Frédéric Leroux

142
Documents

Présentation

Frederic Leroux obtained a PhD in chemistry at the University of Konstanz (Germany), under the supervision of Prof. H. Fischer. In 1998, he moved to a postdoctoral position with Prof. M. Schlosser at the University of Lausanne (Switzerland) and accepted the same year a position of Assistant Professor. In 2001 he moved then to the Swiss Federal Institute of Technology in Lausanne (EPFL). He started his independent research career in 2003 as CNRS Research Associate at the University of Strasbourg (France). He obtained his habilitation in 2005 and was promoted CNRS Research Director in 2009.

Frederic Leroux is presently the director of the molecular chemistry department “Laboratoire d’Innovation Moléculaire et Applications” UMR CNRS 7042-LIMA of the Université de Strasbourg, Université de Haute-Alsace and the CNRS (lima.unistra.fr) and director of the joint CNRS-Bayer-Université de Strasbourg laboratory on organofluorine chemistry.

His research (coha.unistra.fr) is published in >120 peer-reviewed publications, 18 patents, 11 books and book chapters and presented by invitation at >80 (inter)national conferences. He is Fellow of the Royal Society of Chemistry (FRSC) and member of the European Academy of Sciences and Arts. He is also a member of the International Scientific Committee of the Moissan Prize (Fluorine Chemistry), Director of the French Fluorine Network (http://www.reseau-fluor.fr) and President of the French-Japanese Society of Medicinal and Fine Chemistry (fjs.crihan.fr).

The philosophy of his research is based on a fruitful interplay of several objectives (a) the synthesis of biologically relevant molecules, (b) asymmetric methodologies using organic and organometallic chemistry, (c) organofluorine chemistry and (d) application of the objectives to industrial problems, which led to strong industrial collaborations. The discovery of new and mild methodologies to introduce fluorine atoms or emergent fluorinated groups (OCF3, CHF2, ...) onto heterocycles as well as their stereoselective introduction onto Csp3-centers is a key topic of his research and developed in close collaboration with industry.

Publications

Publications

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Direct Fluoroformylation of the C3 ‐Position of Indoles with 2,4‐Dinitro(trifluoromethoxy)benzene as Fluorocarbonyl Source

Lilian Wisson , Gilles Hanquet , Fabien Toulgoat , Thierry Billard , Frédéric R Leroux et al.

ChemistryOpen, 2026, 15 (3), pp.e202500563. ⟨10.1002/open.202500563⟩

Article dans une revue hal-05549792v1
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Intertwined Processes in the Pummerer‐Type Rearrangement Affording α‐Trifluoromethoxylated Thioethers and the Corresponding Highly Enantioenriched Sulfoxides

Nicolas Moget , Jérémy Saiter , Fabien Toulgoat , Thierry Billard , Frédéric A Leroux et al.

Chemistry - A European Journal, 2025, 31 (72), pp.e02465. ⟨10.1002/chem.202502465⟩

Article dans une revue hal-05549752v1
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Trifluoromethoxylation of Arynes using 2,4‐Dinitro‐1‐(trifluoromethoxybenzene) as Trifluoromethoxide Anion Source

Lilian Wisson , Gilles Hanquet , Fabien Toulgoat , Thierry Billard , Armen Panossian et al.

European Journal of Organic Chemistry, In press, 27 (28), pp.e202400388. ⟨10.1002/ejoc.202400388⟩

Article dans une revue hal-04591124v1
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Direct Introduction of the 1‐Fluorocyclopropyl Group <i>via</i> Stille Cross‐Coupling – A Way of Getting Around Per‐ and Polyfluoroalkyl Substances (PFASs)

Florian Audet , Morgan Donnard , Armen Panossian , Philipp M Holstein , David Bernier et al.

Advanced Synthesis and Catalysis, 2024, ⟨10.1002/adsc.202400401⟩

Article dans une revue hal-04655162v1
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3‐Amido‐benzo[b]silines: straightforward modular 2‐step synthesis and photophysical properties

Stéphane Golling , Tiahong Yan , Valérie Mazan , Frederic R. Leroux , Ilaria Ciofini et al.

Advanced Synthesis and Catalysis, In press, ⟨10.1002/adsc.202400293⟩

Article dans une revue hal-04538289v1
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Phenylseleno trifluoromethoxylation of alkenes

Clément Delobel , Armen Panossian , Gilles Hanquet , Frédéric R Leroux , Fabien Toulgoat et al.

Beilstein Journal of Organic Chemistry, 2024, 20, pp.2434-2441. ⟨10.3762/bjoc.20.207⟩

Article dans une revue hal-04711420v1
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Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties

Clémence Bonnefoy , Adrien Gallego , Clément Delobel , Betty Raynal , Maxime Decourt et al.

European Journal of Organic Chemistry, 2024, 27 (18), pp.e202400142. ⟨10.1002/ejoc.202400142⟩

Article dans une revue hal-04591439v1
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Synthesis of 2-amidoindenone derivatives through an ynamide carbosilylation / Houben-Hoesch cyclization 2-step sequence

Pierre Hansjacob , Célia Schwoerer , Frédéric R Leroux , Morgan Donnard

Organic & Biomolecular Chemistry, 2024, 22, pp.70-73. ⟨10.1039/D3OB01787G⟩

Article dans une revue hal-04316905v1
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On a seamlessly replicable circular photoreactor for lab-scale continuous flow applications

Yi-Hsuan Tsai , Martin Cattoen , Guillaume Masson , Gabrielle Christen , Lisa Traber et al.

Reaction Chemistry & Engineering, In press, ⟨10.1039/D4RE00109E⟩

Article dans une revue hal-04558234v1
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Synthesis of Polyfluoroalkyl Aryl Ethers Mediated by Sulfuryl Fluoride as a Traceless Activator

Clotilde Plaçais , Lilian Wisson , Isabelle Chataigner , Morgan Donnard , Armen Panossian et al.

Organic Letters, 2024, 26 (46), pp.10046-10050. ⟨10.1021/acs.orglett.4c03989⟩

Article dans une revue hal-04804896v1
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Difluoromethoxylated Ketones as Building Blocks for the Synthesis of Challenging OCF2H‐Bearing N‐Heterocycles.

Anaïs Loison , Gilles Hanquet , Fabien Toulgoat , Thierry Billard , Armen Panossian et al.

European Journal of Organic Chemistry, 2023, 26 (42), pp.e202300695. ⟨10.1002/ejoc.202300695⟩

Article dans une revue hal-04163739v2
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(NHC-olefin)-nickel(0) nanoparticles as catalysts for the (Z)-selective semi-hydrogenation of alkynes and ynamides

Marta G. Avello , Stéphane Golling , Lai Truong-Phuoc , Loic Vidal , Thierry Romero et al.

