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Synthesis of acyclic analogues of adenosine sulfonamides and their activity against RNA cap guanine N 7-methyltransferase of SARS-CoV-2
Rostom Ahmed‐belkacem
,
Adrien Delpal
,
Bruno Canard
,
Jean-Jacques Vasseur
,
Etienne Decroly
et al.
Article dans une revue
hal-04741812
v1
|
|
5′-cap RNA/SAM mimetic conjugates as bisubstrate inhibitors of viral RNA cap 2′-O-methyltransferases
Rostom Ahmed‐belkacem
,
Priscila Sutto-Ortiz
,
Adrien Delpal
,
Joris Troussier
,
Bruno Canard
et al.
Article dans une revue
hal-04456996
v1
|
|
Accelerated, high-quality photolithographic synthesis of RNA microarrays in situ
Tadija Kekić
,
Nemanja Milisavljević
,
Joris Troussier
,
Amina Tahir
,
Françoise Debart
et al.
Article dans une revue
hal-04741717
v1
|
|
N-arylsulfonamide-based adenosine analogues to target RNA cap N7-methyltransferase nsp14 of SARS-CoV-2
Rostom Ahmed‐belkacem
,
Joris Troussier
,
Adrien Delpal
,
Bruno Canard
,
Jean-Jacques Vasseur
et al.
Article dans une revue
hal-04426066
v1
|
|
Serendipitous Synthesis of 5-Hydroxyuridine from 2',3'-O-isopropylidene N4-Acetylcytidine by Hypervalent Iodine(III)-Mediated Reaction
Mary Anne Maverick
,
Mathieu Noël
,
Jean-Jacques Vasseur
,
Carine Baraguey
,
Françoise Debart
et al.
Article dans une revue
hal-04235363
v1
|
|
Access to High‐Purity 7m G‐cap RNA in Substantial Quantities by a Convenient All‐Chemical Solid‐Phase Method
Mathieu Noël
,
Theo Guez
,
Yann Thillier
,
Jean‐jacques Vasseur
,
Françoise Debart
Article dans une revue
hal-04235335
v1
|
|
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5
Mikael Feracci
,
Cécilia Eydoux
,
Véronique Fattorini
,
Lea Lo Bello
,
Pierre Gauffre
et al.
Article dans une revue
hal-04159074
v1
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Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases
Marcel Hausdorff
,
Adrien Delpal
,
Sarah Barelier
,
Laura Nicollet
,
Bruno Canard
et al.
Article dans une revue
hal-04095336
v1
|
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Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect
Priscila El Kazzi
,
Nadia Rabah
,
Célia Chamontin
,
Lina Poulain
,
François Ferron
et al.
Article dans une revue
hal-03860650
v1
|
|
Bisubstrate Strategies to Target Methyltransferases
Rostom Ahmed‐belkacem
,
Françoise Debart
,
Jean‐jacques Vasseur
Article dans une revue
hal-03727961
v1
|
|
Direct Access to Unique C‐5’‐Acyl Modified Nucleosides through Liebeskind–Srogl Cross‐Coupling Reaction
Mary Anne Maverick
,
Marie Gaillard
,
Jean Jacques Vasseur
,
Françoise Debart
,
Michael Smietana
Article dans une revue
hal-03737774
v1
|
|
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome
Ashleigh Shannon
,
Bhawna Sama
,
Pierre Gauffre
,
Théo Guez
,
Françoise Debart
et al.
Article dans une revue
hal-03937366
v1
|
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Facile access to 4′-( N -acylsulfonamide) modified nucleosides and evaluation of their inhibitory activity against SARS-CoV-2 RNA cap N 7-guanine-methyltransferase nsp14
Romain Amador
,
Adrien Delpal
,
Bruno Canard
,
Jean-Jacques Vasseur
,
Etienne Decroly
et al.
Article dans une revue
hal-03801035
v1
|
|
Inhibiteurs bisubstrats de méthyltransférases virales
Rostom Ahmed‐belkacem
,
J.J. Vasseur
,
Francoise Debart
L'Actualité Chimique, 2022
Article dans une revue
hal-03721682
v1
|
|
Importance of RNA length for in vitro encapsidation by the nucleoprotein of human respiratory syncytial virus
Lorène Gonnin
,
Charles-Adrien Richard
,
Irina Gutsche
,
Didier Chevret
,
Joris Troussier
et al.
