Gervaise Loirand

44
Documents

Publications

Publications

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Platelets in Intracranial Aneurysm: The Missing Actors in the Drama?

Clémence Maupu , Garance Ennesser , Celine Baron-Menguy , Maxence Bodet , Gervaise Loirand et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2026, 46 (3), ⟨10.1161/atvbaha.125.323171⟩

Article dans une revue hal-05549193v1
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Identification of rare missense variants reducing cathepsin O secretion in families with intracranial aneurysm

Milène Fréneau , Raphael Blanchet , Maxence Bodet , Sandro Benichi , Mary-Adel Mrad et al.

Cardiovascular Research, 2026, 2026, pp.cvaf279

Article dans une revue hal-05477295v1
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A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer

Florian Dilasser , Lindsay Rose , Agnès Quemener , Yann Ferrandez , Dorian Hassoun et al.

Cell Reports Medicine, 2025, 6 (7), pp.102233. ⟨10.1016/j.xcrm.2025.102233⟩

Article dans une revue hal-05239632v1
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ARHGEF18 is a flow-responsive exchange factor controlling endothelial tight junctions and vascular leakage

Surya Prakash Rao Batta , Marc Rio , Corentin Lebot , Céline Baron-Menguy , Maxence Bodet et al.

Cell Reports, 2025, 44 (3), pp.115288. ⟨10.1016/j.celrep.2025.115288⟩

Article dans une revue hal-05241273v1

Impact de l'activation de Rac1 dans la dégranulation des éosinophiles au cours de l'asthme sévère

H Bergereau , D Hassoun , Q Marquant , M Rousselle , A Magnan et al.

Revue des Maladies Respiratoires, 2025, ⟨10.1016/j.rmr.2025.02.006⟩

Article dans une revue hal-05034532v1
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Allergic Sensitization Driving Immune Phenotyping and Disease Severity in a Mouse Model of Asthma

Eléonore Dijoux , Martin Klein , Barbara Misme-Aucouturier , Marie-Aude Chemina , Marion de Carvalho et al.

Allergy, Asthma & Immunology Research, 2023, 15 (2), pp.e9. ⟨10.4168/aair.2023.15.e9⟩

Article dans une revue hal-03953921v1
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Sildenafil-Induced Revascularization of Rat Hindlimb Involves Arteriogenesis through PI3K/AKT and eNOS Activation

Celine Baron-Menguy , Arnaud Bocquet , Alexis Richard , Anne-Laure Guihot , Bertrand Toutain et al.

International Journal of Molecular Sciences, 2022, 23, ⟨10.3390/ijms23105542⟩

Article dans une revue hal-03814145v1
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Bronchial smooth muscle cell in asthma: where does it fit?

Dorian Hassoun , Lindsay Rose , François-Xavier Blanc , Antoine O. Magnan , Gervaise Loirand et al.

BMJ open respiratory research, 2022, 9 (1), pp.e001351. ⟨10.1136/bmjresp-2022-001351⟩

Article dans une revue hal-03837374v1
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Location of intracranial aneurysms is the main factor associated with rupture in the ICAN population

Olivia Rousseau , Matilde Karakachoff , Alban Gaignard , Lise Bellanger , Philippe Bijlenga et al.

Journal of Neurology, Neurosurgery and Psychiatry, 2021, 92 (2), jnnp-2020-324371. ⟨10.1136/jnnp-2020-324371⟩

Article dans une revue hal-03033899v1
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Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling

Florian Dilasser , Lindsay Rose , Dorian Hassoun , Martin Klein , Morgane Rousselle et al. Article dans une revue hal-03142499v2
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Prediction of Unruptured Intracranial Aneurysm Evolution: The UCAN Project

Vincent L'Allinec , Stéphanie Chatel , Matilde Karakachoff , Emmanuelle Bourcereau , Zeineb Es-Salah-Lamoureux et al.

Neurosurgery, 2020, ⟨10.1093/neuros/nyaa093⟩

Article dans une revue hal-02889889v1
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Moringa oleifera Seeds Improve Aging-Related Endothelial Dysfunction in Wistar Rats

Joseph Iharinjaka Randriamboavonjy , Sandrine Heurtebise , Pierre Pacaud , Gervaise Loirand , Angela Tesse

Oxidative Medicine and Cellular Longevity, 2019, 2019, pp.2567198. ⟨10.1155/2019/2567198⟩

Article dans une revue hal-02152327v1
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Nouveaux acteurs dans la physiopathologie de l’asthme

Martin Klein , Eléonore Dijoux , Florian Dilasser , Dorian Hassoun , Antoine Moui et al.

La Presse Médicale, 2019, 48 (3), pp.255-261. ⟨10.1016/j.lpm.2019.01.004⟩

Article dans une revue hal-02101364v1

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome

Nadjet Belbachir , Vincent Portero , Zeina Al Sayed , Jean-Baptiste Gourraud , Florian Dilasser et al.

