LB

Lionel Ballut

61%
Libre accès
38
Documents
Contact

Présentation

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Biochimie Biologie structurale Enzymologie

Publications

Publications

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Biochemical, Bioinformatic, and Structural Comparisons of Transketolases and Position of Human Transketolase in the Enzyme Evolution

Rainier-Numa Georges , Lionel Ballut , Nushin Aghajari , Laurence Hecquet , Franck Charmantray et al.
Article dans une revue hal-04582902 v1

Specifically Targeting Metacaspases of Candida: A New Therapeutic Opportunity

Anne-Lise Bienvenu , Lionel Ballut , Stephane Picot
Journal of Fungi, 2024, 10 (2), pp.90. ⟨10.3390/jof10020090⟩
Article dans une revue hal-04707277 v1

Structural and Functional Integration of Tissue-Nonspecific Alkaline Phosphatase Within the Alkaline Phosphatase Superfamily: Evolutionary Insights and Functional Implications

Iliass Imam , Gilles Rautureau , Sébastien Violot , Eva Drevet Mulard , David Magne et al.
Metabolites, 2024, 14 (12), pp.659. ⟨10.3390/metabo14120659⟩
Article dans une revue hal-04988962 v1
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Structural determination and kinetic analysis of the Transketolase from Vibrio vulnificus reveal unexpected cooperative behavior

Rainier‐numa Georges , Lionel Ballut , Guillaume Octobre , Arnaud Comte , Laurence Hecquet et al.
Protein Science, In press, 33 (3), pp.e4884. ⟨10.1002/pro.4884⟩
Article dans une revue hal-04409850 v1

GMP Synthetase: Allostery, Structure, and Function

Lionel Ballut , Sébastien Violot , Sanjeev Kumar , Nushin Aghajari , Hemalatha Balaram
Biomolecules, 2023, 13 (9), pp.1379. ⟨10.3390/biom13091379⟩
Article dans une revue hal-04285650 v1
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Purine containing carbonucleoside phosphonate analogues as novel chemotype for Plasmodium falciparum Inhibition

Bemba Sidi Mohamed , Minh Chau Nguyen , Sharon Wein , Jean-Pierre Uttaro , Xavier Robert et al.
European Journal of Medicinal Chemistry, 2023, 258, pp.115581. ⟨10.1016/j.ejmech.2023.115581⟩
Article dans une revue hal-04269850 v1
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Scaffolding Protein GspB/OutB Facilitates Assembly of the Dickeya dadantii Type 2 Secretion System by Anchoring the Outer Membrane Secretin Pore to the Inner Membrane and to the Peptidoglycan Cell Wall

Shiheng Zhang , Shuang Gu , Piers Rycroft , Florence Ruaudel , Frédéric Delolme et al.
mBio, 2022, 13 (3), pp.e0025322. ⟨10.1128/mbio.00253-22⟩
Article dans une revue hal-03748109 v2

The Candida glabrata glycogen branching enzyme structure reveals unique features of branching enzymes of the Saccharomycetaceae phylum

Léa Conchou , Juliette Martin , Isabelle R Gonçalves , Frédéric Galisson , Sébastien Violot et al.
Glycobiology, 2022, 32 (4), pp.343-355. ⟨10.1093/glycob/cwab110⟩
Article dans une revue hal-03539601 v1
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The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding

Cecilia Rocchi , Camille Louvat , Adriana Miele , Julien Batisse , Christophe Guillon et al.
International Journal of Molecular Sciences, 2022, 23 (22), pp.13742. ⟨10.3390/ijms232213742⟩
Article dans une revue hal-03434126 v1
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Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis

Lionel Ballut , Sébastien Violot , Frédéric Galisson , Isabelle R Gonçalves , Juliette Martin et al.
Biomolecules, 2022, 12 (7), pp.871. ⟨10.3390/biom12070871⟩
Article dans une revue hal-03708048 v1
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Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium

Léa Conchou , Bastien Doumèche , Frédéric Galisson , Sébastien Violot , Chloé Dugelay et al.
Communications Biology, 2022, 5 (1), pp.1158. ⟨10.1038/s42003-022-04091-4⟩
Article dans une revue hal-04285661 v1

Exploring molecular determinants of polysaccharide lyase family 6–1 enzyme activity

Sébastien Violot , Frédéric Galisson , Loïc Carrique , Vinesh Jugnarain , Léa Conchou et al.
Glycobiology, 2021, 31 (11), pp.1557-1570. ⟨10.1093/glycob/cwab073⟩
Article dans une revue hal-04962311 v1
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Structure–function analysis of pectate lyase Pel3 reveals essential facets of protein recognition by the bacterial type 2 secretion system.

