Jochen Lang

Professeur Classe Exceptionnelle (CNU), Université de Bordeaux
67
Documents
Affiliations actuelles
  • Université de Bordeaux (UB)
  • Chimie et Biologie des Membranes et des Nanoobjets (CBMN)
Contact

Présentation

TITLES/DIPLOMA : 1998 Privat-docent (HDR), Faculté de Médecine, Université de Genève, CH (Jury: J.L. Charpentier, CH; M. Rodbell, NIH/US; P. Rorsman, SE). 1985 FMGEMS (US Foreign Medical Graduate Examination in Medical Sciences, autorisation to work in US hospitals) 1985 Approbation zum Arzt (Federal Licence to practice) 1984 3. Staatsexamen der Humanmedizin (Final Medical Exam) Albrecht-Ludwig-Universität Freiburg/GER 1984 Thesis in Experimental Medicine, Albrecht-Ludwig Universität Freiburg/GER

POSITIONS : 2010 - Professeur Classe Exceptionnelle (CNU), Université de Bordeaux 2000 - 2010 Professeur 1er classe, Université de Bordeaux I, Institut Européen de Chimie et Biologie 1997 - 2000 Associate Professor, Div. Biochimie Clinique et Diabète Expérimentale, U. Genève, CH; 1990 - 1997 Assistant Professor, Div. Biochimie Clinique et Diabète Expérimentale (Dir. Pr C.B. Wollheim), Faculté de Médecine, Université de Genève, CH 1988 – 1990 Intern, Dept. Intern. Med., Hôpital Univ. de Genève, Genève (CH) (Prof. A. Muller). 1985 - 1988 Postdoctoral fellow, Max-Planck-Institut, Neurobiologie, Dept. Neuropharmacologie, Martinsried (Munich)/RFA (Prof. A. Herz), fellow Max-Planck and DFG. 1984 - 1985 Military service, Staff Surgeon (Stabsarzt), Engineering Corps, Flensburg/RFA

STUDIES : 1983 - 1984 6th year medical school Statdkrankenhaus Karlsruhe/RFA (Chirurgie), Hôpital Universitaire de Genève, CH (Médicine, Pédiatrie) 1983 Internship, Pennsylvania State University Medical Centre, Cardiology, Hershey, Penn./USA 1981 - 1984 Thesis student, Institut für Pharmakologie, Medizinische Fakultät, U Freiburg ” 1979 Internship, Bella Coola General Hospital, Bella Coola Indian Reserve, B.C., Canada 1977 - 1984 Etudes de Médecine Humaine (U Würzburg, U Paris VI, U Freiburg) 1976 - 1977 Military service, Air Force, Hamburg 1976 Humanistisches Abitur (High School Diplolma; German, Latin, Ancient Greek, Math) DISTINCTIONS German University Foundation/Studienstiftung (1977-1984) https://en.wikipedia.org/wiki/Studienstiftung Prix Denber Pinard de l’Université de Genève (1996) ; PEDR (2005-2013, 2015-2019, 2021-2025) PUBLICATIONS

  • Research ID (ORCID) http://orcid.org/0000-0001-6847-5641
  • 75 original articles, (46 as first or last author, h 38, 5716 cit., mean IF 6.4)
  • 10 reviews, 4 book chapters, 2 patents. COMMISSIONS
  • Member, Comité National CNRS (Biologie Cellulaire et Développement, 2008 – 2016)
  • Member, Conseil Scientifique U Bordeaux 1 (2003-2007), CA U Bordeaux I (2008-2012)
  • Co-Director, Doctoral School Sciences de la Vie et de la Santé (2007-2015)
  • Member, Conseil ED Sciences de la Vie et de la Santé (2016-2021)
  • Co-director, Master Biologie Cellulaire - Pathophysiologie (depuis 2003)
  • Member, Administration Council, Société Francophone du Diabète (2016-2020)
  • Member, Scientific Advisory Board, IRIM, Montpellier (2015-2020)

