Kevin Cariou

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Documents

Publications

Publications

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Design, Synthesis, and Evaluation of Organic and Organometallic Pyrazoline Derivatives as Selective Dual COX-2/5-LOX Inhibitors and Potential Anticancer Agents

Elizabeth Navarrete , Tomás Cáceres M , Pilar Morales , Michelle Muñoz-Osses , Olivier Blacque et al.

Journal of Medicinal Chemistry, 2026, ⟨10.1021/acs.jmedchem.5c02815⟩

Article dans une revue hal-05450044v1
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Synthesis, Characterization, and Biological Evaluation of Red Light‐Activatable BODIPY‐Caged Ceritinib Compounds

Kirill M Kuznetsov , Kallol Purkait , Pierre Mesdom , Philippe Arnoux , Céline Frochot et al.

Helvetica Chimica Acta, In press, ⟨10.1002/hlca.202500023⟩

Article dans une revue hal-05037869v1
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Metal‐Catalyzed Cross‐Coupling for the Synthesis of β‐Lactam Drugs and Related Chemical Probes

Jules Bresson , Katie Burke , Mélanie Ethève‐quelquejeu , Laura Iannazzo , Kevin Cariou

ChemMedChem, 2025, 20 (9), pp.e202400960. ⟨10.1002/cmdc.202400960⟩

Article dans une revue hal-05287299v1
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A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery

Inga Černauskienė , Eduardo Izquierdo‐garcía , Sarah Keller , Harley Betts , Kevin Cariou et al.

Angewandte Chemie International Edition, 2025, ⟨10.1002/anie.202513808⟩

Article dans une revue hal-05354488v1
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EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model

Jean Delabar , Marco Antônio G.B. Gomes , Marta Fructuoso , Nadège Sarrazin , Nicolas George et al.

European Journal of Medicinal Chemistry, 2024, 265, pp.116098. ⟨10.1016/j.ejmech.2023.116098⟩

Article dans une revue hal-05387931v1

A Near-Infrared-Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy inducing Immunogenic Cell Death

Yiyi Zhang , Pierre Mesdom , Eduardo Izquierdo-García , João António , Bruno Saubamea et al. Article dans une revue hal-05389603v1
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N-Metallocenyl Ynamides: Preparation, Reactivity and Synthesis of ansa[3]-Ferrocenylamides

Capucine Mahe , Olivier Blacque , Gilles Gasser , Vincent Gandon , Kevin Cariou

Organic Letters, 2023, ⟨10.1021/acs.orglett.2c04169⟩

Article dans une revue hal-03966748v1
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Base‐Mediated Generation of Ketenimines from Ynamides: Addition of Hydrazones to Give Acetimidohydrazides**

Capucine Mahe , Agathe C A d'Hollander , Kevin Cariou

European Journal of Organic Chemistry, 2022, 2022 (18), pp.e202200028. ⟨10.1002/ejoc.202200028⟩

Article dans une revue hal-03721985v1
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Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

Lisa Gourdon , Kevin Cariou , Gilles Gasser

Chemical Society Reviews, 2022, ⟨10.1039/D1CS00609F⟩

Article dans une revue hal-03542713v1
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Base-Mediated Generation of Ketenimines from Ynamides: [3+2] Annulation with Azaallyl Anions

Agathe C A d'Hollander , Eugénie Romero , Kamsana Vijayakumar , Camille Le Houérou , Pascal Retailleau et al.

Advanced Synthesis and Catalysis, 2021, 363 (11), pp.2903-2908. ⟨10.1002/adsc.202100047⟩

Article dans une revue hal-03227971v1
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Photoinduced Aerobic Iodoarene-Catalyzed Spirocyclization of N-Oxy-Amides to N-Fused Spirolactams

Loïc Habert , Kevin Cariou

Angewandte Chemie International Edition, 2021, 60 (1), pp.171-175. ⟨10.1002/anie.202009175⟩

Article dans une revue hal-03367856v1
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Synthesis, Characterization and Antiparasitic Activity of Organometallic Derivatives of the Anthelmintic Drug Albendazole

Yan Lin , Yih Ching Ong , Sarah Keller , Rafika Bouchene , Eric Manoury et al.

