Jean-Christophe Gimel

71
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Publications

Publications

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Design and characterization of propofol lipid nanocapsules: proof of concept for hospital preparation

Emilie Tireau , Marie Bonnin , Guillaume Lefebvre , Louise Stinat , Etienne Chevremont et al.

International Journal of Pharmaceutics, 2026, 692, pp.126640. ⟨10.1016/j.ijpharm.2026.126640⟩

Article dans une revue hal-05491490v1
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Distribution of amiodarone between lipid nanocapsules and residual micelles: Tangential flow filtration as a purification method and its impact on cytotoxicity

Jaspe Chen , Sophie Tamareille , Etienne Chèvremont , Jean-Christophe Gimel , Brice Calvignac et al.

International Journal of Pharmaceutics, 2025, 677, pp.125651. ⟨10.1016/j.ijpharm.2025.125651⟩

Article dans une revue hal-05353785v1
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Evidence of residual micellar structures in a lipid nanocapsule dispersion. A multi-technique approach

Emilie Roger , Florence Franconi , Tran Anh Thu Do , Carl Simonsson , Benjamin Siegler et al.

Journal of Controlled Release, 2023, 364, pp.700-717. ⟨10.1016/j.jconrel.2023.10.054⟩

Article dans une revue hal-04295223v1
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Reactive precipitation of vaterite calcium carbonate microspheres in supercritical carbon dioxide-water dispersion by microfluidics

Pierre Legout , Guillaume Lefebvre , Marie Bonnin , Jean Christophe Gimel , L. Benyahia et al.

Journal of Supercritical Fluids, 2022, 188, pp.105678. ⟨10.1016/j.supflu.2022.105678⟩

Article dans une revue hal-03737443v1
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Galenic Lab-on-a-Chip concept for lipid nanocapsules production

Nicolas Rolley , Marie Bonnin , Guillaume Lefebvre , Sylvain Verron , Sylwester Bargiel et al.

Nanoscale, 2021, 13, pp.11899 - 11912. ⟨10.1039/d1nr00879j⟩

Article dans une revue hal-03276290v1
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NMR diffusometry: A new perspective for nanomedicine exploration

Florence Franconi , Laurent Lemaire , Jean-Christophe Gimel , Samuel Bonnet , Patrick Saulnier

Journal of Controlled Release, 2021, ⟨10.1016/j.jconrel.2021.07.025⟩

Article dans une revue hal-03291966v1
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Synthesis of PDMS- b -POEGMA Diblock Copolymers and Their Application for the Thermoresponsive Stabilization of Water-Supercritical Carbon Dioxide Emulsions

Pierre Legout , Guillaume Lefebvre , Marie Bonnin , Jean-Christophe Gimel , Lazhar Benyahia et al.

Langmuir, 2020, 36 (43), pp.12922−12932. ⟨10.1021/acs.langmuir.0c02194⟩

Article dans une revue hal-02973293v1
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Modulation of protein release from penta-block copolymer microspheres

Minh-Quan Le , Jean-Christophe Gimel , Xavier Garric , Thao-Quyen Nguyen-Pham , Cédric Paniagua et al.

European Journal of Pharmaceutics and Biopharmaceutics, 2020, 152, pp.175-182. ⟨10.1016/j.ejpb.2020.05.009⟩

Article dans une revue hal-02612734v1
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Importance of Combining Advanced Particle Size Analysis Techniques To Characterize Cell-Penetrating Peptide–Ferrocifen Self-Assemblies

Léna Guyon , Elise Lepeltier , Jean-Christophe Gimel , Brice Calvignac , Florence Franconi et al.

Journal of Physical Chemistry Letters, 2019, 10 (21), pp.6613-6620. ⟨10.1021/acs.jpclett.9b01493⟩

Article dans une revue hal-02319158v1

NMR diffusometry data sampling optimization for mixture analysis

Florence Franconi , Laurent Lemaire , Benjamin Siegler , Jean-Christophe Gimel , Patrick Saulnier

Journal of Pharmaceutical and Biomedical Analysis, 2018, 148, pp.156-162. ⟨10.1016/j.jpba.2017.09.028⟩

Article dans une revue hal-02339344v1

A multi-scale approach for percolation transition and its application to cement setting

Achutha Prabhu , Jean-Christophe Gimel , Andrés Ayuela , Silvia Arrese-Igor , Juan Gaitero et al.

Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-33918-6⟩

Article dans une revue hal-02339234v1

Spontaneous nano-emulsification: Process optimization and modeling for the prediction of the nanoemulsion’s size and polydispersity

Guillaume Lefebvre , Jérémie Riou , Guillaume Bastiat , Emilie Roger , Kristen Frombach et al.

International Journal of Pharmaceutics, 2017, 534 (1-2), pp.220-228. ⟨10.1016/j.ijpharm.2017.10.017⟩

Article dans une revue hal-02341597v1
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Lipid nanocapsules maintain full integrity after crossing a human intestinal epithelium model

Emilie Roger , Jean Christophe Gimel , Conor Bensley , Andrey S Klymchenko , Jean Pierre Benoit

Journal of Controlled Release, 2017, 253, pp.11-18. ⟨10.1016/j.jconrel.2017.03.005⟩

Article dans une revue hal-03805634v1

How to design the surface of peptide-loaded nanoparticles for efficient oral bioavailability?

Hélène Malhaire , Jean-Christophe Gimel , Emilie Roger , Jean-Pierre Benoît , Frédéric Lagarce

Advanced Drug Delivery Reviews, 2016, pp.1-17. ⟨10.1016/j.addr.2016.03.011⟩

Article dans une revue hal-01392464v1

Brownian cluster dynamics with short range patchy interactions: Its application to polymers and step-growth polymerization

A. Prabhu , Sujin Babu , J. Dolado , Jean Christophe Gimel

The Journal of Chemical Physics, 2014, 141 (2), pp.024904. ⟨10.1063/1.4886585⟩

Article dans une revue hal-02351008v1

Nanoscale texture development of C-S-H gel: A computational model for nucleation and growth

R. González-Teresa , J. Dolado , A. Ayuela , Jean-Christophe Gimel

Applied Physics Letters, 2013, 103 (23), pp.234105. ⟨10.1063/1.4838396⟩

Article dans une revue hal-02565747v1

Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery

Anne-Claire Groo , Patrick Saulnier , Jean-Christophe Gimel , Julien Gravier , Caroline Ailhas et al.

International Journal of Nanomedicine, 2013, pp.4291. ⟨10.2147/IJN.S51837⟩

Article dans une revue hal-02565768v1

Self-diffusion of non-interacting hard spheres in particle gels

Jean-Christophe Gimel , Taco Nicolai

Journal of Physics: Condensed Matter, 2011, 23 (23), pp.234115. ⟨10.1088/0953-8984/23/23/234115⟩

Article dans une revue hal-02351020v1

Crystallization and dynamical arrest of attractive hard spheres

Sujin Babu , Jean-Christophe Gimel , Taco Nicolai

The Journal of Chemical Physics, 2009, 130, pp.064504. ⟨10.1063/1.3074310⟩

Article dans une revue hal-00379777v1

Diffusion limited cluster aggregation with irreversible slippery bonds

Sujin Babu , Jean-Christophe Gimel , Taco Nicolai

European Physical Journal E: Soft matter and biological physics, 2008, 27, pp.297-308. ⟨10.1140/epje/i2008-10381-8⟩

Article dans une revue istex hal-00338461v1

The influence of bond rigidity and cluster diffusion on the self-diffusion of hard spheres with square-well interaction

Sujin Babu , Jean-Christophe Gimel , Taco Nicolai , Cristiano de Michele

The Journal of Chemical Physics, 2008, 128, pp.204504. ⟨10.1063/1.2925686⟩

Article dans une revue hal-00338457v1

Tracer diffusion in colloidal gels

Sujin Babu , Jean-Christophe Gimel , Taco Nicolai

Journal of Physical Chemistry B, 2008, 112 (3), pp.743-748. ⟨10.1021/jp076342+⟩

Article dans une revue hal-00206247v1

Self diffusion of reversibly aggregating spheres

Sujin Babu , Jean-Christophe Gimel , Taco Nicolai

The Journal of Chemical Physics, 2007, 127, pp.054503. ⟨10.1063/1.2756838⟩

Article dans une revue hal-00180979v1

Phase separation and percolation of reversibly aggregating spheres with a square-well attraction potential.

Sujin Babu , Jean-Christophe Gimel , Taco Nicolai

The Journal of Chemical Physics, 2006, 125, pp.184512-1-10. ⟨10.1063/1.2378832⟩

Article dans une revue hal-00134530v1
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Flocculation and percolation in reversible cluster-cluster aggregation.

