Hervé Acloque
- Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
- Génétique Animale et Biologie Intégrative (GABI)
Présentation
PERSONALINFORMATION Family name, First name: ACLOQUE Hervé Researcher unique identifier(s): http:/orcid.org/0000-0003-4761-1055 Date of birth: 28th of February, 1976 Nationality: French https://www.researchgate.net/profile/Herve_Acloque EDUCATION 2004 PhD in Life Sciences obtained April 30th, 2004 (Ph.D. supervisor: Pr. Jacques Samarut) Ecole Normale Supérieure de Lyon, UMR5665, Laboratoire de Biologie Moléculaire et Cellulaire, France CURRENTPOSITION 2021 – present INRAE, Group Leader UMR1313 GABI, team Functional Genomics for Animal Health (EFISA) PREVIOUS POSITIONS 2018 – 2021 INRA, Senior Scientist UMR1313 GABI, team Genetic, Immunity, Animal Health 2015 – 2019 INRA, Principal Investigator at the UMRS935 ESTeam, Models of malignant and therapeutic stem cells, Villejuif, France 2010 – 2018 INRA, Senior Scientist (Chargé de Recherche 1ere classe), UMR1388 GenPhySE, CYTOGENE team, Toulouse, France 2004 – 2009 Post-doctoral Fellow. Developmental Neurobiology Dpt., Instituto de Neurociencias de Alicante, CSIC, Team of Pr. Angela Nieto, Spain 2009 Visiting Scientist. Anatomy and Developmental Biology Dpt., University College of London, Team of Pr. Claudio Stern, UK 1999 – 2004 PhD Fellow. Laboratory of Molecular and Cellular Biology, Ecole Normale Supérieure de Lyon, Team of Pr. Jacques Samarut, France 1998-1999 Graduate Student (M.Sc) Department of Animal Physiology, Laboratory of Developmental Biology and Biotechnology, INRA, Team of Pr. Jean Paul Renard, Jouy en Josas, France TEACHING ACTIVITIES 2018- present Master program PRIAM (8h): Epigenetics/ Animal experimentation 2016 -present Master program IFSBM (4h): Cell Reprogramming, Université Paris Saclay, France 2016 -present Master program BME (4h): Mammalian Stem Cells, Université Paris Sorbonne, France 2012 – 2014 Master program (16h) – Developmental and Cellular Biology, Toulouse University, France 2008 – 2009 PhD program (20h) – Developmental Biology, University Miguel Hernandez, Instituto de Neurociencias, Spain 2002 – 2003 Supply Teacher (60h) – General Biology, Lyon University, France ** INSTITUTIONALRESPONSIBILITIES** 2021 - present Head of the team Functional Genomics for Animal Health (EFISA) 2020 - present 2017 – present Member of the Ethical Committee CEEA26 2019 - 2024t Nominated member of the Scientific Advisory Board of the INRA Animal Physiology and Livestock Systems (PHASE) Division 2017 - 2022 Elected member of the Scientific Advisory Board of the INRA Animal Genetics Division 2012–present GraduateStudentAdvisor (PhD committee): 7 PhD students from Lyon University (Stem Cells and Brain Research Institute), 3 PhD students from Toulouse University (Center for Integrative Biology, GenPhySE) and one from Paris-Saclay University (UMR935) 2014 Head of the CYTOGENE team composed of 7 permanent scientists, 7 technicians and engineers, 5 PhD students, post-docs and undergraduate students and a facility (4 people) for cytogenetic diagnostics in livestock species. 2012 Member of the scientific Committee for the restructuration of an experimental unit dedicated to pig reproduction and genetics
Compétences
Publications
Publications
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Detection of titanium nanoparticles in human, animal and infant formula milk.11th International Conference on Nanotoxicology (NanoTox), Sep 2024, VENISE, Italy |
Impact of the ingestion of titanium dioxide nanoparticles via breast milk on the respiratory health of young rabbits.Journées de recherche respiratoire, Oct 2023, Tours, France |
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Gene regulatory networks inference in the pigs embryos from scRNAseq and scMulti-omicsISMB 2023, Jul 2023, Lyon, France |
Deciphering the molecular network controlling the biology of the pig blastocyst and its cellular interactionsJournées Ouvertes en Biologie, Informatique et Mathématiques (JOBIM), Jul 2022, Rennes, France |
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Selection of cell lines for the functional validation of 3D genomic interactions by genome editing23. International Colloquium on Animal Cytogenetics and Genomics (23 ICACG), Jun 2018, St Petersbourg, Russia. Pensoft Publishers, 12 (3), 360 p., 2018, 23rd International Colloquium on Animal Cytogenetics and Genomics (23 ICACG) |
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Characterization of 3D genomic interactions in fetal pig muscle36th International Society for Animal Genetics Conference, Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book |
Integrative and differential analysis of transcriptomes and chromatin accessibility regions reveals regulatory mechanisms involved in pig immune and metabolic functions36th International Society for Animal Genetics Conference, Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book |
