Frédéric Derbré

46
Documents

Publications

Publications

Extreme physical inactivity alters iron metabolism: mechanisms and health issues for astronauts and bedridden patients

Mathieu Horeau , Maelys Auffret , Olivier Loréal , Frédéric Derbré

The Journal of Physiology, 2025, ⟨10.1113/jp289149⟩

Article dans une revue hal-05353916v1
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Atypical gut microbial ecosystem from athletes with very high exercise capacity improves insulin sensitivity and muscle glycogen store in mice

David Martin , Mathis Bonneau , Luz Orfila , Mathieu Horeau , Mathilde Hazon et al.

Cell Reports, 2025, 44 (4), pp.115448. ⟨10.1016/j.celrep.2025.115448⟩

Article dans une revue hal-05033053v1
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A conceptual framework for revealing rare bacterial species in the gut microbiome through guided data transformation: Beyond enterotypes

David Martin , Pierre Houedry , Frederic Derbré , Valérie Monbet

Methods in Ecology and Evolution, 2025, ⟨10.1111/2041-210x.70223⟩

Article dans une revue hal-05421483v1
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Dry immersion rapidly disturbs iron metabolism in men and women: results from the VIVALDI studies

Mathieu Horeau , Nastassia Navasiolava , Angelique van Ombergen , Marc-Antoine Custaud , Adrien Robin et al.

NPJ Microgravity, 2024, 10 (1), pp.68. ⟨10.1038/s41526-024-00399-z⟩

Article dans une revue hal-04650054v1
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The Yucatan minipig model: A new preclinical model of malnutrition in obese patients with acute or chronic diseases

Annaëlle Couvert , Laurence Lacaze , Steve Touboulic , Sandrine Gautier , Sylvie Guerin et al.

Clinical Nutrition, 2024, Clinical Nutrition (edinburgh, Scotland), 43 (2), pp.357-365. ⟨10.1016/j.clnu.2023.12.003⟩

Article dans une revue hal-04415280v1
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Iron Metabolism Regulation in Females and Males Exposed to Simulated Microgravity: results from the Randomized Trial AGBRESA

Mathieu Horeau , Martine Ropert , Edwin Mulder , Jens Tank , Petra Frings-Meuthen et al.

The American Journal of Clinical Nutrition, 2022, 116 (5), pp.1430-1440. ⟨10.1093/ajcn/nqac205⟩

Article dans une revue hal-03777172v1
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Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload

David Martin , Kévin Nay , François Robin , Amélie Rebillard , Luz Orfila et al.

Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (2), pp.1250-1261. ⟨10.1002/jcsm.12897⟩

Article dans une revue hal-03564762v1
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Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model

Maxence Jollet , Kevin Nay , Angèle Chopard , Marie-Pierre Bareille , Arnaud Beck et al.

Nutrients, 2021, 13 (11), ⟨10.3390/nu13113865⟩

Article dans une revue hal-03415988v1
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Métabolisme du fer : impact de l'hypoactivité et mécanismes sous-jacents

K. Nay , M. Horeau , Olivier Loréal , F. Derbré

Cahiers de Nutrition et de Diététique, 2021, 56 (2), pp.131-140. ⟨10.1016/j.cnd.2021.01.002⟩

Article dans une revue hal-03225511v1
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Simulated microgravity disturbs iron metabolism and distribution in humans: Lessons from dry immersion, an innovative ground-based human model

Kevin Nay , Christelle Koechlin Ramonatxo , Rochdi Sarraj , Marie-Laure Island , Luz Orfila et al.

FASEB Journal, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩

Article dans une revue hal-02946797v1
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Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia

Moussa Kenawi , Emmanuel Rouger , Marie-Laure Island , Patricia Leroyer , François Robin et al.

FASEB Journal, 2019, 44093 (12), pp.fj201901106R. ⟨10.1096/fj.201901106R⟩

Article dans une revue hal-02307161v1
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Gut bacteria are critical for optimal muscle functiona potential link with glucose homeostasis

Kevin Nay , Maxence Jollet , Benedicte Goustard , Narjes Baati , Barbara Vernus et al.

