Frédéric Derbré

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Publications

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Atypical gut microbial ecosystem from athletes with very high exercise capacity improves insulin sensitivity and muscle glycogen store in mice

David Martin , Mathis Bonneau , Luz Orfila , Mathieu Horeau , Mathilde Hazon et al.

Cell Reports, 2025, 44 (4), pp.115448. ⟨10.1016/j.celrep.2025.115448⟩

Article dans une revue hal-05033053v1

Extreme physical inactivity alters iron metabolism: mechanisms and health issues for astronauts and bedridden patients

Mathieu Horeau , Maelys Auffret , Olivier Loréal , Frédéric Derbré

The Journal of Physiology, 2025, ⟨10.1113/jp289149⟩

Article dans une revue hal-05353916v1
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The Yucatan minipig model: A new preclinical model of malnutrition in obese patients with acute or chronic diseases

Annaëlle Couvert , Laurence Lacaze , Steve Touboulic , Sandrine Gautier , Sylvie Guerin et al.

Clinical Nutrition, 2024, Clinical Nutrition (edinburgh, Scotland), 43 (2), pp.357-365. ⟨10.1016/j.clnu.2023.12.003⟩

Article dans une revue hal-04415280v1
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Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload

David Martin , Kévin Nay , François Robin , Amélie Rebillard , Luz Orfila et al.

Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (2), pp.1250-1261. ⟨10.1002/jcsm.12897⟩

Article dans une revue hal-03564762v1
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Iron Metabolism Regulation in Females and Males Exposed to Simulated Microgravity: results from the Randomized Trial AGBRESA

Mathieu Horeau , Martine Ropert , Edwin Mulder , Jens Tank , Petra Frings-Meuthen et al.

The American Journal of Clinical Nutrition, 2022, 116 (5), pp.1430-1440. ⟨10.1093/ajcn/nqac205⟩

Article dans une revue hal-03777172v1
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Métabolisme du fer : impact de l'hypoactivité et mécanismes sous-jacents

K. Nay , M. Horeau , Olivier Loréal , F. Derbré

Cahiers de Nutrition et de Diététique, 2021, 56 (2), pp.131-140. ⟨10.1016/j.cnd.2021.01.002⟩

Article dans une revue hal-03225511v1
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Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model

Maxence Jollet , Kevin Nay , Angèle Chopard , Marie-Pierre Bareille , Arnaud Beck et al.

Nutrients, 2021, 13 (11), ⟨10.3390/nu13113865⟩

Article dans une revue hal-03415988v1
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Simulated microgravity disturbs iron metabolism and distribution in humans: Lessons from dry immersion, an innovative ground-based human model

Kevin Nay , Christelle Koechlin Ramonatxo , Rochdi Sarraj , Marie-Laure Island , Luz Orfila et al.

FASEB Journal, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩

Article dans une revue hal-02946797v1
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Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia

Moussa Kenawi , Emmanuel Rouger , Marie-Laure Island , Patricia Leroyer , François Robin et al.

FASEB Journal, 2019, 44093 (12), pp.fj201901106R. ⟨10.1096/fj.201901106R⟩

Article dans une revue hal-02307161v1
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Gut bacteria are critical for optimal muscle functiona potential link with glucose homeostasis

Kevin Nay , Maxence Jollet , Benedicte Goustard , Narjes Baati , Barbara Vernus et al.

AJP - Endocrinology and Metabolism, 2019, 317 (1), pp.E158-E171. ⟨10.1152/ajpendo.00521.2018⟩

Article dans une revue hal-02152871v1

Effects of intermittent muscle reconditioning on alterations of iron distribution and availability during simulated microgravity

David J. R. Martin , Kevin Nay , Luz Orfila , Dany Saligaut , Moussa Kenawy et al.

Acta Physiologica, 2019, 227

Article dans une revue hal-02393440v1
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Skeletal muscle ceramides do not contribute to physical inactivity-induced insulin resistance

Zéphyra Appriou , Kevin Nay , Nicolas Pierre , Dany Saligaut , Luz Lefeuvre-Orfila et al.

Applied Physiology, Nutrition, and Metabolism, 2019, 44 (11), pp.1180-1188. ⟨10.1139/apnm-2018-0850⟩

Article dans une revue hal-02087899v1
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Allopurinol partially prevents disuse muscle atrophy in mice and humans

Beatriz Ferrando , Mari Carmen Gomez-Cabrera , Andrea Salvador-Pascual , Carlos Puchades , Frédéric Derbré et al.

Scientific Reports, 2018, 8 (1), pp.3549. ⟨10.1038/s41598-018-21552-1⟩

Article dans une revue hal-01744457v1
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The Oxygen Paradox, the French Paradox, and age-related diseases

Joanna M. S. Davies , Josiane Cillard , Bertrand Friguet , Enrique Cadenas , Jean Cadet et al.

