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            Characterization of POP mixture redistribution and identification of their molecular signature in xenografted fat mice
        
                            
                                                                                                            Théo Jamay
                                                                ,
                                                                                                                                Philippe Noirez
                                                                ,
                                                                                                                                Haidar Djemai
                                                                ,
                                                                                                                                Layale Youssef
                                                                ,
                                                                                                                                Justine Massias
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05079695
                                            v1
                                    
            
        
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    | 
        
                            
                    
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            Metabolic Heterogeneity in Diffuse Large B-Cell Lymphoma Cells Reveals an Innovative Antimetabolic Combination Strategy
        
                            
                                                                                                            Leonardo Lordello
                                                                ,
                                                                                                                                Stéphanie Nuan-Aliman
                                                                ,
                                                                                                                                Karoline Kielbassa-Elkadi
                                                                ,
                                                                                                                                Aurélie Montagne
                                                                ,
                                                                                                                                Konstantina Kotta
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                             (data paper)
                    
        
        
            
                
                    hal-05053122
                                            v1
                                    
            
        
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    | 
        
                            
                    
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            Phytochemical Study of the Anthelminthic Potential of Guadeloupean Plant Biodiversity
        
                            
                                                                                                            Tressy Cabald
                                                                ,
                                                                                                                                Carine Marie-Magdeleine
                                                                ,
                                                                                                                                Lucien Philibert
                                                                ,
                                                                                                                                Cédric Caradeuc
                                                                ,
                                                                                                                                Gildas Bertho
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04670316
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
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            The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus
        
                            
                                                                                                            Elias Abi Akar
                                                                ,
                                                                                                                                Laure Weill
                                                                ,
                                                                                                                                Mirella El Khoury
                                                                ,
                                                                                                                                Cédric Caradeuc
                                                                ,
                                                                                                                                Gildas Bertho
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05316643
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
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            Revisiting the nature and pharmacodynamics of tacrolimus metabolites
        
                            
                                                                                                            Rudy Mevizou
                                                                ,
                                                                                                                                Hassan Aouad
                                                                ,
                                                                                                                                François-Ludovic Sauvage
                                                                ,
                                                                                                                                Hélène Arnion
                                                                ,
                                                                                                                                Emilie Pinault
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05291791
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            One touch is all it takes: the supramolecular interaction between ubiquitin and lanthanide complexes revisited by paramagnetic NMR and molecular dynamics
        
                            
                                                                                                            Karen dos Santos
                                                                ,
                                                                                                                                Alessio Bartocci
                                                                ,
                                                                                                                                Natacha Gillet
                                                                ,
                                                                                                                                Sandrine Denis-Quanquin
                                                                ,
                                                                                                                                Amandine Roux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04609190
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
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            Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B-Cell Lymphoma
        
                            
                                                                                                            Gildas Bertho
                                                                ,
                                                                                                                                Leonardo Lordello
                                                                ,
                                                                                                                                Xi Chen
                                                                ,
                                                                                                                                Covadonga Lucas-Torres
                                                                ,
                                                                                                                                Imed Eddine Oumezziane
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03648893
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Synthesis and characterization of novel conformers of ( E ) ‐ 2‐(3‐nitro‐ H ‐imidazo[1,2‐ a ]pyridin‐2‐ylthio)‐ N ′‐benzylideneacetohydrazide derivatives
        
                            
                                                                                                            Evrard Ablo
                                                                ,
                                                                                                                                Souleymane Coulibaly
                                                                ,
                                                                                                                                Siomenan Coulibali
                                                                ,
                                                                                                                                Kouassi Signo
                                                                ,
                                                                                                                                Patrick‐armand Achi
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03812767
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
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            Structural analysis of unstable norbixin isomers guided by pure shift nuclear magnetic resonance
        
                            
                                                                                                            Gildas Bertho
                                                                ,
                                                                                                                                Imed Eddine Oumezziane
                                                                ,
                                                                                                                                Cédric Caradeuc
                                                                ,
                                                                                                                                Louis Guibout
                                                                ,
                                                                                                                                Christine Balducci
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03648920
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
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            On the Supra‐LUMO Interaction: Case Study of a Sudden Change of Electronic Structure as a Functional Emergence
        