Chemical Communications, 2023, 59, pp.1537. ⟨10.1039/D2CC05302K⟩

Article dans une revue hal-03909675v2
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Traceless N ‐Polyfluoroalkylation of Weakly Nucleophilic Nitrogen Containing Compounds

Laura Santos , Florian Audet , Morgan Donnard , Armen Panossian , Jean‐pierre Vors et al.

Chemistry - A European Journal, 2023, ⟨10.1002/chem.202300792⟩

Article dans une revue hal-04100627v1
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Ruthenium‐catalyzed Synthesis of Aryl and Alkenyl Halides from Fluorosulfonates

Clotilde Plaçais , Sherif J. Kaldas , Morgan Donnard , Armen Panossian , David Bernier et al.

Chemistry - A European Journal, 2023, ⟨10.1002/chem.202301420⟩

Article dans une revue hal-04100620v1
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Comprehensive Study and Development of a Metal-Free and Mild Nucleophilic Trifluoromethoxylation

Clémence Bonnefoy , Armen Panossian , Gilles Hanquet , Frédéric Leroux , Fabien Toulgoat et al.

Chemistry - A European Journal, 2023, 29 (46), ⟨10.1002/chem.202301513⟩

Article dans une revue hal-04165325v1
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Zinc-Catalyzed Hydrocyanation of Ynamides and Photoisomerization, a General and Selective Access to E and Z Trisubstituted Alpha-Enamidonitriles

Pierre Hansjacob , Frédéric R Leroux , Morgan Donnard

Chemistry - A European Journal, 2023, pp.e202300120. ⟨10.1002/chem.202300120⟩

Article dans une revue hal-04051662v1
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Reactions of substituted arynes and diphenylphosphine oxide or diphenylphosphine-borane complex toward dibenzophospholes – impact of aryne substituents

Marie-Charlotte Belhomme , Thomas Guérin , Armen Panossian , Frédéric R Leroux

Phosphorus, Sulfur, and Silicon and the Related Elements, 2023, 198, ⟨10.1080/10426507.2023.2168270⟩

Article dans une revue hal-04057602v1
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Direct Deprotonative Functionalization of α,α‐Difluoromethyl Ketones using a Catalytic Organosuperbase

Amélia Messara , Armen Panossian , Koichi Mikami , Gilles Hanquet , Frederic Leroux

Angewandte Chemie International Edition, In press, ⟨10.1002/anie.202215899⟩

Article dans une revue hal-03933942v1
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Exploring F/CF3 substituted oxocarbenium ions for the diastereoselective assembly of highly substituted tetrahydrofurans

Anthony J Fernandes , Bastien Michelet , Armen Panossian , Agnès Martin-Mingot , Frédéric R Leroux et al.

Chemical Communications, 2023, 59 (27), pp.4083-4086. ⟨10.1039/d2cc06521e⟩

Article dans une revue hal-04046996v1
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New Chemical Transformations Involving SO 2 F 2 ‐Mediated Alcohol Activation

Florian Audet , Morgan Donnard , Armen Panossian , David Bernier , Sergii Pazenok et al.

Chemical Record, In press, ⟨10.1002/tcr.202300107⟩

Article dans une revue hal-04164625v1
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Direct Access to 2,3-Disubstituted Amido-Indenones through Annulation of 2-Iodobenzaldehydes with Ynamides

Stéphane Golling , Pierre Hansjacob , Nassim Bami , Frédéric R Leroux , Morgan Donnard

Journal of Organic Chemistry, 2022, ⟨10.1021/acs.joc.2c02054⟩

Article dans une revue hal-03883448v1
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Study of Carbamoyl Fluoride: Synthesis, Properties and Applications

Clémence Bonnefoy , Emmanuel Chefdeville , Christian Tourvieille , Armen Panossian , Gilles Hanquet et al.

Chemistry - A European Journal, 2022, 28 (43), ⟨10.1002/chem.202201589⟩

Article dans une revue hal-03744602v1
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Palladium‐Catalyzed Silylcyanation of Ynamides: Regio‐ and Stereoselective Access to Tetrasubstituted 3‐Silyl‐2‐Aminoacrylonitriles

Pierre Hansjacob , Frédéric R. Leroux , Vincent Gandon , Morgan Donnard

Angewandte Chemie International Edition, 2022, ⟨10.1002/anie.202200204⟩

Article dans une revue hal-03541070v1
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One‐step Oxidative Monofluorination of Electron‐deficient Sulfoxides to Access Highly Lewis Acidic Sulfur(VI) Cations

Jordan Berreur , Alberto Diez-Varga , Augustin Manel , Frédéric Leroux , Armen Panossian

Chemistry - A European Journal, 2022, ⟨10.1002/chem.202202564⟩

Article dans une revue hal-03795951v1
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Ketenimines as Intermediates To Access Difluoromethoxylated Scaffolds

Anaïs Loison , Gilles Hanquet , Fabien Toulgoat , Thierry Billard , Armen Panossian et al.

Organic Letters, 2022, ⟨10.1021/acs.orglett.2c03283⟩

Article dans une revue hal-03843401v1
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Synthesis of 3-Amino-5-fluoroalkylfurans by Intramolecular Cyclization

Clotilde Plaçais , Morgan Donnard , Armen Panossian , Jean-Pierre Vors , David Bernier et al.

Organic Letters, 2021, 23 (12), pp.4915-4919. ⟨10.1021/acs.orglett.1c01672⟩

Article dans une revue hal-03325240v1
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Formation of synthetically relevant CF3-substituted phenonium ions in superacid media

Anthony J Fernandes , Bastien Michelet , Armen Panossian , Agnès Martin-Mingot , Frédéric R. Leroux et al.

RSC Advances, 2021, 11 (41), pp.25695 - 25699. ⟨10.1039/d1ra04901a⟩

Article dans une revue hal-03325280v1
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Versatile Access to Tetrasubstituted 2-Amidoacroleins through Formal Silylformylation of Ynamides

Stéphane Golling , Frédéric R. Leroux , Morgan Donnard

Organic Letters, 2021, 23, pp.8093-8097. ⟨10.1021/acs.orglett.1c03141⟩

Article dans une revue hal-03369636v1
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SO2F2-Mediated N-Alkylation of Imino-Thiazolidinones

Laura Santos , Morgan Donnard , Armen Panossian , Jean-Pierre Vors , Peter Jeschke et al.

Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.1c01247⟩

Article dans une revue hal-03325274v1
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Recent synthetic methods towards the –OCHF2 moiety

Anaïs Loison , Fabien Toulgoat , Thierry Billard , Gilles Hanquet , Armen Panossian et al.

