|
NMR and DFT Studies with a Doubly Labelled 15 N/ 6 Li S ‐Trifluoromethyl Sulfoximine Reveal Why a Directed ortho ‐Lithiation Requires an Excess of n ‐BuLi
Matthieu Hédouin
,
Anne‐laure Barthelemy
,
Nicolas Vanthuyne
,
Hend Besrour
,
Jacques Maddaluno
et al.
Journal articles
hal-03912827v1
|
|
High pressure promoted dearomatization of nitroarenes by [4+2] cycloadditions with silyloxydienes
Batoul Rkein
,
Romain Coffinier
,
Marian Powderly
,
Maxime Manneveau
,
Morgane Sanselme
et al.
Journal articles
hal-03854290v1
|
|
Metabolic and Anti-Inflammatory Protective Properties of Human Enriched Serum Following Artichoke Leaf Extract Absorption: Results from an Innovative Ex Vivo Clinical Trial
Fabien Wauquier
,
Line Boutin-Wittrant
,
Aurélien Viret
,
Laure Guilhaudis
,
Hassan Oulyadi
et al.
Journal articles
hal-03326084v1
|
|
A mild and straightforward one-pot hyaluronic acid functionalization through termination of poly-(2-alkyl-2-oxazoline)
Mathieu Madau
,
Gaëlle Morandi
,
Christophe Rihouey
,
Vincent Lapinte
,
Hassan Oulyadi
et al.
Journal articles
hal-03343723v1
|
|
Bis(imino)carbazolate lead(II) fluoride and related halides
Peter M Chapple
,
Ghanem Hamdoun
,
Thierry Roisnel
,
Jean-François Carpentier
,
Hassan Oulyadi
et al.
Journal articles
hal-03282745v1
|
|
Bonding analysis in ytterbium(II) distannyl and related tetryls
Peter M Chapple
,
Julien Cartron
,
Ghanem Hamdoun
,
Marie Cordier
,
Samia Kahlal
et al.
Journal articles
hal-03369223v1
|
|
Metal-metal bonded alkaline-earth distannyls
Peter M. Chapple
,
Julien Cartron
,
Ghanem Hamdoun
,
Samia Kahlal
,
Marie Cordier
et al.
Journal articles
hal-03245118v1
|
|
Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1.
Asma Bourafai-Aziez
,
Mohammed Benabderrahmane
,
Hippolyte Paysant
,
Louis-Bastien Weiswald
,
Laurent Poulain
et al.
Journal articles
hal-03576776v1
|
|
Intertwined Analytical, Experimental and Theoretical Studies on the Formation and Structure of a Copper Dienolate
Baptiste Lecachey
,
Laetitia Palais
,
Benoît Courcy
,
Samira Bouauli
,
Muriel Durandetti
et al.
Journal articles
hal-03440070v1
|
|
Accurate measurement of effective Li–Li scalar coupling constants: the NMR missing link for alkyllithium aggregates
Matthieu Hedouin
,
Anne Harrison-Marchand
,
Jacques Maddaluno
,
Hassan Oulyadi
Journal articles
hal-03440027v1
|
|
Characterization of β-turns by electronic circular dichroism spectroscopy: A coupled molecular dynamics and time-dependent density functional theory computational study
Mattia Migliore
,
Andrea Bonvicini
,
Vincent Tognetti
,
Laure Guilhaudis
,
Marc Baaden
et al.
Journal articles
hal-02397135v1
|
|
S-glycosyltransferase UGT74B1 can glycosylate both S- and O-acceptors: mechanistic insights through substrate specificity
P. Lafite
,
Sami Marroun
,
Gaël Coadou
,
S. Montaut
,
S. Marques
et al.
Journal articles
hal-02330966v1
|
|
Binding mode of Pyridoclax to Myeloid cell leukemia-1 (Mcl-1) revealed by Nuclear Magnetic Resonance Spectroscopy, Docking and Molecular Dynamics Approaches
Asma Bourafai Aziez
,
Muriel Sebban
,
M. Benabderrahmane
,
B. Marekha
,
C. Denis
et al.