                            
                                                                                                            Alexis Gosset
                                                                ,
                                                                                                                                Štěpánka Nováková Lachmanová
                                                                ,
                                                                                                                                Sawsen Cherraben
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Jérémy Forté
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684619
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The complex metabolism of poststerone in male rats
        
                            
                                                                                                            Christine Balducci
                                                                ,
                                                                                                                                Laurence Dinan
                                                                ,
                                                                                                                                Louis Guibout
                                                                ,
                                                                                                                                Anne-Sophie Foucault
                                                                ,
                                                                                                                                Christel Carbonne
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684677
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Distinction between 2′- and 3′-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration
        
                            
                                                                                                            Raoul Manuel
                                                                ,
                                                                                                                                Michelle de Souza Lima
                                                                ,
                                                                                                                                Sébastien Dilly
                                                                ,
                                                                                                                                Sylvain Daunay
                                                                ,
                                                                                                                                Patricia Abbe
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03248720
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Distinction between 2′- and 3′-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration
        
                            
                                                                                                            Raoul Manuel
                                                                ,
                                                                                                                                Michelle de Souza Lima
                                                                ,
                                                                                                                                Sébastien Dilly
                                                                ,
                                                                                                                                Sylvain Daunay
                                                                ,
                                                                                                                                Patricia Abbe
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03990867
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
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            Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases
        
                            
                                                                                                            Hélène Arnould
                                                                ,
                                                                                                                                Vincent Baudouin
                                                                ,
                                                                                                                                Anne Baudry
                                                                ,
                                                                                                                                Luiz Ribeiro
                                                                ,
                                                                                                                                Hector Ardila-Osorio
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03413478
                                            v1
                                    
            
        
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    | 
        
                            
                    
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            Adenomyosis is associated with specific proton nuclear magnetic resonance (1H-NMR) serum metabolic profiles
        
                            
                                                                                                            Mathilde Bourdon
                                                                ,
                                                                                                                                Pietro Santulli
                                                                ,
                                                                                                                                Fatiha Kateb
                                                                ,
                                                                                                                                Khaled Pocate-Cheriet
                                                                ,
                                                                                                                                Frederic Batteux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684698
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The follicular fluid metabolome differs according to the endometriosis phenotype
        
                            
                                                                                                            Khaled Pocate-Cheriet
                                                                ,
                                                                                                                                Pietro Santulli
                                                                ,
                                                                                                                                Fatiha Kateb
                                                                ,
                                                                                                                                Mathilde Bourdon
                                                                ,
                                                                                                                                Chloé Maignien
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03493619
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Endometriosis phenotypes are associated with specific serum metabolic profiles determined by proton-nuclear magnetic resonance
        
                            
                                                                                                            Chloé Maignien
                                                                ,
                                                                                                                                Pietro Santulli
                                                                ,
                                                                                                                                Fatiha Kateb
                                                                ,
                                                                                                                                Cédric Caradeuc
                                                                ,
                                                                                                                                Louis Marcellin
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03492022
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Urinary metabolic profiling of asymptomatic acute intermittent porphyria using a rule-mining-based algorithm
        
                            
                                                                                                            Margaux Luck
                                                                ,
                                                                                                                                Caroline Schmitt
                                                                ,
                                                                                                                                Neila Talbi
                                                                ,
                                                                                                                                Laurent Gouya
                                                                ,
                                                                                                                                Cédric Caradeuc
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684742
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
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            Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment
        
                            
                                                                                                            Baptiste Fohlen
                                                                ,
                                                                                                                                Quentin Tavernier
                                                                ,
                                                                                                                                Thi-Mum Huynh
                                                                ,
                                                                                                                                Cédric Caradeuc
                                                                ,
                                                                                                                                Delphine Le Corre
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684748
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice
        