AJP - Endocrinology and Metabolism, 2019, 317 (1), pp.E158-E171. ⟨10.1152/ajpendo.00521.2018⟩

Article dans une revue hal-02152871v1

Effects of intermittent muscle reconditioning on alterations of iron distribution and availability during simulated microgravity

David J. R. Martin , Kevin Nay , Luz Orfila , Dany Saligaut , Moussa Kenawy et al.

Acta Physiologica, 2019, 227

Article dans une revue hal-02393440v1
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Skeletal muscle ceramides do not contribute to physical inactivity-induced insulin resistance

Zéphyra Appriou , Kevin Nay , Nicolas Pierre , Dany Saligaut , Luz Lefeuvre-Orfila et al.

Applied Physiology, Nutrition, and Metabolism, 2019, 44 (11), pp.1180-1188. ⟨10.1139/apnm-2018-0850⟩

Article dans une revue hal-02087899v1
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Allopurinol partially prevents disuse muscle atrophy in mice and humans

Beatriz Ferrando , Mari Carmen Gomez-Cabrera , Andrea Salvador-Pascual , Carlos Puchades , Frédéric Derbré et al.

Scientific Reports, 2018, 8 (1), pp.3549. ⟨10.1038/s41598-018-21552-1⟩

Article dans une revue hal-01744457v1
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Simulated microgravity decreases circulating iron in rats: role of inflammation-induced hepcidin upregulation

Thibault Cavey , Nicolas Pierre , Kevin Nay , Coralie Allain , Martine Ropert et al.

Experimental Physiology, 2017, 102 (3), pp.291-298. ⟨10.1113/EP086188⟩

Article dans une revue hal-01483855v1

The diaphragm is better protected from oxidative stress than hindlimb skeletal muscle during CLP-induced sepsis

Hélène Talarmin , Frédéric Derbré , Luz Lefeuvre-Orfila , Karelle Léon , Mickaël Droguet et al.

Redox Report, 2017, 22 (5), pp.218-226. ⟨10.1080/13510002.2016.1223793⟩

Article dans une revue hal-01586183v1

Maintaining a regular physical activity aggravates intramuscular tumor growth in an orthotopic liposarcoma model

Mohamad Assi , Frédéric Derbré , Luz Lefeuvre-Orfila , Dany Saligaut , Nathalie Stock et al.

American Journal of Cancer Research, 2017, 7 (5), pp.1037--1053

Article dans une revue hal-01544192v1
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The Oxygen Paradox, the French Paradox, and age-related diseases

Joanna M. S. Davies , Josiane Cillard , Bertrand Friguet , Enrique Cadenas , Jean Cadet et al.

GeroScience, 2017, 39 (5-6), pp.499-550. ⟨10.1007/s11357-017-0002-y⟩

Article dans une revue hal-01718093v1
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Antioxidant supplementation accelerates cachexia development by promoting tumor growth in C26 tumor-bearing mice

Mohamad Assi , Frédéric Derbré , Luz Lefeuvre-Orfila , Amélie Rébillard

Free Radical Biology and Medicine, 2016, 91, pp.204-214. ⟨10.1016/j.freeradbiomed.2015.12.019⟩

Article dans une revue hal-01255843v1
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From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy

Nicolas Pierre , Zéphyra Appriou , Arlette Gratas-Delamarche , Frédéric Derbré

Free Radical Biology and Medicine, 2016, 98, pp.197-207. ⟨10.1016/j.freeradbiomed.2015.12.028⟩

Article dans une revue hal-01255823v1

Myriocin prevents muscle ceramide accumulation, but not muscle fiber atrophy during short-term mechanical unloading

Erwann Salaun , Luz Lefeuvre-Orfila , Thibault Cavey , Brice Martin , Bruno Turlin et al.

