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Evaluation of dual-function molecules containing both Zn-Ionophore and aggregation inhibition moieties for mutant p53 protein reactivation
Kalvin Kwan
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Ashkan Saffari
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Lauryn Grcic
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Alfredo Acosta
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Grace Leech
et al.
Article dans une revue
inserm-05314293v1
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Protoporphyrin IX-Derived Ruthenium(II) Complexes for Photodynamic Therapy in Gastric Cancer Cells
Andrés Restrepo-Acevedo
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María Isabel Murillo
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Christophe Orvain
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Chloé Thibaudeau
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Sevda Recberlik
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Article dans une revue
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Platinum(ii) and ruthenium(ii) coordination complexes equipped with an anchoring site for binding the protein kinase enzyme pockets: synthesis, molecular docking and biological assays
Matthieu Scarpi-Luttenauer
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Katia Galentino
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Christophe Orvain
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Marco Cecchini
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Article dans une revue
inserm-05210825v1
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Inverse Correlation between Endoplasmic Reticulum Stress Intensity and Antitumor Immune Response with Ruthenium(II)-Based Photosensitizers for the Photodynamic Therapy of Head and Neck Squamous Cell Carcinoma
Chloé Thibaudeau
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Cyril Bour
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Matthieu Scarpi-Luttenauer
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Pierre Mesdom
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Johannes Karges
et al.
Article dans une revue
hal-05374218v1
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The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms
Gilles Riegel
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Sevda Recberlik
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Marie-Elodie Spaety
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Gernot Poschet
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Article dans une revue
hal-04721006v1
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Multifunctional metallochaperone modifications for targeting subsite cavities in mutant p53-Y220C
Jessica J Miller
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Kalvin Kwan
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Anaïs Blanchet
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Christophe Orvain
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Georg Mellitzer
et al.
Article dans une revue
hal-04295261v1
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A novel ΔNp63-dependent immune mechanism improves prognosis of HPV-related head and neck cancer
Jana Mourtada
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Christelle Lony
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Anaïs Nicol
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Justine de Azevedo
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Cyril Bour
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Article dans une revue
hal-04440322v1
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Synthesis of Cytotoxic Iron-Containing Macrocycles Through Unexpected C(sp2) C(sp2) Bonds Formation
Carolina Torres‐gutiérrez
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Aldo S Estrada‐montaño
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Christophe Orvain
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Georg Mellitzer
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Christian Gaiddon
et al.
Article dans une revue
hal-05595590v1
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Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target?
Amandine Badie
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Christian Gaiddon
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Georg Mellitzer
Article dans une revue
inserm-05281008v1
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The EXTREME Regimen Associating Cetuximab and Cisplatin Favors Head and Neck Cancer Cell Death and Immunogenicity with the Induction of an Anti-Cancer Immune Response
Justine de Azevedo
,
Jana Mourtada
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Cyril Bour
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Veronique Devignot
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Philippe Schultz
et al.
Article dans une revue
hal-04889946v1
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Morpho-functional analysis of patient-derived xenografts reveals differential impact of gastric cancer and chemotherapy on the tumor ecosystem, affecting immune check point, metabolism, and sarcopenia
A. Venkatasamy
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E. Guerin
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W. Reichardt
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V. Devignot
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M P Chenard
et al.
Article dans une revue
hal-04295287v1
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Isoforms of the p53 Family and Gastric Cancer: A Ménage à Trois for an Unfinished Affair
Anais Blanchet
,
Agathe Bourgmayer
,
Jean-Emmanuel Kurtz
,
Georg Mellitzer
,
Christian Gaiddon
Article dans une revue
hal-03451009v1
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Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of Gastric Cancer
Aina Venkatasamy
,
Eric Guerin
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Anais Blanchet
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Christophe Orvain
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Véronique Devignot
et al.
Article dans une revue
hal-03450657v1
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Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer
Christian Gaiddon
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Isabelle Gross
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Xiangjun Meng
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Marjorie Sidhoum
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Georg Mellitzer
et al.
Article dans une revue
hal-03450715v1
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The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms
Marine Beck
,
Mathilde Baranger
,
Ahlam Moufok-Sadoun
,
Emilie Bersuder
,
Isabelle Hinkel
et al.
Article dans une revue
hal-03044463v1
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Anticancer activity of ruthenium and osmium cyclometalated compounds: identification of ABCB1 and EGFR as resistance mechanisms
Cynthia Licona
,
Jean-Baptiste Delhorme
,
Gilles Riegel
,
Vania Vidimar
,
Ricardo Cerón-Camacho
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Article dans une revue
hal-03013615v1
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A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53
Vania Vidimar
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Cynthia Licona
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Ricardo Cerón-Camacho
,
Eric Guérin
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Pierre Coliat
et al.
Article dans une revue
inserm-02363227v1
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HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway
Marie-Elodie Spaety
,
Alexandre Gries
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Amandine Badie
,
Aina Venkatasamy
,
Benoît Romain
et al.
Article dans une revue
inserm-02363213v1
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A ruthenium anticancer compound interacts with histones and impacts differently on epigenetic and death pathways compared to cisplatin
Cynthia Licona
,
Marie-Élodie Spaety
,
Antonella Capuozzo
,
Moussa Ali
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Rita Santamaria
et al.
