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Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA
Christophe Delehedde
,
Ivan Ciganek
,
Pierre Louis Bernard
,
Nabila Laroui
,
Cathy Costa da Silva
et al.
Article dans une revue
hal-04772634
v1
|
|
Targeting BTN2A1 enhances Vγ9Vδ2 T-cell effector functions and triggers tumor cell pyroptosis
Anne-Charlotte Le Floch
,
Caroline Imbert
,
Nicolas Boucherit
,
Laurent Gorvel
,
Stéphane Fattori
et al.
Article dans une revue
hal-04735873
v1
|
|
DOK1 and DOK2 regulate CD8 T cell signaling and memory formation without affecting tumor cell killing
Vladimir Laletin
,
Pierre-Louis Bernard
,
Camille Montersino
,
Yuji Yamanashi
,
Daniel Olive
et al.
Article dans une revue
hal-04772643
v1
|
|
Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA
Christophe Delehedde
,
Ivan Ciganek
,
Pierre Louis Bernard
,
Nabila Laroui
,
Cathy Costa da Silva
et al.
Article dans une revue
hal-04735549
v1
|
|
DOK1 and DOK2 regulate CD8 T cell signaling and memory formation without affecting tumor cell killing
Vladimir Laletin
,
Pierre-Louis Bernard
,
Camille Montersino
,
Yuji Y. Yamamoto
,
Daniel Olive
et al.
Article dans une revue
hal-04654761
v1
|
|
Production of CRISPRi-engineered primary human mammary epithelial cells with baboon envelope pseudotyped lentiviral vectors
Sonia Pastor
,
Julien Wicinski
,
Emmanuelle Charafe-Jauffret
,
Els Verhoeyen
,
Geoffrey Guittard
et al.
Article dans une revue
hal-04772645
v1
|
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Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors
Clémence Demerlé
,
Laurent Gorvel
,
Marielle Mello
,
Sonia Pastor
,
Clara Degos
et al.
Article dans une revue
hal-04114937
v1
|
|
Production of CRISPRi-engineered primary human mammary epithelial cells with baboon envelope pseudotyped lentiviral vectors
Sonia Pastor
,
Julien Wicinski
,
Emmanuelle Charafe-Jauffret
,
Els Verhoeyen
,
Geoffrey Guittard
et al.
Article dans une revue
hal-04735885
v1
|
|
Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets
Vladimir Laletin
,
Pierre-Louis Bernard
,
Cathy Costa da Silva
,
Geoffrey Guittard
,
Jacques Nunes
Article dans une revue
(article de synthèse)
hal-04114285
v1
|
|
XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
Laia Richart
,
Mary-Loup Picod-Chedotel
,
Michel Wassef
,
Manon Macario
,
Setareh Aflaki
et al.
Article dans une revue
hal-03951681
v1
|
|
TET2 regulates immune tolerance in chronically activated mast cells
Riccardo Rigo
,
Rabie Chelbi
,
Julie Agopian
,
Sebastien Letard
,
Aurélien Griffon
et al.
Article dans une revue
hal-04772652
v1
|
|
Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity
Pierre-Louis Bernard
,
Rebecca Delconte
,
Sonia Pastor
,
Vladimir Laletin
,
Cathy Costa da Silva
et al.
Article dans une revue
hal-04772651
v1
|
|
CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression
Laurys Boudin
,
Alexandre de Nonneville
,
Pascal Finetti
,
Geoffrey Guittard
,
Jacques Nunes
et al.
Article dans une revue
hal-03765362
v1
|
|
Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity
Pierre-Louis Bernard
,
Rebecca Delconte
,
Sonia Pastor
,
Vladimir Laletin
,
Cathy Costa da Silva
et al.
Article dans une revue
hal-03773961
v1
|
|
CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression
Laurys Boudin
,
Alexandre de Nonneville
,
Pascal Finetti
,
Geoffrey Guittard
,
Jacques Nunes
et al.
Article dans une revue
hal-04772648
v1
|
|
NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS
Rebecca Delconte
,
Geoffrey Guittard
,
Wilford Goh
,
Soroor Hediyeh-Zadeh
,
Robert Hennessy
et al.
Article dans une revue
hal-04772658
v1
|
|
Une piste en immunothérapie du cancer
Pierre-Louis Bernard
,
Vladimir Laletin
,
Sonia Pastor
,
Jacques Nunès
,
Geoffrey Guittard
Article dans une revue
inserm-03152135
v1
|
|
NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS
Rebecca B. Delconte
,
Geoffrey Guittard
,
Wilford Goh
,
Soroor Hediyeh-Zadeh
,
Robert J. Hennessy
et al.
Article dans une revue
hal-02533541
v1
|
|
Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer
Esma Karkeni
,
Stephanie Morin
,
Berna Bou Tayeh
,
Armelle Goubard
,
Emmanuelle Josselin
et al.
Article dans une revue
hal-02528933
v1
|
|
Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer
Esma Karkeni
,
Stéphanie Morin
,
Berna Bou Tayeh
,
Armelle Goubard
,
Emmanuelle Josselin
et al.
Article dans une revue
hal-04772659
v1
|
|
TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling
Bochra Zidi
,
Christelle Vincent-Fabert
,
Laurent Pouyet
,
Marion Seillier
,
Amelle Vandevelde
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (1), pp.211-216. ⟨10.1073/pnas.1809980116⟩
Article dans une revue
hal-02145737
v1
|
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A Prime-Pull-Amplify Vaccination Strategy To Maximize Induction of Circulating and Genital-Resident Intraepithelial CD8+ Memory T Cells
Nicolas Çuburu
,
Rina Kim
,
Geoffrey Guittard
,
Cynthia Thompson
,
Patricia Day
et al.
