jean-Christophe Andrau

51
Documents

Publications

Publications

Targeting Transcription-Replication Conflicts using G-quadruplexes stabilizers in Multiple Myeloma

Laure Dutrieux , Sara Ovejero , Antoine Guillemin , Leriem Zellagui , Elke de Bruyne et al.
Blood Neoplasia, In press, pp.100072. ⟨10.1016/j.bneo.2025.100072⟩
Article dans une revue lirmm-04919719 v1

Abnormal Immune Profile in Individuals with Kabuki Syndrome

Margot Comel , Norma Saad , Debapratim Sil , Florence Apparailly , Marjolaine Willems et al.
Journal of Clinical Immunology, 2024, 45 (1), pp.7. ⟨10.1007/s10875-024-01796-5⟩
Article dans une revue hal-04913847 v1
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Comprehensive mapping of genetic variation at Epromoters reveals pleiotropic association with multiple disease traits

Jing Wan , Antoinette van Ouwerkerk , Jean-Christophe Mouren , Carla Heredia , Lydie Pradel et al.
Nucleic Acids Research, 2024, ⟨10.1093/nar/gkae1270⟩
Article dans une revue hal-04882272 v1
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G-quadruplex forming motifs in the promoter region of the B-MYB proto-oncogene

André Miranda , Anne Cucchiarini , Cyril Esnault , Jean-Christophe Andrau , Paula Oliveira et al.
International Journal of Biological Macromolecules, 2024, 270, pp.132244. ⟨10.1016/j.ijbiomac.2024.132244⟩
Article dans une revue hal-04753347 v1
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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions

Cyril Esnault , Talha Magat , Amal Zine El Aabidine , Encar Garcia-Oliver , Anne Cucchiarini et al.
Nature Genetics, 2023, 55 (8), pp.1359-1369. ⟨10.1038/s41588-023-01437-4⟩
Article dans une revue hal-04793061 v1
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RNA polymerase II CTD is dispensable for transcription and required for termination in human cells

Yousra Yahia , Alexia Pigeot , Amal Zine El Aabidine , Nilay Shah , Nezih Karasu et al.
EMBO Reports, 2023, 24 (9), pp.e56150. ⟨10.15252/embr.202256150⟩
Article dans une revue hal-04285692 v1
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The control of transcriptional memory by stable mitotic bookmarking

Maëlle Bellec , Jérémy Dufourt , George Hunt , Hélène Lenden-Hasse , Antonio Trullo et al.
Nature Communications, 2022, 13 (1), pp.1176. ⟨10.1038/s41467-022-28855-y⟩
Article dans une revue hal-03858303 v1
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Notch-dependent and -independent functions of transcription factor RBPJ

Tobias Friedrich , Francesca Ferrante , Léo Pioger , Andrea Nist , Thorsten Stiewe et al.
Nucleic Acids Research, 2022, 50 (14), pp.7925-7937. ⟨10.1093/nar/gkac601⟩
Article dans une revue hal-03852469 v1
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Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting

Katjana Tantale , Encar Garcia-Oliver , Marie-Cécile Robert , Adèle L’hostis , Yueyuxiao Yang et al.
Nature Communications, 2021, 12 (1), pp.4503. ⟨10.1038/s41467-021-24462-5⟩
Article dans une revue hal-03382893 v1
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Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers

Fabienne Bejjani , Claire Tolza , Mathias Boulanger , Damien Downes , Raphaël Romero et al.
Nucleic Acids Research, 2021, 49 (5), pp.2488-2508. ⟨10.1093/nar/gkab053⟩
Article dans une revue hal-03253453 v1
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GOLT1B Activation in Hepatitis C Virus-Infected Hepatocytes Links ER Trafficking and Viral Replication

Jacqueline Butterworth , Damien Gregoire , Marion Peter , Armando Andres Roca Suarez , Guillaume Desandré et al.
Pathogens, 2021, 11, ⟨10.3390/pathogens11010046⟩
Article dans une revue hal-03541060 v1

Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders

Erfan Aref-Eshghi , Jennifer Kerkhof , Victor Pedro , Mouna Barat-Houari , Nathalie Ruiz-Pallares et al.
American Journal of Human Genetics, 2020, 106 (3), pp.356-370. ⟨10.1016/j.ajhg.2020.01.019⟩
Article dans une revue hal-02538107 v1
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Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene

Jaafar Alomairi , Anne Molitor , Nori Sadouni , Saadat Hussain , Magali Torres et al.
PLoS ONE, 2020, 15 (5), pp.e0233191. ⟨10.1371/journal.pone.0233191⟩
Article dans une revue hal-02773600 v1
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Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation

Muhammad Ahmad Maqbool , Léo Pioger , Amal Zine El Aabidine , Nezih Karasu , Anne Marie Molitor et al.
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩
Article dans une revue hal-03015018 v1
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Immunopathological manifestations in Kabuki syndrome: a registry study of 177 individuals

Henri Margot , Guilaine Boursier , Claire Duflos , Elodie Sanchez , Jeanne Amiel et al.
Genetics in Medicine, 2020, 22 (1), pp.181-188. ⟨10.1038/s41436-019-0623-x⟩
Article dans une revue hal-02268419 v1
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Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation

Ulf Gehrmann , Marianne Burbage , Elina Zueva , Christel Goudot , Cyril Esnault et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩
Article dans une revue hal-02369616 v1
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MIR sequences recruit zinc finger protein ZNF768 to expressed genes

Michaela Rohrmoser , Michael Kluge , Yousra Yahia , Anita Gruber-Eber , Muhammad Ahmad Maqbool et al.
Nucleic Acids Research, 2019, 47 (2), pp.700-715. ⟨10.1093/nar/gky1148⟩
Article dans une revue hal-04918168 v1
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The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection

Tania Sultana , Dominic van Essen , Oliver Siol , Marc Bailly-Bechet , Claude Philippe et al.
Molecular Cell, 2019, 74 (3), pp.555-570.e7. ⟨10.1016/j.molcel.2019.02.036⟩
Article dans une revue hal-02401618 v1
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Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity

Myriam Koubi , Mathilde Poplineau , Julien Vernerey , Lia N 'Guyen , Guillaume Tiberi et al.
Nucleic Acids Research, 2018, 46 (7), pp.3339-3350. ⟨10.1093/nar/gky080⟩
Article dans une revue hal-01765664 v1

Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals.

Nilay Shah , Muhammad Ahmad Maqbool , Yousra Yahia , Amal Zine El Aabidine , Cyril Esnault et al.
Molecular Cell, 2018, 69 (1), pp.48-61.e6. ⟨10.1016/j.molcel.2017.12.009⟩
Article dans une revue hal-03022268 v1
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ARS2 is a general suppressor of pervasive transcription

Claudia Iasillo , Manfred Schmid , Yousra Yahia , Muhammad A Maqbool , Nicolas Descostes et al.
Nucleic Acids Research, 2017, 45 (17), pp.10229-10241. ⟨10.1093/nar/gkx647⟩
Article dans une revue hal-02343528 v1
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A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development

I. Screpanti , E. Serfling , A. K. Patra , S. Klein-Hessling , R. Rudolf et al.
Nature Communications, 2016, 7, pp.11841. ⟨10.1038/ncomms11841⟩
Article dans une revue hal-02187331 v1

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells

Erinn L. Soucie , Ziming Weng , Laufey Geirsdottir , Kaaweh Molawi , Julien Maurizio et al.
Science, 2016, 351 (6274), pp.680-U123. ⟨10.1126/science.aad5510⟩
Article dans une revue hal-01438535 v1
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Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation

Pierre Cauchy , Muhammad A. Maqbool , Joaquin Zacarias-Cabeza , Laurent Vanhille , Frederic Koch et al.
Nucleic Acids Research, 2016, 44 (8), pp.3567-3585. ⟨10.1093/nar/gkv1475⟩
Article dans une revue hal-01438545 v1

Pasha: a versatile R package for piling chromatin HTS data

Romain Fenouil , Nicolas Descostes , Lionel Spinelli , Frederic Koch , Muhammad Ahmad Maqbool et al.
Bioinformatics, 2016, 32 (16), pp.2528 - 2530. ⟨10.1093/bioinformatics/btw206⟩
Article dans une revue hal-01407393 v1
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The chromatin environment shapes DNA replication origin organization and defines origin classes

Christelle Cayrou , Benoit Ballester , Isabelle Peiffer , Romain Fenouil , Philippe Coulombe et al.
Genome Research, 2015, 25 (12), pp.1873-1885. ⟨10.1101/gr.192799.115⟩
Article dans une revue hal-03101863 v1
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Site- and allele-specific polycomb dysregulation in T-cell leukaemia

Jean-Marc Navarro , Aurore Touzart , Lydie Pradel , Marie Loosveld , Myriam Koubi et al.
Nature Communications, 2015, 6 (1), pp.6094. ⟨10.1038/ncomms7094⟩
Article dans une revue hal-01612097 v1
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High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq

Laurent Vanhille , Aurélien Griffon , Muhammad Ahmad Maqbool , Joaquin Zacarias-Cabeza , Lan T.M. Dao et al.
Nature Communications, 2015, 6, pp.6905. ⟨10.1038/ncomms7905⟩
Article dans une revue hal-01614948 v1

Transcription-Dependent Generation of a Specialized Chromatin Structure at the TCRβ Locus

Joaquin Zacarias-Cabeza , Mohamed Belhocine , Laurent Vanhille , Pierre Cauchy , Frederic Koch et al.
Journal of Immunology, 2015, 194 (7), pp.3432--3443. ⟨10.4049/jimmunol.1400789⟩
Article dans une revue hal-01614946 v1
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Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

Nicolas Descostes , Martin Heidemann , Lionel Spinelli , Roland Schüller , Muhammad Ahmad Maqbool et al.
Article dans une revue hal-01431911 v1

Architecture and expression of the nfatc1 gene in lymphocytes

R. Rudolf , R. Busch , A. K. Patra , K. Muhammad , A. Avots et al.
Frontiers in Immunology, 2014, 5, pp.21. ⟨10.3389/fimmu.2014.00021⟩
Article dans une revue hal-02191590 v1
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Divergent transcription is associated with promoters of transcriptional regulators.

Cyrille Lepoivre , Mohamed Belhocine , Aurélie Bergon , Aurélien Griffon , Miriam Yammine et al.
BMC Genomics, 2013, 14 (1), pp.914. ⟨10.1186/1471-2164-14-914⟩
Article dans une revue inserm-00924629 v1

Editorial for “Diversity of the non-coding transcriptomes revealed by RNA-seq technologies”

Antonin Morillon , Jean-Christophe Andrau
Methods, 2013, 63 (1), pp.1-2. ⟨10.1016/j.ymeth.2013.08.030⟩
Article dans une revue istex hal-02349843 v1

Editorial for "Diversity of the non-coding transcriptomes revealed by RNA-seq technologies

A. Morillon , J. C. Andrau
Methods, 2013, 63 (1), pp.1--2. ⟨10.1016/j.ymeth.2013.08.030⟩
Article dans une revue istex hal-02191629 v1
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Divergent transcription is associated with promoters of transcriptional regulators

C. Lepoivre , M. Belhocine , A. Bergon , A. Griffon , M. Yammine et al.
BMC Genomics, 2013, 14, pp.914. ⟨10.1186/1471-2164-14-914⟩
Article dans une revue hal-02192888 v1