Article dans une revue
hal-01483834v1
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Structural tuning of organoruthenium compounds allows oxidative switch to control ER stress pathways and bypass multidrug resistance
Mun Juinn Chow
,
Cynthia Licona
,
Giorgia Pastorin
,
Georg Mellitzer
,
Wee Han Ang
et al.
Article dans une revue
inserm-02365338v1
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Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63
Yannick von Grabowiecki
,
Paula Abreu
,
Orphee Blanchard
,
Lavinia Palamiuc
,
Samir Benosman
et al.
Article dans une revue
inserm-02365332v1
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Subcellular Localization and Transport Kinetics of Ruthenium Organometallic Anticancer Compounds in Living Cells: A Dose-Dependent Role for Amino Acid and Iron Transporters
M Klajner
,
Cynthia Licona
,
L Fetzer
,
Pascal Hébraud
,
Georg Mellitzer
et al.
Article dans une revue
hal-04684613v1
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Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity
Neal Anthwal
,
Michelle Pelling
,
Suzanne Claxton
,
Georg Mellitzer
,
Caitlin Collin
et al.
Article dans une revue
hal-04006946v1
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Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity
Vania Vidimar
,
Xiangjun Meng
,
Marcelina Klajner
,
Cynthia Licona
,
Ludivine Fetzer
et al.
Article dans une revue
istex
hal-04654755v1
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Enteroendocrine cells and lipid absorption
Georges Mellitzer
,
Gerard Gradwohl
Article dans une revue
hal-04692450v1
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Complex Regulation of p73 Isoforms after Alteration of Amyloid Precursor Polypeptide (APP) Function and DNA Damage in Neurons
S Benosman
,
X Meng
,
Y von Grabowiecki
,
L Palamiuc
,
L Hritcu
et al.
Article dans une revue
hal-05259710v1
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Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium
François Gerbe
,
Johan van Es
,
Leila Makrini
,
Bénédicte Brulin
,
Georg Mellitzer
et al.
Article dans une revue
hal-02459483v1
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Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival
Georg Mellitzer
,
Anthony Beucher
,
Viviane Lobstein
,
Pascal Michel
,
Sylvie Robine
et al.
Article dans une revue
hal-04004280v1
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Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development
Josselin Soyer
,
Lydie Flasse
,
Wolfgang Raffelsberger
,
Anthony Beucher
,
Christophe Orvain
et al.
Article dans une revue
hal-04088194v1
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GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist
Nayeem Quayum
,
Alecksandr Kutchma
,
Suparna A. Sarkar
,
Kirstine Juhl
,
Gerard Gradwohl
et al.
Article dans une revue
hal-04118007v1
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IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas
Georg Mellitzer
,
Stefan Bonné
,
Reini Luco
,
Mark van de Casteele
,
Nathalie Lenne-Samuel
et al.
Article dans une revue
hal-04104930v1
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Genetic determinants of pancreatic epsilon-cell development.
R Scott Heller
,
Marjorie Jenny
,
Patrick Collombat
,
Ahmed Mansouri
,
Catherine Tomasetto
et al.
Article dans une revue
istex
hal-00187550v1
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Pancreatic Islet Progenitor Cells in Neurogenin 3-Yellow Fluorescent Protein Knock-Add-On Mice
Georg Mellitzer
,
Mercè Martín
,
Marjorie Sidhoum-Jenny
,
Christophe Orvain
,
Jochen Barths
et al.
Article dans une revue
hal-04130831v1
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Spatial and temporal ‘knock down’ of gene expression by electroporation of double-stranded RNA and morpholinos into early postimplantation mouse embryos
Georg Mellitzer
,
Marc Hallonet
,
Lan Chen
,
Siew-Lan Ang
Article dans une revue
hal-04154926v1
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Control of cell behaviour by signalling through Eph receptors and ephrins
Georg Mellitzer
,
Qiling Xu
,
David Wilkinson
Article dans une revue
istex
inserm-05281124v1
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Roles of Eph receptors and ephrins in segmental patterning
Qiling Xu
,
Georg Mellitzer
,
David Wilkinson
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (1934–1990), 2000, 355 (1399), pp.993-1002. ⟨10.1098/rstb.2000.0635⟩
Article dans une revue
inserm-05281123v1
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Eph receptors and ephrins restrict cell intermingling and communication
Georg Mellitzer
,
Qiling Xu
,
David Wilkinson
Article dans une revue
inserm-05281126v1
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In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins
Qiling Xu
,
Georg Mellitzer
,
Vicky Robinson
,
David Wilkinson
Article dans une revue
inserm-05281147v1
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STAT5 Involvement in the Differentiation Response of Primary Chicken Myeloid Progenitor Cells to Chicken Myelomonocytic Growth Factor
Irina Woldman
,
Georg Mellitzer
,
Matthias Kieslinger
,
Dieter Buchhart
,
Andreas Meinke
et al.
Journal of immunotherapy : official journal of the Society for Biological Therapy, 1997, 159 (2), pp.877-886
Article dans une revue
inserm-05281177v1
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Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation
Georg Mellitzer
,
Oliver Wessely
,
Thomas Deckert
,
Andreas Meinket
,
Michael J Haymant
et al.
Proceedings of the National Academy of Sciences of the United States of America, 1996, 93(18):9600-5 (18), pp.9600-9605. ⟨10.1073/pnas.93.18.9600⟩
Article dans une revue
inserm-05281197v1
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