Hervé Acloque
111
Documents
Présentation
**PERSONALINFORMATION**
Family name, First name: ACLOQUE Hervé
Researcher unique identifier(s): http:/orcid.org/0000-0003-4761-1055
Date of birth: 28th of February, 1976
Nationality: French
[https://www.researchgate.net/profile/Herve\_Acloque](https://www.researchgate.net/profile/Herve_Acloque)
**EDUCATION**
2004 PhD in Life Sciences obtained April 30th, 2004 (Ph.D. supervisor: Pr. Jacques Samarut)
Ecole Normale Supérieure de Lyon, UMR5665, Laboratoire de Biologie Moléculaire et Cellulaire, France
**CURRENTPOSITION**
2018 – present INRA, Senior Scientist UMR1313 GABI, team Genetic, Immunity, Animal Health
**PREVIOUS POSITIONS**
2015 – 2019 INRA, Principal Investigator at the UMRS935 ESTeam, Models of malignant and therapeutic stem cells, Villejuif, France
2010 – 2018 INRA, Senior Scientist (Chargé de Recherche 1ere classe), UMR1388 GenPhySE, CYTOGENE team, Toulouse, France
2004 – 2009 Post-doctoral Fellow. Developmental Neurobiology Dpt., Instituto de Neurociencias de Alicante, CSIC, Team of Pr. Angela Nieto, Spain
2009 Visiting Scientist. Anatomy and Developmental Biology Dpt., University College of London, Team of Pr. Claudio Stern, UK
1999 – 2004 PhD Fellow. Laboratory of Molecular and Cellular Biology, Ecole Normale Supérieure de Lyon, Team of Pr. Jacques Samarut, France
1998-1999 Graduate Student (M.Sc) Department of Animal Physiology, Laboratory of Developmental Biology and Biotechnology, INRA, Team of Pr. Jean Paul Renard, Jouy en Josas, France
**TEACHING ACTIVITIES**
2012 – 2014 Master program (16h) – Developmental and Cellular Biology, Toulouse University, France
2008 – 2009 PhD program (20h) – Developmental Biology, University Miguel Hernandez, Instituto de Neurociencias, Spain
2002 – 2003 Supply Teacher (60h) – General Biology, Lyon University, France
INSTITUTIONALRESPONSIBILITIES**
2019-present Nominated member of the Scientific Advisory Board of the INRA Animal Physiology and Livestock Systems (PHASE) Division
2017-present Elected member of the Scientific Advisory Board of the INRA Animal Genetics Division
2017 – presentMember of the Ethical Committee CEEA26
2012–presentGraduateStudentAdvisor (PhD committee): 7 PhD students from Lyon University (Stem Cells and Brain Research Institute), 3 PhD students from Toulouse University (Center for Integrative Biology, GenPhySE) and one from Paris-Saclay University (UMR935)
2014 Head of the CYTOGENE team composed of 7 permanent scientists, 7 technicians and engineers, 5 PhD students, post-docs and undergraduate students and a facility (4 people) for cytogenetic diagnostics in livestock species.