Journal articles
hal-02330946v1
|
|
Dearomatization of 3‐Nitroindoles with Highly γ‐Functionalized Allenoates in Formal (3+2) Cycloadditions
Léo Birbaum
,
Laurent Gillard
,
Hélène Gérard
,
Hassan Oulyadi
,
Guillaume Vincent
et al.
Journal articles
hal-02330833v1
|
|
First Direct Evidence of an ortho -Lithiated Aryloxetane: Solid and Solution Structure, and Dynamics
Filippo Perna
,
Aurelia Falcicchio
,
Antonio Salomone
,
Anne Milet
,
Rosanna Rizzi
et al.
Journal articles
hal-02294014v1
|
|
Rational design of carbamate-based dual binding site and central AChE inhibitors by a “biooxidisable” prodrug approach: Synthesis, in vitro evaluation and docking studies
Mihaela-Liliana Ţînţaş
,
Vincent Gembus
,
Florent Alix
,
Anaïs Barré
,
Gaël Coadou
et al.
Journal articles
hal-03134356v1
|
|
Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer's Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in Vitro Safety Pharmacology, and Preliminary in Vivo Toxicology Profile
F. Alix
,
V. Gembus
,
L. Coquet
,
Marie Hubert-Roux
,
P. Chan
et al.
Journal articles
hal-02024468v1
|
|
Recent Advances in NMR: Aggregation, Solvation, and Dynamics of Selected Organolithium Compounds
Hassan Oulyadi
Journal articles
hal-02024522v1
|
|
Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer’s Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in Vitro Safety Pharmacology, and Preliminary in Vivo Toxicology Profile
Florent Alix
,
Vincent Gembus
,
Laurent Coquet
,
Marie Hubert-Roux
,
Philippe Chan
et al.
Journal articles
hal-03134333v1
|
|
Rational design of carbamate-based dual binding site and central AChE inhibitors by a “biooxidisable” prodrug approach: Synthesis, in vitro evaluation and docking studies
Mihaela-Liliana Tîntas
,
Vincent Gembus
,
F. Alix
,
A. Barré
,
Gaël Coadou
et al.
Journal articles
hal-02024536v1
|
|
Stereoselective synthesis of functionalized vinyl ethers from allyl bromides activated by triethylamine
Aïcha Arfaoui
,
Fatma Saâdi
,
Asma Bourafai Aziez
,
Hammouda Chebbi
,
Catherine Fressigné
et al.
Journal articles
hal-02019141v1
|
|
Synthesis and Identification of Aryl and Alkyl Gem-Dilithium Phosphido-Boranes: A Boost to the Chemistry of Phosphandiides
Jie Guang
,
Romain Duwald
,
Jacques Maddaluno
,
Hassan Oulyadi
,
Sami Lakhdar
et al.
Journal articles
hal-01850334v1
|
|
Characterization of Milkisin, a Novel Lipopeptide With Antimicrobial Properties Produced By Pseudomonas sp. UCMA 17988 Isolated From Bovine Raw Milk
Margot Schlusselhuber
,
Justine Godard
,
Muriel Sebban
,
Benoit Bernay
,
David Garon
et al.
Journal articles
hal-02176304v1
|
|
Revisiting absorption and electronic circular dichroism spectra of cholesterol in solution: A joint experimental and theoretical study
Andrea Bonvicini
,
Laure Guilhaudis
,
Vincent Tognetti
,
D. Desmaële
,
N. Sauvonnet
et al.
Journal articles
hal-02024476v1
|
|
Phytochemical constituents from the seeds of Calycotome villosa subsp. intermedia
Aouicha Elkhamlichi
,
Ali El Antri
,
Hanane El Hajaji
,
Brahim El Bali
,
Hassan Oulyadi
et al.
Journal articles
hal-02046274v1
|
|
2D 7 Li Ultrafast CT-COSY: a new tool for the rapid measurement of tiny homonuclear lithium scalar couplings
Ghanem Hamdoun
,
B. Gouilleux
,
Muriel Sebban
,
Gabriella Barozzino-Consiglio
,
Anne Harrison-Marchand
et al.
