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Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B-Cell Lymphoma
Gildas Bertho
,
Leonardo Lordello
,
Xi Chen
,
Covadonga Lucas-Torres
,
Imed Eddine Oumezziane
Article dans une revue
hal-03648893v1
|
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Structural analysis of unstable norbixin isomers guided by pure shift nuclear magnetic resonance
Gildas Bertho
,
Imed Eddine Oumezziane
,
Cédric Caradeuc
,
Louis Guibout
,
Christine Balducci
Article dans une revue
hal-03648920v1
|
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Synthesis and characterization of novel conformers of ( E ) ‐ 2‐(3‐nitro‐ H ‐imidazo[1,2‐ a ]pyridin‐2‐ylthio)‐ N ′‐benzylideneacetohydrazide derivatives
Evrard Ablo
,
Souleymane Coulibaly
,
Siomenan Coulibali
,
Kouassi Signo
,
Patrick‐armand Achi
Article dans une revue
hal-03812767v1
|
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The complex metabolism of poststerone in male rats
Christine Balducci
,
Laurence Dinan
,
Louis Guibout
,
Anne-Sophie Foucault
,
Christel Carbonne
Article dans une revue
hal-03684677v1
|
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Adenomyosis is associated with specific proton nuclear magnetic resonance (1H-NMR) serum metabolic profiles
Mathilde Bourdon
,
Pietro Santulli
,
Fatiha Kateb
,
Khaled Pocate-Cheriet
,
Frederic Batteux
Article dans une revue
hal-03684698v1
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On the Supra‐LUMO Interaction: Case Study of a Sudden Change of Electronic Structure as a Functional Emergence
Alexis Gosset
,
Štěpánka Nováková Lachmanová
,
Sawsen Cherraben
,
Gildas Bertho
,
Jérémy Forté
Article dans une revue
hal-03684619v1
|
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Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases
Hélène Arnould
,
Vincent Baudouin
,
Anne Baudry
,
Luiz Ribeiro
,
Hector Ardila-Osorio
Article dans une revue
hal-03413478v1
|
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Distinction between 2′- and 3′-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration
Raoul Manuel
,
Michelle de Souza Lima
,
Sébastien Dilly
,
Sylvain Daunay
,
Patricia Abbe
Article dans une revue
hal-03990867v1
|
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Distinction between 2′- and 3′-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration
Raoul Manuel
,
Michelle de Souza Lima
,
Sébastien Dilly
,
Sylvain Daunay
,
Patricia Abbe
Article dans une revue
hal-03248720v1
|
|
The follicular fluid metabolome differs according to the endometriosis phenotype
Khaled Pocate-Cheriet
,
Pietro Santulli
,
Fatiha Kateb
,
Mathilde Bourdon
,
Chloé Maignien
Article dans une revue
hal-03493619v1
|
|
Endometriosis phenotypes are associated with specific serum metabolic profiles determined by proton-nuclear magnetic resonance
Chloé Maignien
,
Pietro Santulli
,
Fatiha Kateb
,
Cédric Caradeuc
,
Louis Marcellin
Article dans une revue
hal-03492022v1
|
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Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment
Baptiste Fohlen
,
Quentin Tavernier
,
Thi-Mum Huynh
,
Cédric Caradeuc
,
Delphine Le Corre
Article dans une revue
hal-03684748v1
|
|
Urinary metabolic profiling of asymptomatic acute intermittent porphyria using a rule-mining-based algorithm
Margaux Luck
,
Caroline Schmitt
,
Neila Talbi
,
Laurent Gouya
,
Cédric Caradeuc
Article dans une revue
hal-03684742v1
|
|
Model of the Interaction between the NF-κB Inhibitory Protein p100 and the E3 Ubiquitin Ligase β-TrCP based on NMR and Docking Experiments
Maxime Melikian
,
Baptiste Eluard
,
Gildas Bertho
,
Véronique Baud
,
Nathalie Evrard-Todeschi
Article dans une revue
hal-03684765v1
|
|
Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice
Céline Desseille
,
Séverine Deforges
,
Olivier Biondi
,
Léo Houdebine
,
Domenico D’amico
Article dans une revue
hal-03684756v1
|
|
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
Manal Sarkis
,
Maria Miteva
,
Maria Chiara Dasso Lang
,
Maryse Jaouen
,
Marie-Agnès Sari
Article dans une revue
hal-03684762v1
|
|
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
Manal Sarkis
,
Maria Miteva
,
Maria Chiara Dasso Lang
,
Maryse Jaouen
,
Marie-Agnès Sari
Article dans une revue
hal-03689998v1
|
|
Interaction of a small molecule Natura-α and STAT3-SH2 domain to block Y705 phosphorylation and inhibit lupus nephritis
J.W. Chiao
,
Maxime Melikian
,
Liying Han
,
Chengsen Xue
,
Allen Tsao
Article dans une revue
hal-03684776v1
|
|
Rule-Mining for the Early Prediction of Chronic Kidney Disease Based on Metabolomics and Multi-Source Data
Margaux Luck
,
Gildas Bertho
,
Mathilde Bateson
,
Alexandre Karras
,
Anastasia Yartseva
Article dans une revue
hal-03684770v1
|
|
Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.