Dalton Transactions, 2020, 49 (20), pp.6616-6626. ⟨10.1039/d0dt01107j⟩

Article dans une revue hal-02555378v1
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Ynamides in Free Radical Reactions

Capucine Mahe , Kevin Cariou

Advanced Synthesis and Catalysis, In press, ⟨10.1002/adsc.202000849⟩

Article dans une revue hal-02962628v1
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Synthetic approaches towards avibactam and other diazabicyclooctane β-lactamase inhibitors

Laure Peilleron , Kevin Cariou

Organic & Biomolecular Chemistry, 2020, ⟨10.1039/C9OB02605C⟩

Article dans une revue hal-02466833v1
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Synthesis of cyclic N-hydroxylated ureas and oxazolidinone oximes enabled by chemoselective iodine(III)-mediated radical or cationic cyclizations of unsaturated N-alkoxyureas

Laure Peilleron , Pascal Retailleau , Kevin Cariou

Advanced Synthesis and Catalysis, 2019, 361 (22), pp.5160-5169. ⟨10.1002/adsc.201901135⟩

Article dans une revue hal-02403999v1
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Halonium-Induced Polyene Cyclizations

Agathe D’hollander , Laure Peilleron , Tatyana Grayfer , Kevin Cariou

Synthesis: Journal of Synthetic Organic Chemistry, 2019, 51 (08), pp.1753-1769. ⟨10.1055/s-0037-1612254⟩

Article dans une revue hal-02307164v1
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A tutorial for the assessment of the stability of organometallic complexes in biological media

Sarah Keller , Yih Ching Ong , Yan Lin , Kevin Cariou , Gilles Gasser

Journal of Organometallic Chemistry, 2019, pp.121059. ⟨10.1016/j.jorganchem.2019.121059⟩

Article dans une revue hal-02393969v1
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Ketenimines Generated from Ynamides: Versatile Building Blocks for Nitrogen-Containing Scaffolds

Robert H Dodd , Kevin Cariou

Chemistry - A European Journal, 2018, 24 (10), pp.2297-2304. ⟨10.1002/chem.201704689⟩

Article dans une revue hal-02307203v1
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DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives

Fernanda Neumann , Stéphanie Gourdain , Christelle Albac , Alain D Dekker , Linh Chi Bui et al.

Scientific Reports, 2018, 8, pp.2859. ⟨10.1038/s41598-018-20984-z⟩

Article dans une revue hal-02292094v1
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Iodine(III)-mediated halogenations of acyclic monoterpenoids

Laure Peilleron , Tatyana Grayfer , Joëlle Dubois , Robert H Dodd , Kevin Cariou et al.

Beilstein Journal of Organic Chemistry, 2018, 14, pp.1103-1111. ⟨10.3762/bjoc.14.96⟩

Article dans une revue hal-02307167v1
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Synthesis of Orthogonally N-Protected, C-4 Functionalized Cyclic Guanidines from L-Serine

Diego Silva , Edmilson Maria , Rosa Suárez Ordóñez , Josiane Thierry , Kevin Cariou et al.

SYNLETT, 2017, 28 (07), pp.815-818. ⟨10.1055/s-0036-1589935⟩

Article dans une revue hal-02307213v1
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Chemodivergent, Tunable, and Selective Iodine(III)-Mediated Bromo-Functionalizations of Polyprenoids

Tatyana Grayfer , Pascal ́ Retailleau , Robert H Dodd , Joëlle Dubois , Kevin Cariou

Organic Letters, 2017, 19 (18), pp.4766-4769. ⟨10.1021/acs.orglett.7b02125⟩

Article dans une revue hal-02307207v1
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Base-Mediated Generation of Ketenimines from Ynamides: Direct Access to Azetidinimines by an Imino Staudinger Synthesis

Eugénie Romero , Corinne Minard , Mohamed Benchekroun , Sandrine Ventre , Pascal ́ Retailleau et al.

Chemistry - A European Journal, 2017, 23 (53), pp.12991-12994. ⟨10.1002/chem.201702545⟩

Article dans une revue hal-02307210v1
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PIFA-mediated ethoxyiodination of enamides with potassium iodide

R. Beltran , S. Nocquet-Thibault , Fabian Blanchard , R. Dodd , K. Cariou

Organic & Biomolecular Chemistry, 2016, 14 (36), pp.8448-8451. ⟨10.1039/C6OB01673A⟩

Article dans une revue hal-02307217v1
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Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation and Preliminary SAR Studies

Tatyana Grayfer , Philippe Grellier , Elisabeth Mouray , Robert H Dodd , Joëlle Dubois et al.

Organic Letters, 2016, 18 (4), pp.708-711. ⟨10.1021/acs.orglett.5b03676⟩

Article dans une revue hal-02420932v1

Assessing Ligand and Counterion Effects in the Noble Metal Catalyzed Cycloisomerization Reactions of 1,6-Allenynes: a Combined Experimental and Theoretical Approach

Florian Jaroschik , Antoine Simonneau , Gilles Lemiere , Kevin Cariou , Nicolas Agenet et al.

ACS Catalysis, 2016, 6 (8), pp.5146-5160. ⟨10.1021/acscatal.5b02696⟩

Article dans une revue hal-01397955v1
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Halocyclization of Unsaturated Guanidines Mediated by Koser's Reagent and Lithium Halides.