2012 Member of the scientific Committee for the restructuration of an experimental unit dedicated to pig reproduction and genetics
Publications
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Réseaux de gènes contrôlant la biologie de l'embryon de porc préimplantatoire et des cellules souches pluripotentes révélées par une approche multi-omiques à l’échelle cellule uniqueMeeting EPIPHASE, vincent coustham; nathalie beaujean, Oct 2023, Jouy en Josas, Yvelines, France
Communication dans un congrès
hal-04424207v1
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Samples collection and assays-by-sequence provided to the scientific communityFinal conference of the GENE-SWitCH project, EAAP; INRAE; INRAE-T, Nov 2023, Brussels, Belgium
Communication dans un congrès
hal-04498288v1
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Gene networks controlling functional cell interactions in the pig embryo revealed by omics studiesEAAP Annual Meeting, EAAP, Aug 2023, Lyon, France
Communication dans un congrès
hal-04424850v1
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French avian cryobank: development of reproductive biotechnologies based on primordial germ cells (PGCs) and investigation of the impact of in vitro steps on PGCs integrity and reproductive capacity26è World's Poultry Congress,, May 2022, Webinar, France
Communication dans un congrès
hal-04276115v1
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RNA-seq data for detecting reliable SNPs & genotypes in livestock species: interest for coding variant characterization and cis-regulation analysis by allele-specific expression !World Poultry Congress (WPC) 2022, Aug 2022, Paris, France
Communication dans un congrès
hal-04258396v1
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Cellules germinales primordiales aviaires au cœur des avancées de la conservation des ressources génétiques et de l’édition des génomes. L’exemple français14. Journées de la Recherche Avicole et Palmipèdes à Foie Gras, Mar 2022, Tours, France. pp.115-123
Communication dans un congrès
hal-04275281v1
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FR-Agencode: An UpdateThe Plant and Animal Genome XXVII Conference (PAG), Jan 2019, San Diego, United States
Communication dans un congrès
hal-03364351v1
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Functional annotation of livestock genomes: chromatin structure and regulation of gene expressionASAS/ASDS Midwest Joint Meeting, Mar 2019, Omaha, United States. ⟨10.1093/jas/skz122.028⟩
Communication dans un congrès
hal-02735898v1
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Multi-level conservation of chromosome conformation across livestock species reveals evolutionary links between genome structure and functionConference of the International Society for Animal Genetics (ISAG 2019), Jul 2019, Lleida, Spain
Communication dans un congrès
hal-02788476v1
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An atlas of chicken long non-coding RNAs gathering multiple sources : gene models and expression across more than twenty tissuesPAG XXVII - Plant & Animal Genome Conference, Jan 2019, San Diego, United States
Communication dans un congrès
hal-02790912v1
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Chromatin accessibility conservation across four livestock speciesConference of the International Society for Animal Genetics (ISAG 2019), Jul 2019, Llieda, Spain
Communication dans un congrès
hal-02788732v1
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Meiotic and gene expression analyses in a case of t(1;15) azoospermic boar23. International Colloquium on Animal Cytogenetics and Genomics (23 ICACG), Jun 2018, Saint-Pétersburg, Russia. 360 p
Communication dans un congrès
hal-02737986v1
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Single cell transcriptome in chronic myeloid leukemia (cml): pseudotime analysis reveals a rare population with embryonic stem cell features and druggable intricated transitional stem cell states60th Annual Meeting of the American-Society-of-Hematology (ASH), American Society of Hematology (ASH). USA., Dec 2018, San Diego, United States. pp.3, ⟨10.1182/blood-2018-99-110679⟩
Communication dans un congrès
hal-02733753v1
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Analyse transcriptomique cellule-unique pour définir les populations cellulaires pluripotentes et extra-embryonnaires et leurs interactions dans le blastocyste porcinJournées Scientifiques du Département de Génétique Animale, Oct 2018, Dienné, France. 1 p
Communication dans un congrès
hal-02786299v1
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Generating 3D organoid-like structures from porcine induced pluripotent-like cells in vitro.11. Symposium of the French Domestic Animal Immunology Network,, Mar 2018, Tours, France