Tetrahedron, 2021, 99, pp.132458. ⟨10.1016/j.tet.2021.132458⟩

Article dans une revue hal-03517915v1
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CF3-substituted carbocations: underexploited intermediates with great potential in modern synthetic chemistry

Anthony J Fernandes , Armen Panossian , Bastien Michelet , Agnès Martin-Mingot , Frédéric Leroux et al.

Beilstein Journal of Organic Chemistry, 2021, 17, pp.343-378. ⟨10.3762/bjoc.17.32⟩

Article dans une revue hal-03154651v1
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Electrophilic fluorosulfoxonium cations as hidden Brønsted acid catalysts in (n+2) annulations of strained cycloalkanes

Augustin Manel , Jordan Berreur , Frédéric R. Leroux , Armen Panossian

Organic Chemistry Frontiers, In press, ⟨10.1039/D1QO00840D⟩

Article dans une revue hal-03325336v1
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Direct trifluoromethoxylation without OCF3 ‐carrier via in‐situ generation of fluorophosgene

Jérémy Saiter , Thomas Guérin , Morgan Donnard , Armen Panossian , Gilles Hanquet et al.

European Journal of Organic Chemistry, 2021, 2021 (22), ⟨10.1002/ejoc.202100429⟩

Article dans une revue hal-03228836v1
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The winding road towards an atropo-enantioselective 'ARYNE coupling

David Augros , Corinne Comoy , Yves Fort , Frédéric Leroux , Armen Panossian

European Journal of Organic Chemistry, 2021, ⟨10.1002/ejoc.202100087⟩

Article dans une revue hal-03170152v1
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Study of a Stable “Trifluoromethoxide Anion Solution” Arising from 2,4‐Dinitro‐Trifluoromethoxybenzene

Clémence Bonnefoy , Emmanuel Chefdeville , Armen Panossian , Gilles Hanquet , Frédéric R. Leroux et al.

Chemistry - A European Journal, 2021, 27 (64), pp.15986-15991. ⟨10.1002/chem.202102809⟩

Article dans une revue hal-03582991v1
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Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

Andrej Emanuel Cotman , Thomas Guérin , Ivana Kovačević , Davide Benedetto Tiz , Martina Durcik et al.

ACS Omega, 2021, 6 (14), pp.9723-9730. ⟨10.1021/acsomega.1c00331⟩

Article dans une revue hal-03228819v1
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Aryl Fluoroalkyl Sulfoxides: Optical Stability and p K a Measurement

Amélia Messara , Nicolas Vanthuyne , Patrick Diter , Mourad Elhabiri , Armen Panossian et al.

European Journal of Organic Chemistry, 2021, 2021 (36), ⟨10.1002/ejoc.202100816⟩

Article dans une revue hal-03319682v1
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Deprotonative Functionalization of the Difluoromethyl Group

Laura Santos , Armen Panossian , Morgan Donnard , Jean-Pierre Vors , Sergii Pazenok et al.

Organic Letters, 2020, ⟨10.1021/acs.orglett.0c03380⟩

Article dans une revue hal-02989088v1
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Synthesis and Use of Trifluoromethylthiolated Ketenimines

Frédéric R. Leroux , Thomas Guérin , Nadiia Pikun , Ryutaro Morioka , Armen Panossian et al.

Chemistry - A European Journal, 2020, ⟨10.1002/chem.202002723⟩

Article dans une revue hal-02990038v1
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Transition-Metal-Free Heterobiaryl Synthesis via Aryne Coupling

Tarak Saied , Catherine Demangeat , Armen Panossian , Frédéric Leroux , Yves Fort et al.

European Journal of Organic Chemistry, 2019, 2019 (31-32), pp.5275-5284. ⟨10.1002/ejoc.201900130⟩

Article dans une revue hal-02186792v1
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Efficient asymmetric synthesis of aryl difluoromethyl sulfoxides and their use to access enantiopure α-difluoromethyl alcohols

Chloé Batisse , Maria Cespedes Davila , Marco Castello , Amélia Messara , Bertrand Vivet et al.

Tetrahedron, 2019, 75 (23), pp.3063-3079. ⟨10.1016/j.tet.2019.04.037⟩

Article dans une revue hal-02400108v1

Transition-Metal-Free Approach for the Direct Arylation of Thiophene: Experimental and Theoretical Investigations towards the (Het)-Aryne Route

Catherine Demangeat , Tarak Saied , Romain Ramozzi , Francesca Ingrosso , Manuel Ruiz-Lopez et al.

European Journal of Organic Chemistry, 2019, 2019 (2-3), pp.547-556. ⟨10.1002/ejoc.201801173⟩

Article dans une revue hal-02186820v1
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Access towards enantiopure α,α-difluoromethyl alcohols by means of sulfoxides as traceless chiral auxiliaries

Chloé Batisse , Armen Panossian , Gilles Hanquet , Frédéric Leroux

Chemical Communications, 2018, 54 (74), pp.10423-10426. ⟨10.1039/C8CC05571H⟩

Article dans une revue hal-02150060v1

A physico-chemical investigation of fluorine-enriched quinolines

Fallia Aribi , Armen Panossian , Denis Jacquemin , Jean-Pierre Vors , Sergii Pazenok et al.

New Journal of Chemistry, 2018, 42 (12), pp.10036-10047. ⟨10.1039/c8nj00916c⟩

Article dans une revue hal-02105499v1

New synthetic access to 3-fluoroalkyl-5-pyrazolecarboxylates and carboxylic acids

Alberto Gomez Herrera , Etienne Schmitt , Armen Panossian , Jean-Pierre Vors , Sergiy Pazenok et al.

Journal of Fluorine Chemistry, 2018, 214, pp.17-23. ⟨10.1016/j.jfluchem.2018.07.010⟩

Article dans une revue hal-02105504v1

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

Timothée Naret , Jérôme Bignon , Guillaume Bernadat , Mohamed Benchekroun , Helene Levaique et al.

European Journal of Medicinal Chemistry, 2018, 143, pp.473-490. ⟨10.1016/j.ejmech.2017.11.055⟩

Article dans une revue hal-02105508v1

Stereoselectivity Switch in the Trapping of Polar Organometallics with Andersen’s Reagent—Access to Highly Stereoenriched Transformable Biphenyls

Julien Bortoluzzi , Vishwajeet Jha , Guillaume Levitre , Mickaël Fer , Jordan Berreur et al.

Journal of Organic Chemistry, 2018, 83 (15), pp.7751-7761. ⟨10.1021/acs.joc.8b00648⟩

Article dans une revue hal-02105503v1

Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites

Chelliah Selvam , Isabelle Lemasson , Isabelle Brabet , Nadia Oueslati , Berin Karaman et al.