Journal of Applied Physiology, 2016, 120 (2), pp.178-187. ⟨10.1152/japplphysiol.00720.2015⟩

Article dans une revue hal-01231413v1

Single Muscle Immobilization Decreases Single-Fibre Myosin Heavy Chain Polymorphism: Possible Involvement of p38 and JNK MAP Kinases

Frédéric Derbré , Mickaël Droguet , Karelle Léon , Samuel Troadec , Jean-Pierre Pennec et al.

PLoS ONE, 2016, 11 (7), pp.e0158630. ⟨10.1371/journal.pone.0158630⟩

Article dans une revue hal-01397593v1

Physical inactivity, insulin resistanceand the oxidative-inflammatory loop

Arlette Gratas-Delamarche , Frédéric Derbré , Sophie Vincent , Josiane Cillard

Free Radic Res., 2014, 48 (1), pp.93-108. ⟨10.3109/10715762.2013.847528⟩

Article dans une revue hal-01159356v1

Mitochondrial fission and fusion in human diseases.

F Sanchis-Gomar , Frédéric Derbré

New England Journal of Medicine, 2014, 370 (11), pp.1073-4. ⟨10.1056/NEJMc1316254#SA1⟩

Article dans une revue hal-01159338v1

Inhibition of Xanthine Oxidase by Allopurinol Prevents Skeletal Muscle Atrophy: Role of p38 MAPKinase and E3 Ubiquitin Ligases

Frédéric Derbré , B Ferrando , Mc Gómez-Cabrera , F Sanchis-Gomar , Ve Martinez-Bello et al.

PLoS ONE, 2012, e46668, pp.e46668. ⟨10.1371/journal.pone.0046668⟩

Article dans une revue hal-01159428v1

Inactivity-induced oxidative stress: A central role in age-related sarcopenia?

Frédéric Derbré , Arlette Gratas-Delamarche , M.C. Gomez-Cabrera , José Viña

European Journal of Sport Science, 2012, 14 Suppl 1, pp.S98-108. ⟨10.1080/17461391.2011.654268⟩

Article dans une revue hal-01159426v1

Age associated low mitochondrial biogenesis may be explained by lack of response of PGC-1alpha to exercise training

Frédéric Derbré , M C Gomez-Cabrera , a L Nascimento , F Sanchis-Gomar , V E Martinez-Bello et al.

AGE, 2012, 34 (3), pp.669-679. ⟨10.1007/s11357-011-9264-y⟩

Article dans une revue hal-01159427v1

Rapid hemodilution induced by desmopressin after erythropoietin administration in humans

F Sanchis Gomar , Ve Martinez Bello , Frédéric Derbré , E Garcia Lopez , R Garcia Valles et al.

Journal of Human Sport and Exercise, 2011, 6 (2), pp.1-8. ⟨10.4100/jhse.2011.62.12⟩

Article dans une revue hal-01159461v1

Androgens responses to sprint exercise in young men

Paul Delamarche , Arlette Delamarche , Frédéric Derbré , Maitel Botcazou , Serge Vincent et al.

International Journal of Sports Medicine, 2010, 5 (31), pp.291-297

Article dans une revue halshs-00649696v1

Androgen Responses to Sprint Exercise in Young Men

Frédéric Derbré , Serge Vincent , Maitel Botcazou , Christian Jacob , Paul Delamarche et al.

International Journal of Sports Medicine, 2010, 5 (31), pp.291-297

Article dans une revue halshs-00651190v1

Effects of sprint training and detraining on plasma volume variations induced by supramaximal exercise in adolescent boys

Frédéric Derbré , Maitel Botcazou , Serge Vincent , Christian Jacob , Paul Delamarche et al.

Science & Sports, 2009, 24, pp.166-172

Article dans une revue halshs-00649850v1

Effets de l'entraînement de sprint et du désentraînement sur les variations du volume plasmatique induites par un test supramaximal chez des adolescents

Frédéric Derbré , Maitel Botcazou , C. Jacob , V Sophie , A. Ben Abderrahmane et al.

Science & Sports, 2009, 24 (2), pp.166-172

Article dans une revue halshs-00651507v1

Iron metabolism is differently regulated depending on muscle fiber phenotype

David J. R. Martin , Kevin Nay , François Robin , Gevorg Ghukasyan , Suzanne Dufresne et al.