                            
                                                                                                            Céline Desseille
                                                                ,
                                                                                                                                Séverine Deforges
                                                                ,
                                                                                                                                Olivier Biondi
                                                                ,
                                                                                                                                Léo Houdebine
                                                                ,
                                                                                                                                Domenico D’amico
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684756
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
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            Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
        
                            
                                                                                                            Manal Sarkis
                                                                ,
                                                                                                                                Maria Miteva
                                                                ,
                                                                                                                                Maria Chiara Dasso Lang
                                                                ,
                                                                                                                                Maryse Jaouen
                                                                ,
                                                                                                                                Marie-Agnès Sari
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684762
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
        
                            
                                                                                                            Manal Sarkis
                                                                ,
                                                                                                                                Maria Miteva
                                                                ,
                                                                                                                                Maria Chiara Dasso Lang
                                                                ,
                                                                                                                                Maryse Jaouen
                                                                ,
                                                                                                                                Marie-Agnès Sari
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03689998
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Model of the Interaction between the NF-κB Inhibitory Protein p100 and the E3 Ubiquitin Ligase β-TrCP based on NMR and Docking Experiments
        
                            
                                                                                                            Maxime Melikian
                                                                ,
                                                                                                                                Baptiste Eluard
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Véronique Baud
                                                                ,
                                                                                                                                Nathalie Evrard-Todeschi
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684765
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
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            Interaction of a small molecule Natura-α and STAT3-SH2 domain to block Y705 phosphorylation and inhibit lupus nephritis
        
                            
                                                                                                            J.W. Chiao
                                                                ,
                                                                                                                                Maxime Melikian
                                                                ,
                                                                                                                                Liying Han
                                                                ,
                                                                                                                                Chengsen Xue
                                                                ,
                                                                                                                                Allen Tsao
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684776
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Rule-Mining for the Early Prediction of Chronic Kidney Disease Based on Metabolomics and Multi-Source Data
        
                            
                                                                                                            Margaux Luck
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Mathilde Bateson
                                                                ,
                                                                                                                                Alexandre Karras
                                                                ,
                                                                                                                                Anastasia Yartseva
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684770
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
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            Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.
        
                            
                                                                                                            Lionel Ducassou
                                                                ,
                                                                                                                                Gabriella Jonasson
                                                                ,
                                                                                                                                Laura Dhers
                                                                ,
                                                                                                                                Nicolas Pietrancosta
                                                                ,
                                                                                                                                Booma Ramassamy
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01449701
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            The urinary metabolome of chronic kidney disease
        
                            
                                                                                                            Nicolas Pallet
                                                                ,
                                                                                                                                Eric Thervet
                                                                ,
                                                                                                                                Philippe Beaune
                                                                ,
                                                                                                                                Alexandre Karras
                                                                ,
                                                                                                                                Gildas Bertho
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684819
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Urinary Metabolic Fingerprint of Acute Intermittent Porphyria Analyzed by 1 H NMR Spectroscopy
        
                            
                                                                                                            Mickael Carichon
                                                                ,
                                                                                                                                Nicolas Pallet
                                                                ,
                                                                                                                                Caroline Schmitt
                                                                ,
                                                                                                                                Thibaud Lefebvre
                                                                ,
                                                                                                                                Laurent Gouya
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684829
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Novel RANK Antagonists for the Treatment of Bone-Resorptive Disease: Theoretical Predictions and Experimental Validation
        
                            
                                                                                                            Stéphane Téletchéa
                                                                ,
                                                                                                                                Verena Stresing
                                                                ,
                                                                                                                                Soizic Hervouet
                                                                ,
                                                                                                                                Marc Baud'Huin
                                                                ,
                                                                                                                                Marie-Françoise Heymann
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-01644748
                                            v1
                                    
            
        
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    | 
        
                                                
     | 
        
        
            A new derivative detected in accelerated ageing of artesunate-amodiaquine fixed dose combination tablets
        
                            
                                                                                                            Cedric Charrier
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Olivier Petigny
                                                                ,
                                                                                                                                Philippe Moneton
                                                                ,
                                                                                                                                Robert Azerad
                                                                                    