SUPERVISIONS

  • PhD students (100%), 4 postdocs
  • Group Leader 2000 to 2023

MAJOR GRANTS

  • France ANR CoordinatOr: ACI CNRS/MENRT/2005 “supramolecular assembly”, HY-BIOPACS/2010-13, MULTISPOT/2017-20, FUN-NET 2022-25; Co-PI: Exodynamics/2007-10, ISLET CHIP/2013-16, DIABLO/2018-21. OTHER: CNRS PREMATURATION Easy-Screen 2022-2023. LABEX Amadeus (2015-2018; 2019-2021); European Foundation Study of Diabetes (2010-2012), Société Francophone du Diabète (2010-2012; 2020-2022); Albert Renold (2019) Wellcome Trust (2000-2003); CNRS interdisciplinary programs; SATT (University Technology Transfer; 2014-16) FEDER (2003-2007;2008-2012; 2013-2015; 2018-2021),
  • CH (as PI): Fondation Sandoz; Roche Foundation; Fondation Novartis; Sir Jules Thorn Charitable Trust; Fonds National Suisse (No 31-54023.98); Roche MBA Program; HFSP (Co-appliquant); PhD & HDR JURIES OUTSIDE BORDEAUX (last 10 yrs) 2012 M. Bergeron, U Lausanne (CH) ; 2014 Viva, D. Do, Oxford U., UK ; 2015 M. Roussel, U Montpellier ; 2017 D. Kotsouras & J. Pas, Ecole de Mines ; 2018 HDR, M Ravier, Inst Génomique Fonctionnelle, U Montpellier ; 2020 Marta Pérez Francés, U Genève ; 2021 K Saitoski, Inst. Cochin, Paris; 2021 G Daziano, IPMC, Nice; 2021 Bilal Singh, UC Louvain; A Al-Mass, U Montréal, 2022. INSTITUTE EVALUATIONS (last 10 yrs, HCERES or AERES) ENS Paris (IBENS, A. Triller) 2012; Sys2Diag Montpellier, 2012 ; UPR INCI Strasbourg, 2016 EVALUATION COMITTEES (outside France, last 10 yrs) 2015 Chair (PR) Islet Studies, University of Manitoba, Canada; 2019 Uppsala University, Chair Cell Biology committee, Sweden WORKSHOP AND CONFERENCE ORGANISATION (last 10 yrs) 2013 Congress Société Francophone du Diabète (SFD) Chairman session «insulin secretion» 2015 Organisation congress SFD & Chairman session «insulin secretion» with Pr M. Cnop (BE) 2015/16 Abstract Reviewer, American Society Cell Biology 2018 Chairman session “Functional imaging of insulin secretion”, 54th EASD, Berlin 2020 Chairman session “Stem Cells and Micro-Organs”, Keystone Symposium (Santa Fe, NM) Islet Biology: From Gene to Cell to Micro-Organ. INVITATIONS (seminars, congresses, workshops - last 10 yrs) 2010 International BETA-Cell Symposium, U Genève (participation R. Tsien, Nobel 2009) 2011 Oxford University (Host Pr Rorsman):Wolves, VAMPs and Wavelets Université Catholique de Louvain, BE (Host Pr JC Jonas):ADCY8 and -cells 2013 Kobe University (host Pr S Seino) Mechanisms and Regulation of Insulin Secretion Tokyo University (host Dr K Waki) Novel sensor for a bioartificial pancreas 2014 Texas Tech (host Pr N. Moustaid-Moussa) Sensing the demand of insulin ESOT Meeting Innsbruck:Diachip and Diasensor 2015 5th Diabetes Innovation Day, Montpellier 2017 Annual meeting GRAGIL (Islet Transplantation Network ; Genève) 2018 8th EPITA Symposium & 37th AIDPIT Workshop; INNSBRUCK 2e Islet satellite meeting Société Francophone du Diabète, Nantes Montpellier Islet Mini-Symposium Islet Real Time Recording, IGF, U Montpellier Oxford University Boehringer Seminar, UK Islet Recordings:From Physiology to Biotechnology 3rd International Conference “Innovative Technologies In Biomedicine”, Krakow (PL; Polish Society Medical Physics), Bioelectronic Sensors and Therapy of Type 1 Diabetes 2019 U Geneva Medical Faculty, Bioelectronic Sensors in Islet Physiology and Diabetes

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Biologie cellulaire, Endocrinologie, Diabète, ilots pancréatique

Publications

32
7
4
4
4
2
2
2
2
2
1
1
1
1
1
1
7
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
7
5
5
4
4
2
2
1
1
1
1
1
1
46
4
7
6
1
1
1
1
1
1
1
1

Publications

Deposit thumbnail

Smartphone light-driven electrocatalytic polymerization of thiophenes

Gerardo Salinas , Rana Nakar , Getnet Kassahun , Jochen Lang , Matthieu Raoux et al.