3. Congress of Physiology and Integrative Biology (CPBI) ; 86. Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. WILEY, Acta Physiologica, 227 (Supp 720), 2019, Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP)

Poster de conférence hal-02734839v1

Gut bacteria are critical for optimal muscle function: a potential link with glucose homeostasis

Kevin Nay , Maxence Jollet , Benedicte Goustard , Barbara Vernus , Luz Lefeuvre et al.

3. Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. Wiley, Acta Physiologica, 227, 2019, Special Issue:Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP)

Poster de conférence hal-02735731v1

Effects of intermittent muscle reconditioning on alterations of iron distribution and availability during simulated microgravity

David J. R. Martin , Kevin Nay , Luz Orfila , Dany Saligaut , Moussa Kenawy et al.

3. Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. John Wiley and Sons, Acta Physiologica, 227, 2019, Special Issue: Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP)

Poster de conférence hal-02734867v1

Modulation of skeletal muscle function by gut Microbiota Dysbiosis and reseeding

Kevin Nay , Maxence Jollet , Bénédicte Goustard , Barbara Vernus , Anne Bonnieu et al.

European College of Sport Science, Jul 2018, Dublin, Ireland

Communication dans un congrès hal-03753298v1

Modulation of skeletal muscle function by gut microbiota dysbiosis and reseeding

Kevin Nay , Maxence Jollet , Bénédicte Goustard , Narjes Baati , Barbara Vernus et al.

5. World Congress on Targeting Microbiota, Oct 2017, Berlin, Germany

Communication dans un congrès hal-03753288v1

OP17 - Natural antioxidants accelerate cachexia development in colon cancer

Mohamad Assi , Frédéric Derbré , Luz Lefeuvre-Orfila , Amélie Rébillard

SFRR-E/SNFS, 2015, Stuttgart, Germany. pp.S9--S10, ⟨10.1016/j.freeradbiomed.2015.07.044⟩

Communication dans un congrès istex hal-01198637v1

Effects of Galacto-oligosaccharides (GOS) on skeletal muscle atrophy, oxidative stress and inflammation in streptozotocin-diabetic rats.

Beatriz Ferrando , Frédéric Derbré , Sophie Vincent , Carole Groussard , Luz Lefeuvre-Orfila et al.

18th Annual Congress of the European College of Sport Sciences, Barcelone, Spain, 26-29 juin., 2013, Barcelone, Spain

Communication dans un congrès hal-01159361v1

Effects of Galacto-oligosaccharides (GOS) and training on immune cells in streptozotocin-diabetic rats

Sophie Vincent , Luz Lefeuvre-Orfila , Carole Groussard , Frédéric Derbré , Dany Saligaut et al.

18th Annual Congress of the European College of Sport Sciences, Barcelone, Spain, 26-29 juin., 2013, Barcelone, Spain

Communication dans un congrès hal-01159378v1

Coloration des fibres de réticuline sur tissu musculaire par la méthode de Gomori : intérêts pour l'étude de l'atrophie musculaire.

Frédéric Derbré , P Bellaud , A Fautrel , Amélie Rébillard

Congrès de l'Association Française d'Histotechnologie, 13-14 juin 2013, Rennes., 2013, Rennes, France

Communication dans un congrès hal-01159364v1

Skeletal muscle regeration during aging and physical exercise : role of oxidative stress and myostatin

Frédéric Derbré , Mari-Carmen Gomez-Cabrera , Ana Nascimiento , Vladimir Martinez-Bello , Fabian Sanchis-Gomar et al.

15th Annual Congress of the European College of Sport Science, 2010, Antalya, Turkey

Communication dans un congrès hal-01159498v1

Bénéfices de l'allopurinol dans la prévention de l'atrophie musculaire induite par l'immobilisation

Frédéric Derbré , B Ferrando , V Martinez-Bello , F Sanchis-Gomar , Garcia-Valles R et al.

Congrès P2T, 2010, Grenoble, France

Communication dans un congrès hal-01159493v1