Article dans une revue
hal-03797501
v2
|
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Potent Inhibition of SARS-CoV-2 nsp14 N 7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues
Rostom Ahmed‐belkacem
,
Marcel Hausdorff
,
Adrien Delpal
,
Priscila Sutto-Ortiz
,
Agathe M G Colmant
et al.
Article dans une revue
hal-03721688
v1
|
|
The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2’-O-methylation
Priscila Sutto-Ortiz
,
Sergey Tcherniuk
,
Nina Ysebaert
,
Pravien Abeywickrema
,
Mathieu Noël
et al.
Article dans une revue
hal-03282037
v1
|
|
FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell
Sébastien Relier
,
Julie Ripoll
,
Hélène Guillorit
,
Amandine Amalric
,
Cyrinne Achour
et al.
Article dans une revue
hal-03178788
v2
|
|
First insights into the structural features of Ebola virus methyltransferase activities
Coralie Valle
,
Baptiste Martin
,
François Ferron
,
Véronique Roig-Zamboni
,
Aline Desmyter
et al.
Article dans une revue
hal-03334409
v1
|
|
Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers
Florian Gauthier
,
Jean-Rémi Bertrand
,
Jean-Jacques Vasseur
,
Christelle Dupouy
,
Francoise Debart
Article dans une revue
hal-02991729
v1
|
|
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase
Rostom Ahmed‐belkacem
,
Priscila Sutto-Ortiz
,
Mathis Guiraud
,
Bruno Canard
,
Jean-Jacques Vasseur
et al.
Article dans une revue
hal-02890580
v1
|
|
The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation
Coralie Valle
,
Baptiste Martin
,
Francoise Debart
,
Jean-Jacques Vasseur
,
Isabelle Imbert
et al.
Article dans une revue
hal-02890587
v1
|
|
Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome
Konstantinos Boulias
,
Diana Toczydłowska-Socha
,
Ben Hawley
,
Noa Liberman
,
Ken Takashima
et al.
Article dans une revue
hal-02197217
v1
|
|
Conjugation of Small Molecules to RNA Using a Reducible Disulfide Linker Attached at the 2′-OH Position through a Carbamate Function
Florian Gauthier
,
Astrid Malher
,
Jean-Jacques Vasseur
,
Christelle Dupouy
,
Françoise Debart
Article dans une revue
hal-02307249
v1
|
|
FTO controls reversible m6Am RNA methylation during snRNA biogenesis
Jan Mauer
,
Miriam Sindelar
,
Vladimir Despic
,
Théo Guez
,
Benjamin Hawley
et al.
Article dans une revue
hal-02197144
v1
|
|
Synthesis of Adenine Dinucleosides 2′,5′-Bridged by Sulfur-Containing Linkers as Bisubstrate SAM Analogues for Viral RNA 2′- O -Methyltransferases
Rostom Ahmed‐belkacem
,
Priscila Sutto Ortiz
,
Etienne Decroly
,
Jean-Jacques Vasseur
,
Françoise Debart
Article dans une revue
hal-02992283
v1
|
|
Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5′ Caps
Nils Muthmann
,
Théo Guez
,
Jean-Jacques Vasseur
,
Samie Jaffrey
,
Françoise Debart
et al.
Article dans une revue
hal-02197219
v1
|
|
Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2′-position
Florian Gauthier
,
Sandra Claveau
,
Jean-Rémi Bertrand
,
Jean-Jacques Vasseur
,
Christelle Dupouy
et al.
Article dans une revue
hal-02197153
v1
|
|
The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure
Baptiste Martin
,
Bruno Coutard
,
Théo Guez
,
Guido Paesen
,
Bruno Canard
et al.
Article dans une revue
inserm-02416986
v1
|
|
Ebola virus L protein harbors a new enzymatic activity involved in the internal methylation of RNAs
Baptiste Martin
,
Coralie Valle
,
Bruno Coutard
,
Bruno Canard
,
Françoise Debart
et al.
Article dans une revue
hal-02094423
v1
|
|
Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing
Françoise Debart
,
Christelle Dupouy
,
Jean-Jacques Vasseur
Article dans une revue
hal-02197155
v1
|
|
A 2′,2′-disulfide-bridged dinucleotide conformationally locks RNA hairpins
Florian Gauthier
,
Frédéric Beltran
,
Annabelle Biscans
,
Françoise Debart
,
Christelle Dupouy
et al.