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-03684836
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Thiolactone Sulfoxides as New Reactive Metabolites Acting as Bis-Electrophiles: Implication in Clopidogrel and Prasugrel Bioactivation
        
                            
                                                                                                            Patrick Dansette
                                                                ,
                                                                                                                                Dan Levent
                                                                ,
                                                                                                                                Assia Hessani
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684856
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Toward Stable Electron Paramagnetic Resonance Oximetry Probes: Synthesis, Characterization, and Metabolic Evaluation of New Ester Derivatives of a Tris-( para -carboxyltetrathiaaryl)methyl (TAM) Radical
        
                            
                                                                                                            Christophe Decroos
                                                                ,
                                                                                                                                Véronique Balland
                                                                ,
                                                                                                                                Jean-Luc Boucher
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Yun Xu-Li
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684842
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Tryptophan Depletion and the Kinase GCN2 Mediate IFN-γ–Induced Autophagy
        
                            
                                                                                                            Sophie Fougeray
                                                                ,
                                                                                                                                Iadh Mami
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Philippe Beaune
                                                                ,
                                                                                                                                Eric Thervet
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684891
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Naphthalene-dioxygenase catalysed cis-dihydroxylation of bicyclic azaarenes
        
                            
                                                                                                            Claude Chopard
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Thierry Prangé
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684941
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Contact-based ligand-clustering approach for the identification of active compounds in virtual screening
        
                            
                                                                                                            Gildas Bertho
                                                                ,
                                                                                                                                Alexey Mantsyzov
                                                                ,
                                                                                                                                Guillaume Bouvier
                                                                ,
                                                                                                                                Nathalie Evrard-Todeschi
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684866
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis
        
                            
                                                                                                            Patricia Rada
                                                                ,
                                                                                                                                Ana Rojo
                                                                ,
                                                                                                                                Nathalie Evrard-Todeschi
                                                                ,
                                                                                                                                Nadia Innamorato
                                                                ,
                                                                                                                                Axelle Cotte
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684929
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer
        
                            
                                                                                                            Patrick Dansette
                                                                ,
                                                                                                                                Julien Rosi
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684944
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Metabolic Activation of Prasugrel: Nature of the Two Competitive Pathways Resulting in the Opening of Its Thiophene Ring
        
                            
                                                                                                            Patrick Dansette
                                                                ,
                                                                                                                                Julien Rosi
                                                                ,
                                                                                                                                Justine Debernardi
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684932
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Paraoxonase-1 and clopidogrel efficacy
        
                            
                                                                                                            Patrick Dansette
                                                                ,
                                                                                                                                Julien Rosi
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684957
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Automatic clustering of docking poses in virtual screening process using self-organizing map
        
                            
                                                                                                            Guillaume Bouvier
                                                                ,
                                                                                                                                Nathalie Evrard-Todeschi
                                                                ,
                                                                                                                                Jean-Pierre Girault
                                                                ,
                                                                                                                                Gildas Bertho
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684971
                                            v1
                                    
            
        
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            Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel
        
                            
                                                                                                            Patrick Dansette
                                                                ,
                                                                                                                                Stéphanie Thébault
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684983
                                            v1
                                    
            
        
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            Oxidative and Reductive Metabolism of Tris( p -carboxyltetrathiaaryl)methyl Radicals by Liver Microsomes
        
                            
                                                                                                            Christophe Decroos
                                                                ,
                                                                                                                                Yun Li
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Yves Frapart
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684990
                                            v1
                                    
            
        
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            Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel
        
                            
                                                                                                            Patrick Dansette
                                                                ,
                                                                                                                                Julie Libraire
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03684993
                                            v1
                                    
            
        
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            Synthetic studies towards diazepanone scaffolds
        
                            
                                                                                                            Christophe Decroos
                                                                ,
                                                                                                                                Yun Li
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Yves Frapart
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-03685013
                                            v1
                                    
            
        
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            Oxidation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes: evidence for their oxidative decarboxylation and molecular origin of their specific ability to react with O2˙−
        