Journal articles
hal-02019169v1
|
|
A Combined 1 H/ 6 Li NMR DOSY Strategy Finally Uncovers the Structure of Isopropyllithium in THF
Gabriella Barozzino-Consiglio
,
Ghanem Hamdoun
,
Catherine Fressigné
,
Anne Harrison-Marchand
,
Jacques Maddaluno
et al.
Journal articles
hal-02019154v1
|
|
Enantioselective Synthesis of Dideoxy-tetrafluorinated Hexoses
S. Golten
,
C.Q. Fontenelle
,
R.S. Timofte
,
Laura Bailac
,
M. Light
et al.
Journal articles
hal-02046210v1
|
|
UGT74B1 from Arabidopsis thaliana as a versatile biocatalyst for the synthesis of desulfoglycosinolates
Sami Marroun
,
Sabine Montaut
,
Stéphanie Marquès
,
Pierre Lafite
,
Gaël Coadou
et al.
Journal articles
hal-02046226v1
|
|
Radical Cyclisation of α-Halo Aluminium Acetals: A Mechanistic Study
R. Bénéteau
,
A. Boussonnière
,
J.-C. Rouaud
,
Jacques Lebreton
,
J. Graton
et al.
Journal articles
hal-02046185v1
|
|
Alkyllithium Mixed Aggregates: Dynamic Behavior and Comprehensive Analysis of NMR 2 J 7 Li– 7 Li Spin–Spin Coupling
Ghanem Hamdoun
,
Muriel Sebban
,
Vincent Tognetti
,
Anne Harrison-Marchand
,
Laurent Joubert
et al.
Journal articles
hal-02019285v1
|
|
Organocatalyzed Multicomponent Synthesis of Isoxazolidin-5-ones
Christophe Berini
,
Muriel Sebban
,
Hassan Oulyadi
,
Morgane Sanselme
,
Vincent Levacher
et al.
Journal articles
hal-02046141v1
|
|
Evaluation of atmospheric solid analysis probe ionization coupled to ion mobility mass spectrometry for characterization of poly(ether ether ketone) polymers
Emilie Cossoul
,
Marie Hubert-Roux
,
Muriel Sebban
,
Florence Churlaud
,
Hassan Oulyadi
et al.
Journal articles
hal-01107933v1
|
|
Enantioselective Alkynylation of Aldehydes by Mixed Aggregates of 3-Aminopyrrolidine Lithium Amides and Lithium Acetylides
Gabriella Barozzino-Consiglio
,
Yi Yuan
,
Catherine Fressigné
,
Anne Harrison-Marchand
,
Hassan Oulyadi
et al.
Journal articles
hal-02019204v1
|
|
Probing solvent effects on mixed aggregates associating a chiral lithium amide and n-BuLi by NMR: from structure to reactivity
Gabriella Barozzino-Consiglio
,
Mathieu Rouen
,
Hassan Oulyadi
,
Anne Harrison-Marchand
,
Jacques Maddaluno
et al.
Journal articles
hal-01144757v1
|
|
1 H Pure Shift DOSY: a handy tool to evaluate the aggregation and solvation of organolithium derivatives
Ghanem Hamdoun
,
Muriel Sebban
,
E. Cossoul
,
Anne Harrison-Marchand
,
Jacques Maddaluno
et al.
Journal articles
hal-02019298v1
|
|
Glycine-modified polyamidoamine dendrimers: synthesis and structural characterization using nuclear magnetic resonance, ion-mobility mass spectrometry and capillary electrophoresis
Emma-Dune Leriche
,
Carlos Afonso
,
Catherine M. Lange
,
Martin Christopher Grossel
,
Lina Truong
et al.
Journal articles
hal-01016931v1
|
|
Conformation control of abiotic α-helical foldamers
Serge Perato
,
Jade Fogha
,
Muriel Sebban
,
Anne-Sophie Voisin-Chiret
,
Jana Sopkova-de Oliveira Santos
et al.
Journal articles
hal-00918423v1
|
|
Structure of the Mixed Aggregates between a Chiral Lithium Amide and Phenyllithium or Vinyllithium
Hassan Oulyadi
,
Catherine Fressigné
,
Yi Yuan
,
Jacques Maddaluno
,
Anne Harrison-Marchand
et al.