Sujin Babu , Manuel Rottereau , Taco Nicolai , Jean-Christophe Gimel , Dominique Durand

European Physical Journal E: Soft matter and biological physics, 2006, 19, pp.203-211. ⟨10.1140/epje/e2006-00022-7⟩

Article dans une revue istex hal-00020136v1
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Depletion from a hard wall induced by aggregation and gelation.

Manuel Rottereau , Taco Nicolai , Jean-Christophe Gimel

European Physical Journal E: Soft matter and biological physics, 2005, 18, pp.37-40. ⟨10.1140/epje/i2005-10028-4⟩

Article dans une revue istex hal-00015710v1
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Influence of the Brownian step size in off-lattice Monte-Carlo simulations of irreversible particle aggregation.

Manuel Rottereau , Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

European Physical Journal E: Soft matter and biological physics, 2005, 18, pp.15-19. ⟨10.1140/epje/i2005-10027-5⟩

Article dans une revue istex hal-00015713v1

Monte Carlo simulation of particle aggregation and gelation: II. Pair correlation function and structure factor.

Manuel Rottereau , Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

European Physical Journal E: Soft matter and biological physics, 2004, 15, pp.141-148. ⟨10.1140/epje/i2004-10045-9⟩

Article dans une revue istex hal-00020747v1

Monte Carlo simulation of particle aggregation and gelation: I. Growth, structure and size distribution of the clusters.

Manuel Rottereau , Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

European Physical Journal E: Soft matter and biological physics, 2004, 15, pp.133-140. ⟨10.1140/epje/i2004-10044-x⟩

Article dans une revue istex hal-00020746v1

3d Monte Carlo simulations of site-bond continuum percolation of spheres.

Manuel Rottereau , Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

European Physical Journal E: Soft matter and biological physics, 2003, 11, pp.61-64. ⟨10.1140/epje/i2003-10006-x⟩

Article dans une revue istex hal-00086915v1

Aggregation, gelation and phase separation of heat denatured globular proteins

Dominique Durand , Jean-Christophe Gimel , Taco Nicolai

Physica A: Statistical Mechanics and its Applications, 2002, 304 (1-2), pp.253-265. ⟨10.1016/S0378-4371(01)00514-3⟩

Article dans une revue istex hal-02565889v1

Relation between aggregation and phase separation: Three-dimensional Monte Carlo simulations

Jean Christophe Gimel , Taco Nicolai , Dominique Durand

Physical Review E , 2002, 66, pp.061405. ⟨10.1103/PhysRevE.66.061405⟩

Article dans une revue hal-02565879v1

Monte-Carlo simulation of transient gel formation and break-up during reversible aggregation

Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

European Physical Journal E: Soft matter and biological physics, 2001, 5 (4), pp.415-422. ⟨10.1007/s101890170048⟩

Article dans une revue istex hal-02565950v1

Size distribution of percolating clusters on cubic lattices

Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

Journal of Physics A: Mathematical and General (1975 - 2006), 2000, 33 (43), pp.7687-7697. ⟨10.1088/0305-4470/33/43/302⟩

Article dans une revue istex hal-02571441v1

A direct parallel implementation of the Hoshen–Kopelman algorithm for distributed memory architectures

J.M. Teuler , Jean-Christophe Gimel

Computer Physics Communications, 2000, 130 (1-2), pp.118-129. ⟨10.1016/S0010-4655(00)00046-1⟩

Article dans une revue istex hal-02565995v1

Crossing probabilities in one, two or three directions for percolation on a cubic lattice

Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

Journal of Physics A: Mathematical and General (1975 - 2006), 1999, 32 (48), pp.L515-L519. ⟨10.1088/0305-4470/32/48/102⟩

Article dans une revue istex hal-02571430v1

Structure and size distribution of percolating clusters. Comparison with gelling systems

Jean-Christophe Gimel , Taco Nicolai , Dominique Durand , Jean-Marie Teuler

The European Physical Journal B: Condensed Matter and Complex Systems, 1999, 12 (1), pp.91-97. ⟨10.1007/s100510050982⟩

Article dans une revue istex hal-02567997v1

SDS Micelles at High Ionic Strength. A Light Scattering, Neutron Scattering, Fluorescence Quenching, and CryoTEM Investigation

M. Almgren , Jean-Christophe Gimel , Ke Wang , G. Karlsson , K. Edwards et al.

Journal of Colloid and Interface Science, 1998, 202 (2), pp.222-231. ⟨10.1006/jcis.1998.5503⟩

