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Laurence Finot

Ingénieur d'étude à INRAE
54
Documents
Researcher identifiers

Presentation

Biologiste cellulaire de formation, j'ai soutenu une thèse de biologie et physiologie animale en février 2019. Je travaille à l’Institut National de la Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) dans l’équipe « Biologie des fonctions pour la transition des élevages» de l’UMR PEGASE de Saint Gilles. Ces dix dernières années, je me suis intéressée aux cellules souches adultes de la glande mammaire chez les ruminants laitiers à travers plusieurs projets collaboratifs. Mes travaux actuels se concentrent surtout sur le développement de modèles mammaires in vitro cultivés en 3D pour reproduire les alvéoles sécrétrices du lait et étudier les mécanismes mis en jeu pendant la lactation en s’affranchissant de l’expérimentation in vivo.

Research domains


Skills

biologie cellulaire cytométrie en flux histologie biologie moléculaire

Publications

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Post-milking application of a Lacticaseibacillus paracasei strain impacts bovine teat microbiota while preserving the mammary gland physiology and immunity

C Goetz , L Rault , J Cuffel , P Poton , L Finot
Beneficial Microbes, 2024, pp.1 - 17. ⟨10.1163/18762891-bja00014⟩
Journal articles hal-04581102v1
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Mammary gland 3D cell culture systems in farm animals

Laurence Finot , Eric Chanat , Frederic Dessauge
Veterinary Research, 2021, 52 (1), ⟨10.1186/s13567-021-00947-5⟩
Journal articles hal-03256473v1
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Genomic DNA PCR analysis to assess xenograft development in mouse mammary gland

Etienne Aujean , Johann Laubier , Nicolas Brun , Laurence Finot , Eric Chanat
Biotechniques, 2020, 68 (4), pp.219-222. ⟨10.2144/btn-2019-0125⟩
Journal articles hal-02467149v1

The cellular mechanisms underlying mammary tissue plasticity during lactation in ruminants

Marion Boutinaud , Lucile Herve , Hélène Quesnel , Vanessa Lollivier , Laurence Finot
Animal, 2019, 13 (S1), pp.s52-s64. ⟨10.1017/S1751731119000624⟩
Journal articles hal-02263857v1

Mammary epithelial cell lineage changes during cow’s life

Laurence Finot , Eric Chanat , Frederic Dessauge
Journal of Mammary Gland Biology and Neoplasia, 2019, 24 (2), pp.185-197. ⟨10.1007/s10911-019-09427-1⟩
Journal articles hal-02051588v1
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Molecular signature of the putative stem/progenitor cells committed to the development of the bovine mammary gland at puberty

Laurence Finot , Eric Chanat , Frederic Dessauge
Scientific Reports, 2018, 8, pp.16194. ⟨10.1038/s41598-018-34691-2⟩
Journal articles hal-01916892v1

Staphylococcus aureus Phenol-Soluble Modulins Impair Interleukin Expression in Bovine Mammary Epithelial Cells

Martine Deplanche , Ludmila Alekseeva , Ksenia Semenovskaya , Chih Lung Fu , Frederic Dessauge
Infection and Immunity, 2016, 84 (6), pp.1682-1692. ⟨10.1128/IAI.01330-15⟩
Journal articles hal-01454608v1
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Mammary epithelial cell hierarchy in the dairy cow throughout lactation

Marie-Hélène Perruchot , Magdalena Arevalo Turrubiarte , Florence Dufreneix , Laurence Finot , Vanessa Lollivier
Stem Cells and Development, 2016, 25 (19), pp.1407-1418. ⟨10.1089/scd.2016.0098⟩
Journal articles hal-02636214v1

Phenotypic and functional characterization of two bovine mammary epithelial cell lines in 2D and 3D models

Magdalena Arevalo Turrubiarte , Marie-Hélène Perruchot , Laurence Finot , Frederique Mayeur , Frederic Dessauge
American Journal of Physiology - Cell Physiology, 2016, 310 (5), pp.C348-C356. ⟨10.1152/ajpcell.00261.2015⟩
Journal articles hal-01455886v1
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Oestradiol enhances apoptosis in bovine mammary epithelial cells in vitro

