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Probing Enzymatic PET Degradation: Molecular Dynamics Analysis of Cutinase Adsorption and Stability
Mehdi Sahihi
,
Pierre Fayon
,
Lionel Nauton
,
Florent Goujon
,
Julien Devémy
et al.
Article dans une revue
hal-04600374
v1
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Synthesis and Kinase Inhibitory Potencies of Pyrazolo[3,4-g]Isoquinolines
Mathilde Defois
,
Chloé Rémondin
,
Béatrice Josselin
,
Lionel Nauton
,
Vincent Théry
et al.
Article dans une revue
hal-03765284
v1
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1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors
Laurent Gavara
,
Federica Verdirosa
,
Laurent Sevaille
,
Alice Legru
,
Giuseppina Corsica
et al.
Article dans une revue
hal-03767295
v1
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Cleavage of Aliphatic α-Hydroxy Ketones by Evolved Transketolase from Geobacillus stearothermophilus
Hubert Casajus
,
Aurélie Lagarde
,
Lionel Nauton
,
Nazim Ocal
,
Martin Leremboure
et al.
Article dans une revue
hal-03607757
v1
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4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-b-lactamase inhibitors
Laurent Gavara
,
Alice Legru
,
Federica Verdirosa
,
Laurent Sevaille
,
Lionel Nauton
et al.
Article dans une revue
hal-03358457
v1
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QM/MM Study of Human Transketolase: Thiamine Diphosphate Activation Mechanism and Complete Catalytic Cycle
Lionel Nauton
,
Laurence Hecquet
,
Vincent Théry
Article dans une revue
hal-03286397
v1
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Pyruvate Aldolases Catalyze Cross-Aldol Reactions between Ketones: Highly Selective Access to Multi-Functionalized Tertiary Alcohols
Victor Laurent
,
Léa Gourbeyre
,
Alexandre Uzel
,
Virgil Hélaine
,
Lionel Nauton
et al.
Article dans une revue
hal-02907546
v1
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Enzymatic Synthesis of Aliphatic Acyloins through Thermostable Transketolase Catalyzed-Reaction
Hubert Casajus
,
Aurélie Lagarde
,
Martin Leremboure
,
Thomas De Dios Miguel
,
Lionel Nauton
et al.
Article dans une revue
hal-02995504
v1
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Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia
Alexia Visseq
,
Amélie Descheemaeker
,
Nicolas Pinto-Pardo
,
Lionel Nauton
,
Vincent Thery
et al.
Article dans une revue
hal-02444268
v1
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4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition
Laurent Gavara
,
Federica Verdirosa
,
Alice Legru
,
Paola Sandra Mercuri
,
Lionel Nauton
et al.
Article dans une revue
hal-02997710
v1
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Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest
Nahida Mokhtari Brikci-Nigassa
,
Lionel Nauton
,
Pascale Moreau
,
Olivier Mongin
,
Raphael E Duval
et al.
Article dans une revue
hal-02404054
v1
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Evolved Thermostable Transketolase for Stereoselective Two-Carbon Elongation of Non-Phosphorylated Aldoses to Naturally Rare Ketoses
Marion Lorillière
,
Romain Dumoulin
,
Mélanie L’enfant
,
Agnès Rambourdin
,
Vincent Thery
et al.
Article dans une revue
hal-02195534
v1
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Diastereoselective Synthesis of 2,6-Disubstituted-1,2,3,6-Tetrahydropyridines through a Palladium-Catalyzed Intramolecular Allylic Amination
Alexia Visseq
,
Thibaut Boibessot
,
Lionel Nauton
,
Vincent Thery
,
Fabrice Anizon
et al.
Article dans une revue
hal-02444228
v1
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Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies
Waël Zeinyeh
,
Yannick Esvan
,
Béatrice Josselin
,
Blandine Baratte
,
Stéphane Bach
et al.
Article dans une revue
hal-02164744
v1
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Achiral Hydroxypyruvaldehyde Phosphate as a Platform for Multi-Aldolases Cascade Synthesis of Diuloses and for a Quadruple Acetaldehyde Addition Catalyzed by 2-Deoxyribose-5-Phosphate Aldolases
Victor Laurent
,
Virgil Hélaine
,
Carine Vergne-Vaxelaire
,
Lionel Nauton
,
Mounir Traïkia
et al.
Article dans une revue
hal-02329545
v1
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NC α‐ gem ‐dimethylated peptoid side chains: A novel approach for structural control and peptide sequence mimetics
Radhe Shyam
,
Lionel Nauton
,
Gaetano Angelici
,
Olivier Roy
,
Claude Taillefumier
et al.
Article dans une revue
hal-02194898
v1
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Topologically Diverse Shapes Accessible by Modular Design of Arylopeptoid Macrocycles
Thomas Hjelmgaard
,
Lionel Nauton
,
Francesco de Riccardis
,
Laurent Jouffret
,
Sophie Faure
Article dans une revue
hal-01705225
v1
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Synthesis of Branched-Chain Sugars with a DHAP-Dependent Aldolase: Ketones are Electrophile Substrates of Rhamnulose-1- phosphate Aldolases
Victor Laurent
,
Ekaterina Darii
,
Angelina Aujon
,
Marine Debacker
,
Jean-Louis Petit
et al.
