Jenny VALLADEAU-GUILEMOND

49
Documents

Publications

Publications

IntegrAlign: a comprehensive tool for multi-immunofluorescence panel integration through image alignment

Leo Hermet , Leo Laoubi , Martial Scavino , Anne-Claire Doffin , Alexia Gazeu et al.
Bioinformatics, 2025, 41 (11), ⟨10.1093/bioinformatics/btaf567⟩
Article dans une revue hal-05345710 v1

IntegrAlign: A comprehensive tool for multi-immunofluorescence panel integration through image alignment

Leo Hermet , Leo Laoubi , Martial Scavino , Anne-Claire Doffin , Alexia Gazeu et al.
Bioinformatics, In press, ⟨10.1101/2025.04.10.648082⟩
Article dans une revue hal-05288547 v1
Image document

Type III interferon primes pDCs for TLR7 activation and antagonizes immune suppression mediated by TGF-β and PGE2

Candice Sakref , Alexis Saby , Céline Rodriguez , Maude Ardin , Lyvia Moudombi et al.
Nature Communications, 2025, 16 (1), pp.3045. ⟨10.1038/s41467-025-58220-8⟩
Article dans une revue hal-05021654 v1

HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer

Paola Bonaventura , Audrey Page , Olivier Tabone , Yann Estornes , Virginie Mutez et al.
Journal for Immunotherapy of Cancer, 2025, 13 (8), pp.e010099. ⟨10.1136/jitc-2024-010099⟩
Article dans une revue hal-05288554 v1

The spatial organization of cDC1 with CD8+ T cells is critical for the response to immune checkpoint inhibitors in melanoma patients

Elisa Gobbini , Margaux Hubert , Anne-Claire Doffin , Anais Eberhardt , Léo Hermet et al.
Cancer Immunology Research, 2025, ⟨10.1158/2326-6066.CIR-24-0421⟩
Article dans une revue hal-04879746 v1
Image document

Development of NK cell-based cancer immunotherapies through receptor engineering

Audrey Page , Nicolas Chuvin , Jenny Valladeau-Guilemond , Stéphane Depil
Cellular and molecular immunology, 2024, 21, pp.315 - 331. ⟨10.1038/s41423-024-01145-x⟩
Article dans une revue (article de synthèse) hal-04567993 v1
Image document

Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods

Felix Bayerl , David A Bejarano , Giulia Bertacchi , Anne‐claire Doffin , Elisa Gobbini et al.
European Journal of Immunology, 2023, 53 (11), pp.2249923. ⟨10.1002/eji.202249923⟩
Article dans une revue hal-04477856 v1

Phenotypes and Functions of Human Dendritic Cell Subsets in the Tumor Microenvironment

Candice Sakref , Nathalie Bendriss-Vermare , Jenny Valladeau-Guilemond
Methods in Molecular Biology, 2023, Methods in Molecular Biology, 2618, pp.17-35. ⟨10.1007/978-1-0716-2938-3_2⟩
Article dans une revue hal-04480198 v1

Isolation and Identification of Dendritic Cell Subsets from Human and Mouse Tumors

Yamila Rocca , Aurélien Voissière , Jenny Valladeau-Guilemond , Nathalie Bendriss-Vermare
Methods in Molecular Biology, 2023, Methods in Molecular Biology, 2618, pp.187-197. ⟨10.1007/978-1-0716-2938-3_14⟩
Article dans une revue hal-04480202 v1
Image document

Unique CLR expression patterns on circulating and tumor-infiltrating DC subsets correlated with clinical outcome in melanoma patients

Eleonora Sosa Cuevas , Jenny Valladeau-Guilemond , Stephane Mouret , Benoît Roubinet , Florence de Fraipont et al.
Frontiers in Immunology, 2022, 13, pp.1040600. ⟨10.3389/fimmu.2022.1040600⟩
Article dans une revue hal-04098615 v1

Direct T-cell Presentation by cDC1: The Key Feature for Cancer Vaccine Success?

Margaux Hubert , Christophe Caux , Jenny Valladeau-Guilemond
Cancer Immunology Research, 2022, 10 (8), pp.918-918. ⟨10.1158/2326-6066.CIR-22-0473⟩
Article dans une revue hal-03783998 v1
Image document

Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy

Paola Bonaventura , Vincent Alcazer , Virginie Mutez , Laurie Tonon , Juliette Martin et al.
Science Advances , 2022, 8 (4), ⟨10.1126/sciadv.abj3671⟩
Article dans une revue hal-03552937 v1
Image document

Diversification of circulating and tumor‐infiltrating plasmacytoid DCs towards the P3 (CD80 + PDL1 − )‐pDC subset negatively correlated with clinical outcomes in melanoma patients

Eleonora Sosa Cuevas , Nathalie Bendriss-Vermare , Stephane Mouret , Florence de Fraipont , Julie Charles et al.
Clinical and Translational Immunology, 2022, 11 (5), pp.e1382. ⟨10.1002/cti2.1382⟩
Article dans une revue hal-03783977 v1
Image document