Lucile Yart , Laurence Finot , Vanessa Lollivier , Frederic Dessauge
Journal of Dairy Research, 2013, 80 (1), pp.113-121. ⟨10.1017/S0022029912000714⟩
Journal articles hal-01210411v1

Changes in mammary secretory tissue during lactation in ovariectomized dairy cows

Lucile Yart , Vanessa Lollivier , Laurence Finot , Joëlle Dupont , Sandra Wiart
Steroids, 2013, 78 (10), pp.973-981. ⟨10.1016/j.steroids.2013.06.003⟩
Journal articles hal-01129764v1
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Unilateral once daily milking locally induces differential gene expression in both mammary tissue and milk epithelial cells revealing mammary remodeling

Marion Boutinaud , Laurent Galio , Vanessa Lollivier , Laurence Finot , Sandra Wiart-Letort Wiart
Physiological Genomics, 2013, 45 (20), pp.973-985. ⟨10.1152/physiolgenomics.00059.2013⟩
Journal articles hal-01004555v1

Ovariectomy improves lactation persistency in dairy cows

Lucile Yart , Frederic Dessauge , Laurence Finot , S. Barbey , Pierre-Guy Marnet
Journal of Dairy Science, 2012, 95 (7), pp.3794-3802. ⟨10.3168/jds.2011-5195⟩
Journal articles hal-00841090v1

Mammary cell activity and turnover in dairy cows treated with the prolactin-release inhibitor quinagolide and milked once daily O

Marion Boutinaud , Vanessa Lollivier , Laurence Finot , R.M. Bruckmaier , P. Lacasse
Journal of Dairy Science, 2012, 95 (1), pp.177-187. ⟨10.3168/jds.2011-4461⟩
Journal articles hal-00926557v1

Suppression of ovarian secretions before puberty strongly affects mammogenesis in the goat

Lucile Yart , Laurence Finot , Pierre-Guy Marnet , Frederic Dessauge
Journal of Dairy Research, 2012, 79 (2), pp.157-167. ⟨10.1017/S0022029912000106⟩
Journal articles hal-00841091v1

Reference gene selection for quantitative real-time PCR normalization: Application in the caprine mammary gland

Laurence Finot , Pierre-Guy Marnet , Frederic Dessauge
Small Ruminant Research, 2011, 95 (1), pp.20-26. ⟨10.1016/j.smallrumres.2010.08.008⟩
Journal articles hal-00729325v1

Effects of nutrient restriction on mammary cell turnover and mammary gland remodeling in lactating dairy cows.

Frederic Dessauge , Vanessa Lollivier , B. Ponchon , R. Bruckmaier , Laurence Finot
Journal of Dairy Science, 2011, 94 (9), pp.4623-35. ⟨10.3168/jds.2010-4012⟩
Journal articles hal-00729290v1

Effects of ovariectomy in prebubertal goats

Frederic Dessauge , Laurence Finot , Sandra Wiart-Letort Wiart , Jean Marc Aubry , S.E. Ellis
Journal of Physiology and Pharmacology, 2009, 60, pp.127-133
Journal articles hal-02662849v1

Cell junction disruption after 36h milk accumulation was associated with changes in mammary secretory tissue activity ans dynamics in lactating dairy goats

Hedi Ben Chedly , P. Lacasse , Pierre-Guy Marnet , S. Wiart-Letort , Laurence Finot
Journal of Physiology and Pharmacology, 2009, 60, pp.105-111
Journal articles hal-00730137v1

Cell junction disruption after 36h milk accumulation was associated with changes in mammary secretory tissue activity and dynamics in lactating dairy goats

Hedi Ben Chedly , Pierre Lacasse , Pierre-Guy Marnet , Sandra Wiart-Letort , Laurence Finot
Journal of Physiology and Pharmacology, 2009, 60 (Supplement 3), pp.105-111
Journal articles hal-02660783v1

Dynamics of estrogen receptor-mediated transcriptional activation of responsive genes in vivo: apprehending transcription in four dimensions.