Journal of Medicinal Chemistry, 2018, 61 (5), pp.1969-1989. ⟨10.1021/acs.jmedchem.7b01438⟩

Article dans une revue hal-02018007v1
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Synthesis of Mono- and Bis(fluoroalkyl)pyrimidines from FARs, Fluorinated Acetoacetates, and Malononitrile Provides Easy Access to Novel High-Value Pyrimidine Scaffolds

E. Schmitt , B. Commare , A. Panossian , J.-P. Vors , S. Pazenok et al.

Chemistry - A European Journal, 2018, 24 (6), pp.1311-1316. ⟨10.1002/chem.201703982⟩

Article dans une revue hal-02105509v1
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2,4-Bis(fluoroalkyl)quinoline-3-carboxylates as Tools for the Development of Potential Agrochemical Ingredients

Fallia Aribi , Armen Panossian , Jean-Pierre Vors , Sergiy Pazenok , Frédéric R. Leroux

European Journal of Organic Chemistry, 2018, Organofluorine Chemistry in Europe, 2018 (27-28), pp.3792-3802. ⟨10.1002/ejoc.201800375⟩

Article dans une revue hal-02105501v1

Towards biphenyl based frustrated Lewis pairs

Julien Bortoluzzi , Frédéric Leroux , Armen Panossian

Abstracts of Papers of the American Chemical Society, 2018, 256

Article dans une revue hal-04889950v1

Asymmetric α-Sulfonyl- and α-Phosphoryl-Oxylation of Ketones by a Chiral Hypervalent Iodine(III)

Guillaume Levitre , Audrey Dumoulin , Pascal Retailleau , Armen Panossian , Frederic R. Leroux et al.

Journal of Organic Chemistry, 2017, 82 (22), pp.11877-11883. ⟨10.1021/acs.joc.7b01597⟩

Article dans une revue hal-02105318v1
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Transition-Metal-Free Synthesis of a Known Intermediate in the Formal Synthesis of (-)-Steganacin

David Augros , Boubacar Yalcouye , Sabine Choppin , Matthieu Chessé , Armen Panossian et al.

European Journal of Organic Chemistry, 2017, 2017 (3), pp.497-503. ⟨10.1002/ejoc.201601239⟩

Article dans une revue hal-02105793v1
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Control of axial chirality in absence of transition metals based on arynes

Frédéric R. Leroux , Armen Panossian , David Augros

Comptes Rendus. Chimie, 2017, 20 (6), pp.682-692. ⟨10.1016/j.crci.2016.12.001⟩

Article dans une revue hal-02105315v1
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Fluoroalkyl Amino Reagents for the Introduction of the Fluoro(trifluoromethoxy)methyl Group onto Arenes and Heterocycles

Etienne Schmitt , Sebastien Bouvet , Bruce Pegot , Armen Panossian , Jean-Pierre Vors et al.

Organic Letters, 2017, 19 (18), pp.4960-4963. ⟨10.1021/acs.orglett.7b02444⟩

Article dans une revue hal-02105321v1

Switchable Diastereoselectivity in the Fluoride-Promoted Vinylogous Mukaiyama–Michael Reaction of 2-[(Trimethylsilyl)oxy]furan Catalyzed by Crown Ethers

Giorgio Della Sala , Marina Sicignano , Rosaria Schettini , Francesco de Riccardis , Luigi Cavallo et al.

Journal of Organic Chemistry, 2017, 82 (13), pp.6629-6637. ⟨10.1021/acs.joc.7b00743⟩

Article dans une revue hal-02105791v1

Le fluor, un élément qui vous veut du bien

Frédéric Leroux

L'Actualité Chimique, 2017, 421

Article dans une revue hal-05020031v1
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Fluoroalkyl Amino Reagents (FARs): A General Approach towards the Synthesis of Heterocyclic Compounds Bearing Emergent Fluorinated Substituents

Bruno Commare , Etienne Schmitt , Fallia Aribi , Armen Panossian , Jean-Pierre Vors et al.

Molecules, 2017, 22 (6), pp.977. ⟨10.3390/molecules22060977⟩

Article dans une revue hal-02105792v1
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Tri- and difluoromethoxylated N-based heterocycles − Synthesis and insecticidal activity of novel F3CO- and F2HCO-analogues of Imidacloprid and Thiacloprid

Grégory Landelle , Etienne Schmitt , Armen Panossian , Jean-Pierre Vors , Sergiy Pazenok et al.

Journal of Fluorine Chemistry, 2017, 203, pp.155-165. ⟨10.1016/j.jfluchem.2017.08.006⟩

Article dans une revue hal-02105310v1

The French Connection : Editorial

Frédéric R. Leroux

CHIMIA, 2016, 70 (1-2), pp.6-7

Article dans une revue hal-04876344v1

When Chirality Meets “Buchwald-Type” Phosphines: Synthesis and Evaluation in Frustrated Lewis Pair-, Lewis Base- and Palladium-Promoted Asymmetric Catalysis

Frédéric R. Leroux , Mickaël Fer , Joséphine Cinqualbre , Julien Bortoluzzi , Matthieu Chessé et al.

European Journal of Organic Chemistry, 2016, 2016 (26), pp.4545-4553. ⟨10.1002/ejoc.201600727⟩

Article dans une revue istex hal-03004119v1
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A Major Advance in the Synthesis of Fluoroalkyl Pyrazoles: Tuneable Regioselectivity and Broad Substitution Patterns

Etienne Schmitt , Armen Panossian , Jean-Pierre Vors , Christian Funke , Norbert Lui et al.

Chemistry - A European Journal, 2016, 22 (32), pp.11239-11244. ⟨10.1002/chem.201601621⟩

Article dans une revue hal-03004108v1

Access to Atropisomerically Enriched Biaryls by the Coupling of Aryllithiums with Arynes under Control by Homochiral Oxazolines

Boubacar Yalcouye , Anaïs Brehier , David Augros , Armen Panossian , Sabine Choppin et al.

European Journal of Organic Chemistry, 2016, 2016 (4), pp.725-732. ⟨10.1002/ejoc.201501503⟩

Article dans une revue istex hal-02304102v1

Atropo-diastereoselective coupling of aryllithiums and arynes — variations around the chiral auxiliary

Frédéric R. Leroux , David Augros , Boubacar Yalcouye , Anaïs Berthelot-Bréhier , Matthieu Chessé et al.

