue Engineering and Regenerative Medicine, 2018, 12, pp.e1098- e1107. ⟨10.1002/term.2442⟩
Journal articles hal-01699562v1

Th-17 response and antimicrobial peptide expression are uniformly expressed in gastric mucosa of Helicobacter pylori -infected patients independently of their clinical outcomes

Julie Cremniter , Charles Bodet , David Tougeron , Xavier Dray , Joëlle Guilhot
Helicobacter, 2018, 23, pp.e12479. ⟨10.1111/hel.12479⟩
Journal articles hal-01780541v1
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Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis

Elodie Couderc , Franck Morel , Pierre Levillain , Amandine Buffière-Morgado , Magalie Camus
PLoS ONE, 2017, 12 (7), pp.e0181486. ⟨10.1371/journal.pone.0181486⟩
Journal articles hal-01703911v1

Characterization of skin Th17 transcriptional profiles in psoriatic patients under adalimumab biotherapy

Amandine Buffière-Morgado , Elodie Couderc , Adriana Delwail , Laure Favot , Jean-François Jégou
European Journal of Dermatology, 2017, ⟨10.1684/ejd.2017.3127⟩
Journal articles hal-01705097v1

High-Fat Diet-Induced IL-17A Exacerbates Psoriasiform Dermatitis in a Mouse Model of Steatohepatitis

Philippe Vasseur , Laura Serres , Jean-Francois Jegou , Mathilde Pohin , Adriana Delwail
American Journal of Pathology, 2016, 186 (9), pp.2292--2301. ⟨10.1016/j.ajpath.2016.05.012⟩
Journal articles hal-01390977v1
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Distinct expression of interleukin (IL)-36 α, β and γ , their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease

M.-A. Boutet , G. Bart , M. Penhoat , Jérôme Amiaud , B. Brulin
Clinical and Experimental Immunology, 2016, 184 (2), pp.159-173. ⟨10.1111/cei.12761⟩
Journal articles hal-03153612v1
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Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation

Mathilde Pohin , William Guesdon , Andela Andrine Mekouo , Hanitriniaina Rabeony , Isabelle Petit-Paris
European Journal of Immunology, 2016, 46 (7), pp.1737 - 1751. ⟨10.1002/eji.201546216⟩
Journal articles inserm-01701320v1

IL-17A EXACERBATES PSORIASIFORM DERMATITIS IN A MOUSE MODEL OF HIGH-FAT DIET-INDUCED STEATOHEPATITIS

J.-C. Lecron , P. Vasseur , L. Serres , J.-F. Jégou , M. Pohin
Cytokine, 2016, 87, pp.51--51. ⟨10.1016/j.cyto.2016.07.020⟩
Journal articles hal-01485264v1

Foreskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts

Jiad Mcheik , Christine Barrault , Nathalie Pedretti , Julien Garnier , Franck Juchaux
Journal of Tissue Engineering and Regenerative Medicine, 2016, 10 (3), pp.252 - 260. ⟨10.1002/term.1690⟩
Journal articles hal-01702871v1
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IL22/IL-22R Pathway Induces Cell Survival in Human Glioblastoma Cells

Hussein Akil , Amazigh Abbaci , Barbara Bessette , Lea Costes , Linda Domballe
PLoS ONE, 2015, 10 (3), pp.e0119872. ⟨10.1371/journal.pone.0119872⟩
Journal articles hal-01704496v1

IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome

Hanitriniaina Rabeony , Mathilde Pohin , Philippe Vasseur , Isabelle Petit-Paris , Jean-François Jégou
European Journal of Immunology, 2015, 45 (10), pp.2847 - 2857. ⟨10.1002/eji.201445215⟩
Journal articles hal-01702889v1

Evidence for a subventricular zone neural stem cell phagocytic activity stimulated by the vitamin K-dependent factor protein S.