Journal articles
hal-01015955v1
|
|
Synthesis of new linear poly(phenylpyridyl) chains
Serge Perato
,
Anne-Sophie Voisin-Chiret
,
Jana Sopkova-de Oliveira Santos
,
Rémi Legay
,
Hassan Oulyadi
et al.
Journal articles
hal-01015920v1
|
|
Structural characterizations of oligopyridyl foldamers, α-helix mimetics
Jana Sopkova-de Oliveira Santos
,
Anne-Sophie Voisin-Chiret
,
Grégory Burzicki
,
Laure Sebaoun
,
Muriel Sebban
et al.
Journal articles
hal-00996400v1
|
|
Studies on pyrrolidinones. Reaction of pyroglutamic acid and vinylogues with aromatics in Eaton's reagent
Alina Ghinet
,
Nathalie van Hijfte
,
Philippe Gautret
,
Benoit Rigot
,
Hassan Oulyadi
et al.
Journal articles
hal-01015963v1
|
|
Synthesis and structural characterization of a liquid polyisoprene bearing amidoxime end groups
Fabrice Burel
,
Hassan Oulyadi
,
Claude Bunel
,
Vladimir Grishchenko
,
Natalya Busko
et al.
Journal articles
hal-02326486v1
|
|
The conformation of tetrafluorinated methyl galactoside anomers: crystallographic and NMR studies.
Bruno Linclau
,
Samuel Golten
,
Mark Light
,
Muriel Sebban
,
Hassan Oulyadi
et al.
Journal articles
hal-00991612v1
|
|
Ph2P(BH3)Li: from ditopicity to dual reactivity.
Gabriella Barozzino Consiglio
,
Pierre Queval
,
Anne Harrison-Marchand
,
Alessandro Mordini
,
Jean-François Lohier
et al.
Journal articles
hal-00991604v1
|
|
First substoichiometric version of the catalytic enantioselective addition of an alkyllithium to an aldehyde.
Baptiste Lecachey
,
Catherine Fressigné
,
Hassan Oulyadi
,
Anne Harrison-Marchand
,
Jacques Maddaluno
et al.
Journal articles
hal-00991609v1
|
|
Study of interaction between tiagabine HCl and 2-HPβCD: Investigation of inclusion process
Abdussalam Sughir
,
Mohamed Skiba
,
Pedro Lameiras
,
Gaël Coadou
,
Malika Lahiani-Skiba
et al.
Journal articles
hal-01018540v1
|
|
MeLi + LiCl in THF: one heterodimer and no tetramers.
Baptiste Lecachey
,
Hassan Oulyadi
,
Pedro Lameiras
,
Anne Harrison-Marchand
,
Hélène Gérard
et al.
Journal articles
hal-00991692v1
|
|
NMR studies of a ternary complex reagent of lithium ester enolate, chiral diether, and lithium diisopropylamide in an asymmetric Michael reaction
Yasumoto Yamamoto
,
Yorinobu Yasuda
,
Hassan Oulyadi
,
Jacques Maddaluno
,
Kiyoshi Tomioka
et al.
Journal articles
hal-01018385v1
|
|
Unexpected reversible nitrogen atom transfer in the synthesis of polysubstituted imides and 7-aza-hexahydroindolones via enaminonitrile γ-lactams
Nabila Oukli
,
Sébastien Comesse
,
Nafa Chafi
,
Hassan Oulyadi
,
Adam Daïch
et al.
Journal articles
hal-02564911v1
|
|
Enantioselective Conjugate Addition of a Lithium Ester Enolate Catalyzed by Chiral Lithium Amides: A Possible Intermediate Characterized
Baptiste Lecachey
,
Nicolas Duguet
,
Hassan Oulyadi
,
Catherine Fressigné
,
Anne Harrison-Marchand
et al.
Journal articles
hal-02357660v1
|
|
Structure–activity relationships of urotensin II and URP
Jérôme Leprince
,
David Chatenet
,
Christophe Dubessy
,
Alain Fournier
,
Bruno Pfeiffer
et al.