Tetrahedron, 2016, 72 (34), pp.5208-5220. ⟨10.1016/j.tet.2016.01.047⟩

Article dans une revue istex hal-03004140v1
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A new approach toward the synthesis of 2,4-bis(fluoroalkyl)-substituted quinoline derivatives using fluoroalkyl amino reagent chemistry

Fallia Aribi , Etienne Schmitt , Armen Panossian , Jean-Pierre Vors , Sergiy Pazenok et al.

Organic Chemistry Frontiers, 2016, 3 (11), pp.1392-1415. ⟨10.1039/C6QO00319B⟩

Article dans une revue hal-03004130v1

Lithium/Element Exchange as an Efficient Tool for Accessing Atropo-enriched Biaryls <i>via</i> Arynes

Armen Panossian , Frédéric Leroux

CHIMIA, 2016, 70 (1), pp.43-47. ⟨10.2533/chimia.2016.43⟩

Article dans une revue hal-03004175v1

A General Approach towards NH-Pyrazoles That Bear Diverse Fluoroalkyl Groups by Means of Fluorinated Iminium Salts

Étienne Schmitt , Gregory Landelle , Jean-Pierre Vors , Norbert Lui , Sergiy Pazenok et al.

European Journal of Organic Chemistry, 2015, 27, pp.6052-6060. ⟨10.1002/ejoc.201500920⟩

Article dans une revue istex hal-02305226v1

Atroposelective synthesis of axially chiral P,S-ligands based on arynes

Anais Berthelot-Brehier , Armen Panossian , Francoise Colobert-Leuenberger , Frédéric Leroux

Organic Chemistry Frontiers, 2015, 2 (6), pp.634-644. ⟨10.1039/C5QO00067J⟩

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Determination of the absolute configuration of phosphinic analogues of glutamate

Bruno Commare , Delphine Rigault , Isabelle Lemasson , Patrick Deschamps , Alain Tomas et al.

Organic & Biomolecular Chemistry, 2015, 13 (4), pp.1106-1112. ⟨10.1039/C4OB01960A⟩

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In Situ Generated Fluorinated Iminium Salts for Difluoromethylation and Difluoroacetylation

Frédéric R. Leroux , Etienne Schmitt , Baptiste Rugeri , Armen Panossian , Jean-Pierre Vors et al.

Organic Letters, 2015, 17 (18), pp.4510-4513. ⟨10.1021/acs.orglett.5b02184⟩

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Modular Synthesis of Biaryl-Substituted Phosphine Ligands: Application in Microwave-Assisted Palladium-Catalyzed C-N Cross-Coupling Reactions

Chandani Singh , Jayant Rathod , Vishwajeet Jha , Armen Panossian , Pradeep Kumar et al.

European Journal of Organic Chemistry, 2015, 2015 (29), pp.6515-6525. ⟨10.1002/ejoc.201500962⟩

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Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

Joanna Wencel‐delord , Armen Panossian , Frédéric Leroux , Françoise Colobert

Chemical Society Reviews, In press, ⟨10.1039/c5cs00012b⟩

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Substituent effects on the relative rates and free energies of ortho-lithiation reactions: families of fluorobenzenes as the substrates

F Mongin , C Curty , E Marzi , Frédéric Leroux , M Schlosser

ARKIVOC - Online Journal of Organic Chemistry, 2015, 4, pp.48-65. ⟨10.3998/ark.5550190.p008.926⟩

Article dans une revue hal-02304104v1

Unusual phosphine oxidation: new triazolopyridyl-quinolyl phosphine oxide fluorescent dyes

R. Ballesteros-Garrido , B. Abarca , R. Ballesteros , F. Colobert , Frédéric R. Leroux et al.

RSC Advances, 2015, 5 (38), pp.29809-29813. ⟨10.1039/C5RA04386G⟩

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Synthesis and biological evaluation of new nucleosides derived from trifluoromethoxy-4-quinolones

Kristína Plevová , Katarína Briestenská , Francoise Colobert-Leuenberger , Jela Mistríková , Viktor Milata et al.

Tetrahedron Letters, 2015, 56 (36), pp.5112-5115. ⟨10.1016/j.tetlet.2015.07.031⟩

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Multi-nuclear NMR of axially chiral biaryls in polypeptide orienting solvents: spectral discriminations and enantiorecognition mechanisms

Philippe Berdagué , Jose-Enrique Herbert-Pucheta , Vishwajeet Jha , Armen Panossian , Frédéric Leroux et al.

New Journal of Chemistry, 2015, 39 (12), pp.9504-9517. ⟨10.1039/c5nj01434d⟩

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Asymmetric Bromine-Lithium Exchange: Application toward the Synthesis of New Biaryl-Diphosphine Ligands

Frédéric R. Leroux , Julien Graff , Elżbieta Łastawiecka , Laure Guénée , Frédéric Leroux et al.

Advanced Synthesis and Catalysis, 2015, 357 (13), pp.2833-2839. ⟨10.1002/adsc.201500323⟩

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Tribute to Prof. Manfred Schlosser (1934-2013) Obituary

Renzo Ruzziconi , Frédéric Leroux

Journal of Fluorine Chemistry, 2015, 171, pp.2-3. ⟨10.1016/j.jfluchem.2014.09.014⟩

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A New Synthesis and Process Development of Bis(fluoroalkyl)pyrazoles As Novel Agrophores

F Giornal , G Landelle , N Lui , J Vors , S Pazenok et al.

Organic Process Research and Development, 2014, 18 (8), pp.1002-1009. ⟨10.1021/Op500102h⟩

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Novel C1-symmetric dibenzophosphole ligands: application in hydroformylation reactions

Abdelouahd Oukhrib , Laurence Bonnafoux , Armen Panossian , Sandrine Waifang , Duc Hanh Nguyen et al.

Tetrahedron, 2014, 70 (7), pp.1431-1436. ⟨10.1016/j.tet.2014.01.003⟩

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Fluorine Chemistry Special Feature

Frédéric Leroux , Mark Ford , Sergiy Pazenok

Organic Process Research and Development, 2014, 18 (8), ⟨10.1021/op500216s⟩

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Trifluoromethyl Ethers and -Thioethers as Tools for Medicinal Chemistry and Drug Discovery

Gregory Landelle , Armen Panossian , Frédéric Leroux

Current Topics in Medicinal Chemistry, 2014, 14 (7), pp.941-951

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A theoretical and experimental study of the racemization process of hexaaza[5]helicenes

Belen Abarca , Rafael Ballesteros , Rosa Adam , Rafael Ballesteros-Garrido , Frédéric Leroux et al.