Lionel Ducassou
,
Gabriella Jonasson
,
Laura Dhers
,
Nicolas Pietrancosta
,
Booma Ramassamy
Article dans une revue
hal-01449701v1
|
|
The urinary metabolome of chronic kidney disease
Nicolas Pallet
,
Eric Thervet
,
Philippe Beaune
,
Alexandre Karras
,
Gildas Bertho
Article dans une revue
hal-03684819v1
|
|
Novel RANK Antagonists for the Treatment of Bone-Resorptive Disease: Theoretical Predictions and Experimental Validation
Stéphane Téletchéa
,
Verena Stresing
,
Soizic Hervouet
,
Marc Baud'Huin
,
Marie-Françoise Heymann
Article dans une revue
inserm-01644748v1
|
|
Urinary Metabolic Fingerprint of Acute Intermittent Porphyria Analyzed by 1 H NMR Spectroscopy
Mickael Carichon
,
Nicolas Pallet
,
Caroline Schmitt
,
Thibaud Lefebvre
,
Laurent Gouya
Article dans une revue
hal-03684829v1
|
|
A new derivative detected in accelerated ageing of artesunate-amodiaquine fixed dose combination tablets
Cedric Charrier
,
Gildas Bertho
,
Olivier Petigny
,
Philippe Moneton
,
Robert Azerad
Article dans une revue
hal-03684836v1
|
|
Thiolactone Sulfoxides as New Reactive Metabolites Acting as Bis-Electrophiles: Implication in Clopidogrel and Prasugrel Bioactivation
Patrick Dansette
,
Dan Levent
,
Assia Hessani
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-03684856v1
|
|
Toward Stable Electron Paramagnetic Resonance Oximetry Probes: Synthesis, Characterization, and Metabolic Evaluation of New Ester Derivatives of a Tris-( para -carboxyltetrathiaaryl)methyl (TAM) Radical
Christophe Decroos
,
Véronique Balland
,
Jean-Luc Boucher
,
Gildas Bertho
,
Yun Xu-Li
Article dans une revue
hal-03684842v1
|
|
Naphthalene-dioxygenase catalysed cis-dihydroxylation of bicyclic azaarenes
Claude Chopard
,
Gildas Bertho
,
Thierry Prangé
Article dans une revue
hal-03684941v1
|
|
Tryptophan Depletion and the Kinase GCN2 Mediate IFN-γ–Induced Autophagy
Sophie Fougeray
,
Iadh Mami
,
Gildas Bertho
,
Philippe Beaune
,
Eric Thervet
Article dans une revue
hal-03684891v1
|
|
Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer
Patrick Dansette
,
Julien Rosi
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-03684944v1
|
|
Metabolic Activation of Prasugrel: Nature of the Two Competitive Pathways Resulting in the Opening of Its Thiophene Ring
Patrick Dansette
,
Julien Rosi
,
Justine Debernardi
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-03684932v1
|
|
Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis
Patricia Rada
,
Ana Rojo
,
Nathalie Evrard-Todeschi
,
Nadia Innamorato
,
Axelle Cotte
Article dans une revue
hal-03684929v1
|
|
Contact-based ligand-clustering approach for the identification of active compounds in virtual screening
Gildas Bertho
,
Alexey Mantsyzov
,
Guillaume Bouvier
,
Nathalie Evrard-Todeschi
Article dans une revue
hal-03684866v1
|
|
Paraoxonase-1 and clopidogrel efficacy
Patrick Dansette
,
Julien Rosi
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-03684957v1
|
|
Automatic clustering of docking poses in virtual screening process using self-organizing map
Guillaume Bouvier
,
Nathalie Evrard-Todeschi
,
Jean-Pierre Girault
,
Gildas Bertho
Article dans une revue
hal-03684971v1
|
|
Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel
Patrick Dansette
,
Stéphanie Thébault
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-03684983v1
|
|