Article dans une revue
hal-02197157
v1
|
|
La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region
Lucas Philippe
,
Jean-Jacques Vasseur
,
Françoise Debart
,
Carson Thoreen
Article dans une revue
hal-02197161
v1
|
|
Binding of the Methyl Donor S -Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2′- O -Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10
Wahiba Aouadi
,
Alexandre Blanjoie
,
Jean-Jacques Vasseur
,
Françoise Debart
,
Bruno Canard
et al.
Article dans une revue
hal-01802788
v1
|
|
Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay
Wahiba Aouadi
,
C Ecilia Eydoux
,
Bruno Coutard
,
Baptiste Martin
,
Françoise Debart
et al.
Article dans une revue
hal-02349530
v1
|
|
Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress
Ana Tamarkin-Ben-Harush
,
Jean-Jacques Vasseur
,
Françoise Debart
,
Igor Ulitsky
,
Rivka Dikstein
Article dans une revue
hal-02197213
v1
|
|
Reversible methylation of m6Am in the 5′ cap controls mRNA stability
Jan Mauer
,
Xiaobing Luo
,
Alexandre Blanjoie
,
Xinfu Jiao
,
Anya V Grozhik
et al.
Article dans une revue
hal-02197215
v1
|
|
Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives
Bruno Coutard
,
Karine Barral
,
Julie Lichiere
,
Barbara Selisko
,
Baptiste Martin
et al.
Article dans une revue
hal-01802793
v1
|
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Lipophilic 2′- O -Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery
Annabelle Biscans
,
Jean-Rémi Bertrand
,
Josephine Dubois
,
Jacqueline Rüger
,
Jean-Jacques Vasseur
et al.
Article dans une revue
istex
hal-02197248
v1
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A versatile post-synthetic method on a solid support for the synthesis of RNA containing reduction-responsive modifications
Annabelle Biscans
,
Sonia Rouanet
,
Jean-Jacques Vasseur
,
Christelle Dupouy
,
Françoise Debart
Article dans une revue
hal-02197255
v1
|
|
Synthesis, binding, nuclease resistance and cellular uptake properties of 2′- O -acetalester-modified oligonucleotides containing cationic groups
Annabelle Biscans
,
Sonia Rouanet
,
Jean-Rémi Bertrand
,
Jean-Jacques Vasseur
,
Christelle Dupouy
et al.
Article dans une revue
hal-03554637
v1
|
|
mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research
Changqing Li
,
Jaime Guillen
,
Nadia Rabah
,
Alexandre Blanjoie
,
Francoise Debart
et al.
Article dans une revue
hal-01439035
v1
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|
X-ray structure and activities of an essential Mononegavirales L-protein domain
Guido C. Paesen
,
Axelle Collet
,
Corinne Sallamand
,
Francoise Debart
,
Jean-Jacques Vasseur
et al.
Article dans une revue
hal-01439027
v1
|
|
Solid-Phase Synthesis of Oligonucleotide 5′-(α- P -Thio)triphosphates and 5′-(α- P -Thio)(β,γ-methylene)triphosphates
Yann Thillier
,
Corinne Sallamand
,
Carine Baraguey
,
Jean-Jacques Vasseur
,
Françoise Debart
Article dans une revue
istex
hal-03554798
v1
|
|
mRNA maturation in giant viruses: variation on a theme
Stéphane Priet
,
Audrey Lartigue
,
Françoise Debart
,
Jean-Michel Claverie
,
Chantal Abergel
Article dans une revue
hal-01214084
v1
|
|
Direct Synthesis of Partially Modified 2′-O-Pivaloyloxymethyl RNAs by a Base-Labile Protecting Group Strategy and their Potential for Prodrug-Based Gene-Silencing Applications.
Annabelle Biscans
,
Maxence Bos
,
Anthony R. Martin
,
Nicholas Ader
,
Georg Sczakiel
et al.
Article dans une revue
istex
hal-01101605
v1
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Ecological catalysis and phytoextraction: symbiosis for future
Vincent Escande
,
Laetitia Garoux
,
Claire Grison
,
Yann Thillier
,
Francoise Debart
et al.