                            
                                                                                                            Christophe Decroos
                                                                ,
                                                                                                                                Yun Li
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Yves Frapart
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-02102841
                                            v1
                                    
            
        
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            Transfer-NMR and Docking Studies Identify the Binding of the Peptide Derived from Activating Transcription Factor 4 to Protein Ubiquitin Ligase β-TrCP. Competition STD-NMR with β-Catenin
        
                            
                                                                                                            Julien Pons
                                                                ,
                                                                                                                                Nathalie Evrard-Todeschi
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Josyane Gharbi-Benarous
                                                                ,
                                                                                                                                Valérie Tanchou
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-03685028
                                            v1
                                    
            
        
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            The key-role of tyrosine 155 in the mechanism of prion transconformation as highlighted by a study of sheep mutant peptides
        
                            
                                                                                                            Gildas Bertho
                                                                ,
                                                                                                                                Guillaume Bouvier
                                                                ,
                                                                                                                                Gaston Hui Bon Hoa
                                                                ,
                                                                                                                                Jean-Pierre Girault
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03685032
                                            v1
                                    
            
        
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            Diastereoselective Additions to (3S)-3-Aminodehydrocaprolactams: Development of a Versatile Synthesis of New Substituted CyclicL-Lysines
        
                            
                                                                                                            Camille Levraud
                                                                ,
                                                                                                                                Sandrine Calvet-Vitale
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Hamid Dhimane
                                                                                    
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-03685043
                                            v1
                                    
            
        
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            Structure of the Complex between Phosphorylated Substrates and the SCF β-TrCP Ubiquitin Ligase Receptor: A Combined NMR, Molecular Modeling, and Docking Approach
        
                            
                                                                                                            Nathalie Evrard-Todeschi
                                                                ,
                                                                                                                                Julien Pons
                                                                ,
                                                                                                                                Josyane Gharbi-Benarous
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Richard Benarous
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03685021
                                            v1
                                    
            
        
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            Efficient synthesis of polyfunctionalised enantiopure diazepanone scaffolds
        
                            
                                                                                                            Olivier Monasson
                                                                ,
                                                                                                                                Maryon Ginisty
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Christine Gravier-Pelletier
                                                                ,
                                                                                                                                Yves Le Merrer
                                                                                    
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-03685046
                                            v1
                                    
            
        
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            Allosteric tuning of the intra-cavity binding properties of a calix[6]arene through external binding to a Zn(II) center coordinated to amino arms
        
                            
                                                                                                            Ulrich Darbost
                                                                ,
                                                                                                                                Olivier Sénèque
                                                                ,
                                                                                                                                Yun Li
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Jerome Marrot
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-00391396
                                            v1
                                    
            
        
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            STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody.
        
                            
                                                                                                            Simon Megy
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Josyane Gharbi-Benarous
                                                                ,
                                                                                                                                Françoise Baleux
                                                                ,
                                                                                                                                Richard Benarous
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    pasteur-00166653
                                            v1
                                    
            
        
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            First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives
        
                            
                                                                                                            Patrick M. Dansette
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Daniel Mansuy
                                                                                    
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-00068627
                                            v1
                                    
            
        
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            Solution structure of a peptide derived from the oncogenic protein beta-Catenin in its phosphorylated and nonphosphorylated states.
        
                            
                                                                                                            Simon Megy
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Josyane Gharbi-Benarous
                                                                ,
                                                                                                                                Françoise Baleux
                                                                ,
                                                                                                                                Richard Benarous
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    pasteur-00166821
                                            v1
                                    
            
        
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            Possible role of region 152-156 in structural duality of a peptide fragment from sheep prion protein
        
                            
                                                                                                            Simon Megy
                                                                ,
                                                                                                                                Gildas Bertho
                                                                ,
                                                                                                                                Serguey A. Kozin
                                                                ,
                                                                                                                                Marie Pascale M. P. Debey
                                                                ,
                                                                                                                                Gaston Hui Bon Hoa
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02677622
                                            v1
                                    
            
        
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