Physical Chemistry Chemical Physics, In press, ⟨10.1039/D5CP03956H⟩

Article dans une revue hal-05444773v1

Cyborg pancreatic islet organoids

Jochen Lang , Matthieu Raoux

Science, 2026, 391 (6787), pp.764-765. ⟨10.1126/science.aef2219⟩

Article dans une revue hal-05540560v1
Deposit thumbnail

A micro-organ based microfluidic biosensor for continuous monitoring of glucose levels in vivo

Emilie Puginier , Antoine Pirog , Florence Poulletier de Gannes , Julien Gaitan , Annabelle Hurtier et al.

npj Biosensing, 2026, 3 (1), pp.12. ⟨10.1038/s44328-025-00077-4⟩

Article dans une revue hal-05540550v1

A microfluidic twin islets-on-chip device for on-line electrophysiological monitoring

Marie Lallouet , Loic Olçomendy , Julien Gaitan , Killian Montiège , Marie Monchablon et al.

Lab on a Chip, 2025, 25 (7), pp.1831-1841. ⟨10.1039/D4LC00967C⟩

Article dans une revue hal-05221948v1
Deposit thumbnail

Slow rather than fast calcium events encode physiological inputs and propagate within islets: Lessons from ultrafast imaging on acute pancreatic tissue slices

Matthieu Raoux , Dorian Chapeau , Jochen Lang

Acta Physiologica, 2025, 241 (4), pp.e70028. ⟨10.1111/apha.70028⟩

Article dans une revue hal-05545786v1
Deposit thumbnail

Extracellular electrophysiology on clonal human β-cell spheroids

Emilie Puginier , Karen Leal-Fischer , Julien Gaitan , Marie Lallouet , Pier-Arnaldo Scotti et al.

Frontiers in Endocrinology, 2024, 15, pp.140288. ⟨10.3389/fendo.2024.1402880⟩

Article dans une revue hal-04602778v1
Deposit thumbnail

Islets-on-Chip: A Tool for Real-Time Assessment of Islet Function Prior to Transplantation

Matthieu Raoux , Sandrine Lablanche , Manon Jaffredo , Antoine Pirog , Pierre-Yves Benhamou et al.

Transplant International, 2023, 36, pp.11512. ⟨10.3389/ti.2023.11512⟩

Article dans une revue hal-04390913v1
Deposit thumbnail

Vertical Organic Electrochemical Transistors and Electronics for Low Amplitude Micro‐Organ Signals

Myriam Abarkan , Antoine Pirog , Donnie Mafilaza , Gaurav Pathak , Gilles N'Kaoua et al.

Advanced Science, 2022, 9 (8), pp.2105211. ⟨10.1002/advs.202105211⟩

Article dans une revue hal-03720072v1

Towards the Integration of an Islet-Based Biosensor in Closed-Loop Therapies for Patients With Type 1 Diabetes

Loïc Olçomendy , Louis Cassany , Antoine Pirog , Roberto Franco , Emilie Puginier et al.

Frontiers in Endocrinology, 2022, 13, ⟨10.3389/fendo.2022.795225⟩

Article dans une revue hal-03648913v1

Integrating an Islet-Based Biosensor in the Artificial Pancreas: In Silico Proof-of-Concept

Loïc Olçomendy , Antoine Pirog , Fanny Lebreton , Manon Jaffredo , Louis Cassany et al.

IEEE Transactions on Biomedical Engineering, 2022, IEEE Transactions on Biomedical Engineering, 69 (2), pp.899-909. ⟨10.1109/TBME.2021.3109096⟩

Article dans une revue hal-03342685v1
Deposit thumbnail

Pancreatic α and β cells

Karen Leal Fischer , Manon Jaffredo , Jochen Lang , Matthieu Raoux

Médecine/Sciences, 2021, 37 (8-9), pp.752 - 758. ⟨10.1051/medsci/2021111⟩

Article dans une revue hal-04396518v1
Deposit thumbnail

Dynamic Uni- and Multicellular Patterns Encode Biphasic Activity in Pancreatic Islets

Manon Jaffredo , Eléonore Bertin , Antoine Pirog , Emilie Puginier , Julien Gaitan et al.

Diabetes, 2021, 70, pp.878 - 888. ⟨10.2337/db20-0214⟩

Article dans une revue hal-04396515v1
Deposit thumbnail

Na + ion selectivity study of a crown ether functionalized PEDOT analog

Gerardo Salinas , Ariana Villarroel Marquez , Maël Idir , Shekhar Shinde , Bernardo A. Frontana-Uribe et al.