Article dans une revue
hal-04772662
v1
|
|
Evolutionary and expression analyses reveal a pattern of ancient duplications and functional specializations in the diversification of the Downstream of Kinase (DOK) genes
Geoffrey Guittard
,
Pierre Pontarotti
,
Samuel Granjeaud
,
Magda Rodrigues
,
Laurent Abi-Rached
et al.
Article dans une revue
inserm-02148721
v1
|
|
TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling
Bochra Zidi
,
Christelle Vincent-Fabert
,
Laurent Pouyet
,
Marion Seillier
,
Amelle Vandevelde
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 116 (1), pp.211-216. ⟨10.1073/pnas.1809980116⟩
Article dans une revue
hal-04772663
v1
|
|
Evolutionary and expression analyses reveal a pattern of ancient duplications and functional specializations in the diversification of the Downstream of Kinase (DOK) genes
Geoffrey Guittard
,
Pierre Pontarotti
,
Samuel Granjeaud
,
Magda Rodrigues
,
Laurent Abi-Rached
et al.
Article dans une revue
hal-04772664
v1
|
|
The Cish SH2 domain is essential for PLC-gamma 1 regulation in TCR stimulated CD8(+) T cells
Geoffrey Guittard
,
Ana Dios-Esponera
,
Douglas C. Palmer
,
Itoro Akpan
,
Valarie A. Barr
et al.
Article dans une revue
hal-02143617
v1
|
|
The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells
Geoffrey Guittard
,
Ana Dios-Esponera
,
Douglas Palmer
,
Itoro Akpan
,
Valarie Barr
et al.
Article dans une revue
hal-04772666
v1
|
|
Unexpected Cartilage Phenotype in CD4-Cre-Conditional SOS-Deficient Mice
Geoffrey Guittard
,
Devorah Gallardo
,
Wenmei Li
,
Nicolas Melis
,
Julian Lui
et al.
Article dans une revue
hal-04772669
v1
|
|
Ionic immune suppression within the tumour microenvironment limits T cell effector function
Robert Eil
,
Suman Vodnala
,
David Clever
,
Christopher Klebanoff
,
Madhusudhanan Sukumar
et al.
Article dans une revue
hal-04772670
v1
|
|
Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance
Douglas Palmer
,
Geoffrey Guittard
,
Zulmarie Franco
,
Joseph Crompton
,
Robert Eil
et al.
Article dans une revue
hal-04772671
v1
|
|
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules
A Rodriguez-Peña
,
J Gomez-Rodriguez
,
R Kortum
,
D Palmer
,
Z Yu
et al.
Article dans une revue
hal-04772673
v1
|
|
Absence of both Sos‐1 and Sos‐2 in peripheral CD4 + T cells leads to PI3K pathway activation and defects in migration
Geoffrey Guittard
,
Robert Kortum
,
Lakshmi Balagopalan
,
Nicolas Çuburu
,
Phan Nguyen
et al.
Article dans une revue
hal-04772674
v1
|
|
An Emerging Role for PI5P in T Cell Biology.
Jacques A. Nunès
,
Geoffrey Guittard
Article dans une revue
inserm-00828688
v1
|
|
An Emerging Role for PI5P in T Cell Biology
Jacques Nunès
,
Geoffrey Guittard
Article dans une revue
hal-04772676
v1
|
|
B7-DC-Ig Enhances Vaccine Effect by a Novel Mechanism Dependent on PD-1 Expression Level on T Cell Subsets
Mikayel Mkrtichyan
,
Yana Najjar
,
Estella Raulfs
,
Linda Liu
,
Solomon Langerman
et al.
Article dans une revue
hal-04772677
v1
|
|
Evidence for a positive role of PtdIns5P in T‐cell signal transduction pathways
Geoffrey Guittard
,
Eva Mortier
,
Hélène Tronchère
,
Guylène Firaguay
,
Audrey Gérard
et al.
Article dans une revue
hal-04772679
v1
|
|
Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.
Geoffrey Guittard
,
Eva Mortier
,
Hélène Tronchère
,
Guylène Firaguay
,
Audrey Gérard
et al.
Article dans une revue
inserm-00474713
v1
|
|
Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.
Geoffrey Guittard
,
Audrey Gérard
,
Sophie Dupuis-Coronas
,
Hélène Tronchère
,
Eva Mortier
et al.
Article dans une revue
inserm-00364224
v1
|
|
Dok-4 Is a Novel Negative Regulator of T Cell Activation
Audrey Gérard
,
Marguerite Ghiotto
,
Camille Fos
,
Geoffrey Guittard
,
Daniel Compagno
et al.
Article dans une revue
hal-04772680
v1
|
|
Dok-4 is a novel negative regulator of T cell activation.
Audrey Gérard
,
Marguerite Ghiotto
,
Camille Fos
,
Geoffrey Guittard
,
Daniel Compagno
et al.
Article dans une revue
inserm-00374930
v1
|
|
Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells
Geoffrey Guittard
,
Audrey Gérard
,
Sophie Dupuis-Coronas
,
Hélène Tronchère
,
Eva Mortier
et al.
Article dans une revue
hal-04772682
v1
|