European Heart Journal, 2019, ⟨10.1093/eurheartj/ehz308⟩

Article dans une revue inserm-02158572v1
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Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm

Romain Bourcier , Solena Le Scouarnec , Stéphanie Bonnaud , Matilde Karakachoff , Emmanuelle Bourcereau et al.

American Journal of Human Genetics, 2018, 102 (1), pp.133 - 141. ⟨10.1016/j.ajhg.2017.12.006⟩

Article dans une revue hal-01808225v1
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In Vitro and In Vivo Approaches to Assess Rho Kinase Activity

Vincent Sauzeau , Gervaise Loirand

Methods in Molecular Biology, 2017, Hypertension Methods and Protocols, 1527, pp.213--218. ⟨10.1007/978-1-4939-6625-7_17⟩

Article dans une revue hal-01832946v1

Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1

Jonatan Barrera-Chimal , Gwennan André-Grégoire , Aurelie Nguyen Dinh Cat , Sebastian M. Lechner , Jérôme Cau et al.

Journal of the American Society of Nephrology, 2017, 28 (4), pp.1216-1226. ⟨10.1681/ASN.2016040477⟩

Article dans une revue hal-01832953v1
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Understanding the Pathophysiology of Intracranial Aneurysm: The ICAN Project

Romain Bourcier , Stéphanie Chatel , Emmanuelle Bourcereau , Solène Jouan , Hervé Le Marec et al.

Neurosurgery, 2017, 80 (4), pp.621-626. ⟨10.1093/neuros/nyw135⟩

Article dans une revue hal-01768333v1
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Targeting of Rac1 prevents bronchoconstriction and airway hyperresponsiveness

Gwennan André-Grégoire , Florian Dilasser , Julie Chesné , Faouzi Braza , Antoine Magnan et al.

Journal of Allergy and Clinical Immunology, 2017, Equipe III, ⟨10.1016/j.jaci.2017.09.049⟩

Article dans une revue hal-01828862v1
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Moringa oleifera Seeds Attenuate Vascular Oxidative and Nitrosative Stresses in Spontaneously Hypertensive Rats

Joseph Iharinjaka Randriamboavonjy , Marc Rio , Pierre Pacaud , Gervaise Loirand , Angela Tesse

Oxidative Medicine and Cellular Longevity, 2017, 2017, pp.4129459. ⟨10.1155/2017/4129459⟩

Article dans une revue hal-01832936v1
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Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis

Maria Luigia Carbone , Gilliane Chadeuf , Sandrine Heurtebise-Chrétien , Xavier Prieur , Thibault Quillard et al.

Journal of Clinical Investigation, 2017, Equipe III Equipe IV, 127 (12), pp.4516--4526. ⟨10.1172/JCI92702⟩

Article dans une revue hal-01832942v1

Cardiac protective effects of Moringa oleifera seeds in spontaneous hypertensive rats

Joseph Randriamboavonjy , Gervaise Loirand , Nathalie Vaillant , Benjamin Lauzier , Séverine Derbré et al.

American Journal of Hypertension, 2016, 29 (7), pp.873-881. ⟨10.1093/ajh/hpw001⟩

Article dans une revue hal-01389199v1
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Angiotensin II Activates the RhoA Exchange Factor Arhgef1 in Humans

Maria Luigia Carbone , Jérémy Brégeon , Nabila Devos , Gilliane Chadeuf , Anne Blanchard et al.

Hypertension, 2015, Equipe 2, 65 (6), pp.1273--1278. ⟨10.1161/HYPERTENSIONAHA.114.05065⟩

Article dans une revue hal-01830595v1

Rho Kinases in Health and Disease: From Basic Science to Translational Research

Gervaise Loirand

Pharmacological Reviews, 2015, 67 (4), pp.1074--1095. ⟨10.1124/pr.115.010595⟩

Article dans une revue hal-01830591v1

SUN2 accumulation contributes to vascular smooth muscle cell alterations induced by matrix rigidity

Néjma Bélaadi , Gilliane Chadeuf , Luan Nguyen , Marc Rio , G. Louarn et al.

FASEB Journal, 2015, 29

Article dans une revue hal-01726012v1

Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model

Julie Chesné , Faouzi Braza , Gilliane Chadeuf , Guillaume Mahay , Marie-Aude Cheminant et al.

Journal of Allergy and Clinical Immunology, 2015, 135 (6), pp.1643-1643.e3. ⟨10.1016/j.jaci.2014.12.1872⟩

Article dans une revue hal-01830585v1

Increased β2-adrenergic vasorelaxation at the early phase of endotoxemic shock in rats

David Roul , Bertrand Rozec , Gwenann André , Nolwenn Merlet , T. Tran Quang et al.