Communication dans un congrès
hal-02918626v1
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Profiling the landscape of transcription and chromatin conformation reveals regulatory mechanisms involved in immune and metabolic functions3. Journée de Séminaires du Département Phase sur l'Epigénétique EpiPhase, May 2017, Jouy-en-Josas, France
Communication dans un congrès
hal-01603057v1
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Characterization of 3D genomic interactions in fetal pig muscle36. International Society for Animal Genetics Conference (ISAG), Jul 2017, Dublin, Ireland. pp.43
Communication dans un congrès
hal-02868765v1
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Comparison of Sperm Methylome in Fertile and Infertile Boars Carriers of DNA TranslocationPAG - Plant Animal Genome, Jan 2016, San Diego, United States
Communication dans un congrès
hal-02793883v1
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Profiling the Nuclear Spatial Conformation of Livestock Genomes in Cell Lines and Liver CellsPAG XXIV - Plant and Animal Genome Conference, Jan 2016, San Diego, United States. Non paginé
Communication dans un congrès
hal-01508146v1
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Investigating the nuclear spatial conformation of livestock genomes using Hi-CNGS'16 Genome Annotation, Apr 2016, Barcelone, Spain
Communication dans un congrès
hal-01581540v1
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3D nuclear positioning of IGF2 alleles and trans interactions with imprinted genes35. Conference of the International Society for Animal Genetics (ISAG), Jul 2016, Salt Lake City, United States
Communication dans un congrès
hal-02742818v1
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Analyse du comportement méiotique d'une translocation équilibrée réciproque autosome-autosome : une étude de cas chez le porc2. Réunion d'Animation épiPHASE, Institut National de Recherche Agronomique (INRA). UAR Département Physiologie Animale et Systèmes d'Elevage (0558)., Mar 2016, Saint-Pée-sur-Nivelle, France
Communication dans un congrès
hal-02801341v1
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3D nuclear positioning of IGF2 alleles and trans interactions with imprinted genes in pig fetal cells22. International Colloquim on Animal Cytogenetics and Genomics (ICACG), Jul 2016, Toulouse, France. 116 p
Communication dans un congrès
hal-02743243v1
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Effects of balanced chromosome translocations on boar fertility and cell reprogramming22. International Colloquium on Animal Cytogenetics and Genomics (ICACG), Jul 2016, Toulouse, France. 116p
Communication dans un congrès
hal-02738753v1
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Effects of chromosomal translocations on DNA methylation and consequences on spermatogenesis in the germline of male pigs10. European Cytogenetics Conference - ECA -, Jul 2015, Strasbourg, France
Communication dans un congrès
hal-02792088v1
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Analysis of male infertility: a case study in pigs21. International Colloquium on Animal Cytogenetics and Gene mapping, Jun 2014, Ischia, Italy. ⟨10.1007/s10577-014-9435-7⟩
Communication dans un congrès
hal-02742348v1
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Sperm DNA methylation analysis in swine reveals conserved and species-specific methylation patterns and highlights an altered methylation at the GNAS locus in infertile boarsConference 2014 Epiconcept "Epigenetics and Periconception Environment", Oct 2014, Vilamoura, Portugal. 72 p
Communication dans un congrès
hal-02739006v1
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Transcriptome diversity at multi- and single-cell levels in rabbit pluripotent stem cells11. Annual Meeting International Society for Stem Cell Research (ISSCR), International Society of Stem Cell Research (ISSCR). INT., Jun 2013, Boston, United States. 1 p
Communication dans un congrès
hal-01198231v1
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Analyse de la méthylation de l’ADN spermatique chez des verrats à qualité de semence dégradée44. Journées de la Recherche Porcine, Feb 2012, Paris, France
Communication dans un congrès
hal-02745264v1
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Effects of chromosomal abnormalities on sperm nuclear architecture18. International Chromosome Conference, Aug 2011, Manchester, United Kingdom. Abstract, 1 page
Communication dans un congrès
hal-01189510v1
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Molecular control of pluripotency and germ line competency in chicken embryonic stem cellsShanghai International Symposium on Stem Cell Research, Nov 2007, Shanghai, China. ⟨10.1038/cr.2008.196⟩