ChemElectroChem, 2020, 7 (13), pp.2826-2830. ⟨10.1002/celc.202000693⟩

Article dans une revue hal-02869565v1
Deposit thumbnail

Design of Potassium‐Selective Mixed Ion/Electron Conducting Polymers

Ariana Villarroel Marquez , Gerardo Salinas , Myriam Abarkan , Maël Idir , Cyril Brochon et al.

Macromolecular Rapid Communications, 2020, 41 (12), pp.2000134. ⟨10.1002/marc.202000134⟩

Article dans une revue hal-04396525v1
Deposit thumbnail

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment

Zahia Fezoua-Boubegtiten , Benoit Hastoy , Pier Scotti , Alexandra Milochau , Katell Bathany et al.

Biochimica et Biophysica Acta:Biomembranes, 2019, 1861 (3), pp.670-676. ⟨10.1016/j.bbamem.2018.12.011⟩

Article dans une revue hal-02348321v1

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment

Zahia Fezoua-Boubegtiten , Benoit Hastoy , Pier Scotti , Alexandra Milochau , Katell Bathany et al.

Biochimica et Biophysica Acta:Biomembranes, 2019, 1861 (3), pp.670-676. ⟨10.1016/j.bbamem.2018.12.011⟩

Article dans une revue hal-04396539v1
Deposit thumbnail

The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging

Myriam Abarkan , Julien Gaitan , Fanny Lebreton , Romain Perrier , Manon Jaffredo et al.

Molecular metabolism, 2019, 30, pp.152-160. ⟨10.1016/j.molmet.2019.09.011⟩

Article dans une revue hal-02418027v1

Loss-of-function mutations in ADCY3 cause monogenic severe obesity

Sadia Saeed , Amélie Bonnefond , Filippo Tamanini , Muhammad Usman Mirza , Jaida Manzoor et al.

Nature Genetics, 2018, 50 (2), pp.175-179. ⟨10.1038/s41588-017-0023-6⟩

Article dans une revue hal-04535818v1

The glutamate receptor GLUK2 plays a role in glucose homeostasis

Myriam Abarkan , Fanny Lebreton , Romain Perrier , M. Jaffredo , Julien Gaitan et al.

Diabetologia, 2018, 61, pp.S204-S204

Article dans une revue hal-03284672v1
Deposit thumbnail

Multimed: An Integrated, Multi-Application Platform for the Real-Time Recording and Sub-Millisecond Processing of Biosignals

Antoine Pirog , Yannick Bornat , Romain Perrier , Matthieu Raoux , Manon Jaffredo et al.

Sensors, 2018, 18 (7), pp.2099. ⟨10.3390/s18072099⟩

Article dans une revue hal-02499524v1
Deposit thumbnail

A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis

Benoît Hastoy , Pier A Scotti , Alexandra Milochau , Zahia Fezoua-Boubegtiten , Jorge Rodas et al.

Scientific Reports, 2017, 7 (1), pp.2835. ⟨10.1038/s41598-017-03013-3⟩

Article dans une revue hal-04396585v1

Fusion pore in exocytosis: More than an exit gate? A β-cell perspective

Benoit Hastoy , Anne Clark , Patrik Rorsman , Jochen Lang

Cell Calcium, 2017, 68, pp.45-61. ⟨10.1016/j.ceca.2017.10.005⟩

Article dans une revue istex hal-04396581v1

Simultaneous monitoring of single cell and of micro-organ activity by PEDOT:PSS covered multi-electrode arrays

Dimitrios A Koutsouras , Romain Perrier , Ariana Villarroel Marquez , Antoine Pirog , Eileen Pedraza et al.

Materials Science and Engineering: C, 2017, 81, pp.84-89. ⟨10.1016/j.msec.2017.07.028⟩

Article dans une revue istex hal-04396574v1

Simultaneous monitoring of single cell and of micro-organ activity by PEDOT:PSS covered multi-electrode arrays

Dimitrios Koutsouras , Romain Perrier , Ariana Villarroel Marquez , Antoine Pirog , Eileen Pedraza et al.

Materials Science and Engineering: C, 2017, 81, pp.84-89. ⟨10.1016/j.msec.2017.07.028⟩

Article dans une revue istex hal-01578781v1
Deposit thumbnail

Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia

Antonia Solomou , Erwann Philippe , Pauline Chabosseau , Stephanie Migrenne-Li , Julien Gaitan et al.