Raphaël Métivier , Guillaume Huet , Rozenn Gallais , Laurence Finot , Fabien Petit
Advances in Experimental Medicine and Biology, 2008, Advances in experimental medicine and biology - Vol 617, 617, pp.129-38. ⟨10.1007/978-0-387-69080-3_12⟩
Journal articles hal-00277827v1

Deoxyribonucleic acid methyl transferases 3a and 3b associate with the nuclear orphan receptor COUP-TFI during gene activation.

Rozenn Gallais , Florence Demay , Peter Barath , Laurence Finot , Renata Z. Jurkowska
Molecular Endocrinology -Baltimore-, 2007, 21 (9), pp.2085-98. ⟨10.1210/me.2006-0490⟩
Journal articles hal-00179636v1
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Appréhender le fonctionnement de la glande mammaire chez le bovin par le typage des cellules en microscopie

Laurence Finot , Eric Chanat
11. Journées du réseau des microscopistes INRAE, Nov 2022, Rennes, France
Conference papers hal-03875310v1
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A comparative study of stem-like cells in colostrum and milk of farm animals

Laurence Finot , Eric Chanat , Marion Boutinaud , Hélène Quesnel
International scientific meeting on colostrum, Nov 2022, Las Palmas, Spain
Conference papers hal-03875307v1
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Caractérisation du lignage épithélial de la glande mammaire bovine

Laurence Finot , Eric Chanat , Marie-Hélène Perruchot , Florence Dufreneix , Frederic Dessauge
23.Congrès de l'association francaise de cytométrie, Sep 2019, Rennes, France
Conference papers hal-02299629v1

Species-specific genomic DNA PCR analysis allows to assess the graft development in mouse xenotransplanted mammary gland

Etienne Aujean , Johann Laubier , Nicolas Brun , Laurence Finot , Eric Chanat
XVIIIe journée transversalité Glande Mammaire Lait (GML), Nov 2019, Paris, France
Conference papers hal-02375174v1

La cytométrie en flux : une approche pertinente pour l’étude des cellules épithéliales mammaires bovines

Laurence Finot , Eric Chanat , Marion Boutinaud , Sergine Even , Pierre Germon
XVIIIe journée transversalité Glande Mammaire Lait (GML), Nov 2019, Paris, France
Conference papers hal-02375171v1
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The cellular mechanisms underlying mammary tissue plasticity during lactation

Marion Boutinaud , Lucile Herve , Hélène Quesnel , Vanessa Lollivier , Laurence Finot
International Workshop on the Biology of Lactation in Farm Animals (Bolfa), Aug 2018, Dubrovnik, Croatia
Conference papers hal-01948627v1

[i]Staphylococcus aureus[/i] phenol-soluble modulins impair interleukin expression in bovine mammary epithelial cells.

Martine Deplanche , Liudmila Alekseeva , Ksenia Semenovskaya , Chih-Lung Fu , Frederic Dessauge
Journées d'Animation Scientifique du Département Santé Animale, Institut National de Recherche Agronomique (INRA). UMR Infectiologie et Santé Publique (1282)., May 2016, Poitiers, France
Conference papers hal-01352689v1

Comparison of different tissue dissociation methods to determine mammary cell fate in lactating cows by flow cytometry

Magdalena Arevalo Turrubiarte , Marie-Hélène Perruchot , Vanessa Lollivier , Laurence Finot , Frederique Mayeur
Gordon Research Conference on Mammary Gland Biology, Jun 2014, Lucca, Italy
Conference papers hal-01210729v1

Effect of ovariectomy on lactation persistency and mammary gland activity in dairy cows

L. Yart , Frederic Dessauge , Laurence Finot , S. Barbey , Pierre-Guy Marnet
7th International Conference on Farm Animal Endocrinology, 2011, Bern (CH), Switzerland
Conference papers hal-00841086v1

Lactation persistency and mammary gland activity in ovariectomized dairy cows

L. Yart , Vanessa Lollivier , Laurence Finot , S. Barbey , Pierre-Guy Marnet
7th international congress on farm animal endocrinology, Aug 2011, Bern, Switzerland
Conference papers hal-00841080v1

Effect of ovariectomy on lactation persistency and mammary gland activity in dairy cows