Oxidative and Reductive Metabolism of Tris( p -carboxyltetrathiaaryl)methyl Radicals by Liver Microsomes
Christophe Decroos
,
Yun Li
,
Gildas Bertho
,
Yves Frapart
,
Daniel Mansuy
Article dans une revue
hal-03684990v1
|
|
Synthetic studies towards diazepanone scaffolds
Christophe Decroos
,
Yun Li
,
Gildas Bertho
,
Yves Frapart
,
Daniel Mansuy
Article dans une revue
hal-03685013v1
|
|
Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel
Patrick Dansette
,
Julie Libraire
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-03684993v1
|
|
Oxidation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes: evidence for their oxidative decarboxylation and molecular origin of their specific ability to react with O2˙−
Christophe Decroos
,
Yun Li
,
Gildas Bertho
,
Yves Frapart
,
Daniel Mansuy
Article dans une revue
hal-02102841v1
|
|
The key-role of tyrosine 155 in the mechanism of prion transconformation as highlighted by a study of sheep mutant peptides
Gildas Bertho
,
Guillaume Bouvier
,
Gaston Hui Bon Hoa
,
Jean-Pierre Girault
Article dans une revue
hal-03685032v1
|
|
Transfer-NMR and Docking Studies Identify the Binding of the Peptide Derived from Activating Transcription Factor 4 to Protein Ubiquitin Ligase β-TrCP. Competition STD-NMR with β-Catenin
Julien Pons
,
Nathalie Evrard-Todeschi
,
Gildas Bertho
,
Josyane Gharbi-Benarous
,
Valérie Tanchou
Article dans une revue
hal-03685028v1
|
|
Diastereoselective Additions to (3S)-3-Aminodehydrocaprolactams: Development of a Versatile Synthesis of New Substituted CyclicL-Lysines
Camille Levraud
,
Sandrine Calvet-Vitale
,
Gildas Bertho
,
Hamid Dhimane
Article dans une revue
hal-03685043v1
|
|
Structure of the Complex between Phosphorylated Substrates and the SCF β-TrCP Ubiquitin Ligase Receptor: A Combined NMR, Molecular Modeling, and Docking Approach
Nathalie Evrard-Todeschi
,
Julien Pons
,
Josyane Gharbi-Benarous
,
Gildas Bertho
,
Richard Benarous
Article dans une revue
hal-03685021v1
|
|
Efficient synthesis of polyfunctionalised enantiopure diazepanone scaffolds
Olivier Monasson
,
Maryon Ginisty
,
Gildas Bertho
,
Christine Gravier-Pelletier
,
Yves Le Merrer
Article dans une revue
hal-03685046v1
|
|
STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody.
Simon Megy
,
Gildas Bertho
,
Josyane Gharbi-Benarous
,
Françoise Baleux
,
Richard Benarous
Article dans une revue
pasteur-00166653v1
|
|
Allosteric tuning of the intra-cavity binding properties of a calix[6]arene through external binding to a Zn(II) center coordinated to amino arms
Ulrich Darbost
,
Olivier Sénèque
,
Yun Li
,
Gildas Bertho
,
Jerome Marrot
Article dans une revue
hal-00391396v1
|
|
First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives
Patrick M. Dansette
,
Gildas Bertho
,
Daniel Mansuy
Article dans une revue
hal-00068627v1
|
|
Solution structure of a peptide derived from the oncogenic protein beta-Catenin in its phosphorylated and nonphosphorylated states.
Simon Megy
,
Gildas Bertho
,
Josyane Gharbi-Benarous
,
Françoise Baleux
,
Richard Benarous
Article dans une revue
pasteur-00166821v1
|
|
Possible role of region 152-156 in structural duality of a peptide fragment from sheep prion protein
Simon Megy
,
Gildas Bertho
,
Serguey A. Kozin
,
Marie Pascale M. P. Debey
,
Gaston Hui Bon Hoa
Protein Science, 2004, 13 (12), pp.3151-3160
Article dans une revue
hal-02677622v1
|