Communication dans un congrès
hal-02756866v1
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Gene regulatory networks inference in the pigs embryos from scRNAseq and scMulti-omicsISMB 2023, Jul 2023, Lyon, France
Poster de conférence
hal-04167509v1
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Impact of the ingestion of titanium dioxide nanoparticles via breast milk on the respiratory health of young rabbits.Journées de recherche respiratoire, Oct 2023, Tours, France
Poster de conférence
hal-04276856v1
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Deciphering the molecular network controlling the biology of the pig blastocyst and its cellular interactionsJournées Ouvertes en Biologie, Informatique et Mathématiques (JOBIM), Jul 2022, Rennes, France
Poster de conférence
hal-04176366v1
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Selection of cell lines for the functional validation of 3D genomic interactions by genome editing23. International Colloquium on Animal Cytogenetics and Genomics (23 ICACG), Jun 2018, Saint-Petersburg, Russia. Pensoft Publishers, Comparative Cytogenetics, 12 (3), 360 p., 2018, 23rd International Colloquium on Animal Cytogenetics and Genomics (23 ICACG)
Poster de conférence
hal-02734307v1
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Modifications ciblées des génomes: apports et impacts potentiels des nouvelles technologies pour les espèces aviaires12. Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, Apr 2017, Tours, France. ITAVI - Institut Technique de l'Aviculture, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, 12, 2017, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras
Poster de conférence
hal-01608254v1
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Long-non coding RNAs repertoires in liver and two T lymphocyte cell types in four livestock species36. Conference of the International Society for Animal Genetics (ISAG), Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book
Poster de conférence
hal-01621915v1
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Une nouvelle facette du génome de poule : les genes “longs non-codants"12. Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, Apr 2017, Tours, France. ITAVI - Institut Technique de l'Aviculture, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, 2017, Journées de la Recherche Avicole et des Palmipèdes à Foie Gras
Poster de conférence
hal-01605848v1
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Profiling the landscape of transcription, chromatin accessibility and chromosome conformation of cattle, pig, chicken and goat genomes [FAANG pilot project]36th International Society for Animal Genetics Conference, Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book
Poster de conférence
hal-01608449v1
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Integrative and differential analysis of transcriptomes and chromatin accessibility regions reveals regulatory mechanisms involved in pig immune and metabolic functions36th International Society for Animal Genetics Conference, Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book
Poster de conférence
hal-01603033v1
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Characterization of 3D genomic interactions in fetal pig muscle36th International Society for Animal Genetics Conference, Jul 2017, Dublin, Ireland. 2017, ISAG 2017 - Genomes to Phenomes - Abstract Book
Poster de conférence
hal-01608046v1
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Meiotic pairing and gene expression disturbance in germ cells from an infertile boar with a balanced reciprocal autosome-autosome translocation22. International Colloquium on Animal Cytogenetics and Genomics (ICACG), Jul 2016, Toulouse, France. INRA - INP - ENVT, Chromosome Research, 24 (S1), 116 p., 2016, Chromosome Research
Poster de conférence
hal-01886399v1
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Long-non coding RNAs repertoire in liver and adipose tissue in chickenXXIV International Plant & Animal Genome (Pag), Jan 2016, San Diego, United States. 2016
Poster de conférence
hal-02799305v1
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3D nuclear positioning of IGF2 alleles and trans interactions with imprinted genes in pig fetal cellsConference on Genome Architecture in Space and Time, Jun 2016, Trieste, Italy. 2016
Poster de conférence
hal-02794242v1
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Construction of whole genome interaction maps and study of correlation with gene expression level in fetal muscle cells22. International Colloquim on Animal Cytogenetics and Genomics (ICACG), Jul 2016, Toulouse, France. INRA - INP - ENVT, Chromosome Research, 24 (S1), 116 p., 2016, 22nd International Colloquim on Animal Cytogenetics and Genomics