Lucile Yart , Frederic Dessauge , Laurence Finot , Sarah Barbey , Pierre-Guy Marnet
7. International Congress on Farm Animal Endocrinology (ICFAE), Aug 2011, Bern, Switzerland
Conference papers hal-02803816v1

Effects of early ovariectomy on caprine mammary gland parenchyma during prepuberty

Laurence Finot , Lucile Yart , Frederic Dessauge
JAM 2010 : Joint Annual Meeting, Jul 2010, Denver, United States
Conference papers hal-02751677v1

Chronic inhibition of prolactin discharge at milking affects mammary cell activity and turnover in dairy cows

Vanessa Lollivier , Christine Péchoux , Sandra Wiart-Letort Wiart , Laurence Finot , Rupert Bruckmaier
6. International Symposium for Young Scientist (ISYS) "Human and Animal Development: Regulatory Mechanisms", Sep 2008, Lublin, Poland
Conference papers hal-02755950v1

Tight junction opening after 36h milk accumulation was associated to a change in mammary secretory tissue activity and dynamics in lactating dairy goats

Hedi Ben Chedly , Pierre Lacasse , Pierre-Guy Marnet , Sandra Wiart-Letort , Laurence Finot
6. International Symposium for Young Scientist (ISYS)"Human and Animal Development: regulatory mechanisms", Sep 2008, Lublin, Poland
Conference papers hal-02758399v1

Effects of ovariectomy in prepubertal goats

Frederic Dessauge , Laurence Finot , Sandra Wiart-Letort Wiart , Jean Marc Aubry
6. International Symposium for Young Scientists (ISYS) "Human and Animal Development: Regulatory Mechanisms, Sep 2008, Lublin, Poland
Conference papers hal-02754048v1

Tight junction opening after 36h milk accumulation was associated to a change in mammary secretory tissue activity and dynamics in lactating dairy goats

Hedi Ben Chedly , P. Lacasse , Pierre-Guy Marnet , S. Wiart-Letort , Laurence Finot
6th International Symposium for Young Scientist (ISYS)"Human and Animal Development: regulatory mechanisms", Sep 2008, Lublin (POL), Poland. 14 p
Conference papers hal-00729820v1

Dynamics of ER-mediated Transcriptional Activation of Responsive Genes In vivo: Apprehending Transcription in Four Dimensions.

Raphaël Métivier , Guillaume Huet , Rozenn Gallais , Laurence Finot , Fabien Petit
V th International Symposium on Hormonal Carcinogenesis, Sep 2006, Montpellier, France
Conference papers hal-00493884v1

Caractérisation des éléments cellulaires des sécrétions lactées transférables de la mère à la progéniture chez la vache, la chèvre et la truie

Laurence Finot , Eric Chanat , Fabienne Le Provost , Anne Burtey , Marion Boutinaud
Journées d'animation scientifique du département Phase, May 2022, Poitiers, France. pp.68, Résumés des crédits incitatifs - JAS 2022
Conference poster hal-03716605v1

Validation de la transplantation hétérologue pour la caractérisation des cellules souches mammaires bovines

Laurence Finot , Fabienne Le Provost , Catherine Hue-Beauvais , Etienne Aujean , Frederic Dessauge
Journées d'animation scientifique du département Phase, May 2022, Poitiers, France. pp.69, Résumés des crédits incitatifs - JAS 2022
Conference poster hal-03716640v1
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Implication des cellules souches adultes et des cellules progénitrices dans le développement épithélial mammaire à la puberté

Laurence Finot , Catherine Hue-Beauvais , Etienne Aujean , Fabienne Le Provost , Eric Chanat
Stem-Phase. Première rencontre du réseau Phase sur les cellules souches, Jan 2019, Bron, France. 2019
Conference poster hal-02786407v1

Validation de la transplantation hétérologue pour la caractérisation des cellules souches mammaires bovines

Laurence Finot , Fabienne Le Provost , Catherine Hue-Beauvais , Etienne Aujean , Eric Chanat
Journées d'Animation Scientifique du département Phase (JAS Phase 2018), Apr 2018, Rennes, France. , 2018, Journées d’animation scientifiques du département Phase - Recueil des résumés
Conference poster hal-02736191v1
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Delineating the MaSC/progenitors committed to the development in the bovine mammary gland at puberty