Nutrition and Metabolism, 2016, 13 (1), pp.46. ⟨10.1186/s12986-016-0104-z⟩

Article dans une revue hal-04396589v1
Deposit thumbnail

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

Francesca Semplici , Angeles Mondragon , Benedict Macintyre , Katja Madeyski-Bengston , Anette Persson-Kry et al.

Diabetologia, 2016, 59 (9), pp.1938-1947. ⟨10.1007/s00125-016-4025-1⟩

Article dans une revue hal-04396598v1

Multilevel control of glucose homeostasis by adenylyl cyclase 8

Matthieu Raoux , Pierre Vacher , Julien Papin , Alexandre Picard , Elzbieta Kostrzewa et al.

Diabetologia, 2015, 58 (4), pp.749-757. ⟨10.1007/s00125-014-3445-z⟩

Article dans une revue hal-01545427v1
Deposit thumbnail

Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes

Eileen Pedraza , Aleksandar Karajić , Matthieu Raoux , Romain Perrier , Antoine Pirog et al.

Lab on a Chip, 2015, 15, ⟨10.1039/C5LC00616C⟩

Article dans une revue hal-01347681v1

Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells

Fanny Lebreton , Antoine Pirog , Isma Belouah , Domenico Bosco , Thierry Berney et al.

Diabetologia, 2015, 58 (6), pp.1291-1299. ⟨10.1007/s00125-015-3558-z⟩

Article dans une revue hal-04396599v1

Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells

Fanny Lebreton , Antoine Pirog , Isma Belouah , Domenico Bosco , Thierry Berney et al.

Diabetologia, 2015, 58 (6), pp.1291-1299. ⟨10.1007/s00125-015-3558-z⟩

Article dans une revue hal-01347716v1
Deposit thumbnail

Biosensors in Diabetes : how to get the most out of evolution and transpose it into a signal

Sylvie Renaud , Bogdan Catargi , Jochen Lang

IEEE pulse, 2014, pp.30-34

Article dans une revue hal-00993190v1
Deposit thumbnail

Non-invasive long-term and real-time analysis of endocrine cells on micro-electrode arrays

Matthieu Raoux , Yannick Bornat , Adam Quotb , Bogdan Catargi , Sylvie Renaud et al.

The Journal of Physiology, 2011, 590 (5), pp.1085-1091

Article dans une revue hal-00742984v1

A charged prominence in the linker domain of the cysteine‐string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis

Frédéric Boal , Michel Laguerre , Alexandra Milochau , Jochen Lang , Pier Scotti

FASEB Journal, 2010, 25 (1), pp.132-143. ⟨10.1096/fj.09-152033⟩

Article dans une revue hal-05316545v1
Deposit thumbnail

Distinct roles of the C 2}A and the C 2}B domain of the vesicular Ca 2+} sensor synaptotagmin 9 in endocrine {beta}-cells

Florence Grise , Nada Taib , Carole Monterrat , Valérie Lagrée , Jochen Lang

Biochemical Journal, 2007, 403 (3), pp.483-492. ⟨10.1042/BJ20061182⟩

Article dans une revue hal-00478645v1

Cysteine‐string proteins regulate exocytosis of insulin independent from transmembrane ion fluxes

Hui Zhang , William Kelley , Luke Chamberlain , Robert Burgoyne , Claes Wollheim et al.

FEBS Letters, 1998, 437 (3), pp.267-272. ⟨10.1016/s0014-5793(98)01233-2⟩

Article dans une revue istex hal-05545824v1

Insulinoma Cells Contain an Isoform of Ca 2؉ / Calmodulin-Dependent Protein Kinase II ␦ Associated with Insulin Secretion Vesicles*

M. Möhlig , S. Wolter , P. Mayer , J. Lang , M. Osterhoff et al.

Endocrinology, 1997, 138 (6), pp.2577-2584. ⟨10.1210/endo.138.6.5168⟩

Article dans une revue hal-05545941v1
Deposit thumbnail

Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca 2 +-stimulated exocytosis of insulin

Catherine Kiraly-Borri , Alan Morgan , Robert Burgoyne , Ulrich Weller , Claes Wollheim et al.