Aurélie Ginisty , Aurore Gély-Pernot , Loubna Abaamrane , Franck Morel , Patricia Arnault
STEM CELLS, 2015, 33 (2), pp.515-25. ⟨10.1002/stem.1862⟩
Journal articles hal-01206300v1

Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children

Jiad N Mcheik , Christine Barrault , Nathalie Pedretti , Julien Garnier , Franck Juchaux
Burns, 2015, 41 (2), pp.352 - 358. ⟨10.1016/j.burns.2014.07.003⟩
Journal articles hal-01705155v1
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Inhibition of Keratinocyte Differentiation by the Synergistic Effect of IL-17A, IL-22, IL-1α, TNFα and Oncostatin M

Hanitriniaina Rabeony , Isabelle Petit-Paris , Julien Garnier , Christine Barrault , Nathalie Pedretti
PLoS ONE, 2014, 9 (7), ⟨10.1371/journal.pone.0101937⟩
Journal articles hal-01703025v1
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Chemokines and Antimicrobial Peptides Have a cag -Dependent Early Response to Helicobacter pylori Infection in Primary Human Gastric Epithelial Cells

Pascale Mustapha , Isabelle Petit-Paris , Magali Garcia , Cong Tri Tran , Julie Cremniter
Infection and Immunity, 2014, 82 (7), pp.2881 - 2889. ⟨10.1128/IAI.01517-13⟩
Journal articles hal-01699819v1

Involvement of IL-1 and Oncostatin M in Acanthosis Associated With Hypertensive Leg Ulcer

Jean-Philippe Giot , Isabelle Petit-Paris , Pierre Levillain , Vincent Huguier , Sandrine Charreau
American Journal of Pathology, 2013, 182 (3), pp.806 - 818. ⟨10.1016/j.ajpath.2012.11.030⟩
Journal articles hal-01703039v1

Keratinocytes under Fire of Proinflammatory Cytokines: Bona Fide Innate Immune Cells Involved in the Physiopathology of Chronic Atopic Dermatitis and Psoriasis

François-Xavier Bernard , Franck Morel , Magalie Camus , Nathalie Pedretti , Christine Barrault
Asian Pacific journal of allergy and immunology, 2012, 2012, pp.1 - 10. ⟨10.1155/2012/718725⟩
Journal articles hal-01703041v1

Cellular response of the amoeba Acanthamoeba castellanii to chlorine, chlorine dioxide, and monochloramine treatments.

Emerancienne Mogoa , Charles Bodet , Franck Morel , Marie-Hélène Rodier , Bernard Legube
Applied and Environmental Microbiology, 2011, 77 (14), pp.4974-80. ⟨10.1128/AEM.00234-11⟩
Journal articles hal-00715851v1

The Immune Cellular Effectors of Terrestrial Isopod Armadillidium vulgare: Meeting with Their Invaders, Wolbachia

F. Chevalier , J. Herbiniere-Gaboreau , J. Bertaux , M. Raimond , F. Morel
PLoS ONE, 2011, 6 (4), pp.e18531. ⟨10.1371/journal.pone.0018531⟩
Journal articles hal-00591758v1

Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1 , and TNF- Recapitulates Some Features of Psoriasis

Karline Guilloteau , Isabelle Petit-Paris , Nathalie Pedretti , Katia Boniface , Franck Juchaux
Journal of Immunology, 2010, 184 (9), pp.5263 - 5270. ⟨10.4049/jimmunol.0902464⟩
Journal articles hal-01704550v1

45,X/46,XX mosaicism below 30% of aneuploidy: clinical implications in adult women from a reproductive medicine unit.

Lionel Homer , Marie-Thérèse Le Martelot , F. Morel , V. Amice , Véronique Kerlan
European Journal of Endocrinology, 2010, 162 (3), pp.617-23. ⟨10.1530/EJE-09-0750⟩
Journal articles hal-00929846v1

Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes.