Poster de conférence
hal-02743692v1
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Methylation levels at the GNAS locus is not associated with field fertility in Holstein bullsEpiconcept Workshop 2015 Periconception Environnement, Apr 2015, Dubrovnik, Croatia. COST Edition, 60 p., 2015, Epigenetics and Periconception Environment
Poster de conférence
hal-01194109v1
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Chromosomal causes of impaired reproductive performance in swinePoster de conférence hal-02794386v1 |
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Sampling tissue for FAANG: the example of cattle and chickens in FrancePoster de conférence hal-02801142v1 |
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DNA methylation analysis in sperm from infertile/subfertile boarsJacques Monod Conference, Sep 2014, Roscoff, France. 2013
Poster de conférence
hal-02803541v1
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Arcitecture nucléaire 3D et expression du génomeSéminaire du Departement de Génétique Animale, Apr 2014, Fréjus, France. 2013
Poster de conférence
hal-02810380v1
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Derivation of induced pluripotent stem cells from an infertile boar carrying a reciprocal translocationConference 2014 Epiconcept "Epigenetics and Periconception Environment", Oct 2014, Vilamoura, Portugal. COST Office European Cooperation in Science and Technology (Portugal), 2014, Proceedings of the EPICONCEPT Conference 2014 - COST Action FA1201
Poster de conférence
hal-02739129v1
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DNA methylation analysis in sperm from infertile/subfertile boars33. Conference of the International Society of Animal Genetics ISAG, Jul 2012, Cairns, Australia. 2012, 33rd Conference of the International Society for Animal Genetics
Poster de conférence
hal-02744773v1
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Inducing Sequential Cycles of Epithelial-Mesenchymal and Mesenchymal-Epithelial Transitions in Mammary Epithelial CellsThe Epithelial-to Mesenchymal Transition, pp.341-351, 2021, ⟨10.1007/978-1-0716-0779-4_26⟩
Chapitre d'ouvrage
hal-02950184v1
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In Situ Hybridization Analysis of Chick Embryos in Whole-Mount and Tissue SectionsAvian Embryology, 2nd edition, pp.169-185, 2008, ⟨10.1016/S0091-679X(08)00209-4⟩
Chapitre d'ouvrage
hal-02912726v1
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Housing conditions affect cell populations in adipose and muscle tissues of pigsAutre publication scientifique hal-04186114v1 |
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Cell specification and functional interactions in the pig blastocyst inferred from single cell transcriptomics2023
Pré-publication, Document de travail
hal-04143106v1
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Chronic circadian disruption modulates breast cancer cell stemness and their immune microenvironment to drive metastasis in mice2020
Pré-publication, Document de travail
hal-02954790v1
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Characterization of a Y-specific duplication/insertion of the anti-Mullerian hormone type II receptor gene based on a chromosome-scale genome assembly of yellow perch, Perca flavescens2019
Pré-publication, Document de travail
hal-02790966v1
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Livestock genome annotation: transcriptome and chromatin structure profiling in cattle, goat, chicken and pig2018
Pré-publication, Document de travail
hal-02791029v1
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IDENTIFICATION ET CARACTERISATION MOLECULAIRE D'UNE NOUVELLE FAMILLE DE GENES MARQUEURS DES CELLULES SOUCHES EMBRYONNAIRES DE POULETSciences du Vivant [q-bio]. Université Claude Bernard Lyon 1, 2003. Français. ⟨NNT : ⟩
Thèse
tel-02912760v1
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Caractérisation des propriétés souches des cellules de vertébrés : conservation et spécificité entre cellules embryonnaires et cellules tumoralesSciences du Vivant [q-bio]. Institut National Polytechnique (Toulouse), 2015
HDR
tel-02801190v1
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Mammalian Stem Cells: from isolation to applicationsMaster. Mammalian Stem Cells: from isolation to applications, Master Biomedical Engineering (BME) Université Paris Cité, France. 2023
Cours
hal-04454663v1
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Master 2 PRIAM 2023: Functional and Spatial annotation of livestocks' genomesMaster. Annotations fonctionnelles et spatiales des génomes des espèces d'élevage, INRAE Jouy en Josas, France. 2023, pp.97
Cours
hal-04424126v1
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