Journal articles
hal-01972605v1
|
|
New structural features of Spondias purpurea gum exudate
M. Martínez
,
G. León de Pinto
,
M. Bozo de González
,
J. Herrera
,
Hassan Oulyadi
et al.
Journal articles
hal-02352021v1
|
|
Study of the in vitro degradation of poly(ethyl glyoxylate)
Benjamine Belloncle
,
Fabrice Burel
,
Hassan Oulyadi
,
Claude Bunel
Journal articles
hal-02326435v1
|
|
Solution structure of urotensin-II receptor extracellular loop III and characterization of its interaction with urotensin-II
Stéphane Boivin
,
Isabelle Ségalas-Milazzo
,
Laure Guilhaudis
,
Hassan Oulyadi
,
Alain Fournier
et al.
Journal articles
hal-02352152v1
|
|
Definition of New Pharmacophores for Nonpeptide Antagonists of Human Urotensin-II. Comparison with the 3D-structure of Human Urotensin-II and URP
Elodie Lescot
,
Jana Sopkova-de Oliveira Santos
,
Christophe Dubessy
,
Hassan Oulyadi
,
Aurélien Lesnard
et al.
Journal articles
hal-02179719v1
|
|
Origin of the Detrimental Effect of Lithium Halides on an Enantioselective Nucleophilic Alkylation of Aldehydes
Franck Paté
,
Nicolas Duguet
,
Hassan Oulyadi
,
Anne Harrison-Marchand
,
Catherine Fressigné
et al.
Journal articles
hal-02357639v1
|
|
New sythesis of cis 5-tert-butyl-L-proline via cuprate. Evaluation as a cis proline mimetic in a biological active octapeptide.
Carine Aubry
,
Hassan Oulyadi
,
Guillaume Dutheuil
,
Jérôme Leprince
,
Hubert Vaudry
et al.
Journal of Peptide Science, 2006, 12(2), pp.154-160
Journal articles
hal-00023722v1
|
|
3-Aminopyrrolidine lithium amides as chiral ligands for alkyllithium derivatives: Synthesis, NMR analysis, and computational study of their mixed aggregates
Anne Harrison-Marchand
,
Jean-Yves Valnot
,
Aline Corruble
,
Nicolas Duguet
,
Hassan Oulyadi
et al.
Journal articles
hal-02357634v1
|
|
Tandem Michael Addition/Amino-Nitrile Cyclization from 2-Formyl-1,4-DHP in the Synthesis of Novel Dihydroindolizine-Based Compounds
Štefan Marchalín
,
Barbora Baumlová
,
Peter Baran
,
Hassan Oulyadi
,
Adam Daïch
et al.
Journal articles
hal-02564930v1
|
|
Characterization of urotensin-II receptor structural domains involved in the recognition of U-II, URP, and urantide.
Stéphane Boivin
,
Laure Guilhaudis
,
Isabelle Milazzo
,
Hassan Oulyadi
,
Daniel Davoust
et al.
Journal articles
pasteur-00820020v1
|
|
Access to substituted thiapyrrolizidinones and fused pyridones using the domino N-acyliminium-thionium equilibrium/1,3-dipolar cycloaddition/desulfurization cyclization cascade
Abdulkareem Hamid
,
Hassan Oulyadi
,
Adam Daïch
Journal articles
hal-02564933v1
|
|
Aryldithioethyloxycarbonyl (Ardec): A New Family of Amine Protecting Groups Removable under Mild Reducing Conditions and Their Applications to Peptide Synthesis
Milaine Lapeyre
,
Jérôme Leprince
,
Marc Massonneau
,
Hassan Oulyadi
,
Pierre-Yves Renard
et al.
Journal articles
hal-01962803v1
|
|
Aryldithioethyloxycarbonyl(Ardec) : a new family of aminoe protecting groups removable under mild reducing conditions and their applications to peptide synthesis.
M. Lapeyre
,
Jérôme Leprince
,
M. Massonneau
,
Hassan Oulyadi
,
Pierre-Yves Renard
et al.