Type 1 conventional dendritic cells and interferons are required for spontaneous CD4 + and CD8 + T‐cell protective responses to breast cancer

Raphaël Mattiuz , Carine Brousse , Marc Ambrosini , Jean‐charles Cancel , Gilles Bessou et al.
Clinical and Translational Immunology, 2021, 10, ⟨10.1002/cti2.1305⟩
Article dans une revue hal-03329001 v1
Image document

Expression of TAM-R in Human Immune Cells and Unique Regulatory Function of MerTK in IL-10 Production by Tolerogenic DC

Paul Giroud , Sarah Renaudineau , Laura Gudefin , Alexandre Calcei , Thierry Menguy et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.564133⟩
Article dans une revue hal-03769650 v1
Image document

Hepatitis B virus exploits C‐type lectin receptors to hijack cDC1s, cDC2s and pDCs

Laurissa Ouaguia , Tania Dufeu-Duchesne , Vincent Leroy , Thomas Decaens , Jean-Baptiste Reiser et al.
Clinical and Translational Immunology, 2020, 9 (12), pp.e1208. ⟨10.1002/cti2.1208⟩
Article dans une revue hal-03183870 v1
Image document

IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer

Margaux Hubert , Elisa Gobbini , Coline Couillault , Thien-Phong Vu Manh , Anne-Claire Doffin et al.
Science Immunology, 2020, 5 (46), pp.eaav3942. ⟨10.1126/sciimmunol.aav3942⟩
Article dans une revue hal-02998632 v1
Image document

BDCA1 + cDC2s, BDCA2 + pDCs and BDCA3 + cDC1s reveal distinct pathophysiologic features and impact on clinical outcomes in melanoma patients

Eleonora Sosa Cuevas , Laurissa Ouaguia , Stephane Mouret , Julie Charles , Florence Fraipont et al.
Clinical and Translational Immunology, 2020, 9 (11), pp.e1190. ⟨10.1002/cti2.1190⟩
Article dans une revue hal-03329086 v1
Image document

Circulating and Hepatic BDCA1+, BDCA2+, and BDCA3+ Dendritic Cells Are Differentially Subverted in Patients With Chronic HBV Infection

Laurissa Ouaguia , Vincent Leroy , Tania Dufeu-Duchesne , David Durantel , Thomas Decaens et al.
Frontiers in Immunology, 2019, 10, pp.112. ⟨10.3389/fimmu.2019.00112⟩
Article dans une revue hal-02361633 v1
Image document

Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses

Margaux Hubert , Elisa Gobbini , Nathalie Bendriss-Vermare , Christophe Caux , Jenny Valladeau-Guilemond
Cancers, 2019, 11 (8), pp.1082. ⟨10.3390/cancers11081082⟩
Article dans une revue hal-03769128 v1
Image document

Cold Tumors: A Therapeutic Challenge for Immunotherapy

Paola Bonaventura , Tala Shekarian , Vincent Alcazer , Jenny Valladeau-Guilemond , Sandrine Valsesia-Wittmann et al.
Frontiers in Immunology, 2019, 10, pp.168. ⟨10.3389/fimmu.2019.00168⟩
Article dans une revue (article de synthèse) hal-03769056 v1
Image document

Immune cell dysfunctions in breast cancer patients detected through whole blood multi-parametric flow cytometry assay

E. Verronèse , A. Delgado , Jenny Valladeau-Guilemond , G. Garin , S. Guillemaut et al.
OncoImmunology, 2016, 5 (3), pp.e1100791. ⟨10.1080/2162402X.2015.1100791⟩
Article dans une revue hal-01796186 v1
Image document

Human natural killer cells promote cross-presentation of tumor cell-derived antigens by dendritic cells

Florence Deauvieau , Vincent Ollion , Anne-Claire Doffin , Carole Achard , Jean-François Fonteneau et al.
International Journal of Cancer, 2015, 136 (5), pp.1085-1094. ⟨10.1002/ijc.29087⟩
Article dans une revue inserm-02913986 v1
Image document

A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage

Colette Dezutter-Dambuyant , Isabelle Durand , Laurent Alberti , Nathalie Bendriss-Vermare , Jenny Valladeau-Guilemond et al.
OncoImmunology, 2015, 5, ⟨10.1080/2162402x.2015.1091146⟩
Article dans une revue hal-03045642 v1

Alteration of the langerin oligomerization state affects Birbeck granule formation

Eric Chabrol , Michel Thépaut , Colette Dezutter-Dambuyant , Corinne Vivès , Julien Marcoux et al.
Biophysical Journal, 2015, 108 (3), pp.666-77. ⟨10.1016/j.bpj.2014.10.075⟩
Article dans une revue hal-01150862 v1

Characterization of resident and migratory dendritic cells in human lymph nodes.