An update on recent methods applied for deciphering the diversity of the noncoding RNA genome structure and function

S. Spicuglia , M. A. Maqbool , Denis Puthier , J. C. Andrau
Methods, 2013, 63 (1), pp.3--17. ⟨10.1016/j.ymeth.2013.04.003⟩
Article dans une revue hal-01595815 v1

Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation

C. Hintermair , M. Heidemann , F. Koch , N. Descostes , M. Gut et al.
EMBO Journal, 2012, 31 (12), pp.2784--97. ⟨10.1038/emboj.2012.123⟩
Article dans une revue hal-02193058 v1

CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters

R. Fenouil , P. Cauchy , F. Koch , N. Descostes , J. Z. Cabeza et al.
Genome Research, 2012, 22 (12), pp.2399--2408. ⟨10.1101/gr.138776.112⟩
Article dans une revue hal-01614960 v1
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Argonaute proteins couple chromatin silencing to alternative splicing

Maya Ameyar-Zazoua , Christophe Rachez , Mouloud Souidi , Philippe Robin , Lauriane Fritsch et al.
Nature Structural and Molecular Biology, 2012, 19 (10), pp.998 - 1004. ⟨10.1038/nsmb.2373⟩
Article dans une revue istex pasteur-01393429 v1

Noncoding transcription at enhancers: general principles and functional models

G. Natoli , J. C. Andrau
Annual Review of Genetics, 2012, 46, pp.1--19. ⟨10.1146/annurev-genet-110711-155459⟩
Article dans une revue hal-02193070 v1

Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36.

Sérgio Fernandes de Almeida , Ana Rita Grosso , Frederic Koch , Romain Fenouil , Sílvia Carvalho et al.
Nature Structural and Molecular Biology, 2011, 18 (9), pp.977-83. ⟨10.1038/nsmb.2123⟩
Article dans une revue istex hal-00667731 v1

Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters.

Frederic Koch , Romain Fenouil , Marta Gut , Pierre Cauchy , Thomas K Albert et al.
Nature Structural and Molecular Biology, 2011, 2 (4), epub ahead of print. ⟨10.1038/nsmb.2085⟩
Article dans une revue istex hal-00609674 v1

H3K4 tri-methylation provides an epigenetic signature of active enhancers: Epigenetic signature of active enhancers

Aleksandra Pekowska , Touati Benoukraf , Joaquin Zacarias-Cabeza , Mohamed Belhocine , Frederic Koch et al.
EMBO Journal, 2011, 30 (20), pp.4198--4210. ⟨10.1038/emboj.2011.295⟩
Article dans une revue hal-01614961 v1

Initiating RNA polymerase II and TIPs as hallmarks of enhancer activity and tissue-specificity

F. Koch , J. C. Andrau
Transcription, 2011, 2 (6), pp.263--8. ⟨10.4161/trns.2.6.18747⟩
Article dans une revue hal-02193318 v1

CoCAS: a ChIP-on-chip analysis suite.

Touati Benoukraf , Pierre Cauchy , Romain Fenouil , Adrien Jeanniard , Frederic Koch et al.
Bioinformatics, 2009, 25 (7), pp.954-5. ⟨10.1093/bioinformatics/btp075⟩
Article dans une revue hal-00408403 v1

The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation

A. Aslam , S. Mittal , F. Koch , J. C. Andrau , G. S. Winkler
Molecular Biology of the Cell, 2009, 20 (17), pp.3840--50. ⟨10.1091/mbc.E09-02-0146⟩
Article dans une revue hal-02194079 v1

Genome-wide RNA polymerase II: not genes only!

Frederic Koch , Frederic Jourquin , Pierre Ferrier , Jean-Christophe Andrau
Trends in Biochemical Sciences, 2008, 33 (6), pp.265-273. ⟨10.1016/j.tibs.2008.04.006⟩
Article dans une revue istex hal-00294059 v1