Chemistry - A European Journal, 2006, 12, pp.3655-3671
Journal articles
hal-00023718v1
|
|
New synthesis ofcis 5-tert-butyl-L-proline via cuprate. Evaluation as acis proline mimetic in a biological active octapeptide
Carine Aubry
,
Hassan Oulyadi
,
Guillaume Dutheuil
,
Jérôme Leprince
,
Hubert Vaudry
et al.
Journal articles
hal-01960646v1
|
|
Structural studies on 26RFa, a novel human RFamide-related peptide with orexigenic activity
Romain Thuau
,
Laure Guilhaudis
,
Isabelle Ségalas-Milazzo
,
Nicolas Chartrel
,
Hassan Oulyadi
et al.
Journal articles
hal-01974257v1
|
|
Solvent effects on the mixed aggregates of chiral 3-aminopyrrolidine lithium amides and alkyllithiums
Yi Yuan
,
Stéphanie Desjardins
,
Anne Harrison-Marchand
,
Hassan Oulyadi
,
Catherine Fressigné
et al.
Journal articles
hal-02357618v1
|
|
New Resolution of 2-Formyl-1,4-DHP Derivatives Using CIDR Methodology. Facile Access to New Chiral Tricyclic Thiolactam
Štefan Marchalín
,
Katarína Cvopová
,
Miroslav Križ
,
Peter Baran
,
Hassan Oulyadi
et al.
Journal articles
hal-02564945v1
|
|
Structure–activity relationships and structural conformation of a novel urotensin II-related peptide
David Chatenet
,
Christophe Dubessy
,
Jérôme Leprince
,
Cédric Boularan
,
Ludovic Carlier
et al.
Journal articles
hal-01960815v1
|
|
Selective access and full characterization of mono-acidic permethylated β-cyclodextrin derivatives and their methyl esters
Séverine Tisse
,
Valérie Peulon-Agasse
,
Hassan Oulyadi
,
Francis Marsais
,
Jean-Claude Combret
et al.
Journal articles
hal-01936109v1
|
|
Synthesis and biological testing of 3-phenyloctahydro-pyrimido[1,2- a ]- s -triazine derivatives
Line Lucry
,
Ferdinand Enoma
,
François Estour
,
Sabine Ménager
,
Olivier Lafont
et al.
Journal articles
hal-02375741v1
|
|
A NMR and Theoretical Study of the Aggregates between Alkyllithium and Chiral Lithium Amides: Control of the Topology through a Single Asymmetric Center
Aline Corruble
,
Daniel Davoust
,
Stéphanie Desjardins
,
Catherine Fressigné
,
Claude Giessner-Prettre
et al.
Journal articles
hal-02357615v1
|
|
Chiral recognition of binaphthyl derivatives: A chiral recognition model on the basis of chromatography, spectroscopy, and molecular mechanistic calculations for the enantioseparation of 1,1?-binaphthyl derivatives on cholic acid-bonded stationary phases
L. Vaton-Chanvrier
,
Hassan Oulyadi
,
Y. Combret
,
G. Coquerel
,
J.C. Combret
et al.
Journal articles
hal-01936474v1
|
|
Synthesis of the three isomeric mono-2-, 3-, or 6-hydroxy permethylated β-cyclodextrins and unambiguous high field NMR characterisation
Hervé Cousin
,
Pascal Cardinaël
,
Hassan Oulyadi
,
Xavier Pannecoucke
,
Jean Claude Combret
et al.
Journal articles
hal-01936487v1
|
|
Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN. Design of a potent endozepine antagonist.
Jérôme Leprince
,
M. Leprince
,
Hassan Oulyadi
,
D. Vaudry
,
M. Masmoudi
et al.
Journal articles
hal-01972542v1
|
|
Synthèse et activité biologique d’analogues de l’octadécaneuropeptide (ODN), ligand endogène potentiel des récepteurs des benzodiazépines. Etudes des relations structure-activité.
Jérôme Leprince
,
Marie-Christine Tonon
,
Hassan Oulyadi
,
Estelle Bouron
,
Jean-Luc Fauchère
et al.
Actualités de Chimie Thérapeutique, 2000
Journal articles
hal-01972565v1
|