Elodie Segura , Jenny Valladeau-Guilemond , Marie-Hélène Donnadieu , Xavier Sastre-Garau , Vassili Soumelis et al.
Journal of Experimental Medicine, 2012, 209 (4), pp.653-60. ⟨10.1084/jem.20111457⟩
Article dans une revue hal-00723792 v1
Image document

HIV-1 clade promoters strongly influence spatial and temporal dynamics of viral replication in vivo.

Mireille Centlivre , Peter Sommer , Marie Michel , Raphaël Ho Tsong Fang , Sandrine Gofflo et al.
Journal of Clinical Investigation, 2010, 115 (2), pp.348-58. ⟨10.1172/JCI200522873⟩
Article dans une revue pasteur-00013742 v1

Poly(I:C)-Treated human langerhans cells promote the differentiation of CD4+ T cells producing IFN-gamma and IL-10.

Laetitia Furio , Hermine Billard , Jenny Valladeau , Josette Péguet-Navarro , Odile Berthier-Vergnes
Journal of Investigative Dermatology, 2009, 129 (8), pp.1963-71. ⟨10.1038/jid.2009.21⟩
Article dans une revue hal-00425195 v1

Structural studies of langerin and birbeck granule: a macromolecular organization model

M. Thepaut , J. Valladeau , A. Nurisso , R. Kahn , B. Arnou et al.
Biochemistry, 2009, pp.2684-2698
Article dans une revue hal-00373987 v1

The HIV-1 clade C promoter is particularly well adapted to replication in the gut in primary infection.

Mireille Centlivre , Peter Sommer , Marie Michel , Raphaël Ho Tsong Fang , Sandrine Gofflo et al.
AIDS. Official journal of the international AIDS Society, 2006, 20 (5), pp.657-66. ⟨10.1097/01.aids.0000216365.38572.2f⟩
Article dans une revue pasteur-00850258 v1

Human Langerhans cells express a specific TLR profile and differentially respond to viruses and Gram-positive bacteria.

Vincent Flacher , Marielle Bouschbacher , Estelle Verronèse , Catherine Massacrier , Vanja Sisirak et al.
Journal of Immunology, 2006, 177 (11), pp.7959-67
Article dans une revue hal-00180965 v1
Image document

Human Langerhans Cells Express a Specific TLR Profile and Differentially Respond to Viruses and Gram-Positive Bacteria

Vincent Flacher , Marielle Bouschbacher , Estelle Verronèse , Catherine Massacrier , Vanja Sisirak et al.
Journal of Immunology, 2006, 177 (11), pp.7959-7967. ⟨10.4049/jimmunol.177.11.7959⟩
Article dans une revue hal-03908429 v1

Characterization of the dendritic cell landscape in human tumors

Jenny Valladeau-Guilemond
Montpellier Infection & Immunology Meeting, Nov 2024, Montpellier, France
Communication dans un congrès hal-04967343 v1

IFN-III primes pDCs for TLR7 activation and antagonizes TGF-β and PGE2 mediated-immune suppression

Alexis Saby , Candice Sakref , Céline Rodriguez , Lyvia Moudombi , Aurelien Voissiere et al.
17th International Symposium on Dendritic Cells, Oct 2024, Barcelona (ES), Spain
Communication dans un congrès hal-04944678 v1

Identification and function of the dendritic cell landscape in human tumors

Jenny Valladeau-Guilemond
11èmes Journée d’Immunologie et Immunothérapie des Cancers (JIIC), Dec 2024, Dijon, France
Communication dans un congrès hal-04967362 v1

Spatial organization and prognostic impact of dendritic cell subsets in a large cohort of triple negative breast cancer patients

Elisa Gobbini , Margaux Hubert , Anne-Claire Doffin , Candice Sakref , Justine Berthet et al.
Club Francophone des Cellules Dendritiques, Dec 2021, Paris, France
Communication dans un congrès hal-04944901 v1

BDCA3hi dendritic cells infiltrate breast and ovarian tumors but are functionally altered

Margaux Hubert , Vincent Ollion , Anne-Claire Doffin , Estelle Verronese , Isabelle Durand et al.
14th International Conference on Innate Immunity, Jun 2017, Heraklion, Greece
Communication dans un congrès hal-04967697 v1

BDCA3hi dendritic cells infiltrate breast and ovarian tumors but are functionally altered

Margaux Hubert , Vincent Ollion , Anne-Claire Doffin , Estelle Verronese , Isabelle Durand et al.
IRCI Symposium 2017, Feb 2017, Lyon, France
Communication dans un congrès hal-04967713 v1

BDCA3hi dendritic cells infiltrate human primary breast tumors and correlate with a good prognosis

Margaux Hubert , Hélène Lopez-Maestre , Coline Couillault , Vincent Ollion , Christophe Sajous et al.
Joint annual meetings of the SFI and AFC, Nov 2017, Reims, France
Communication dans un congrès hal-04967734 v1