Isabelle VILA

27
Documents

Publications

Publications

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The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling

Hanane Chamma , Soumyabrata Guha , Roger Junior Eloiflin , Adeline Augereau , Pierre Le Hars et al.
Nature Communications, 2025, 16 (1), pp.9827. ⟨10.1038/s41467-025-65713-z⟩
Article dans une revue hal-05361456 v1

The ability of SAMHD1-deficient monocytes to trigger the Type I IFN response depends on cGAS and mitochondrial DNA

Jesse Rabinowitz , Isabelle Vila , Charlotte Luchsinger , Cinzia Bertelli , Moritz Schüssler et al.
Journal of Biological Chemistry, 2025, 301 (8), pp.110430. ⟨10.1016/j.jbc.2025.110430⟩
Article dans une revue hal-05362503 v1
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The unexpected role of the STING protein in lipid metabolism

Isabelle K Vila , Nadine Laguette
Comptes Rendus. Biologies, 2023, 346, pp.29 - 33. ⟨10.5802/crbiol.110⟩
Article dans une revue hal-04241169 v1
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Harnessing the cooperation between DNA‐PK and cGAS in cancer therapies

Clara Taffoni , Moritz Schüssler , Isabelle K Vila , Nadine Laguette
Article dans une revue (article de synthèse) hal-04125754 v1
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Multiplexed targeted analysis of polyunsaturated fatty acids and oxylipins using liquid chromatography-tandem mass spectrometry

Evgenia Turtoi , Jérémy Jeudy , Gilles Valette , Christine Enjalbal , Isabelle K Vila et al.
STAR Protocols, 2023, 4 (3), pp.102226. ⟨10.1016/j.xpro.2023.102226⟩
Article dans une revue (article de synthèse) hal-04241222 v1
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Dietary restriction induces a sexually dimorphic type I interferon response in mice with gene-environment interactions

Dylan J Harney , Michelle Cielesh , Georgia E Roberts , Isabelle K Vila , Barney Viengkhou et al.
Cell Reports, 2023, 42 (6), pp.112559. ⟨10.1016/j.celrep.2023.112559⟩
Article dans une revue hal-04241406 v1
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DNA damage repair kinase DNA‐PK and cGAS synergize to induce cancer‐related inflammation in glioblastoma

Clara Taffoni , Johanna Marines , Hanane Chamma , Soumyabrata Guha , Mathilde Saccas et al.
EMBO Journal, 2023, 42 (7), pp.e111961. ⟨10.15252/embj.2022111961⟩
Article dans une revue hal-03923380 v1
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Protocol to induce and assess cGAS-STING pathway activation in vitro

Hanane Chamma , Soumyabrata Guha , Nadine Laguette , Isabelle Vila
STAR Protocols, 2022, 3 (2), pp.101384. ⟨10.1016/j.xpro.2022.101384⟩
Article dans une revue hal-03807593 v1
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Alternative pathways driven by STING: From innate immunity to lipid metabolism

Isabelle Vila , Soumyabrata Guha , Joanna Kalucka , David Olagnier , Nadine Laguette
Cytokine and Growth Factor Reviews, 2022, ⟨10.1016/j.cytogfr.2022.08.006⟩
Article dans une revue hal-03807587 v1
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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

Isabelle Vila , Hanane Chamma , Alizée Steer , Mathilde Saccas , Clara Taffoni et al.
Cell Metabolism, 2022, 34 (1), pp.125-139.e8. ⟨10.1016/j.cmet.2021.12.007⟩
Article dans une revue hal-03520564 v1
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Activation of STING in the pancreatic tumor microenvironment: a novel therapeutic opportunity

Hanane Chamma , Isabelle Vila , Clara Taffoni , Andrei Turtoi , Nadine Laguette
Cancer Letters, 2022, 538, pp.215694. ⟨10.1016/j.canlet.2022.215694⟩
Article dans une revue hal-03668657 v1
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Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes

Clara Taffoni , Alizée Steer , Johanna Marines , Hanane Chamma , Isabelle Vila et al.
Frontiers in Immunology, 2021, 12, pp.660560. ⟨10.3389/fimmu.2021.660560⟩
Article dans une revue hal-03380383 v2
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Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives

Isabelle K Vila , Maxence Fretaud , Dimitrios Vlachakis , Nadine Laguette , Christelle Langevin
Journal of Molecular Biology, 2020, 432 (20), pp.5529-5543. ⟨10.1016/j.jmb.2020.08.016⟩
Article dans une revue (article de synthèse) hal-02989107 v1

PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression

Mi Kyung Park , Yixin Yao , Weiya Xia , Stephanie Rebecca Setijono , Jae Hwan Kim et al.
Nature Communications, 2019, 10 (1), pp.636. ⟨10.1038/s41467-019-08481-x⟩
Article dans une revue hal-04765231 v1
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A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity

Isabelle K Vila , Mi Kyung Park , Stephanie Rebecca Setijono , Yixin Yao , Hyejin Kim et al.
JCI Insight, 2019, 4 (13), pp.e128269. ⟨10.1172/jci.insight.128269⟩
Article dans une revue hal-04793048 v1

A new duet in cancer biology: AMPK the typical and UBE2O the atypical

Isabelle Vila , Su Jung Song , Min Sup Song
Molecular & Cellular Oncology, 2017, 4 (3), pp.e1304846. ⟨10.1080/23723556.2017.1304846⟩
Article dans une revue hal-04765241 v1

A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy

Isabelle Vila , Yixin Yao , Goeun Kim , Weiya Xia , Hyejin Kim et al.
Cancer Cell, 2017, 31 (2), pp.208-224. ⟨10.1016/j.ccell.2017.01.003⟩
Article dans une revue hal-04765198 v1

Long-term PGC1β overexpression leads to apoptosis, autophagy and muscle wasting

Danesh Sopariwala , Vikas Yadav , Pierre-Marie Badin , Neah Likhite , Megha Sheth et al.
Scientific Reports, 2017, 7 (1), pp.10237. ⟨10.1038/s41598-017-10238-9⟩
Article dans une revue hal-04765235 v1

Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice

Pierre-Marie Badin , Isabelle Vila , Danesh Sopariwala , Vikas Yadav , Sabina Lorca et al.
Scientific Reports, 2016, 6 (1), pp.26442. ⟨10.1038/srep26442⟩
Article dans une revue hal-04765192 v1

Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes

Marine Coué , Pierre-Marie Badin , Isabelle Vila , Claire Laurens , Katie Louche et al.
Diabetes, 2015, 64 (12), pp.4033-4045. ⟨10.2337/db15-0305⟩
Article dans une revue hal-05204309 v1
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Immune cell Toll-like receptor 4 mediates the development of obesity- and endotoxemia-associated adipose tissue fibrosis.

Isabelle K Vila , Pierre-Marie Badin , Marie-Adeline Marques , Laurent Monbrun , Corinne Lefort et al.
Plant Cell Reports, 2014, 7 (4), pp.1116-29. ⟨10.1016/j.celrep.2014.03.062⟩
Article dans une revue inserm-00991860 v1

High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle.

Pierre-Marie Badin , Isabelle K. Vila , Katie Louche , Aline Mairal , Marie-Adeline Marques et al.
Endocrinology, 2013, 154 (4), pp.1444-53. ⟨10.1210/en.2012-2029⟩
Article dans une revue inserm-00841051 v1
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Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.

Amandine Girousse , Geneviève Tavernier , Carine Valle , Cedric Moro , Niklas Mejhert et al.
PLoS Biology, 2013, 11 (2), pp.e1001485. ⟨10.1371/journal.pbio.1001485⟩
Article dans une revue inserm-00841328 v1