Marion Daniel , Florent Blanchard , Sophie Nocquet-Thibault , Kevin Cariou , Robert H Dodd

Journal of Organic Chemistry, 2015, 80 (21), pp.10624-33. ⟨10.1021/acs.joc.5b01750⟩

Article dans une revue hal-03023458v1
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Iodine(III)-mediated diazidation and azido-oxyamination of enamides

S. Nocquet-Thibault , Anita Marie Rayar , Pascal ́ Retailleau , Kevin Cariou , Robert Dodd

Chemistry - A European Journal, 2015, 21 (40), pp.14205-14210. ⟨10.1002/chem.201501782⟩

Article dans une revue istex hal-03026966v1
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Selective Suzuki-Miyaura monocouplings with symmetrical dibromoarenes and aryl ditriflates for the one-pot synthesis of unsymmetrical triaryls

C. Minard , C. Palacio , K. Cariou , Robert H Dodd

European Journal of Organic Chemistry, 2014, 2014 (14), pp.2942-2955. ⟨10.1002/ejoc.201400090⟩

Article dans une revue istex hal-00994366v1
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Iodine(III)-mediated ethoxychlorination of enamides with iron(III) chloride

Sophie Nocquet-Thibault , Corinne Minard , Pascal Retailleau , Kevin Cariou , Robert H. Dodd

Tetrahedron, 2014, 70 (38), pp.6769-6775. ⟨10.1016/j.tet.2014.07.066⟩

Article dans une revue hal-01067773v1
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Transition-metal-free tunable chemoselective N functionalization of indoles with ynamides.

Alexandre Hentz , Pascal Retailleau , Vincent Gandon , Kevin Cariou , Robert H Dodd

Angewandte Chemie International Edition, 2014, 53 (32), pp.8333-8337. ⟨10.1002/anie.201402767⟩

Article dans une revue istex hal-01065687v1
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Iodine(III)-Mediated Umpolung of Bromide Salts for the Ethoxybromination of Enamides.

Sophie Nocquet-Thibault , Pascal Retailleau , Kevin Cariou , Robert H Dodd

Organic Letters, 2013, 15 (8), pp.1842-5. ⟨10.1021/ol400453b⟩

Article dans une revue hal-00827755v1
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Development of DANDYs, New 3,5-Diaryl-7-azaindoles Demonstrating Potent DYRK1A Kinase Inhibitory Activity.

Stéphanie Gourdain , Julien Dairou , Clément Denhez , Linh Chi Bui , Fernando Rodrigues-Lima et al.

Journal of Medicinal Chemistry, 2013, 56 (23), pp.9569-9585. ⟨10.1021/jm401049v⟩

Article dans une revue hal-00933939v1

New elements in the gold(I)-catalyzed cycloisomerization of enynyl ester derivatives embedding a cyclohexane template

Youssef Harrak , Malika Makhlouf , Stéphane Azzaro , Emily Mainetti , Juan Manuel Lopez Romero et al.

Journal of Organometallic Chemistry, 2011, 696 (1), pp.388-399. ⟨10.1016/j.jorganchem.2010.10.016⟩

Article dans une revue istex hal-05415359v1
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Copper(I) catalyzed regioselective asymmetric alkoxyamination of aryl enamide derivatives.

Masafumi Nakanishi , Corinne Minard , Pascal Retailleau , Kevin Cariou , Robert H Dodd

Organic Letters, 2011, 13 (21), pp.5792-5. ⟨10.1021/ol202367d⟩

Article dans une revue hal-00647697v1

Generation and Trapping of Cyclopentenylidene Gold Species: Four Pathways to Polycyclic Compounds

Gilles Lemière , Vincent Gandon , Kevin Cariou , Alexandra Hours , Takahide Fukuyama et al.

Journal of the American Chemical Society, 2009, 131 (8), pp.2993-3006. ⟨10.1021/ja808872u⟩

Article dans une revue hal-05415340v1

Tandem Gold(I)-Catalyzed Cyclization/Electrophilic Cyclopropanation of Vinyl Allenes

Gilles Lemière , Vincent Gandon , Kevin Cariou , Takahide Fukuyama , Anne-Lise Dhimane et al.

Organic Letters, 2007, 9 (11), pp.2207-2209. ⟨10.1021/ol070788r⟩

Article dans une revue hal-05415300v1
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New unsaturated amino acids containing an allylsilane moiety on the lateral chain

Gianna Reginato , Alessandro Mordini , Patrick Meffre , Alice Tenti , Michela Valacchi et al.

Tetrahedron: Asymmetry, 2006, 17 (6), pp.922-926. ⟨10.1016/j.tetasy.2006.02.017⟩

Article dans une revue hal-02002619v1