Tetrahedron, 2014, 70 (45), pp.8750-8757. ⟨10.1016/j.tet.2014.09.018⟩

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A concise atroposelective formal synthesis of (-)-steganone

Boubacar Yalcouye , Sabine Choppin , Armen Panossian , Frédéric Leroux , Francoise Colobert-Leuenberger

European Journal of Organic Chemistry, 2014, 2014 (28), pp.6285-6294. ⟨10.1002/ejoc.201402761⟩

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Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients

Florence Giornal , Lars Rodefeld , Norbert Lui , Jean-Pierre Vors , Frédéric Leroux

Journal of Fluorine Chemistry, 2013, 152, pp.2-11. ⟨10.1016/j.jfluchem.2012.11.008⟩

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Convenient and Reliable Routes Towards 2-Aminothiazoles: Palladium-Catalyzed versus Copper-Catalyzed Aminations of Halothiazoles

Stéphanie Toulot , Timo Heinrich , Frédéric Leroux

Advanced Synthesis and Catalysis, 2013, 355 (16), pp.3263-3272. ⟨10.1002/adsc.201300591⟩

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Recent advances in transition metal-catalyzed Csp(2)-monofluoro-, difluoro-, perfluoromethylation and trifluoromethylthiolation

Gregory Landelle , Armen Panossian , Sergiy Pazenok , Jean-Pierre Vors , Frédéric Leroux

Beilstein Journal of Organic Chemistry, 2013, 9, pp.2476-2536. ⟨10.3762/bjoc.9.287⟩

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Manfred Schlosser (1934-2013) Obituary

Frédéric Leroux

Angewandte Chemie International Edition, 2013, 52 (48), ⟨10.1002/anie.201308231⟩

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Synthesis and structural properties of hexaaza[5]helicene containing two [1,2,3]triazolo[1,5-a]pyridine moieties

Rosa Adam , Rafael Ballesteros-Garrido , Oriol Vallcorba , Belen Abarca , Rafael Ballesteros et al.

Tetrahedron Letters, 2013, 54 (32), pp.4316-4319. ⟨10.1016/j.tetlet.2013.06.014⟩

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A New Life for an Old Reagent: Fluoroalkyl Amino Reagents as Efficient Tools for the Synthesis of Diversely Fluorinated Pyrazoles

Sergiy Pazenok , Florence Giornal , Grégory Landelle , Norbert Lui , Jean-Pierre Vors et al.

European Journal of Organic Chemistry, 2013, 2013 (20), pp.4249-4253. ⟨10.1002/ejoc.201300561⟩

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Palladium-Catalyzed Intramolecular Direct Arylation of 2-Bromo-diaryl Sulfoxides via C-H Bond Activation

Thomas Wesch , Anaïs Brehier , Frédéric Leroux , Francoise Colobert-Leuenberger

Organic Letters, 2013, 15 (10), pp.2490-2493. ⟨10.1021/ol400966q⟩

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Atropodiastereoselective C-H Olefination of Biphenyl p-Tolyl Sulfoxides with Acrylates

Thomas Wesch , Frédéric Leroux , Francoise Colobert-Leuenberger

Advanced Synthesis and Catalysis, 2013, 355 (11-12), pp.2139-2144. ⟨10.1002/adsc.201300446⟩

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Transition-Metal-Free Atropo-Selective Synthesis of Biaryl Compounds Based on Arynes

Frédéric Leroux , Anaïs Brehier , Laurence Bonnafoux , Armen Panossian , Francoise Colobert-Leuenberger

Chemistry - A European Journal, 2012, 18 (45), pp.14232-14236. ⟨10.1002/chem.201202739⟩

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Stereoselective Synthesis of P-Chirogenic Dibenzophosphole-Boranes via Aryne Intermediates

Vincent Diemer , Anaïs Brehier , Jérôme Bayardon , Sylvain Juge , Frédéric Leroux et al.

Journal of Organic Chemistry, 2012, 77 (14), pp.6117-6127. ⟨10.1021/jo3009098⟩

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Construction of the biaryl-part of vancomycin aglycon via atropo-diastereoselective Suzuki-Miyaura coupling

Timo Leermann , Pierre-Emmanuel Broutin , Frédéric Leroux , Francoise Colobert-Leuenberger

Organic & Biomolecular Chemistry, 2012, 10 (20), pp.4095-4102. ⟨10.1039/c2ob25373a⟩

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Stereoselective Synthesis of o -Bromo (or Iodo)aryl P-Chirogenic Phosphines Based on Aryne Chemistry

Frédéric R. Leroux , Jérôme Bayardon , Hugo Laureano , Vincent Diemer , Mathieu Dutartre et al.

Journal of Organic Chemistry, 2012, 77 (13), pp.5759-5769. ⟨10.1021/jo300910w⟩

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Aryne-mediated fluorination: Synthesis of fluorinated biaryls via a sequential desilylation-halide elimination-fluoride addition process

Vincent Diemer , Juan Garcia , Frédéric Leroux , Francoise Colobert-Leuenberger

Journal of Fluorine Chemistry, 2012, 134, pp.146-155. ⟨10.1016/j.jfluchem.2011.02.017⟩

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Triazolopyridines. Part 28. The ring-chain isomerization strategy: triazolopyridine- and triazoloquinoline-pyridine based fluorescence ligands

Rafael Ballesteros-Garrido , Estefania Delgado-Pinar , Belen Abarca , Rafael Ballesteros , Frédéric Leroux et al.

Tetrahedron, 2012, 68 (19), pp.3701-3707. ⟨10.1016/j.tet.2012.03.029⟩

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Bromine-lithium exchange: An efficient tool in the modular construction of biaryl ligands

Laurence Bonnafoux , Frédéric Leroux , Francoise Colobert-Leuenberger

Beilstein Journal of Organic Chemistry, 2011, 7, pp.1278-1287. ⟨10.3762/bjoc.7.148⟩

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Highly Efficient One-Pot Access to Functionalized Arylboronic Acids via Noncryogenic Bromine/Magnesium Exchanges

Timo Leermann , Frédéric Leroux , Francoise Colobert-Leuenberger

Organic Letters, 2011, 13 (17), pp.4479-4481. ⟨10.1021/ol2016252⟩

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Efficient and Complementary Methods Offering Access to Synthetically Valuable 1,2-Dibromobenzenes

Vincent Diemer , Frédéric Leroux , Francoise Colobert-Leuenberger

European Journal of Organic Chemistry, 2011, 2, pp.327-340. ⟨10.1002/ejoc.201001217⟩

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Catalytic Palladium Phosphination: Modular Synthesis of C1-Symmetric Biaryl-Based Diphosphines

Laurence Bonnafoux , Rafael Gramage-Doria , Francoise Colobert , Frederic R. Leroux

Chemistry - A European Journal, 2011, 17 (39), pp.11008-11016. ⟨10.1002/chem.201101529⟩