Applied Catalysis B: Environmental, 2014, 7th International Conference on Environmental Catalysis (ICEC2012), Lyon, France, 146, pp.279-288. ⟨10.1016/j.apcatb.2013.04.011⟩
Article dans une revue
hal-03177603
v1
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The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure
Carine Lima-Baraguey
,
Eveline Lescrinier
,
Thomas Lavergne
,
Francoise Debart
,
Piet Herdewijn
et al.
Article dans une revue
hal-00805121
v1
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Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates
Jérémie Piton
,
Valéry Larue
,
Yann Thillier
,
Audrey Dorleans
,
Olivier Pellegrini
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (22), pp.8858-8863. ⟨10.1073/pnas.1221510110⟩
Article dans une revue
hal-00829351
v1
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Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.
Karine Barral
,
Corinne Sallamand
,
Christiane Petzold
,
Bruno Coutard
,
Axelle Collet
et al.
Article dans une revue
istex
hal-00874640
v1
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|
Metallophyte wastes and polymetallic catalysis: a promising combination in green chemistry. The illustrative synthesis of 59-capped RNA3
Yann Thillier
,
Guillaume Losfeld
,
Vincent Escande
,
Christelle Dupouy
,
Jean-Jacques Vasseur
et al.
Article dans une revue
hal-03173870
v1
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Solid-phase synthesis of 5′-triphosphate 2′-5′-oligoadenylates analogs with 3′-O-biolabile groups and their evaluation as RNase L activators and antiviral drugs.
Yann Thillier
,
Sarah K Stevens
,
Christabel Moy
,
Taylor Joshua
,
Jean-Jacques Vasseur
et al.
Article dans une revue
istex
hal-00874543
v1
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Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N 7)-methyl transferase
Yann Thillier
,
Etienne Decroly
,
François Morvan
,
Bruno Canard
,
Jean-Jacques Vasseur
et al.
Article dans une revue
hal-00700861
v1
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Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome
Barbara Selisko
,
Supanee Potisopon
,
Rym Agred
,
Stephane Priet
,
Isabelle Varlet
et al.
Article dans une revue
hal-00733199
v1
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FTIR and UV Spectroscopy Studies of Triplex Formation Between Pyrimidine Methoxyethylphosphoramidates α- Oligodeoxynucleotides and ds DNA Targets
Bei-Wen Sun
,
Frédéric Geinguenaud
,
Eliane Taillandier
,
Magali Naval
,
Alain Laurent
et al.
Article dans une revue
hal-04648544
v1
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Synthesis and Preliminary Evaluation of pro-RNA 2'-O-Masked with Biolabile Pivaloyloxymethyl Groups in an RNA Interference Assay
Thomas Lavergne
,
Carine Baraguey
,
Christelle Dupouy
,
N. Parey
,
Winfried Wuensche
et al.
Article dans une revue
hal-00616629
v1
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Efficient solid-phase chemical synthesis of 5'-triphosphates of DNA, RNA and their analogues.
Ivan Zlatev
,
Thomas Lavergne
,
Françoise Debart
,
Jean-Jacques Vasseur
,
Muthiah Manoharan
et al.
Article dans une revue
hal-00519477
v1
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Chemical synthesis of RNA with base-labile 2'-O-(pivaloyloxymethyl)-protected ribonucleoside phosphoramidites.
Thomas Lavergne
,
Michaël Janin
,
Christelle Dupouy
,
Jean-Jacques Vasseur
,
Françoise Debart
Article dans une revue
hal-00556631
v1
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From anionic to cationic alpha-anomeric oligodeoxynucleotides.
François Morvan
,
Françoise Debart
,
Jean-Jacques Vasseur
Article dans une revue
istex
hal-00476462
v1
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Efficient release of base-sensitive oligonucleotides from solid supports using fluoride ions.
T. Lavergne
,
N. Parey
,
J.-J. Vasseur
,
F. Debart
Article dans une revue
hal-00376886
v1
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Assessment of new 2'-O-acetalester protecting groups for regular RNA synthesis and original 2'-modified proRNA.
Anthony R. Martin
,
Thomas Lavergne
,
Jean-Jacques Vasseur
,
Françoise Debart
Article dans une revue
istex
hal-00412360
v1
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A base labile group for 2'-OH protection of ribonucleosides : as a major challenge for RNA synthesis.
T. Lavergne
,
J.-R. Bertrand
,
J.-J. Vasseur
,
F. Debart
Article dans une revue
istex
hal-00346580
v1
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5-propynylamino alpha-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic alpha-oligonucleotides.
