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Julien Barbier

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Autophagic degradation is involved in cell protection against ricin toxin

Yu Wu , Clémence Taisne , Nassim Mahtal , Alison Forrester , Marion Lussignol
Toxins, 2023, 15 (5), pp.304. ⟨10.3390/toxins15050304⟩
Journal articles cea-04352580v1
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A New Derivative of Retro-2 Displays Antiviral Activity against Respiratory Syncytial Virus

Adrien Le Rouzic , Jenna Fix , Robin Vinck , Sandrine Kappler-Gratias , Romain Volmer
International Journal of Molecular Sciences, 2023, 25 (1), pp.415. ⟨10.3390/ijms25010415⟩
Journal articles hal-04408762v1
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Antiviral effects of ABMA and DABMA against Influenza virus In vitro and In vivo via regulating the endolysosomal pathway and autophagy

Hongtao Liu , Chunlai Jiang , Yu Wu , Min Wu , Jiaxin Wu
International Journal of Molecular Sciences, 2022, 23 (7), pp.3940. ⟨10.3390/ijms23073940⟩
Journal articles cea-04352635v1
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In vivo sustained release of the retrograde transport inhibitor retro-2.1 formulated in a thermosensitive hydrogel

Robin Vinck , Laetitia Anvi Nguyen , Mathilde Munier , Lucie Caramelle , Diana Karpman
International Journal of Molecular Sciences, 2022, 23, pp.14611. ⟨10.3390/ijms232314611⟩
Journal articles cea-04352592v1

In Vivo Sustained Release of the Retrograde Transport Inhibitor Retro-2.1 Formulated in a Thermosensitive Hydrogel

Robin Vinck , Anvi Laetitia Nguyen , Mathilde Munier , Lucie Caramelle , Diana Karpman
International Journal of Molecular Sciences, 2022, 23 (23), pp.14611. ⟨10.3390/ijms232314611⟩
Journal articles hal-04433359v1

An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis

Sébastien Pomel , Sandrine Cojean , Valérie Pons , Jean-Christophe Cintrat , Anvi Laetitia Nguyen
Journal of Antimicrobial Chemotherapy, 2021, 76 (10), pp.2640-2650. ⟨10.1093/jac/dkab226⟩
Journal articles hal-04433354v1

An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis

Sébastien Pomel , Sandrine Cojean , Valérie Pons , Jean-Christophe Cintrat , Laetitia Nguyen
Journal of Antimicrobial Chemotherapy, 2021, 76 (10), pp.2640-2650. ⟨10.1093/jac/dkab226⟩
Journal articles cea-04352695v1
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Structure–Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin

Hajer Abdelkafi , Aurélien Michau , Valérie Pons , Flora Ngadjeua , Alexandra Clerget
Journal of Medicinal Chemistry, 2020, 63 (15), pp.8114-8133. ⟨10.1021/acs.jmedchem.0c00298⟩
Journal articles hal-03320788v1
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Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins

Nassim Mahtal , Yu Wu , Jean-Christophe Cintrat , Julien Barbier , Emmanuel Lemichez
Toxins, 2020, 12 (1), pp.26. ⟨10.3390/toxins12010026⟩
Journal articles pasteur-02448862v1
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Shiga Toxin Uptake and Sequestration in Extracellular Vesicles Is Mediated by Its B-Subunit

Annie Willysson , Anne-Lie Ståhl , Daniel Gillet , Julien Barbier , Jean-Christophe Cintrat
Toxins, 2020, 12 (7), ⟨10.3390/toxins12070449⟩
Journal articles cea-03023143v1

Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2

Alison Forrester , Stefan Rathjen , Maria Daniela Garcia-Castillo , Collin Bachert , Audrey Couhert
Nature Chemical Biology, 2020, 16 (3), pp.327-336. ⟨10.1038/s41589-020-0474-4⟩
Journal articles hal-04003230v1

DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses

Yu Wu , Valérie Pons , Romain Noël , Sabrina Kali , Olena Shtanko
ACS Medicinal Chemistry Letters, 2019, 10 (8), pp.1140-1147. ⟨10.1021/acsmedchemlett.9b00155⟩
Journal articles pasteur-02453943v1

Retro-2 and its dihydroquinazolinone derivatives inhibit filovirus infection

Olena Shtanko , Yasuteru Sakurai , Ann Reyes , Romain Noël , Jean-Christophe Cintrat
Antiviral Research, 2018, ⟨10.1016/j.antiviral.2017.11.016⟩
Journal articles hal-04352731v1
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Editorial : 23rd and 24th Meetings of the French Society of Toxinology (SFET): Special issue on "Toxins: Immunity, Inflammation and Pain"

