Ibai Valverde

Chargé de recherches CNRS
27
Documents

Domaines de recherche

Chimie organique

Compétences

Peptides Imagerie moléculaire Radiopharmacie

Publications

Publications

Image document

Convergent Synthesis of Template‐Assembled Synthetic G‐Quartets (TASQs) Used as Biomimetic and Multivalent G‐Quadruplex (G4) Ligands

Sandy Raevens , Cécile Desingle , Marc Pirrotta , Francesco Rota Sperti , Andréa Pieri et al.
Chemistry - A European Journal, 2025, pp.e03002. ⟨10.1002/chem.202503002⟩
Article dans une revue hal-05384162 v1
Image document

Photoactivatable, Biomimetic Ligand photoMultiTASQ Traps DNA/RNA G-Quadruplexes and Their Protein Binding Partners

Sandy Raevens , Yehuda Danino , Cécile Desingle , Francesco Rota Sperti , Marc Pirrotta et al.
ACS Bio & Med Chem Au, 2025, ⟨10.1021/acsbiomedchemau.5c00162⟩
Article dans une revue hal-05343353 v1
Image document

Fluorescence Detection of DNA/RNA G‐Quadruplexes (G4s) by Twice‐as‐Smart Ligands

Jiri Ledvinka , Francesco Rota Sperti , Gabor Paragi , Marc Pirrotta , Nicolas Chéron et al.
ChemMedChem, 2025, ⟨10.1002/cmdc.202400829⟩
Article dans une revue hal-05018355 v1
Image document

The multivalent G-quadruplex (G4)-ligands MultiTASQs allow for versatile click chemistry-based investigations

Francesco Rota Sperti , Jérémie Mitteaux , Joanna Zell , Angélique Pipier , Ibai E Valverde et al.
RSC Chemical Biology, 2023, 4 (7), pp.456-465. ⟨10.1039/D3CB00009E⟩
Article dans une revue hal-04154672 v1
Image document

Theranostics of Primary Prostate Cancer: beyond PSMA and GRP-R

Romain Schollhammer , Marie-Laure Quintyn Ranty , Henri de Clermont Gallerande , Florine Cavelier , Ibai E Valverde et al.
Cancers, 2023, 15 (8), pp.2345. ⟨10.3390/cancers15082345⟩
Article dans une revue hal-04075693 v1
Image document

Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs

Yilong Feng , Zexue He , Zhenyu Luo , Francesco Rota Sperti , Ibai E. Valverde et al.
iScience, 2023, 26 (6), pp.106846. ⟨10.1016/j.isci.2023.106846⟩
Article dans une revue hal-04110844 v1
Image document

A Modular One-Pot Strategy for the Synthesis of Heterobivalent Tracers

Thibaud Bailly , Sacha Bodin , Victor Goncalves , Franck Denat , Clément Morgat et al.
ACS Medicinal Chemistry Letters, In press, ⟨10.1021/acsmedchemlett.3c00057⟩
Article dans une revue hal-04087376 v1
Image document

Click-Chemistry-Based Biomimetic Ligands Efficiently Capture G-Quadruplexes <i>In Vitro</i> and Help Localize Them at DNA Damage Sites in Human Cells

Francesco Rota Sperti , Baptiste Dupouy , Jérémie Mitteaux , Angélique Pipier , Marc Pirrotta et al.
JACS Au, 2022, 2, pp.1588 - 1595. ⟨10.1021/jacsau.2c00082⟩
Article dans une revue hal-03738327 v1
Image document

Biomimetic, Smart, and Multivalent Ligands for G-Quadruplex Isolation and Bioorthogonal Imaging

Francesco Rota Sperti , Thibaut Charbonnier , Pauline Lejault , Joanna Zell , Claire Bernhard et al.
ACS Chemical Biology, 2021, 16 (5), pp.905 - 914. ⟨10.1021/acschembio.1c00111⟩
Article dans une revue hal-03321466 v1
Image document

1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs

Nathalie M. Grob , Roger Schibli , Martin Béhé , Ibai Valverde , Thomas L. Mindt
ACS Medicinal Chemistry Letters, In press, ⟨10.1021/acsmedchemlett.0c00636⟩
Article dans une revue hal-03178434 v1
Image document

Synthetic routes to novel fluorogenic pyronins and silicon analogs with far-red spectral properties and enhanced aqueous stability