Biochemical Journal, 1996, 314 (1), pp.199-203. ⟨10.1042/bj3140199⟩

Article dans une revue hal-05545966v1

Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells

Romano Regazzi , Mariella Ravazzola , Mariella Iezzi , Jochen Lang , Ahmed Zahraoui et al.

Journal of Cell Science, 1996, 109 (9), pp.2265-2273. ⟨10.1242/jcs.109.9.2265⟩

Article dans une revue hal-05545925v1
Deposit thumbnail

Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases G; and G. or by the expression of their active Ga subunits

J. Lang , I. Nishimoto , T. Okamoto , R. Regazzi , C. Kiraly et al.

The EMBO Journal, 1995, 14 (15), pp.3635-3644. ⟨10.1002/j.1460-2075.1995.tb00033.x⟩

Article dans une revue hal-05545830v1

SNAP-25 Is Expressed in Islets of Langerhans and Is Involved in Insulin Release

K Sadoul , J Lang , C Montecucco , U Weller , R Regazzi et al.

Journal of Cell Biology, 1995, 128 (6), pp.1019-1028. ⟨10.1083/jcb.128.6.1019⟩

Article dans une revue hal-05545960v1

A game plan for exocytosis

C Wollheim , Jochen Lang

Trends in Cell Biology, 1994, 4 (9), pp.339-341. ⟨10.1016/0962-8924(94)90236-4⟩

Article dans une revue istex hal-05545797v1
Deposit thumbnail

Conserved transducer coupling but different effector linkage upon expression of the myeloid fMet-Leu-Phe receptor in insulin secreting cells.

J. Lang , F. Boulay , Guodong Li , C.B. Wollheim

The EMBO Journal, 1993, 12 (7), pp.2671-2679. ⟨10.1002/j.1460-2075.1993.tb05928.x⟩

Article dans une revue hal-05545816v1

Chronic opiate receptor activation in vivo alters the level of g-protein subunits in guinea-pig myenteric plexus

J. Lang , R. Schulz

Neuroscience, 1989, 32 (2), pp.503-510. ⟨10.1016/0306-4522(89)90097-3⟩

Article dans une revue istex hal-05549836v1

Direct modulation of voltage-dependent calcium channels by muscarinic activation of a pertussis toxin-sensitive G-protein in hippocampal neurons

M. Toselli , J. Lang , T. Costa , H. Lux

Pflügers Archiv European Journal of Physiology, 1989, 415 (3), pp.255-261. ⟨10.1007/BF00370874⟩

Article dans une revue istex hal-05549845v1

429 Islets-on-chips for dynamic functional analysis of genetic variants in human IPSC beta cells

R Lartigue , E Virgilio , T Sawatani , D Chapeau , J Lang et al.

61th EASD Annual Meeting of the European Association for the Study of Diabetes, Vienna, 2025, EASD, Sep 2025, Vienne, Austria. pp.226

Communication dans un congrès hal-05542037v1
Deposit thumbnail

10 Deciphering the role of non-beta cells in nutrient homeostasis with an in vitro / in silico approach

D Chapeau , A Pirog , J Gaitan , M Lallouet , L Olcomendy et al.

61th EASD Annual Meeting of the European Association for the Study of Diabetes, Vienna, 2025, EASD, Sep 2025, Wien (Österreich), Austria. ⟨10.1007/s00125-025-06497-1⟩

Communication dans un congrès hal-05542020v1
Deposit thumbnail

451 Meal-like stimulation protocol of beta cells in islets-on-chip and a human in-silico simulator

D Chapeau , L Olcomendy , M Lallouet , T Sawatani , M Monchablon et al.

60th EASD Annual Meeting of the European Association for the Study of Diabetes, Madrid, 2024, EASD, Sep 2024, Madrid, Spain. pp.224, ⟨10.1007/s00125-024-06226-0⟩

Communication dans un congrès hal-05542010v1

Multi-sensor pancreatic-islets-and-muscle-on-chip for real-time studies of glucose homeostasis

Marie Monchablon , Dorian Chapeau , Gilles N'Kaoua , Antoine Pirog , Emilie Puginier et al.

EUROoCS conference on Organ-on-Chip, Jul 2022, Grenoble, France

Communication dans un congrès hal-04099043v1

Continuous monitoring in-vivo with an islet-based microfluidic biosensor

Matthieu Raoux , Emilie Puginier , Antoine Pirog , Florence Poulletier de Gannes , Julien Gaitan et al.