Evelyne Benoit , Julien Barbier , Jordi Molgó
Toxicon, 2018, 149, pp.1 - 5. ⟨10.1016/j.toxicon.2018.04.020⟩
Journal articles hal-01828958v1

Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1

Nassim Mahtal , Clémence Brewee , Sylvain Pichard , Orane Visvikis , Jean-Christophe Cintrat
ChemMedChem, 2018, 13 (7), pp.754-761. ⟨10.1002/cmdc.201700631⟩
Journal articles pasteur-02448858v1

Antiviral Effect of Retro-2.1 against Herpes Simplex Virus Type 2 In Vitro

Wen Wen Dai , Yu Wu , Jin Peng Bi , Jing Yu Wang , Shuai Wang
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2018, ⟨10.4014/jmb.1712.12052⟩
Journal articles hal-04352689v1
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Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo

Wenwen Dai , Yu Wu , Jinpeng Bi , Shuai Wang , Fang Li
Viruses, 2018, 10 (3), pp.119. ⟨10.3390/v10030119⟩
Journal articles cea-02432376v1
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ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments

Yu Wu , Valérie Pons , Amélie Goudet , Laetitia Panigai , Annette Fischer
Scientific Reports, 2017, 7 (1), pp.15567. ⟨10.1038/s41598-017-15466-7⟩
Journal articles pasteur-01675662v1
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Editorial : Special Issue on "Toxins: New targets and new functions".

Evelyne Benoit , Julien Barbier , Michel R Popoff , Grazyna Faure , Jordi Molgó
Toxicon, 2016, 116, pp.1-3. ⟨10.1016/j.toxicon.2016.03.012⟩
Journal articles hal-01306142v1

Correction: The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH.

Anne Araye , Amélie Goudet , Julien Barbier , Sylvain Pichard , Bruno Baron
PLoS ONE, 2016, pp.e0161743. ⟨10.1371/journal.pone.0161743⟩
Journal articles hal-01452079v1
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The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH

Anne Araye , Amélie Goudet , Julien Barbier , Sylvain Pichard , Bruno Baron
PLoS ONE, 2016, 11 (4), pp.e0153401. ⟨10.1371/journal.pone.0153401⟩
Journal articles pasteur-01378747v1

Retrograde trafficking inhibitor of Shiga toxins reduces morbidity and mortality of mice infected with enterohemorrhagic Escherichia coli

Thomas Secher , Ayaka Shima , Karen Hinsinger , Jean Christophe Cintrat , Ludger Johannes
Antimicrobial Agents and Chemotherapy, 2015, 59 (8), pp.5010-5013. ⟨10.1128/AAC.00455-15⟩
Journal articles hal-02640796v1
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Editorial : Special Issue on "freshwater and marine toxins".

Evelyne Benoit , César Mattei , Julien Barbier , Pascale Marchot , Jordi Molgó
Toxicon, 2014, 91, pp.1-4. ⟨10.1016/j.toxicon.2014.11.217⟩
Journal articles hal-01165542v1
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The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

Xin Ming , Kyle Carver , Michael Fisher , Romain Noël , Jean-Christophe Cintrat
Nucleic Acids Research, 2013, 41 (6), pp.3673-3687. ⟨10.1093/nar/gkt066⟩
Journal articles cea-02432369v1
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Editorial : Special issue on "toxins: from threats to benefits".

Marie-France Martin-Eauclaire , Evelyne Benoit , Pascale Marchot , Julien Barbier , Jordi Molgó
Toxicon, 2013, 75, pp.1-2. ⟨10.1016/j.toxicon.2013.08.001⟩
Journal articles hal-00919888v1
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Inhibitors of the Cellular Trafficking of Ricin

Julien Barbier , Céline Bouclier , Ludger Johannes , Daniel Gillet
Toxins, 2012, 4, pp.15-27. ⟨10.3390/toxins4010015⟩
Journal articles cea-02432365v1

Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain

Anne Chassaing , Sylvain Pichard , Anne Araye-Guet , Julien Barbier , Vincent Forge
FEBS Journal, 2011, 278 (23), pp.4516-45525. ⟨10.1111/j.1742-4658.2011.08053.x⟩
Journal articles hal-01138149v1

Inhibition of retrograde transport protects mice from lethal ricin challenge.

Bahne Stechmann , Siau-Kun Bai , Emilie Gobbo , Roman Lopez , Goulven Merer
Cell, 2010, 141 (2), pp.231-42. ⟨10.1016/j.cell.2010.01.043⟩
Journal articles hal-00509058v1

Glycerotoxin stimulates neurotransmitter release from N-type Ca2+ channel expressing neurons.