Gaëlle Deglane
,
François Morvan
,
Françoise Debart
,
Jean-Jacques Vasseur
Article dans une revue
istex
hal-00137368
v1
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Chemical modifications to improve the cellular uptake of oligonucleotides.
Françoise Debart
,
Saïd Abes
,
Gaelle Deglane
,
Hong M Moulton
,
Philippe Clair
et al.
Article dans une revue
istex
hal-00150534
v1
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Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding.
Allison A. Johnson
,
Jane M. Sayer
,
Haruhiko Yagi
,
Sachindra S. Patil
,
Françoise Debart
et al.
Journal of Biological Chemistry, 2006, 281 (43), pp.32428-32438
Article dans une revue
hal-00109066
v1
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Impact of the guanidinium group on hybridization and cellular uptake of cationic oligonucleotides.
Gaëlle Deglane
,
Said Abes
,
Thibaud Michel
,
Paul Prevot
,
Eric Vivès
et al.
ChemBioChem, 2006, 7, pp.684-692
Article dans une revue
hal-00022245
v1
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First evaluation of acyloxymethyl or acylthiomethyl groups as biolabile 2'-O-protections of RNA.
Nora Parey
,
Carine Baraguey
,
Jean-Jacques Vasseur
,
Françoise Debart
Organic Letters, 2006, 8, pp.3869-3872
Article dans une revue
hal-00097408
v1
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Highly Stable DNA Triplexes Formed with Cationic Phosphoramidate Pyrimidine α‐Oligonucleotides
Thibaut Michel
,
Francoise Debart
,
Frédéric Heitz
,
Jean-Jacques Vasseur
Article dans une revue
hal-04600743
v1
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Toward high yield synthesis of peptide–oligonucleotide chimera through a disulfide bridge: A simplified method for oligonucleotide activation
Frédéric Maurel
,
Françoise Debart
,
Florine Cavelier
,
Alain Thierry
,
Bernard Lebleu
et al.
Article dans une revue
istex
hal-03824545
v1
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Cationic phosphoramidate -oligonucleotides efficiently target single-stranded DNA and RNA and inhibit hepatitis C virus IRES-mediated translation
Thibaut Michel
,
Camille Martinand-Mari
,
Francoise Debart
,
Bernard Lebleu
,
Ian Robbins
et al.
Article dans une revue
hal-01878566
v1
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Efficient guanidination of the phosphate linkage towards cationic phosphoramidate oligonucleotides
Thibaut Michel
,
Francoise Debart
,
Jean-Jacques Vasseur
Article dans une revue
hal-04600871
v1
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FTIR and UV Spectroscopy Studies of Triplex Formation Between α-Oligonucleotides with Non-Ionic Phoshoramidate Linkages and DNA Targets
Thibault Michel
,
Francoise Debart
,
Jean-Jacques Vasseur
,
Frédéric Geinguenaud
,
Eliane Taillandier
Article dans une revue
hal-04648468
v1
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Synthesis, DNA binding and biological evaluation of synthetic precursors and novel analogs of netropsin
Francoise Debart
,
Christian Périgaud
,
Gilles Gosselin
,
Driss Mrani
,
Bernard Rayner
et al.
Article dans une revue
istex
hal-04652355
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2-Amino-α-2′-deoxyadenosine increased duplex stability of methoxyethylphosphoramidate α-Oligodeoxynucleotides with RNA target
Magali Naval
,
Thibaut Michel
,
Jean-Jacques Vasseur
,
Francoise Debart
Article dans une revue
hal-04600717
v1
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Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides
T Guerlavais
,
Albert Meyer
,
Francoise Debart
,
J-L Imbach
,
François Morvan
et al.