Article dans une revue istex hal-02567982v1

Fractality of Globular Protein Aggregates: From the Molecular to the Microscopic Level

Pierre Aymard , Dominique Durand , Taco Nicolai , Jean-Christophe Gimel

Fractals, 1997, 05 (supp02), pp.23-43. ⟨10.1142/S0218348X97000814⟩

Article dans une revue hal-02566961v1
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Experimental evidence for a two-step process in the aggregation of β-lactoglobulin at pH 7

Pierre Aymard , Jean-Christophe Gimel , Taco Nicolai , Dominique Durand

Journal de Chimie Physique et de Physico-Chimie Biologique, 1996, 93, pp.987-997. ⟨10.1051/jcp/1996930987⟩

Article dans une revue istex hal-02566883v1
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Analysis of Relaxation Functions Characterized by a Broad Monomodal Relaxation Time Distribution

Taco Nicolai , Jean Gimel , Robert Johnsen

Journal de Physique II, 1996, 6 (5), pp.697-711. ⟨10.1051/jp2:1996206⟩

Article dans une revue istex jpa-00248328v1
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A light scattering investigation of the sodium dodecyl sulfate–lysozyme system

Jean-Christophe Gimel , Wyn Brown

The Journal of Chemical Physics, 1996, 104 (20), pp.8112-8117. ⟨10.1063/1.471496⟩

Article dans une revue hal-02566933v1

Transition between flocculation and percolation of a diffusion-limited cluster-cluster aggregation process using three-dimensional Monte Carlo simulation

Jean-Christophe Gimel , Dominique Durand , Taco Nicolai

Physical Review B: Condensed Matter and Materials Physics (1998-2015), 1995, 51 (17), pp.11348-11357. ⟨10.1103/PhysRevB.51.11348⟩

Article dans une revue hal-02566531v1
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Static structure factor of dilute solutions of polydisperse fractal aggregates

Taco Nicolai , Dominique Durand , Jean-Christophe Gimel

Physical Review B: Condensed Matter and Materials Physics (1998-2015), 1994, 50 (22), pp.16357-16363. ⟨10.1103/PhysRevB.50.16357⟩

Article dans une revue hal-02318707v1

Structure and distribution of aggregates formed after heat-induced denaturation of globular proteins

Jean-Christophe Gimel , Dominique Durand , Taco Nicolai

Macromolecules, 1994, 27 (2), pp.583-589. ⟨10.1021/ma00080a037⟩

Article dans une revue istex hal-02318708v1

Design et évaluation pré-clinique d'un dispositif microfluidique d’infusion pour la thérapie des tumeurs cérébrales

Laurent Lemaire , Mathieu Weitten , Gregory Hilairet , Isabelle Verdu , Florence Franconi et al.

17èmes journées du Cancéropôle Grand-Ouest. Vannes, Jun 2023, Vannes, France

Poster de conférence hal-04105790v1

Experimental evidence of residual micellar structures in lipid nanocapsules suspensions

Tran Anh Thu Do , Emilie Roger , Florence Franconi , Benjamin Siegler , Rodolphe Perrot et al.

SFnano, Dec 2022, Strasbourg, France.

Poster de conférence hal-03890468v1

Synthesis and characterization of cell-penetrating peptide-ferrocifen self-assemblies

Léna Guyon , Elise Lepeltier , Jean-Christophe Gimel , Brice Calvignac , Florence Franconi et al.

IUPAC, Jul 2019, Paris, France

Poster de conférence hal-02617358v1

Is dynamic light scattering a good method to characterize self-assemblies of cell penetrating peptide-ferrocifen conjugates?

Léna Guyon , Elise Lepeltier , Jean-Christophe Gimel , Brice Calvignac , Florence Franconi et al.

SF Nano, Dec 2019, Dijon, France

Poster de conférence hal-02617249v1

Fluid-poroelastic interface modelling for an implantable medical device: Application to brain tumours treatment

Julien Rolland , Alexei Lozinski , Jean-Christophe Gimel , Florence Franconi , Laurent Lemaire et al.