Mitja Schenning , Dustin T. Proctor , Lotten Ragnarsson , Julien Barbier , Nickolas A. Lavidis
Journal of Neurochemistry, 2006, 98 (3), pp.894-904. ⟨10.1111/j.1471-4159.2006.03938.x⟩
Journal articles hal-00087596v1

Brain-derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C-terminal fragment fusion proteins in mature mouse motor nerve terminals.

Sylvie Roux , Cécile Saint Cloment , Thomas Curie , Emmanuelle Girard , Francisco-Javier Miana Mena
European Journal of Neuroscience, 2006, 24 (6), pp.1546-1554. ⟨10.1111/j.1460-9568.2006.05030.x⟩
Journal articles hal-00105586v1

Xestospongin B, a competitive inhibitor of IP3-mediated Ca2+ signalling in cultured rat myotubes, isolated myonuclei, and neuroblastoma (NG108-15) cells

Enrique Jaimovich , César Mattei , José Luis Liberona , Cesar Cárdenas , Manuel Estrada
FEBS Letters, 2005, 579(10), pp.2051-2057. ⟨10.1016/j.febslet.2005.02.053⟩
Journal articles hal-00086080v1

Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions.

Sylvie Roux , Cesare Colasante , Cécile Saint Cloment , Julien Barbier , Thomas Curie
Molecular and Cellular Neuroscience, 2005, 30 (4), pp.572-582. ⟨10.1016/j.mcn.2005.05.008⟩
Journal articles hal-00109564v1

Cholinesterases and the resistance of the mouse diaphragm to the effect of tubocurarine.

Tu Nguyen-Huu , Alexandre Dobbertin , Julien Barbier , Jasmina Minic , Eric Krejci
Anesthesiology, 2005, 103 (4), pp.788-795
Journal articles hal-00129516v1

Synaptic remodeling at the skeletal neuromuscular junction of acetylcholinesterase knockout mice and its physiological relevance

Emmanuelle Girard , Julien Barbier , Arnaud Chatonnet , E. Krejci , Jordi Molgó
Chemico-Biological Interactions, 2005, 157-158, pp.87-96. ⟨10.1016/j.cbi.2005.10.010⟩
Journal articles hal-00021454v1

Electrophysiological and morphological characterization of a case of autosomal recessive congenital myasthenic syndrome with acetylcholine receptor deficiency due to a N88K rapsyn homozygous mutation.

Eriko Yasaki , Cassandra Prioleau , Julien Barbier , Pascale Richard , Frédéric Andreux
Neuromuscul Disord, 2004, 14 (1), pp.24-32. ⟨10.1016/j.nmd.2003.07.002⟩
Journal articles hal-00136526v1

NMR solution structures of delta-conotoxin EVIA from Conus ermineus that selectively acts on vertebrate neuronal Na+ channels.

Laurent Volpon , Hung Lamthanh , Julien Barbier , Nicolas Gilles , Jordi Molgó
Journal of Biological Chemistry, 2004, 279 (20), pp.21356-21366. ⟨10.1074/jbc.M309594200⟩
Journal articles hal-00136554v1

A delta-conotoxin from Conus ermineus venom inhibits inactivation in vertebrate neuronal Na+ channels but not in skeletal and cardiac muscles.

Julien Barbier , Hung Lamthanh , Frédéric Le Gall , Philippe Favreau , Evelyne Benoit
Journal of Biological Chemistry, 2004, 279 (6), pp.4680-4685. ⟨10.1074/jbc.M309576200⟩
Journal articles hal-00136492v1

Degeneration and regeneration of murine skeletal neuromuscular junctions after intramuscular injection with a sublethal dose of Clostridium sordellii lethal toxin.

Julien Barbier , Michel R Popoff , Jordi Molgó
Infection and Immunity, 2004, 72 (6), pp.3120-3128. ⟨10.1128/IAI.72.6.3120-3128.2004⟩
Journal articles hal-00169722v1

Contryphan-Vn: a modulator of Ca2+-dependent K+ channels.