Article dans une revue
hal-02323732
v1
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A catalytic intramolecular nitrene insertion into a copper(I)–N-heterocyclic carbene bond yielding fused nitrogen heterocycles.
Kévin Fauché
,
Lionel Nauton
,
Laurent Jouffret
,
Federico Cisnetti
,
Arnaud Gautier
Article dans une revue
hal-01546151
v1
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1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases
Laurent Sevaille
,
Laurent Gavara
,
Carine Bebrone
,
Filomena De luca
,
Lionel Nauton
et al.
Article dans une revue
hal-02923462
v1
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Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co–crystal structure.
Yannick J. Esvan
,
Wael Zeinyeh
,
Thibaut Boibessot
,
Lionel Nauton
,
Vincent Théry
et al.
Article dans une revue
hal-01308803
v1
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Insights into the Thiamine Diphosphate Enzyme Activation Mechanism: Computational Model for Transketolase Using a Quantum Mechanical/Molecular Mechanical Method.
Lionel Nauton
,
Virgil Hélaine
,
Vincent Théry
,
Laurence Hecquet
Article dans une revue
hal-01323789
v1
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Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives.
Wael Zeinyeh
,
Yannick J. Esvan
,
Lionel Nauton
,
Nadège Loaëc
,
Laurent Meijer
et al.
Article dans une revue
hal-01367659
v1
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Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.
Yannick J. Esvan
,
Francis Giraud
,
Elisabeth Pereira
,
Virginie Suchaud
,
Lionel Nauton
et al.
Article dans une revue
hal-01367761
v1
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Water-Soluble Gold–N-Heterocyclic Carbene Complexes for the Catalytic Homogeneous Acid- and Silver-Free Hydration of Hydrophilic Alkynes.
Houssein Ibrahim
,
Pierre De frémont
,
Pierre Braunstein
,
Vincent Théry
,
Lionel Nauton
et al.
Article dans une revue
istex
hal-01264762
v1
|
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Engineering a Thermostable Transketolase for Unnatural Conversion of (2S)-Hydroxyaldehyde.
Juliane Abdoul-Zabar
,
Marion Lorillière
,
Dong Yi
,
Thangavelu Saravanan
,
Titu Devamani
et al.
Article dans une revue
istex
hal-01206477
v1
|
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Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition
Virginie Suchaud
,
Laurent Gavara
,
Francis Giraud
,
Lionel Nauton
,
Vincent Théry
et al.
Article dans une revue
hal-01077451
v1
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New N-1,N-10 bridged pyrrolo[2,3-a]carbazole-3-carbaldehyde: synthesis and biological activities.
Francis Giraud
,
Marion Bourhis
,
Lionel Nauton
,
Vincent Théry
,
Lars Herfindal
et al.
Article dans une revue
hal-01077457
v1
|
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New potent and selective inhibitor of Pim-1/3 protein kinases sensitizes human colon carcinoma cells to doxorubicin.
Pascale Moreau
,
Lyubov G. Dezhenkova
,
Fabrice Anizon
,
Lionel Nauton
,
Vincent Thery
et al.
Article dans une revue
istex
hal-01077420
v1
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Macrocyclic arylopeptoids - a novel type of cyclic N-alkylated aromatic oligoamides forming nanotubular assemblies.
Thomas Hjelmgaard
,
Olivier Roy
,
Lionel Nauton
,
Malika El-Ghozzi
,
Daniel Avignant
et al.
Article dans une revue
hal-00987596
v1
|
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Are Cu(I)-mesoionic NHC carbenes associated with nitrogen additives the best Cu-carbene catalysts for the azide-alkyne click reaction in solution? A case study.
Stephan Hohloch
,
Biprajit Sarkar
,
Lionel Nauton
,
Federico Cisnetti
,
Arnaud Gautier
Tetrahedron Letters, 2013, 54, pp.1808-1812
Article dans une revue
hal-00812528
v1
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Luminogenic "Clickable" Lanthanide Complexes for Protein Labeling.
Nicolas Candelon
,
Niculina D. Hădade
,
Mihaela Matache
,
Jean-Louis Canet
,
Federico Cisnetti
et al.
Chemical Communications, 2013, 49, pp.9206-9208
Article dans une revue
hal-00950489
v1
|
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Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.
Laurent Gavara
,
Virginie Suchaud
,
Lionel Nauton
,
Vincent Théry
,
Fabrice Anizon
et al.
Article dans une revue
istex
hal-01089114
v1
|
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Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors.
Virginie Suchaud
,
Laurent Gavara
,
Emmanuelle Saugues
,
Lionel Nauton
,
Vincent Théry
et al.