Camille Pineau , Natalia Guschinskaya , Isabelle R Gonçalves , Florence Ruaudel , Xavier Robert et al.
Journal of Biological Chemistry, 2021, pp.100305. ⟨10.1016/j.jbc.2021.100305⟩
Article dans une revue hal-03143879 v1
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Exploring molecular determinants of polysaccharide lyase family 6–1 enzyme activity

Sébastien Violot , Frédéric Galisson , Loïc Carrique , Vinesh Jugnarain , Léa Conchou et al.
Glycobiology, 2021, ⟨10.1093/glycob/cwab073⟩
Article dans une revue hal-03379698 v1
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Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase

Loïc Carrique , Lionel Ballut , Arpit Shukla , Neelakshi Varma , Resmi Ravi et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-17013-x⟩
Article dans une revue hal-03094406 v1

Helices on Interdomain Interface Couple Catalysis in the ATPPase Domain with Allostery in Plasmodium falciparum GMP Synthetase

Santosh Shivakumaraswamy , Nivedita Pandey , Lionel Ballut , Sébastien Violot , Nushin Aghajari et al.
ChemBioChem, 2020, 21 (19), pp.2805-2817. ⟨10.1002/cbic.202000158⟩
Article dans une revue (article de synthèse) hal-04913889 v1

Helices on Interdomain Interface Couple Catalysis in the ATPPase Domain with Allostery in Plasmodium falciparum GMP Synthetase

Santosh Shivakumaraswamy , Nivedita Pandey , Lionel Ballut , Sébastien Violot , Nushin Aghajari et al.
ChemBioChem, 2020, 21 (19), pp.2805-2817. ⟨10.1002/cbic.202000158⟩
Article dans une revue hal-03094412 v1

Structural determinants increasing flexibility confer cold adaptation in psychrophilic phosphoglycerate kinase.

David Mandelman , Lionel Ballut , David Wolff , Georges Feller , Charles Gerday et al.
Extremophiles, 2019
Article dans une revue hal-02412726 v1

Structural determinants increasing flexibility confer cold adaptation in psychrophilic phosphoglycerate kinase

David Mandelman , Lionel Ballut , David Wolff , Georges Feller , Charles Gerday et al.
Extremophiles, 2019, 23 (5), pp.495-506. ⟨10.1007/s00792-019-01102-x⟩
Article dans une revue hal-03094420 v1

Exon Junction Complexes can have distinct functional flavours to regulate specific splicing events

Zhen Wang , Lionel Ballut , Isabelle Barbosa , Hervé Le Hir
Scientific Reports, 2018, 8 (1), pp.9509. ⟨10.1038/s41598-018-27826-y⟩
Article dans une revue hal-04988943 v1

Mechanism of allostery and catalysis in P. falciparum GMP Synthetase

Santosh Shivakumaraswamy , Lionel Ballut , Sebastien Violot , Lakshmi Prasoona Thota , Bauke Dijkstra et al.
Acta Crystallographica Section A : Foundations and Advances [2014-..], 2017, 73 (a2), pp.C248-C248. ⟨10.1107/S2053273317093251⟩
Article dans une revue hal-04988939 v1

Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria

Hien-Anh Nguyen , Takla El Khoury , Sébastien Guiral , Maria-Halima Laaberki , Marie-Pierre Candusso et al.
Journal of Molecular Biology, 2017, 429 (20), pp.3056 - 3074. ⟨10.1016/j.jmb.2017.08.016⟩
Article dans une revue hal-01680740 v1
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Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system.