14ème journées d'étude des milieux poreux, 2018, Nantes, France. , 2018

Poster de conférence hal-02616013v1

Effect of process parameters on morphology and release profile of Penta-block PLGA-based Microspheres

Minh Quan Le , Jean Christophe Gimel , Xavier Garric , Marie-Claire Venier-Julienne

2nd European conference on pharmaceutics (APGI), 2017, Krakow, Poland

Poster de conférence hal-02631540v1

Aggregation of wheat prolamins: a computer simulation study

Achutha Prabhu , Denis Renard , Jean-Christophe Gimel

Journées Ecole Doctorale Matières, Molécules, Matériaux en Pays de la Loire 3MPL, Jun 2011, Le Mans, France. 2011

Poster de conférence hal-02802747v1

Aggregation of wheat prolamins: a computer simulation study

Achutha Prabhu , Denis Renard , Jean-Christophe Gimel

Journées Ecole Doctorale Matières, Molécules, Matériaux en Pays de la Loire 3MPL, Jun 2010, Nantes, France. 2010

Poster de conférence hal-02814739v1

Development of the Galenic Lab-on-a-chip and ​Therapy-on-a-chip concepts for drug formulation / delivery

Laurent Lemaire , Guillaume Brotons , Marie Bonnin , Guillaume Lefebvre , Florence Franconi et al.

Journées plenières du GDR MicroNanofluidique, Apr 2023, Lyon, France

Communication dans un congrès hal-04105812v1
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Précipitation réactive en milieu CO2 supercritique de microsphères nanostructurées de carbonate de calcium par procédé microfluidique

Pierre Legout , Guillaume Lefebvre , Marie Bonnin , Jean-Christophe Gimel , Lazhar Benyahia et al.

18ème Congrès de la Société Française de Génie des Procédés, SFGP, Nov 2022, Toulouse, France

Communication dans un congrès hal-04124139v1

Formulation of vancomycin nanocomplexes through a microfluidic process for the treatment of Clostridium Difficile infections

Sébastien Wang , Brice Calvignac , Guillaume Lefebvre , Camille Savary , Jean Christophe Gimel et al.

SFNano Annual Meeting 2021, SFNano, Dec 2021, Angers, France

Communication dans un congrès hal-03480264v1

Caractérisation de l'activité interfaciale et du comportement auto-associatif de copolymères à blocs amphiphiles : application à la formulation d'émulsions Eau/CO2 supercritique pour la précipitation réactive de CaCO3

Pierre Legout , Olivier Colombani , Guillaume Lefevbre , Marie Bonnin , Jean Christophe Gimel et al.

Congrès de la Société Française de Génie des Procédés, Oct 2019, Nantes, France

Communication dans un congrès hal-03472842v1

Nanoassemblies formed by polyarginine-ferrocifen conjugates for lung cancer treatment

Léna Guyon , Elise Lepeltier , Brice Calvignac , Nolwenn Lautram , Bénédicte Lelièvre et al.

SF Nano, Dec 2018, Montpellier, France

Communication dans un congrès hal-02617897v1

Fluid-poroelastic interface modelling for an implantable medical device: Application to brain tumours treatment

Julien Rolland , Alexei Lozinski , Brice Calvignac , Jean-Christophe Gimel , Florence Franconi et al.

3rd Mathematical Biology Modelling days of Besançon, 2018, Besançon, France

Communication dans un congrès hal-02616012v1

Effect of Nano Seeds in C-S-H Gel Formation: Simulation Study from the Colloidal Point of View

Achutha Prabhu , Jean-Christophe Gimel , A. Ayuela , Jorge S. Dolado

CONCREEP 10, 2015, Vienne, Austria. ⟨10.1061/9780784479346.104⟩

Communication dans un congrès hal-01393852v1

Assessment of the diffusion coefficient of nanocarriers with the fluorescence recovery technique in gastrointestinal mucus

Alison Dénarnaud , Jérémie Riou , Rodolphe Perrot , Emilie Roger , Frédéric Lagarce et al.

Crossing Biological Barriers - Advances in Nanocarriers Design for Targeted Drug Delivery, 2015, Dresde, Germany

Communication dans un congrès hal-02615956v1

Particle diffusion in colloid gels

Dominique Durand , Gireeshkumar Balakrishnan Nair , Sujin-B. Babu , Taco Nicolaï , Jean-Christophe Gimel

3rd International Conference on Polymer Processing and Characterization, 2014, Kottayam, Inde

Communication dans un congrès hal-03180814v1

Quantitative analysis of protein gel structure by confocal laser scanning microscopy

Komla Ako , Lydiane Bécu , Taco Nicolai , Jean-Christophe Gimel , Dominique Durand

14th European Microscopy Congress (ECM 2008), Sep 2008, Aachen, Germany. pp.757-758, ⟨10.1007/978-3-540-85226-1_379⟩

Communication dans un congrès istex hal-00338459v1