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LAURIE GALVAN

Je suis enseignante-chercheuse en neurosciences à l'Université de Nîmes. Ma thématique de recherche porte sur la dysfonction de la communication neuronale dans les troubles du spectre autistique.
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Domaines de recherche

Neurosciences [q-bio.NC]

Compétences

electrophysiology autism huntington's disease striatum motor deficit

Publications

Editorial: New insight into Huntington's disease: From neuropathology to possible therapeutic targets

Ana María Estrada-Sánchez , George Rebec , Laurie Galvan
Frontiers in Neuroscience, 2023, 17, ⟨10.3389/fnins.2023.1138712⟩
Article dans une revue hal-04434314v1
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Age‐related behavioural and striatal dysfunctions in Shank3 ΔC/ΔC mouse model of autism spectrum disorder

Mathieu Thabault , Valentine Turpin , Éric Balado , Cloé Fernandes-Gomes , Anne‐lise Huot
European Journal of Neuroscience, 2023, 57 (4), pp.607-618. ⟨10.1111/ejn.15919⟩
Article dans une revue hal-04028962v1
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Major motor and gait deficits with sexual dimorphism in a Shank3 mutant mouse model

Emmanuel Matas , Alexandre Maisterrena , Mathieu Thabault , Eric Balado , Maureen Francheteau
Molecular Autism, 2021, 12 (1), pp.2. ⟨10.1186/s13229-020-00412-8⟩
Article dans une revue hal-03150112v1

Striatal GABA ergic interneuron dysfunction in the Q175 mouse model of Huntington's disease

Sandra Holley , Laurie Galvan , Talia Kamdjou , Carlos Cepeda , Michael Levine
European Journal of Neuroscience, 2018, ⟨10.1111/ejn.14283⟩
Article dans une revue hal-02459725v1
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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Laurie Galvan , Laetitia Francelle , Marie-Claude Gaillard , Lucie de Longprez , Maria-Angeles Carrillo-de Sauvage
Brain - A Journal of Neurology , 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Article dans une revue hal-02074093v1
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CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease

Lydie Boussicault , Sandro Alves , Antonin Lamazière , Anabelle Planques , Nicolas Heck
Brain - A Journal of Neurology , 2016, 139 (3), pp.953-970. ⟨10.1093/brain/awv384⟩
Article dans une revue hal-01299208v1

JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse

Jamee m. Berg , Changhoon Lee , Leslie Chen , Laurie Galvan , Carlos Cepeda
Neuron, 2015, 88 (6), pp.1173-1191. ⟨10.1016/j.neuron.2015.10.031⟩
Article dans une revue hal-02459747v1

The striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo

Laetitia Francelle , Laurie Galvan , Marie-Claude Gaillard , Fanny Petit , Benoit Bernay
Neurobiology of Aging, 2015, 36 (3), pp.1601.e7-1601.e16. ⟨10.1016/j.neurobiolaging.2014.11.014⟩
Article dans une revue hal-02459770v1

Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.

Laetitia Francelle , Laurie Galvan , Marie-Claude Gaillard , Fanny Petit , Benoît Bernay
Neurobiology of Aging, 2015, pp.1601.e7-16. ⟨10.1016/j.neurobiolaging.2014.11.014⟩
Article dans une revue hal-01465910v1

Enhanced GABAergic Inputs Contribute to Functional Alterations of Cholinergic Interneurons in the R6/2 Mouse Model of Huntington’s Disease

Sandra Holley , Prasad Joshi , Anna Parievsky , Laurie Galvan , Jane Chen
eNeuro, 2015, 2 (1), pp.ENEURO.0008-14.2015. ⟨10.1523/ENEURO.0008-14.2015⟩
Article dans une revue hal-02459736v1

Enhanced GABAergic Inputs Contribute to Functional Alterations of Cholinergic Interneurons in the R6/2 Mouse Model of Huntington’s Disease

Sandra Holley , Prasad Joshi , Anna Parievsky , Laurie Galvan , Jane Chen
eNeuro, 2015, 2 (1), pp.ENEURO.0008-14.2015. ⟨10.1523/ENEURO.0008-14.2015⟩
Article dans une revue hal-02459863v1
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Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's disease

Laetitia Francelle , Laurie Galvan , Emmanuel Brouillet
Frontiers in Cellular Neuroscience, 2014, ⟨10.3389/fncel.2014.00295⟩
Article dans une revue hal-02459873v1

Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease

Jane Chen , Elizabeth Wang , Laurie Galvan , My Huynh , Prasad Joshi
Article dans une revue hal-02459786v1

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

Maria Damiano , Elsa Diguet , Carole Malgorn , Marilena d'Aurelio , Laurie Galvan
Human Molecular Genetics, 2013, 22 (19), pp.3869-3882. ⟨10.1093/hmg/ddt242⟩
Article dans une revue hal-02459752v1

Functional Differences Between Direct and Indirect Striatal Output Pathways in Huntington's Disease

Laurie Galvan , Elizabeth Wang , Carlos Cepeda , Michael Levine
Journal of Huntington's Disease, 2012, 1 (1), pp.17-25. ⟨10.3233/JHD-2012-120009⟩
Article dans une revue hal-02459788v1

Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo

Laurie Galvan , Nad'A Lepejová , Marie-Claude Gaillard , Carole Malgorn , Martine Guillermier
Neurobiology of Aging, 2012, 33 (8), pp.1845.e5-1845.e6. ⟨10.1016/j.neurobiolaging.2012.01.009⟩
Article dans une revue hal-02459764v1

Mitochondria in Huntington's disease

Maria Damiano , Laurie Galvan , Nicole Déglon , Emmanuel Brouillet
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2010, 1802 (1), pp.52-61. ⟨10.1016/j.bbadis.2009.07.012⟩
Article dans une revue hal-02459756v1

Behavioral phenotyping of heterozygous acetylcholinesterase knockout (AChE+/−) mice showed no memory enhancement but hyposensitivity to amnesic drugs

Julie Espallergues , Laurie Galvan , Florence Sabatier , Vanessa Rana-Poussine , Tangui Tm Maurice
Behavioural Brain Research, 2010, 206 (2), pp.263-273. ⟨10.1016/j.bbr.2009.09.024⟩
Article dans une revue hal-02459760v1
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Mitochondria in Huntington's disease

Maria Damiano , Laurie Galvan , Nicole Déglon , Emmanuel Brouillet
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2009, 1802 (1), pp.52. ⟨10.1016/j.bbadis.2009.07.012⟩
Article dans une revue hal-00543005v1

Hyposensitivity to the amnesic effects of scopolamine or amyloid β25–35 peptide in heterozygous acetylcholinesterase knockout (AChE+/−) mice

Julie Espallergues , Laurie Galvan , Laurence Lepourry , Béatrice Bonafos , Tangui Tm Maurice
Chemico-Biological Interactions, 2008, 175 (1-3), pp.131-134. ⟨10.1016/j.cbi.2008.04.001⟩
Article dans une revue hal-02459753v1

Somatostatin interneurons contribute towards increased striatal inhibition in the Q175 mouse model of Huntington's Disease

S. M. Holley , Laurie Galvan , Talia Kamdjou , C. Cepeda , M. S. Levine
46th annual meeting, neuroscientists SFN 2016, Nov 2016, SAN DIEGO, United States
Communication dans un congrès hal-02534718v1

Altered function of Parvalbumin expressing interneurons in mouse models of Huntington’s disease

Laurie Galvan , S. M. Holley , C. Cepeda , M. S. Levine
SFN 2016, Nov 2016, SAN DIEGO, United States
Communication dans un congrès hal-02534713v1

Synaptic alterations in the striatum and the cortex of a new mouse model of autism spectrum disorders: JAKMIP1 knock-out mouse

Laurie Galvan , J. Berg , J y Chen , C Cepeda , D Geschwind
SFN 2015, Oct 2015, CHICAGO, United States
Communication dans un congrès hal-02534707v1

Characterization of the striatal kinase Dclk3 and its neuroprotective effects against mutant huntingtin

E. Brouillet , L. Francelle , Laurie Galvan , M.-C Gaillard , M.-A Carrillo-de Sauvage
SFN 2015, Oct 2015, CHICAGO, United States
Communication dans un congrès hal-02534708v1

Optogenetics reveal alterations in dopamine neurotransmission in the YAC128 mouse model of Huntington’s disease

J y Chen , G K Akopian , C J Wang , Laurie Galvan , V M André
SFN 2014, Nov 2014, WASHINGTON,dc, United States
Communication dans un congrès hal-02534701v1

The newly identified striatal marker Doublecortin-like kinase 3 (Dclk3) may be a molecular determinant of striatal vulnerability in Huntington’s disease

L. Francelle , Laurie Galvan , M.-C Gaillard , G. Liot , M de Chaldée d'Abbas
SFN 2013, Nov 2013, SAN DIEGO, United States
Communication dans un congrès hal-02534692v1

2010001M06rik (St102) protects striatal neurons against an N-terminal fragment of mutant huntingtin in vivo

E. Brouillet , Laurie Galvan , M.-C Gaillard , N Lepejovà , F Petit
SFN 2012, Oct 2012, NEW ORLEANS, United States
Communication dans un congrès hal-02534682v1

Doublecortin-like kinase 3 (DCLK3), a novel striatum-enriched species, is a modulator of mutant huntingtin in vivo

Laurie Galvan , M.-C Gaillard , M. de Chaldee , G. Auregan , N. Dufour
SFN 2009, Oct 2009, CHICAGO, United States
Communication dans un congrès hal-02534671v1

Doublecortin-like kinase 3 (DCLK3), a novel striatum-enriched species, is a modulator of mutant huntingtin in vivo

Laurie Galvan , Galvan L. , Gaillard M.-C. , Chaldée M. De , Auregan G.
SFN 2009, Oct 2009, CHICAGO, United States
Communication dans un congrès hal-02545451v1

Optogenetic Control of Parvalbumin-Expressing Interneurons in the R6/2 Mouse Model of Huntington’s disease”

Laurie Galvan , Carlos Cepeda , Michael s. Levine
CAG Triplet Repeat Disorders - Gordon Research Conferences, Jun 2013, waterville valley, NH, United States
Poster de conférence hal-02534733v1