DIABETOLOGIA, Sep 2022, Stockholm, France. pp.S362-S363

Communication dans un congrès hal-03814499v1

Encodage électrique cellulaire et multicellulaire de la sécrétion biphasique d’insuline

Manon Jaffredo , Antoine Pirog , Éléonore Bertin , Bogdan Catargi , Sylvie Renaud et al.

Société Francophone du Diabète (SFD), Mar 2018, Nantes, France

Communication dans un congrès hal-02520933v1

Differential beta cell coupling patterns drive biphasic activity

Manon Jaffredo , Antoine Pirog , Éléonore Bertin , Bogdan Catargi , Sylvie Renaud et al.

54th EASD Annual Meeting of the European Association for the Study of Diabetes :, Oct 2018, Berlin, Germany

Communication dans un congrès hal-02518447v1

Quality control of islets prior to transplantation using micro-electrode arrays coupled to automated real-time signal recognition and data treatment

Matthieu Raoux , Antoine Pirog , Domenico Bosco , Manon Jaffredo , Romain Perrier et al.

8th EPITA Symposium & 37th AIDPIT Workshop, Jan 2018, Innsbruck, Austria

Communication dans un congrès hal-02521011v1

Differential beta cell coupling patterns drive biphasic activity

Manon Jaffredo , Antoine Pirog , Eleonore Bertin , Bogdan Catargi , Sylvie Renaud et al.

54th EASD Annual Meeting of the European Association for the Study of Diabetes, 2018, Berlin, Germany. pp.S17-S18

Communication dans un congrès hal-03181302v1

Décodage des algorithmes endogènes des îlots en temps réel et leur utilisation dans les simulateurs in-silico du sujet sain ou atteint de diabète de type 1

Matthieu Raoux , Éléonore Bertin , Antoine Pirog , Romain Perrier , Manon Jaffredo et al.

Société Francophone du Diabète (SFD), Mar 2017, Lille, France. pp.A5, ⟨10.1016/S1262-3636(17)30122-2⟩

Communication dans un congrès hal-02520987v1
Deposit thumbnail

A versatile electrode sorting module for MEAs: implementation in a FPGA-based real-time system

Antoine Pirog , Yannick Bornat , Sylvie Renaud , Romain Perrier , Manon Jaffredo et al.

13th IEEE Biomedical Circuits and Systems Conference (BioCAS 2017), BioCas, Oct 2017, Turin, Italy. pp.1-4, ⟨10.1109/BIOCAS.2017.8325154⟩

Communication dans un congrès hal-04396567v1
Deposit thumbnail

The Visual Object Tracking VOT2015 Challenge Results

Matej Kristan , Jiri Matas , Aleš Leonardis , Michael Felsberg , Luka Cehovin et al.

Visual Object Tracking Workshop 2015 at ICCV2015, Dec 2015, Santiago, Chile. pp.564-586, ⟨10.1109/ICCVW.2015.79⟩

Communication dans un congrès hal-01336773v1
Deposit thumbnail

A novel bioelectronic glucose sensor to process distinct electrical activities of pancreatic beta-cells

Quang Vinh Nguyen , Anton Caro , Matthieu Raoux , Adam Quotb , Jean-Baptiste Floderer et al.

35th Annual International Conference of the IEEE EMBS, Jul 2013, Japan. pp.172 - 175, ⟨10.1109/EMBC.2013.6609465⟩

Communication dans un congrès hal-00980774v1
Deposit thumbnail

NeuroBetaMed: A re-configurable wavelet-based event detection circuit for in vitro biological signals

Adam Quotb , Yannick Bornat , Matthieu Raoux , Jochen Lang , Sylvie Renaud

Circuits and Systems (ISCAS), 2012 IEEE International Symposium on, May 2012, Seoul, South Korea. pp.1532 - 1535

Communication dans un congrès hal-00742324v1

BioElectronic sensing for insulin demand

Matthieu Raoux , Guilherme Bontorin , Yannick Bornat , Jochen Lang , Sylvie Renaud

R. Jung. BioHybrid systems: Nerves, interfaces and machines, Wiley-VCH, pp.191-201, 2011

Chapitre d'ouvrage hal-00667643v1

Guanine Nucleotide-Binding Proteins and Their Coupling to Opioid Receptors

J. Lang

Neurobiology of Opioids, Springer Berlin Heidelberg, pp.121-140, 1991, ⟨10.1007/978-3-642-46660-1_7⟩

Chapitre d'ouvrage hal-05545933v1