Garance Dejouy , Kévin Renault , Ibai E. Valverde , Anthony Romieu
Dyes and Pigments, 2020, 180, pp.108496. ⟨10.1016/j.dyepig.2020.108496⟩
Article dans une revue hal-03007352 v1
Image document

Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity

Eirinaios Vrettos , Ibai E. Valverde , Alba Mascarin , Patrick Pallier , Linda Cerofolini et al.
Chemistry - A European Journal, 2020, 26 (47), pp.10690-10694. ⟨10.1002/chem.202000924⟩
Article dans une revue hal-03007010 v1
Image document

Synthesis and evaluation of zirconium-89 labelled and long-lived GLP-1 receptor agonists for PET imaging

Christian Borch Jacobsen , René Raavé , Marie Østergaard Pedersen , Pierre Adumeau , Mathieu Moreau et al.
Nuclear Medicine and Biology, 2020, 82-83, pp.49-56. ⟨10.1016/j.nucmedbio.2019.11.006⟩
Article dans une revue hal-03004102 v1
Image document

Fluorogenic Enzyme-Triggered Domino Reactions Producing Quinoxalin-2(1H)-one-based Heterocycles

Garance Dejouy , Kévin Renault , Quentin Bonnin , Arnaud Chevalier , Cédric Michaudet et al.
Organic Letters, 2020, 22 (16), pp.6494-6499. ⟨10.1021/acs.orglett.0c02287⟩
Article dans une revue hal-03006821 v1
Image document

Fluorogenic Enzyme-Triggered Domino Reactions Producing Quinoxalin-2(1 H)-one-based Heterocycles

Garance Dejouy , Kévin Renault , Quentin Bonnin , Arnaud Chevalier , Cédric Michaudet et al.
Organic Letters, 2020, 22 (16), pp.6494-6499. ⟨10.26434/chemrxiv.12613862.v1⟩
Article dans une revue hal-03016953 v1
Image document

The scope of application of macrocyclic polyamines beyond metal chelation

Pauline Lejault , Katerina Duskova , Claire Bernhard , Ibai E. Valverde , Anthony Romieu et al.
European Journal of Organic Chemistry, 2019, 2019 (36), pp.6146-6157. ⟨10.1002/ejoc.201900870⟩
Article dans une revue hal-02268694 v2
Image document

Quest for novel fluorogenic xanthene dyes: Synthesis, spectral properties and stability of 3-imino-3H-xanthen-6-amine (pyronin) and its silicon analog

Anthony Romieu , Garance Dejouy , Ibai Valverde
Tetrahedron Letters, 2018, 59 (52), pp.4574-4581. ⟨10.1016/j.tetlet.2018.11.031⟩
Article dans une revue hal-02168864 v1
Image document

Synthesis, stability and spectral behavior of fluorogenic sulfone-pyronin and sulfone-rosamine dyes

Garance Dejouy , Myriam Laly , Ibai Valverde , Anthony Romieu
Dyes and Pigments, 2018, 159, pp.262-274. ⟨10.1016/j.dyepig.2018.06.026⟩
Article dans une revue hal-02168863 v1

Amide-to-triazole switch vs. in vivo NEP-inhibition approaches to promote radiopeptide targeting of GRPR-positive tumors

Theodosia Maina , Aikaterini Kaloudi , Ibai E. Valverde , Thomas L. Mindt , Berthold A. Nock
Nuclear Medicine and Biology, 2017, 52, pp.57 - 62. ⟨10.1016/j.nucmedbio.2017.06.001⟩
Article dans une revue hal-01562008 v1

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

Ibai E Valverde , Fabien Lecaille , Gilles Lalmanach , Vincent Aucagne , Agnès F Delmas
Angewandte Chemie International Edition, 2012, 51 (3), pp.718-22. ⟨10.1002/anie.201107222⟩
Article dans une revue istex hal-00726293 v1

Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications.

Vincent Aucagne , Ibai E Valverde , Philippe Marceau , Mathieu Galibert , Nabil Dendane et al.
Angewandte Chemie International Edition, 2012, 51 (45), pp.11320-4. ⟨10.1002/anie.201206428⟩
Article dans une revue istex hal-00748170 v1

Click a la carte: robust semi-orthogonal alkyne protecting groups for multiple successive azide/alkyne cycloadditions

Ibai E. Valverde , Agnès F. Delmas , Vincent Aucagne
Tetrahedron, 2009, 65 (36), pp.7597-7602. ⟨10.1016/j.tet.2009.06.093⟩
Article dans une revue istex hal-00525398 v1