GeroScience, 2017, 39 (5-6), pp.499-550. ⟨10.1007/s11357-017-0002-y⟩

Article dans une revue hal-01718093v1
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Simulated microgravity decreases circulating iron in rats: role of inflammation-induced hepcidin upregulation

Thibault Cavey , Nicolas Pierre , Kevin Nay , Coralie Allain , Martine Ropert et al.

Experimental Physiology, 2017, 102 (3), pp.291-298. ⟨10.1113/EP086188⟩

Article dans une revue hal-01483855v1

The diaphragm is better protected from oxidative stress than hindlimb skeletal muscle during CLP-induced sepsis

Hélène Talarmin , Frédéric Derbré , Luz Lefeuvre-Orfila , Karelle Léon , Mickaël Droguet et al.

Redox Report, 2017, 22 (5), pp.218-226. ⟨10.1080/13510002.2016.1223793⟩

Article dans une revue hal-01586183v1

Maintaining a regular physical activity aggravates intramuscular tumor growth in an orthotopic liposarcoma model

Mohamad Assi , Frédéric Derbré , Luz Lefeuvre-Orfila , Dany Saligaut , Nathalie Stock et al.

American Journal of Cancer Research, 2017, 7 (5), pp.1037--1053

Article dans une revue hal-01544192v1

Single Muscle Immobilization Decreases Single-Fibre Myosin Heavy Chain Polymorphism: Possible Involvement of p38 and JNK MAP Kinases

Frédéric Derbré , Mickaël Droguet , Karelle Léon , Samuel Troadec , Jean-Pierre Pennec et al.

PLoS ONE, 2016, 11 (7), pp.e0158630. ⟨10.1371/journal.pone.0158630⟩

Article dans une revue hal-01397593v1
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From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy

Nicolas Pierre , Zéphyra Appriou , Arlette Gratas-Delamarche , Frédéric Derbré

Free Radical Biology and Medicine, 2016, 98, pp.197-207. ⟨10.1016/j.freeradbiomed.2015.12.028⟩

Article dans une revue hal-01255823v1

Myriocin prevents muscle ceramide accumulation, but not muscle fiber atrophy during short-term mechanical unloading

Erwann Salaun , Luz Lefeuvre-Orfila , Thibault Cavey , Brice Martin , Bruno Turlin et al.

Journal of Applied Physiology, 2016, 120 (2), pp.178-187. ⟨10.1152/japplphysiol.00720.2015⟩

Article dans une revue hal-01231413v1
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Antioxidant supplementation accelerates cachexia development by promoting tumor growth in C26 tumor-bearing mice

Mohamad Assi , Frédéric Derbré , Luz Lefeuvre-Orfila , Amélie Rébillard

Free Radical Biology and Medicine, 2016, 91, pp.204-214. ⟨10.1016/j.freeradbiomed.2015.12.019⟩

Article dans une revue hal-01255843v1

Mitochondrial fission and fusion in human diseases.

F Sanchis-Gomar , Frédéric Derbré

New England Journal of Medicine, 2014, 370 (11), pp.1073-4. ⟨10.1056/NEJMc1316254#SA1⟩

Article dans une revue hal-01159338v1

Physical inactivity, insulin resistanceand the oxidative-inflammatory loop

Arlette Gratas-Delamarche , Frédéric Derbré , Sophie Vincent , Josiane Cillard

Free Radic Res., 2014, 48 (1), pp.93-108. ⟨10.3109/10715762.2013.847528⟩

Article dans une revue hal-01159356v1

Inhibition of Xanthine Oxidase by Allopurinol Prevents Skeletal Muscle Atrophy: Role of p38 MAPKinase and E3 Ubiquitin Ligases

Frédéric Derbré , B Ferrando , Mc Gómez-Cabrera , F Sanchis-Gomar , Ve Martinez-Bello et al.

PLoS ONE, 2012, e46668, pp.e46668. ⟨10.1371/journal.pone.0046668⟩

Article dans une revue hal-01159428v1

Age associated low mitochondrial biogenesis may be explained by lack of response of PGC-1alpha to exercise training

Frédéric Derbré , M C Gomez-Cabrera , a L Nascimento , F Sanchis-Gomar , V E Martinez-Bello et al.

AGE, 2012, 34 (3), pp.669-679. ⟨10.1007/s11357-011-9264-y⟩

Article dans une revue hal-01159427v1

Inactivity-induced oxidative stress: A central role in age-related sarcopenia?