Laurence Finot , Catherine Hue-Beauvais , Etienne Aujean , Fabienne Le Provost , Eric Chanat
Mammary Gland Biology Gordon Conference, May 2018, Barga, Italy. 2018
Conference poster hal-02791174v1
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Study of the mammary stem cells / progenitors committed to the development of the bovine mammary gland

Laurence Finot , Eric Chanat , Frederic Dessauge
69. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2018, Dubrovnik, Croatia. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 24, 2018, Annual Meeting of the European Association for Animal Production
Conference poster hal-01872292v1

Caractérisation de biomarqueurs cellulaires pour étudier la plasticité mammaire au cours de la lactation chez la vache laitière

Marie-Hélène Perruchot , Florence Dufreneix , Laurence Finot , Frederique Mayeur , Frederic Dessauge
Journées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase 2016), Apr 2016, Tours, France. , 115 p., 2016, Crédits incitatifs financés entre 2011 et 2014
Conference poster hal-02742866v1

Phenol-soluble modulins alpha induce G2/M phase transition delay and impair immune response of eukaryotic cells

Martine Deplanche , Rachid El-Aouar Filho , Ksenia Semenovskaya , Liudmila Alekseeva , Julien Jardin
ICI 2016 International Congress of Immunology, Aug 2016, Melbourne, Australia. John Wiley and Sons, European Journal of Immunology, 46 Supplement: 1 Special Issue: SI Meeting Abstract: 1425, pp.1: 351, 2016, European Journal of Immunology
Conference poster hal-01389063v1

Staphylococcus aureus phenol-soluble modulins impair interleukin expression in bovine mammary epithelial cells

Martine Deplanche , Liudmila Alekseeva , Ksenia Semenovskaya , Chih-Lung Fu , Frederic Dessauge
Journées d'Animation Scientifique du Département Santé Animale, May 2016, Chasseneuil-du-Poitou, France. 98 p., 2016
Conference poster hal-01454659v1

S. aureus and E. coli induce IL-32 gene expression to different extents during infection of bovine mammary gland epithelial cells

Martine Deplanche , L. Alexeeva , Pierre Germon , Pascal Rainard , Frederic Dessauge
4. European Congress of Immunology, Sep 2015, Vienne, Austria. , 2015, Abstract book
Conference poster hal-01454530v1

Exfoliation of mammary epithelial cells in milk is linked with lactation persistency in dairy cows

Marion Boutinaud , Lucile Yart , Perrine Poton , Sandra Wiart , Laurence Finot
64. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2013, Nantes, France. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 64, 2013, Annual Meeting of the European Association for Animal Production
Conference poster hal-01210534v1

Effect of ovariectomy on milk yield and mammary gland activity in lactating cow

Lucile Yart , Frederic Dessauge , Laurence Finot , Sandra Wiart , Arnaud Mottin
ADSA/ASAS Joint Annual Meeting, Jul 2012, Phoenix, United States. ASAS - American Society of Animal Science, Journal of Animal Science, 90 (Suppl. 3), 2012, Journal of Animal Science
Conference poster hal-01210626v1
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Effects of high feeding level on caprine mammary gland development and milk yield potential

Jean Marc Aubry , Laurence Finot , Sandra Wiart , Lucile Yart , Eric Siroux
ADSA/ASAS Joint Annual Meeting, Jul 2012, Phoenix, United States. ASAS - American Society of Animal Science, Journal of Animal Science, 90 (Suppl. 3), 2012, Journal of Animal Science
Conference poster hal-01210627v1

Estradiol enhances apoptosis in bovine mammary epithelial cells in vitro

Lucile Yart , Laurence Finot , Vanessa Lollivier , Pierre-Guy Marnet , Frederic Dessauge
ADSA/ASAS Joint Annual Meeting, Jul 2012, Phoenix, United States. ASAS - American Society of Animal Science, Journal of Animal Science, 90 (Suppl. 3), 2012, Journal of Animal Science
Conference poster hal-01210629v1