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Modifications ciblées des génomes: apports et impacts potentiels des nouvelles technologies pour les espèces aviaires12. Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, Apr 2017, Tours, France. ITAVI - Institut Technique de l'Aviculture, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, 12, 2017, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras |
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Une nouvelle facette du génome de poule : les genes “longs non-codants12. Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, Apr 2017, Tours, France. ITAVI - Institut Technique de l'Aviculture, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, 2017, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras |
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Long-non coding RNAs repertoires in liver and two T lymphocyte cell types in four livestock species36. Conference of the International Society for Animal Genetics (ISAG), Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book |
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Profiling the landscape of transcription, chromatin accessibility and chromosome conformation of cattle, pig, chicken and goat genomes [FAANG pilot project]36th International Society for Animal Genetics Conference, Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book |
Construction of whole genome interaction maps and study of correlation with gene expression level in fetal muscle cells22. International Colloquim on Animal Cytogenetics and Genomics (ICACG), Jul 2016, Toulouse, France. INRA - INP - ENVT, Chromosome Research, 24 (S1), 116 p., 2016, 22nd International Colloquim on Animal Cytogenetics and Genomics |
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Meiotic pairing and gene expression disturbance in germ cells from an infertile boar with a balanced reciprocal autosome-autosome translocation22. International Colloquium on Animal Cytogenetics and Genomics (ICACG), Jul 2016, Toulouse, France. INRA - INP - ENVT, Chromosome Research, 24 (S1), 116 p., 2016, Chromosome Research |
Long-non coding RNAs repertoire in liver and adipose tissue in chickenXXIV International Plant & Animal Genome (Pag), Jan 2016, San Diego, United States. 2016 |
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3D nuclear positioning of IGF2 alleles and trans interactions with imprinted genes in pig fetal cellsConference on Genome Architecture in Space and Time, Jun 2016, Trieste, Italy. 2016 |
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Sampling tissue for FAANG: the example of cattle and chickens in FranceGO-FAANG Workshop, Oct 2015, Washington DC, United States. , 1 p., 2015 |
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Chromosomal causes of impaired reproductive performance in swineAmerican Association of Swine Veterinarians, Mar 2015, Orlando, United States. , 2015 |
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Methylation levels at the GNAS locus is not associated with field fertility in Holstein bullsEpiconcept Workshop 2015 Periconception Environnement, Apr 2015, Dubrovnik, Croatia. COST Edition, 60 p., 2015, Epigenetics and Periconception Environment |
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Arcitecture nucléaire 3D et expression du génomeSéminaire du Departement de Génétique Animale, Apr 2014, Fréjus, France. 2013 |
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Derivation of induced pluripotent stem cells from an infertile boar carrying a reciprocal translocationConference 2014 Epiconcept "Epigenetics and Periconception Environment", Oct 2014, Vilamoura, Portugal. COST Office European Cooperation in Science and Technology (Portugal), 2014, Proceedings of the EPICONCEPT Conference 2014 - COST Action FA1201 |
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DNA methylation analysis in sperm from infertile/subfertile boarsJacques Monod Conference, Sep 2014, Roscoff, France. 2013 |
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DNA methylation analysis in sperm from infertile/subfertile boars33. Conference of the International Society of Animal Genetics ISAG, Jul 2012, Cairns, Australia. 2012, 33rd Conference of the International Society for Animal Genetics |
Inducing Sequential Cycles of Epithelial-Mesenchymal and Mesenchymal-Epithelial Transitions in Mammary Epithelial CellsThe Epithelial-to Mesenchymal Transition, pp.341-351, 2021, ⟨10.1007/978-1-0716-0779-4_26⟩ |
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In Situ Hybridization Analysis of Chick Embryos in Whole-Mount and Tissue SectionsAvian Embryology, 2nd edition, pp.169-185, 2008, ⟨10.1016/S0091-679X(08)00209-4⟩ |
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IDENTIFICATION ET CARACTERISATION MOLECULAIRE D'UNE NOUVELLE FAMILLE DE GENES MARQUEURS DES CELLULES SOUCHES EMBRYONNAIRES DE POULETSciences du Vivant [q-bio]. Université Claude Bernard Lyon 1, 2003. Français. ⟨NNT : ⟩ |
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Caractérisation des propriétés souches des cellules de vertébrés : conservation et spécificité entre cellules embryonnaires et cellules tumoralesSciences du Vivant [q-bio]. Institut National Polytechnique (Toulouse), 2015 |