Vascular Pharmacology, 2015, Equipe 1 Equipe 2, 72, pp.181--189. ⟨10.1016/j.vph.2015.04.007⟩

Article dans une revue istex hal-01830593v1

PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension

Jean-Mathieu Berger , Nathalie Vaillant , Cedric Le May , Carolina Calderon , Jeremy Brégeon et al.

Atherosclerosis, 2015, Equipe 2 Equipe 5, 239 (1), pp.252--259. ⟨10.1016/j.atherosclerosis.2015.01.012⟩

Article dans une revue hal-01830594v1
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Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response

Natalia F. Smirnova , Stephanie Gayral , Christophe Pedros , Gervaise Loirand , Nathalie Vaillant et al.

Journal of Experimental Medicine, 2014, 211 (9), pp.1779-1792. ⟨10.1084/jem.20131276⟩

Article dans une revue hal-02519407v1

Smooth Muscle Specific Rac1 Deficiency Induces Hypertension by Preventing p116 RIP 3 ‐Dependent RhoA Inhibition

Gwennan André , Juan Sandoval , Kevin Retailleau , Laurent Loufrani , Gilles Toumaniantz et al.

Journal of the American Heart Association, 2014, 3 (3), ⟨10.1161/JAHA.114.000852⟩

Article dans une revue hal-02347180v1

Advanced glycation inhibition and protection against endothelial dysfunction induced by coumarins and procyanidins from Mammea neurophylla.

Bach Tai Dang , Charlotte Gény , Patricia Blanchard , Caroline Rouger , Pierre Tonnerre et al.

Fitoterapia, 2014, 96, pp.65-75. ⟨10.1016/j.fitote.2014.04.005⟩

Article dans une revue istex hal-01059141v1

n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet

Fatima Kasbi Chadli , Agnès André , Xavier Prieur , Gervaise Loirand , Anne Meynier et al.

British Journal of Nutrition, 2012, 107 (9), pp.1305 - 1315. ⟨10.1017/S0007114511004387⟩

Article dans une revue hal-02644896v1

WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.

Sonia Bergaya , Sébastien Faure , Véronique Baudrie , Marc Rio , Brigitte Escoubet et al.

Hypertension, 2011, 58 (3), pp.439-45. ⟨10.1161/HYPERTENSIONAHA.111.172429⟩

Article dans une revue hal-00945534v1

Regulation of Rho signaling pathways in interleukin-2-stimulated human T-lymphocytes.

Rym Mzali , Laetitia Seguin , Caroline Liot , Anick Auger , Pierre Pacaud et al.

FASEB Journal, 2005, 19 (13), pp.1911-3. ⟨10.1096/fj.05-4030fje⟩

Article dans une revue hal-00192794v1

Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells.

Malvyne Rolli-Derkinderen , Vincent Sauzeau , Laurent Boyer , Emmanuel Lemichez , Céline Baron et al.

Circulation Research, 2005, 96, pp.1152-60. ⟨10.1161/01.RES.0000170084.88780.ea⟩

Article dans une revue inserm-00000098v1

Structure–Activity Relationships of Human Urotensin II and Related Analogues on Rat Aortic Ring Contraction

Patricia Labarrère , David Chatenet , Jérôme Leprince , Céline Marionneau , Gervaise Loirand et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2003, 18 (2), pp.77-88. ⟨10.1080/1475636031000093507⟩

Article dans une revue hal-01962785v1

Dependence of P2-nucleotide receptor agonist-mediated endothelium-independent relaxation on ectonucleotidase activity and A 2A -receptors in rat portal vein

Christelle Guibert , Gervaise Loirand , Paul Vigne , Jean-Pierre Savineau , Pierre Pacaud

British Journal of Pharmacology, 1998, 123 (8), pp.1732-1740. ⟨10.1038/sj.bjp.0701773⟩

Article dans une revue hal-02439074v1
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Autoanti-phosphatidylinositide antibodies specifically inhibit noradrenaline effects on Ca2+ and Cl- channels in rat portal vein myocytes.

Gervaise Loirand , Sylvie Faiderbe , Anne Baron , Michel Geffard , Jean Mironneau

Journal of Biological Chemistry, 1992, 267 (7), pp.4312-4316

Article dans une revue hal-02277572v1

Ca2+ channel activation and membrane depolarization mediated by Cl− channels in response to noradrenaline in vascular myocytes

Pierre Pacaud , Gervaise Loirand , Anne Baron , Chantal Mironneau , Jean Mironneau

British Journal of Pharmacology, 1991, 104 (4), pp.1000-1006. ⟨10.1111/j.1476-5381.1991.tb12540.x⟩

Article dans une revue hal-02277610v1