Gabriella Raybaudi Massilia , Tommaso Eliseo , Francoise Grolleau , Bruno Lapied , Julien Barbier
Biochemical and Biophysical Research Communications, 2003, 303 (1), pp.238-46. ⟨10.1016/S0006-291X(03)00331-0⟩
Journal articles hal-00188894v1

Neuromuscular alterations and synaptic remodelling after exposure to clostridial toxins

Julien Barbier , Michel R. Popoff , Jordi Molgó
D. Gillet and L. Johannes. Recent Research Developments in Toxins from Bacteria and Other Organisms, Research Signpost, Kerala, India, pp.301-326, 2006, ISBN: 81-7736-268-2
Book sections hal-00105901v1

Bacterial toxins with intracellular targets

Julien Barbier , Jordi Molgó
S.G. Pandalai. Recent Research Developments in Cell Science (vol.1), Transworld Research Network, Trivandrum, Kerala, Inde, pp.217-239, 2004, Monographie - ISBN: 81-7895-112-6
Book sections hal-00183648v1

Synaptic transmission at AChE-/- and ColQ-/- knockout mouse neuromuscular junctions

Jasmina Minic , Julien Barbier , Arnaud Chatonnet , Jordi Molgó
N. Inestrosa & E. O. Campos. Cholinesterase in the Second Millennium : Biomolecular and Pathological Aspects, Diseño e Impresiones J&J Ltda, Chile, pp.19-23, 2004, ISBN: 956-299-127-X
Book sections hal-00183322v1

Conotoxins targeting voltage-sensitive sodium channels

Julien Barbier , Evelyne Benoit , Jordi Molgó
P. Ascenzi F. Polticelli & P. Visca. Bacterial, Plant and Animal toxins, Research Signpost (Trivandrum, Kerala, India), pp.127-145, 2003, ISBN: 81-271-0037-4
Book sections hal-00189355v1

Les conotoxines: de nouveaux outils pour étudier la diversité des canaux Na+ sensibles au potentiel de membrane

Julien Barbier , Evelyne Benoit , Jordi Molgó
F. Goudey-Perriere, E. Benoit, C. Bon & S. Puiseux-Dao. Toxinogenèse – Biosynthèse, ingénierie, polymorphisme, neutralisation des toxines, Elsevier, pp.157-166, 2003, ISBN: 2-84299-481-7 / Ean 13 : 9782842994815
Book sections hal-00189402v1

Implication des réserves intracellulaires de Ca2+ dans l'augmentation de la libération d'acétylcholine indépendante du Ca2+ externe et provoquée par la brévétoxine-3

Emmanuelle Girard , Julien Barbier , Evelyne Benoit , Dominique Laurent , Jordi Molgó
F. Goudey-Perriere, E. Benoit, C. Bon & S. Puiseux-Dao. Toxinogenèse – Biosynthèse, ingénierie, polymorphisme, neutralisation des toxines, Elsevier, pp.81-86, 2003, ISBN: 2-84299-481-7 / Ean 13 : 9782842994815
Book sections hal-00189404v1

Les toxines clostridiales de haut poids moléculaire agissant sur les petites protéines G

Julien Barbier , Michel R Popoff , Michel Thieffry , Jordi Molgó
F. Goudey-Perriere, C. Bon, S. Puiseux-Dao & M-P Sauviat. Toxines et recherches biomédicales (Coll. Rencontres en Toxinologie SFET), Elsevier, Paris, pp.65-74, 2002, ISBN: 2-84299-445-0
Book sections hal-00194105v1

Ribosome Inactivating Proteins: From Plant Defense to Treatments against Human Misuse or Diseases

Julien Barbier , Daniel Gillet
Special issue hal-04352715v1

Toxins: New Targets and New Functions

Jordi Molgó , Evelyne Benoit , Julien Barbier , Michel Popoff , Grazyna Faure
J. MOLGO, E. BENOIT, J. BARBIER, M.R. POPPOF, G. FAURE & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: New Targets and New Functions » organisées par la Société Française pour l'Etude des Toxines, Dec 2014, Paris, France. Toxicon, 116, 2016, Special issue of Toxicon, 0041-0101
Special issue hal-02334653v1

Freshwater and Marine Toxins

Jordi Molgó , Evelyne Benoit , Julien Barbier , Pascale Marchot , Denis Servent
J. MOLGO, E. BENOIT, J. BARBIER, P. MARCHOT & D. SERVENT (Eds). Rencontres en Toxinologie « Freshwater and Marine Toxins » organisées par la Société Française pour l'Etude des Toxines, Dec 2013, Paris, France. Toxicon, 91, 2014, Special issue of Toxicon, 0041-0101
Special issue hal-02334647v1

Toxins: From Threats to Benefits

Jordi Molgó , Evelyne Benoit , Julien Barbier , Pascale Marchot , Denis Servent
J. MOLGO, E. BENOIT, J. BARBIER, P. MARCHOT & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: From Threats to Benefits » organisées par la Société Française pour l'Etude des Toxines (2012), Dec 2012, Paris, France. Toxicon, 75, 2013, Special issue of Toxicon, 0041-0101
Special issue hal-02334645v1