Frédéric Derbré , Arlette Gratas-Delamarche , M.C. Gomez-Cabrera , José Viña

European Journal of Sport Science, 2012, 14 Suppl 1, pp.S98-108. ⟨10.1080/17461391.2011.654268⟩

Article dans une revue hal-01159426v1

Rapid hemodilution induced by desmopressin after erythropoietin administration in humans

F Sanchis Gomar , Ve Martinez Bello , Frédéric Derbré , E Garcia Lopez , R Garcia Valles et al.

Journal of Human Sport and Exercise, 2011, 6 (2), pp.1-8. ⟨10.4100/jhse.2011.62.12⟩

Article dans une revue hal-01159461v1

Androgens responses to sprint exercise in young men

Paul Delamarche , Arlette Delamarche , Frédéric Derbré , Maitel Botcazou , Serge Vincent et al.

International Journal of Sports Medicine, 2010, 5 (31), pp.291-297

Article dans une revue halshs-00649696v1

Androgen Responses to Sprint Exercise in Young Men

Frédéric Derbré , Serge Vincent , Maitel Botcazou , Christian Jacob , Paul Delamarche et al.

International Journal of Sports Medicine, 2010, 5 (31), pp.291-297

Article dans une revue halshs-00651190v1

Effects of sprint training and detraining on plasma volume variations induced by supramaximal exercise in adolescent boys

Frédéric Derbré , Maitel Botcazou , Serge Vincent , Christian Jacob , Paul Delamarche et al.

Science & Sports, 2009, 24, pp.166-172

Article dans une revue halshs-00649850v1

Effets de l'entraînement de sprint et du désentraînement sur les variations du volume plasmatique induites par un test supramaximal chez des adolescents

Frédéric Derbré , Maitel Botcazou , C. Jacob , V Sophie , A. Ben Abderrahmane et al.

Science & Sports, 2009, 24 (2), pp.166-172

Article dans une revue halshs-00651507v1

Modulation of skeletal muscle function by gut Microbiota Dysbiosis and reseeding

Kevin Nay , Maxence Jollet , Bénédicte Goustard , Barbara Vernus , Anne Bonnieu et al.

European College of Sport Science, Jul 2018, Dublin, Ireland

Communication dans un congrès hal-03753298v1

Modulation of skeletal muscle function by gut microbiota dysbiosis and reseeding

Kevin Nay , Maxence Jollet , Bénédicte Goustard , Narjes Baati , Barbara Vernus et al.

5. World Congress on Targeting Microbiota, Oct 2017, Berlin, Germany

Communication dans un congrès hal-03753288v1

OP17 - Natural antioxidants accelerate cachexia development in colon cancer

Mohamad Assi , Frédéric Derbré , Luz Lefeuvre-Orfila , Amélie Rébillard

SFRR-E/SNFS, 2015, Stuttgart, Germany. pp.S9--S10, ⟨10.1016/j.freeradbiomed.2015.07.044⟩

Communication dans un congrès istex hal-01198637v1

Effects of Galacto-oligosaccharides (GOS) on skeletal muscle atrophy, oxidative stress and inflammation in streptozotocin-diabetic rats.

Beatriz Ferrando , Frédéric Derbré , Sophie Vincent , Carole Groussard , Luz Lefeuvre-Orfila et al.

18th Annual Congress of the European College of Sport Sciences, Barcelone, Spain, 26-29 juin., 2013, Barcelone, Spain

Communication dans un congrès hal-01159361v1

Effects of Galacto-oligosaccharides (GOS) and training on immune cells in streptozotocin-diabetic rats

Sophie Vincent , Luz Lefeuvre-Orfila , Carole Groussard , Frédéric Derbré , Dany Saligaut et al.

18th Annual Congress of the European College of Sport Sciences, Barcelone, Spain, 26-29 juin., 2013, Barcelone, Spain

Communication dans un congrès hal-01159378v1

Coloration des fibres de réticuline sur tissu musculaire par la méthode de Gomori : intérêts pour l'étude de l'atrophie musculaire.

Frédéric Derbré , P Bellaud , A Fautrel , Amélie Rébillard

Congrès de l'Association Française d'Histotechnologie, 13-14 juin 2013, Rennes., 2013, Rennes, France

Communication dans un congrès hal-01159364v1

Bénéfices de l'allopurinol dans la prévention de l'atrophie musculaire induite par l'immobilisation

Frédéric Derbré , B Ferrando , V Martinez-Bello , F Sanchis-Gomar , Garcia-Valles R et al.

Congrès P2T, 2010, Grenoble, France

Communication dans un congrès hal-01159493v1

Skeletal muscle regeration during aging and physical exercise : role of oxidative stress and myostatin

Frédéric Derbré , Mari-Carmen Gomez-Cabrera , Ana Nascimiento , Vladimir Martinez-Bello , Fabian Sanchis-Gomar et al.

15th Annual Congress of the European College of Sport Science, 2010, Antalya, Turkey

Communication dans un congrès hal-01159498v1