Benoit Massonnet , Sylvain Normand , Reinhard Moschitz , Adriana Delwail , Laure Favot
European citokine Network, 2009, 20 (3), pp.112-120. ⟨10.1684/ecn.2009.0162⟩
Journal articles hal-00466975v1

Inhibition of PI3K synergistically enhances the apoptotic effect of STI-571 on p210bcr-abl-transformed cells in a Rac1-dependent manner

Agnès Rioux-Bilan , Thomas Daubon , Franck Morel , Alain Kitzis , Nicolas Bourmeyster
Leukemia Research, 2008, 32 (3), pp.517-519. ⟨10.1016/j.leukres.2007.07.018⟩
Journal articles hal-04034868v1

Reestablishment of damaged adult motor pathways by grafted embryonic cortical neurons

Afsaneh Gaillard , Laetitia Prestoz , Brigitte Dumartin , Anne Cantereau , Franck Morel
Nature Neuroscience, 2007, 10 (10), pp.1294-1299. ⟨10.1038/nn1970⟩
Journal articles hal-00404151v1

Oncostatin M Secreted by Skin Infiltrating T Lymphocytes Is a Potent Keratinocyte Activator Involved in Skin Inflammation

Katia Boniface , Caroline Diveu , Franck Morel , Nathalie Pedretti , Josy Froger
Journal of Immunology, 2007, 178 (7), pp.4615 - 4622. ⟨10.4049/jimmunol.178.7.4615⟩
Journal articles hal-01705182v1

A role for T cell-derived interleukin 22 in psoriatic skin inflammation

Katia Boniface , Emmanuel Guignouard , Nathalie Pedretti , Martine Garcia , F.X. Bernard
Clinical and Experimental Immunology, 2007, 150 (3), pp.407 - 415. ⟨10.1111/j.1365-2249.2007.03511.x⟩
Journal articles hal-01705160v1

IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes

Katia Boniface , F.X. Bernard , Martine Garcia , Austin Gurney , Jean-Claude Lecron
Journal of Immunology, 2005, 174 (6), pp.3695 - 3702. ⟨10.4049/jimmunol.174.6.3695⟩
Journal articles hal-01705207v1

Human cardiomyocyte hypertrophy induced in vitro by gp130 stimulation

Cécile Ancey , Emmanuelle Menet , Pierre Corbi , Sandra Fredj , Martine Garcia-Tamisier
Cardiovascular Research, 2003, 59 (1), pp.78-85. ⟨10.1016/s0008-6363(03)00346-8⟩
Journal articles hal-04483718v1

IL-22, in contrast to IL-10, does not induce Ig production, due to absence of a functional IL-22 receptor on activated human B cells

S. Lecart , F. Morel , N. Noraz , J. Pene , M. Garcia
International Immunology, 2002, 14 (11), pp.1351--1356
Journal articles hal-02197532v1
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Serum soluble CD23 levels in giant cell arteritis'

Pascal Roblot , Franck Morel , Eric Lelièvre , Marie-Hélène Biais-Sauvètre , Donat de Groote
Immunology Letters, 1996, 53 (1), pp.41. ⟨10.1016/0165-2478(96)02612-0⟩
Journal articles inserm-03549093v1

Non invasive control and scoring of psoriasis severity

Taoufik El Kabir , Benjamin Bringier , Majdi Khoudeir , Jean Claude Lecron , Franck Morel
Fifteenth International Conference on Quality Control by Artificial Vision, May 2019, Mulhouse, France. pp.14, ⟨10.1117/12.2520690⟩
Conference papers hal-02374311v1

Diagnostic du psoriasis par vision par ordinateur

Taoufik El Kabir , Benjamin Bringier , Majdi Khoudeir , Jean-François Jégou , Jean Claude Lecron
Symposium en Recherche sur l’inflammation et la Cancérologie Dermatologiques en Nouvelle Aquitaine, Nov 2018, Poitiers, France
Conference papers hal-02374370v1

Diagnostic du psoriasis par la stéréo photométrie

Taoufik El Kabir , Benjamin Bringier , Majdi Khoudeir , Jean François Jegou , Jean Claude Lecron
Journées Imagerie Optique Non-Conventionnelle 2018, Mar 2018, Paris, France
Conference papers hal-02374383v1