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Polar Organometallic Chemistry

Frédéric Leroux

Current Organic Chemistry, 2011, 15 (13)

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Through-Space J(P,P) and J(P,F) Spin-Spin Coupling in C-1-Symmetric Biaryl Diphosphanes

Laurence Bonnafoux , Ludger Ernst , Frédéric Leroux , Francoise Colobert-Leuenberger

European Journal of Inorganic Chemistry, 2011, 22, pp.3387-3397. ⟨10.1002/ejic.201100428⟩

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Regioselectivity in the Aryne Cross-Coupling of Aryllithiums with Functionalized 1,2-Dibromobenzenes

Vincent Diemer , Manon Begaud , Frédéric Leroux , Francoise Colobert-Leuenberger

European Journal of Organic Chemistry, 2011, 2, pp.341-354. ⟨10.1002/ejoc.201001283⟩

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[1,2,3]Triazolo[1,5-a]pyridyl phosphines reflecting the influence of phosphorus lone pair orientation on spectroscopic properties

Rafael Ballesteros-Garrido , Laurence Bonnafoux , Fernando Blanco , Rafael Ballesteros , Frédéric Leroux et al.

Dalton Transactions, 2011, 40 (6), pp.1387-1395. ⟨10.1039/C0DT01183E⟩

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A General Approach to (Trifluoromethoxy)pyridines: First X-ray Structure Determinations and Quantum Chemistry Studies

Baptiste Manteau , Pierre Genix , Lydia Brelot , Jean-Pierre Vors , Sergiy Pazenok et al.

European Journal of Organic Chemistry, 2010, 2010 (31), pp.6043-6066. ⟨10.1002/ejoc.201000958⟩

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2,2′,6-Tribromobiphenyl via Transition-Metal-Free ARYNE Coupling: A Valuable Tool in the Synthesis of Biphenyls

Frédéric R. Leroux , Laurence Bonnafoux , Françoise Colobert

SYNLETT, 2010, 2010 (19), pp.2953-2955. ⟨10.1055/s-0030-1259025⟩

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New trends in the chemistry of α-fluorinated ethers, thioethers, amines and phosphines

Baptiste Manteau , Sergiy Pazenok , Jean-Pierre Vors , Frédéric Leroux

Journal of Fluorine Chemistry, 2010, 131 (2), pp.140-158. ⟨10.1016/j.jfluchem.2009.09.009⟩

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Efficient synthesis of quaternary and P-stereogenic phosphonium triflates

Emmanuelle Remond , Arnaud Tessier , Frédéric Leroux , Jérome Bayardon , Sylvain Jugé

Organic Letters, 2010, 12 (7), pp.1568-1571. ⟨10.1021/ol100304c⟩

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Axial Chirality Control During Suzuki−Miyaura Cross-Coupling Reactions: The tert -Butylsulfinyl Group as an Efficient Chiral Auxiliary

Françoise Colobert , Victoria Valdivia , Sabine Choppin , Frédéric Leroux , Inmaculada Fernández et al.

Organic Letters, 2009, 11 (22), pp.5130-5133. ⟨10.1021/ol9020755⟩

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The deprotonative metalation of [1,2,3]triazolo[1,5-a]quinoline. Synthesis of 8-haloquinolin-2-carboxaldehydes

Rafael Ballesteros-Garrido , Frédéric Leroux , Rafael Ballesteros , Belén Abarca , Françoise Colobert

Tetrahedron, 2009, 65 (22), pp.4410-4417. ⟨10.1016/j.tet.2009.03.058⟩

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The [1,2,3]Triazolo[1,5-a]pyridine ring: A sensitive sensor for the electronic profile of phosphorus substituents

Rafael Ballesteros-Garrido , Laurence Bonnafoux , Frédéric Leroux , Belén Abarca , Françoise Colobert

Dalton Transactions, 2009, 26, pp.5068. ⟨10.1039/b906034k⟩

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3‐(Pyridin‐2‐yl)[1,2,3]triazolo[1,5‐ a ]quinoline: A Theoretical and Experimental Analysis of Ring‐Chain Isomerisation

Rafael Ballesteros-Garrido , Fernando Blanco , Rafael Ballesteros , Frédéric Leroux , Belén Abarca et al.

European Journal of Organic Chemistry, 2009, 2009 (33), pp.5765-5778. ⟨10.1002/ejoc.200900818⟩

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[1,2,3]Triazolo[1,5-a]pyridine derivatives as molecular chemosensors for zinc(ii), nitrite and cyanide anions

Rafael Ballesteros-Garrido , Belén Abarca , Rafael Ballesteros , Carmen Ramírez de Arellano , Frédéric Leroux et al.

New Journal of Chemistry, 2009, 33 (10), pp.2102. ⟨10.1039/b906992e⟩

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Triazolopyridines. Part 26: The preparation of novel [1,2,3]triazolo[1,5-a]pyridine sulfoxides

Belén Abarca , Rafael Ballesteros , Rafael Ballesteros-Garrido , Françoise Colobert , Frédéric Leroux

Tetrahedron, 2008, 64 (17), pp.3794-3801. ⟨10.1016/j.tet.2008.02.011⟩

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Trifluoromethyl ethers – synthesis and properties of an unusual substituent

Frédéric Leroux , Baptiste Manteau , Jean-Pierre Vors , Sergiy Pazenok

Beilstein Journal of Organic Chemistry, 2008, 4, ⟨10.3762/bjoc.4.13⟩

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Inhibitors of Steroidal Cytochrome P450 Enzymes as Targets for Drug Development

Eckhard Baston , Frederic Leroux

Recent Patents on Anti-Cancer Drug Discovery, 2007, 2 (1), pp.31-58. ⟨10.2174/157489207779561453⟩

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α-Fluorinated Ethers as “Exotic” Entity in Medicinal Chemistry

Peter Jeschke , Eckhard Baston , Frederic Leroux

Mini-Reviews in Medicinal Chemistry, 2007, 7 (10), pp.1027-1034. ⟨10.2174/138955707782110150⟩

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A Practical Transition Metal‐Free Aryl‐Aryl Coupling Method: Arynes as Key Intermediates

Frédéric R. Leroux , Laurence Bonnafoux , Christophe Heiss , Françoise Colobert , Don Antoine Lanfranchi

Advanced Synthesis and Catalysis, 2007, 349 (17-18), pp.2705-2713. ⟨10.1002/adsc.200700211⟩

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Efficient palladium catalyzed synthesis of heteroaromatic sulfoxides

Françoise Colobert , Rafael Ballesteros-Garrido , Frédéric Leroux , Rafael Ballesteros , Belén Abarca