Article dans une revue
istex
hal-01089084
v1
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Synthesis, characterization, X-ray structure, DNA cleavage and cytotoxic activities of palladium(II) complexes of 4-phenyl-3-thiosemicarbazide and triphenylphosphine.
Fillipe Vieira Rocha
,
Carolina Valério Barra
,
Antonio Eduardo Mauro
,
Iracilda Z. Carlos
,
Lionel Nauton
et al.
European Journal of Inorganic Chemistry, 2013, pp.4499-4505
Article dans une revue
hal-00948885
v1
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Structure-Based Design of PDZ Ligands as Inhibitors of 5-HT2A Receptor/PSD-95 PDZ1 Domain Interaction Possessing Anti-hyperalgesic Activity
Alexandre Vogrig
,
Liam Dorr
,
Naoual Bouzidi
,
Benjamin Boucherle
,
Anne-Sophie Wattiez
et al.
Article dans une revue
hal-00948867
v1
|
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Clicked europium dipicolinate complexes for protein X-ray structure determination
Romain Talon
,
Lionel Nauton
,
Jean-Louis Canet
,
Richard Kahn
,
Eric Girard
et al.
Chemical Communications, 2012, 48, pp.11886-11888
Article dans une revue
hal-00787224
v1
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Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.
Francis Giraud
,
Rufine Akué-Gédu
,
Lionel Nauton
,
Nicolas Candelon
,
Eric Debiton
et al.
European Journal of Medicinal Chemistry, 2012, 56, pp.225-236
Article dans une revue
hal-00786353
v1
|
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FSAB: A new fructose-6-phosphate aldolase from Escherichia coli. Cloning, over-expression and comparative kinetic characterization with FSAA
Israel Sanchez-Moreno
,
Lionel Nauton
,
Vincent Théry
,
Agnès Pinet
,
Jean-Louis Petit
et al.
Journal of Molecular Catalysis B: Enzymatic, 2012, 84, pp.9-14
Article dans une revue
hal-00786230
v1
|
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Access to functionalised silver(I) and gold(I) N-heterocyclic carbenes by [2+3] dipolar cycloadditions.
Audrey Hospital
,
Clémentine Gibard
,
Christelle Gaulier
,
Lionel Nauton
,
Vincent Thery
et al.
Dalton Transactions, 2012, 41, pp.6803-6812
Article dans une revue
hal-00711788
v1
|
|
Synthesis, protein kinase inhibitory potencies and in vitro antiproliferative activities of meridianin derivatives.
Francis Giraud
,
Georges Alves
,
Eric Debiton
,
Lionel Nauton
,
Vincent Thery
et al.
Journal of Medicinal Chemistry, 2011, 54, pp.4474-4489
Article dans une revue
hal-00609607
v1
|
|
A platinum Chugaev carbene complex as a potent anticancer agent
Georges Alves
,
Laurent Morel
,
Malika El-Ghozzi
,
Daniel Avignant
,
Bertrand Legeret
et al.
Chemical Communications, 2011, 47, pp.7830-7832
Article dans une revue
hal-00609652
v1
|
|
Synthesis and molecular modelling study of new trimeric quinoline derivatives
Emmanuelle Saugues
,
Lionel Nauton
,
Vincent Thery
,
Fabrice Anizon
,
Pascale Moreau
Bioorganic Chemistry, 2011, 39, pp.143-150
Article dans une revue
hal-00625030
v1
|
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Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles
Rufine Akué-Gédu
,
Lionel Nauton
,
Vincent Thery
,
Jenny Bain
,
Philip Cohen
et al.
Bioorganic and Medicinal Chemistry, 2010, 18, pp.6865-6873
Article dans une revue
hal-00530591
v1
|
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Aromatic Nitrogen Donors for Efficient Copper(I)-NHC CuAAC under reductant-free conditions.
Marie-Laure Teyssot
,
Lionel Nauton
,
Jean-Louis Canet
,
Federico Cisnetti
,
Aurélien Chevry
et al.
Article dans une revue
istex
hal-00492922
v1
|
|
Click Chelators – The Behavior of Platinum and Palladium Complexes in the Presence of Guanosine and DNA
Aurélien Chevry
,
Marie-Laure Teyssot
,
Aurélie Maisonial
,
Pascale Lemoine
,
Bernard Viossat
et al.
Article dans une revue
istex
hal-00530546
v1
|
|
Structural insights into the design of inhbitors for the L1 metallo-ß-lactamase from Stenotrophomonas maltophilia
Lionel Nauton
,
Richard Kahn
,
G. Garau
,
Jean-François Hernandez
,
Otto Dideberg
Article dans une revue
istex
hal-00341669
v1
|
|
X-ray spectroscopy and X-ray diffraction at wavelengths near the K-absorption edge of phosphorus.
Valérie Biou
,
Peter Bösecke
,
Jean Marie Bois
,
Gérard Brandolin
,
Richard Kahn
et al.
Article dans une revue
hal-00376039
v1
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