Accéder directement au contenu

Kai Wengelnik

16
Documents

Publications

Image document

Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion

Rakhee Lohia , Benoit Allegrini , Laurence Berry , Hélène Guizouarn , Rachel Cerdan
Cellular and Molecular Life Sciences, 2023, 80 (5), pp.124. ⟨10.1007/s00018-023-04773-0⟩
Article dans une revue hal-04094157v1

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection

Shang Ma , Stuart Cahalan , Gregory Lamonte , Nathan Grubaugh , Weizheng Zeng
Cell, 2018, 173 (2), pp.443-455.e12. ⟨10.1016/j.cell.2018.02.047⟩
Article dans une revue hal-03246965v1
Image document

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

Sharon Wein , Salma Ghezal , Corinne Bure , Marjorie Maynadier , Christian Perigaud
Journal of Lipid Research, 2018, 59 (8), pp.1461-1471. ⟨10.1194/jlr.M085589⟩
Article dans une revue hal-02535449v1

Phosphoinositides and their functions in apicomplexan parasites

Kai Wengelnik , Wassim Daher , Maryse Lebrun
International Journal for Parasitology, 2018, 48 (7), pp.493-504. ⟨10.1016/j.ijpara.2018.01.009⟩
Article dans une revue hal-03247070v1

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

Ellen Bushell , Ana Rita Gomes , Theo Sanderson , Burcu Anar , Gareth Girling
Cell, 2017, 170 (2), pp.260-272.e8. ⟨10.1016/j.cell.2017.06.030⟩
Article dans une revue hal-04243702v1

Plasmodium falciparum CTP:phosphocholine cytidylyltransferase possesses two functional catalytic domains and is inhibited by a CDP-choline analog selected from a virtual screening

Alicia Contet , Émilie Pihan , Marina Lavigne , Kai Wengelnik , Sweta Maheshwari
FEBS Letters, 2015, 589 (9), pp.992-1000. ⟨10.1016/j.febslet.2015.03.003⟩
Article dans une revue hal-02115813v1

Lipid kinases are essential for apicoplast homeostasis in T oxoplasma gondii

Wassim Daher , Juliette Morlon-Guyot , Lilach Sheiner , Gaëlle Lentini , Laurence Berry
Cellular Microbiology, 2015, 17 (4), pp.559-578. ⟨10.1111/cmi.12383⟩
Article dans une revue hal-03246901v1

Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active

Sweta Maheshwari , Marina Lavigne , Alicia Contet , Blandine Alberge , Émilie Pihan
Biochemical Journal, 2013, 450 (1), pp.159-167. ⟨10.1042/BJ20121480⟩
Article dans une revue hal-02115788v1
Image document

Phosphatidylinositol 3-Monophosphate Is Involved in Toxoplasma Apicoplast Biogenesis

Lina Tawk , Jean-François Dubremetz , Philippe Montcourrier , Gaëtan Chicanne , Fabrice Merezegue
PLoS Pathogens, 2011, 7 (2), pp.e1001286. ⟨10.1371/journal.ppat.1001286⟩
Article dans une revue hal-03246879v1

Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation

Andreas Raabe , Kai Wengelnik , Oliver Billker , Henri Vial
Cellular Microbiology, 2011, 13 (7), pp.955-966. ⟨10.1111/j.1462-5822.2011.01591.x⟩
Article dans une revue hal-03246892v1
Image document

Genetic and transcriptional analysis of phosphoinositide-specific phospholipase C in Plasmodium

Andreas Raabe , Laurence Berry , Lauriane Sollelis , Rachel Cerdan , Lina Tawk
Experimental Parasitology, 2011, 129 (1), pp.75-80. ⟨10.1016/j.exppara.2011.05.023⟩
Article dans une revue hal-04121786v1

Phosphatidylinositol 3-Phosphate, an Essential Lipid in Plasmodium, Localizes to the Food Vacuole Membrane and the Apicoplast

Lina Tawk , Gaëtan Chicanne , Jean-François Dubremetz , Véronique Richard , Bernard Payrastre
Eukaryotic Cell, 2010, 9 (10), pp.1519-1530. ⟨10.1128/EC.00124-10⟩
Article dans une revue hal-03246870v1

The Kennedy phospholipid biosynthesis pathways are refractory to genetic disruption in Plasmodium berghei and therefore appear essential in blood stages

Sandrine Déchamps , Kai Wengelnik , Laurence Berry-Sterkers , Rachel Cerdan , Henri Vial
Molecular and Biochemical Parasitology, 2010, 173 (2), pp.69-80. ⟨10.1016/j.molbiopara.2010.05.006⟩
Article dans une revue hal-02281791v1
Image document

Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei

Andreas Raabe , Oliver Billker , Henri Vial , Kai Wengelnik
Molecular and Biochemical Parasitology, 2009, 168 (2), pp.172-176. ⟨10.1016/j.molbiopara.2009.08.004⟩
Article dans une revue hal-03246862v1

Characterization of Plasmodium falciparum CDP-diacylglycerol synthase, a proteolytically cleaved enzyme

Dominique P. Martin , Leila Gannoun-Zaki , Serge Bonnefoy , Patrick Eldin , Kai Wengelnik
Molecular and Biochemical Parasitology, 2000, 110 (1), pp.93-105. ⟨10.1016/s0166-6851(00)00260-7⟩
Article dans une revue hal-02281921v1

The A-domain and the thrombospondin-related motif of Plasmodium falciparum TRAP are implicated in the invasion process of mosquito salivary glands

K. Wengelnik
EMBO Journal, 1999, 18 (19), pp.5195-5204. ⟨10.1093/emboj/18.19.5195⟩
Article dans une revue hal-03246848v1