Tetrahedron Letters, 2007, 48 (39), pp.6896-6899. ⟨10.1016/j.tetlet.2007.07.165⟩

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First Modular Synthesis of Dissymmetric Biaryldiphosphine Ligands Allowing Tunable Steric and Electronic Effects

Frédéric R. Leroux , Hanspeter Mettler

Advanced Synthesis and Catalysis, 2007, 349 (3), pp.323-336. ⟨10.1002/adsc.200600300⟩

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The first stereoselective Pd-catalyzed addition of boronic acids onto aldehydes

Alexandra Novodomskà , Mària Dudičovà , Frédéric Leroux , Françoise Colobert

Tetrahedron: Asymmetry, 2007, 18 (13), pp.1628-1634. ⟨10.1016/j.tetasy.2007.06.031⟩

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Relative carbanion basicities as driving force for an intramolecular silyl migration of lithiated biphenyls

Laurence Bonnafoux , Rosario Scopelliti , Frédéric Leroux , Françoise Colobert

Tetrahedron Letters, 2007, 48 (49), pp.8768-8772. ⟨10.1016/j.tetlet.2007.10.004⟩

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Triazolopyridines. Part 25: Synthesis of new chiral ligands from [1,2,3]triazolo[1,5-a]pyridines

Belén Abarca , Rafael Ballesteros , Rafael Ballesteros-Garrido , Françoise Colobert , Frédéric Leroux

Tetrahedron, 2007, 63 (42), pp.10479-10485. ⟨10.1016/j.tet.2007.07.101⟩

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New Vistas in Halogen/Metal Exchange Reactions: The Discrimination Between Seemingly Equal Halogens

Laurence Bonnafoux , Nathalie Nicod , Frederic Leroux , Berengere Quissac , Francoise Colobert

Letters in Organic Chemistry, 2006, 3 (2), pp.165-169. ⟨10.2174/157017806775224279⟩

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A Highly Efficient Low Temperature Modification of the Classical Ullmann Reaction

Frederic Leroux , Roger Simon , Nathalie Nicod

Letters in Organic Chemistry, 2006, 3 (12), pp.948-954. ⟨10.2174/157017806779467979⟩

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Ligand Tailoring: The First Modular Assembly of Atropisomeric Biarylbisphosphine Ligands

Frédéric Leroux , Hanspeter Mettler

SYNLETT, 2006, 5, pp.0766-0770. ⟨10.1055/s-2006-933107⟩

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The Effect of Ring Size on Reactivity: The Diagnostic Value of ‘Rate Profiles’

Eric Masson , Frédéric Leroux

Helvetica Chimica Acta, 2005, 88 (6), pp.1375-1386. ⟨10.1002/hlca.200590110⟩

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Palladium-Catalyzed Borylation of Phenyl Bromides and Application in One-Pot Suzuki−Miyaura Biphenyl Synthesis

Pierre-Emmanuel Broutin , Igor Čerňa , Maria Campaniello , Frédéric Leroux , Françoise Colobert

Organic Letters, 2004, 6 (24), pp.4419-4422. ⟨10.1021/ol048303b⟩

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N-(4-biphenylmethyl)imidazoles as potential therapeutics for the treatment of prostate cancer

Frédéric Leroux , T Hutschenreuter , C Charriere , R Scopelliti , R Hartmann

Helvetica Chimica Acta, 2003, 86 (7), pp.2671-2686. ⟨10.1002/hlca.200390217⟩

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Access to heterocycles bearing emergent fluorinated substituents - as FAR as possible!

Etienne Schmitt , Fallia Aribi , Armen Panossian , Jean-Pierre Vors , Sergiy Pazenoek et al.

253rd American Chemical Society National Meeting & Exposition, April 2-6, 2017, San Francisco, Apr 2017, San Francisco, United States

Communication dans un congrès hal-04876291v1

Carbamoyl fluorides: from synthesis to radiochemistry

Clémence Bonnefoy , Emmanuel Chefdeville , Armen Panossian , Gilles Hanquet , Frédéric R. Leroux et al.

57th International Conference on Medicinal Chemistry, Jul 2023, Lille, France

Poster de conférence hal-04720307v1

Carbamoyl Fluorides: From Synthesis to Radiochemistry

Clémence Bonnefoy , Emmanuel Chefdeville , Armen Panossian , Gilles Hanquet , Frédéric R. Leroux et al.

28th French-Japanese Symposium on Medicinal & Fine Chemistry, Oct 2023, Nice, France

Poster de conférence hal-04720313v1

Carbamoyl fluoride as a potential new tag for fluorine-18 labeling

Clémence Bonnefoy , Christian Tourvieille , Armen Panossian , Gilles Hanquet , Frédéric R. Leroux et al.

24th International Symposium on Radiopharmaceutical Sciences, May 2022, Nantes, France

Poster de conférence hal-04720303v1

2,4-Dinitro-trifluoromethoxybenzene: a promising reagent in fluorine chemistry

Clémence Bonnefoy , Emmanuel Chefdeville , Christian Tourvielle , Armen Panossian , Gilles Hanquet et al.

55th Bürgenstock Conference, May 2022, Brunnen, Switzerland

Poster de conférence hal-04720299v1

Enantioselective Catalysis by Nonmetal Frustrated Lewis Pairs

Armen Panossian , Julien Bortoluzzi , Frédéric Leroux

Topics in Enantioselective Catalysis, 09, WORLD SCIENTIFIC, pp.123-159, 2022, Series on Chemistry, Energy and the Environment, ⟨10.1142/9789811248436_0005⟩

Chapitre d'ouvrage hal-04171426v1

Modern Fluorine‐Containing Agrochemicals

Sergii Pazenok , David Bernier , Morgan Donnard , Gilles Hanquet , Armen Panossian et al.

Z. Rappoport. PATAI'S Chemistry of Functional Groups, 1, Wiley; Wiley, 2022, 9780470682531. ⟨10.1002/9780470682531.pat1013⟩

Chapitre d'ouvrage hal-03920395v1

Modern Fluorine-Containing Agrochemicals

Sergii Pazenok , Frédéric Leroux

Frontiers of Organofluorine Chemistry, WORLD SCIENTIFIC (EUROPE), pp.695-732, 2020, ⟨10.1142/9781786347336_0016⟩

Chapitre d'ouvrage hal-03940952v1

Rapport de Conjoncture du CoNRS 2014 (INC / Section 12)

Chantal Andraud , Philippe Belmont , J.M. Campagne , Gaëlle Chouraqui , Emmanuel Gras et al.

CNRS Editions, Paris,. Rapport de Conjoncture du CoNRS 2014, CNRS Editions, Paris,, pp.255-274, 2014, 978-2-271-08746-1

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