Article dans une revue
hal-04600638
v1
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Chiral and steric effects in the efficient binding of α α α α-anomeric deoxyoligonucleoside N-alkylphosphoramidates to ssDNA and RNA
A. Laurent
,
Magali Naval
,
Françoise Debart
,
J.J. Vasseur
,
Bernard Rayner
Article dans une revue
hal-03008441
v1
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Anomeric inversion (from β to α) in methylphosphonate oligonucleosides enhances their affinity for DNA and RNA
Françoise Debart
,
Albert Meyer
,
J.J. Vasseur
,
Bernard Rayner
Article dans une revue
hal-03008434
v1
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A new route to oligodeoxynucleoside phosphoramidates (PNH2)
Alain Laurent
,
Francoise Debart
,
Bernard Rayner
Article dans une revue
istex
hal-04648599
v1
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Esterase-triggered fluorescence of fluorogenic oligonucleotides
Alain Laurent
,
Francoise Debart
,
Ned J. Lamb
,
Bernard Rayner
Article dans une revue
hal-04600699
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Chimeric alpha‐beta oligonucleotides as antisense inhibitors of reverse transcription
Claudine Boiziau
,
Françoise Debart
,
Bernard Rayner
,
Jean-Louis Imbach
,
Jean-Jacques Toulme
Article dans une revue
istex
hal-04650399
v1
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Optimization of hybridizing abilities and nuclease resistance in the design of chimeric α-anomeric oligodeoxynucleotides containing β-anomeric gaps
Francoise Debart
,
Guilhem Tosquellas
,
Bernard Rayner
,
Jean-Louis Imbach
Article dans une revue
istex
hal-04651101
v1
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Efficient and Stereoselective Synthesis of 3′-Deoxy 3′ - C -Branched-Chain Substituted Thymidine
Yogesh Sanghvi
,
Ramesh Bharadwaj
,
Francoise Debart
,
Alain de Mesmaeker
Article dans une revue
hal-04650441
v1
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Synthesis and base-pairing properties of the nuclease-resistant α-anomeric dodecaribonucleotide α-[r(UCUUAACCCACA)]
Francoise Debart
,
Bernard Rayner
,
Genevieve Degols
,
Jean-Louis Imbach
Article dans une revue
hal-04651171
v1
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Intermolecular radical C-C bond formation: Synthesis of a novel dinucleoside linker for non-anionic antisense oligonucleosides
Francoise Debart
,
Jean-Jacques Vasseur
,
Yogesh Sanghvi
,
P. Dan Cook
Article dans une revue
istex
hal-04651127
v1
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Synthesis and incorporation of methyleneoxy(methylimino) linked thymidine dimer into antisense oligonucleosides
Francoise Debart
,
Jean-Jacques Vasseur
,
Yogesh Sanghvi
,
P. Dan Cook
Article dans une revue
istex
hal-04651150
v1
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Caractérisation de nouveaux dérivés et analogues de la nétropsine et identification de leurs intermédiaires de synthèse par spectrométrie de masse FAB
Jean‐Louis Aubagnac
,
Francoise Debart
,
Driss Mrani
,
Gilles Gosselin
,
Bernard Rayner
et al.
Article dans une revue
istex
hal-04600793
v1
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Synthesis, DNA binding properties and biological evaluation of novel oligo-meta-benzamides related to netropsin
Francoise Debart
,
Gilles Gosselin
,
Bernard Rayner
,
P Le Ber
,
C Auclair
et al.
Article dans une revue
hal-04651228
v1
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Sugar modified oligonucleotides : II. Solid phase synthesis of nuclease resistant α-anomeric uridylates as potential antisense agents
Francoise Debart
,
Bernard Rayner
,
Jeon-Louis Imbach
Article dans une revue
istex
hal-04600829
v1
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Structure and Conformation of the Duplex Consensus 5′-Splice Site d [(CpApGpGpTpApApGpT) (ApCpTpTpApCpCpTpG)] Deduced from High Field 1 H-NMR of the Non-Exchangeable and Imino Protons
Francoise Debart
,
Bernard Rayner
,
Jean-Louis Imbach
,
Moses Lee
,
Ding-Kwo Chang
et al.
Article dans une revue
hal-04652389
v1
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Structure and Conformation of the Duplex Consensus Acceptor Exon: Intron Junction d [(CpTpApCpApGpGpT) (ApCpCpTpGpTpApG)] deduced from High-Field 1 H-NMR of Non-Exchangeable and Imino Protons
Francoise Debart
,
Bernard Rayner
,
Jean-Louis Imbach
,
Ding-Kwo Chang
,
J. William Lown
Article dans une revue
hal-04652415
v1
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1 H and 31 P-NMR Assignments of the Non-exchangeable Protons of the Consensus Acceptor Exon: Intron Junction d(CpTpApCpApGpGpT)
J. William Lown
,
Ding-Kwo Chang
,
Francoise Debart
,
Bernard Rayner
,
Jean-Louis Imbach
Article dans une revue
hal-04652404
v1
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