Thomas Koelblen , Célia Bergé , Mickaël V Cherrier , Karl Brillet , Luisa Jimenez-Soto et al.
FEBS Journal, 2017, 284 (23), pp.4143-4157. ⟨10.1111/febs.14299⟩
Article dans une revue hal-04295943 v1
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Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation

Lionel Ballut , Sébastien Violot , Santosh Shivakumaraswamy , Lakshmi Prasoona Thota , Manu Sathya et al.
Nature Communications, 2015, 6 (1), ⟨10.1038/ncomms9930⟩
Article dans une revue hal-03094522 v1

Substrate recognition by the bacterial type II secretion system: more than a simple interaction

C. Pineau , Natalia Guschinskaya , X. Robert , P. Gouet , L. Ballut et al.
Molecular Microbiology, 2014, 94 (1), pp.126-40. ⟨10.1111/mmi.12744⟩
Article dans une revue hal-02001308 v1

Mapping of heparin/heparan sulfate binding sites on αvβ3 integrin by molecular docking

Lionel Ballut , N. Sapay , E. Chautard , A. Imberty , S. Ricard-Blum
J. Mol. Recognit., 2013, pp.76-85
Article dans une revue hal-00787594 v1

Surface characterization and efficiency of a matrix-free and flat carboxylated gold sensor chip for surface plasmon resonance (SPR)

L. Roussille , G. Brotons , Lionel Ballut , G. Louarn , D. Ausserre et al.
Analytical and Bioanalytical Chemistry, 2011, 401 (5), pp.1601-1617. ⟨10.1007/s00216-011-5220-z⟩
Article dans une revue istex hal-00849709 v1

MatrixDB, the extracellular matrix interaction database.

Emilie Chautard , Marie Fatoux-Ardore , Lionel Ballut , Nicolas Thierry-Mieg , Sylvie Ricard-Blum
Nucleic Acids Research, 2011, 39 (Database issue), pp.D235-40. ⟨10.1093/nar/gkq830⟩
Article dans une revue hal-00807349 v1

Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells

Clément Faye , Antonio Inforzato , Marine Bignon , Daniel j. Hartmann , Laurent Muller et al.
Biochemical Journal, 2010, 427 (3), pp.467-475. ⟨10.1042/BJ20091594⟩
Article dans une revue hal-02163706 v1
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Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells

Clément Faye , Antonio Inforzato , Marine Bignon , Daniel Hartmann , Laurent Muller et al.
Biochemical Journal, 2010, 427 (3), pp.467-475. ⟨10.1042/BJ20091594⟩
Article dans une revue hal-00479272 v1

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

Hala Chamieh , Lionel Ballut , Fabien Bonneau , Hervé Le Hir
Nature Structural and Molecular Biology, 2007, 15 (1), pp.85-93. ⟨10.1038/nsmb1330⟩
Article dans une revue hal-04988921 v1

Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.

Christian B F Andersen , Lionel Ballut , Jesper S Johansen , Hala Chamieh , Klaus H Nielsen et al.
Science, 2006, 313 (5795), pp.1968-72. ⟨10.1126/science.1131981⟩
Article dans une revue hal-00168014 v1

HcPro, a multifunctional protein encoded by a plant RNA virus, targets the 20S proteasome and affects its enzymic activities

Lionel Ballut , Martin Drucker , Martine Pugnière , Florence Cambon , Stéphane Blanc et al.
Journal of General Virology, 2005, 86, pp.2595-2603. ⟨10.1099/vir.0.81107-0⟩
Article dans une revue hal-01189228 v1

The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.

Lionel Ballut , Brice Marchadier , Aurélie Baguet , Catherine Tomasetto , Bertrand Séraphin et al.
Nature Structural and Molecular Biology, 2005, 12 (10), pp.861-9. ⟨10.1038/nsmb990⟩
Article dans une revue istex hal-00187421 v1

Biochemical identification of proteasome-associated endonuclease activity in sunflower

Lionel Ballut , F. F. Petit , S. S. Mouzeyar , Olivier Le Gall , Thierry Candresse et al.
BBA - Biochimica et Biophysica Acta, 2003, 1645, pp.30-39. ⟨10.1016/S1570-9639(02)00500-9⟩
Article dans une revue istex hal-00964401 v1