MC

MAELLE CARRAZ

CRCN IRD at MCD and PHARMADEV
21
Documents

Présentation

I’m a chemical biologist and a natural product (NP) expert working on plant-biodiversity and its use in many fields of biology. I am performing both analytical chemistry for new NPs identification and cell biology to develop original assays for NPs bioactivity/ phenotypic screening. I am also developing projects dealing with epigenetics and cellular senescence. I set up a team (Jeune Equipe Associée à l’IRD, 2020-22) in IRSS Burkina Faso (Africa) to perform cellular assays on plants used in traditional medicine. I am coordinating several projects at the chemistry-biology interface.


Compétences

analytical chemistry, cell biology, pharmacochemistry, chemical biology

Publications

Publications

Comparative analysis of the regulations for the marketing and quality control of herbal products used for health purposes in France, Peru and West Africa

Inés Yolanda Castro-Dionicio , Charlotte Dumondin , Latifou Lagnika , Nicolas Fabre , Rokia Sanogo et al.
Tropical Medicine & International Health, 2025, ⟨10.1111/tmi.70061⟩
Article dans une revue hal-05360707 v1
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Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Rainatou Boly , Abdourahim Kindo , Tata Kadiatou Traore , Wendkouni Leila M. Esther Belem-Kabre , Lassina Barro et al.
African Journal of Pharmacy and Pharmacology, 2023, 17 (9), pp.182-190. ⟨10.5897/ajpp2023.5369⟩
Article dans une revue hal-04738389 v1

Liver cancer antiproliferative activity of a new nor-cucurbitacin from Mareya micrantha Müll. Arg.

Gnaoré Yoh Toussaint-Douhoré , Yaya Soro , Noufou Ouédraogo , Carlos Vaca-Garcia , Barthélemy Koffi-Attioua et al.
Fitoterapia, 2023, 166, pp.105471. ⟨10.1016/j.fitote.2023.105471⟩
Article dans une revue hal-04056446 v1
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Potent antiplasmodial derivatives of dextromethorphan reveal the ent-morphinan pharmacophore of tazopsine-type alkaloids

Antoinette Keita , Jean-François Franetich , Maëlle Carraz , Loïse Valentin , Mallaury Bordessoules et al.
Pharmaceutics, 2022, 14 (2), pp.372. ⟨10.3390/pharmaceutics14020372⟩
Article dans une revue hal-03594207 v1
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Triterpenoid saponins from Calliandra calothyrsus Meisn. and their antiproliferative activity against two digestive carcinoma human cell lines

Lin Marcellin Messi , Olivier Placide Noté , Joséphine Ngo Mbing , Pierre Lavedan , Marc Vedrenne et al.
Fitoterapia, 2020, 146, pp.104669 -. ⟨10.1016/j.fitote.2020.104669⟩
Article dans une revue hal-03490857 v1
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Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

André Tibiri , Sébastien Boria , Tata Kadiatou Traoré , Noufou Ouédraogo , Aude Nikièma et al.
Frontiers in Pharmacology, 2020, 11, pp.563751. ⟨10.3389/fphar.2020.563751⟩
Article dans une revue hal-03549227 v1

XANTHONES FROM Hypericum laricifolium Juss., AND THEIR ANTIPROLIFERATIVE ACTIVITY AGAINST HEP3B CELLS.

Moisela Marlon Miguel Morales , Brel Orianne , Bourdy Geneviève , Cruza Mercedes Gonzales de La , Dionicio Inés Yolanda Castro et al.
Rev Soc Quím Perú. , 2018
Article dans une revue hal-04738484 v1
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Phenolic Compounds Isolated from Caesalpinia coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines

Jessica Nayelli Sánchez-Carranza , Laura Alvarez , Silvia Marquina-Bahena , Enrique Salas-Vidal , Verónica Cuevas et al.
Molecules, 2017, 22 (4), pp.666. ⟨10.3390/molecules22040666⟩
Article dans une revue hal-03152330 v1
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MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence

Raphael Culerrier , Maëlle Carraz , Carl Mann , Malek Djabali
Molecular Biology of the Cell, 2016, 27 (17), pp.2726 - 2734. ⟨10.1091/mbc.E15-11-0772⟩
Article dans une revue hal-01412354 v1

Synthesis, Structures, and Biological Studies of Heterobimetallic Au(I)–Ru(II) Complexes Involving N-Heterocyclic Carbene-Based Multidentate Ligands

Luca Boselli , Maëlle Carraz , Serge Mazères , Lucie Paloque , Germán González et al.
Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩
Article dans une revue hal-04738497 v1

Antiproliferative activity and phenotypic modification induced by selected Peruvian medicinal plants on human hepatocellular carcinoma Hep3B cells

Maëlle Carraz , Cédric Lavergne , Valérie Jullian , Michel Wright , Jean Edouard Gairin et al.
Journal of Ethnopharmacology, 2015, 166, pp.185-199. ⟨10.1016/j.jep.2015.02.028⟩
Article dans une revue istex hal-04738492 v1

Synthesis, structures, and biological studies of heterobimetallic Au(I)-Ru(II) complexes involving N-heterocyclic carbene-based multidentate ligands

Luca Boselli , Maëlle Carraz , S. Mazeres , Lucie Paloque , German Gonzalez-Aspajo et al.
Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩
Article dans une revue hal-01925137 v1

Synthesis and cytotoxic activity of a novel dihydroisoquinoline-derived hydroxamic acid

Hassen Ben Salah , Maëlle Carraz , Majed Kammoun
Journal of Advances in Chemistry, 2014, 10 (4), pp.2648-2653. ⟨10.24297/jac.v10i4.5503⟩
Article dans une revue hal-04741099 v1

Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands

Luca Boselli , Isabelle Ader , Maëlle Carraz , Catherine Hemmert , Olivier Cuvillier et al.
European Journal of Medicinal Chemistry, 2014, 85, pp.87-94. ⟨10.1016/j.ejmech.2014.07.086⟩
Article dans une revue istex hal-02007936 v1

In vitro growth inhibitory effects of 13,28-epoxyoleanane triterpene saponins in cancer cells

Mohamed Haddad , Anne-Cécile Lelamer , Laetitia Moreno Y Banuls , Pedro Vasquez , Maëlle Carraz et al.
Phytochemistry Letters, 2013, 6 (1), pp.128-134. ⟨10.1016/j.phytol.2012.11.011⟩
Article dans une revue istex hal-04741121 v1
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A plant-derived morphinan as a novel lead compound active against malaria liver stages.

Maëlle Carraz , Akino Jossang , Jean-François Franetich , Anthony Siau , Liliane Ciceron et al.
PLoS Medicine, 2006, 3 (12), pp.e513. ⟨10.1371/journal.pmed.0030513⟩
Article dans une revue hal-00148373 v1

Design and synthesis of novel imidazo[1,2- a ]quinoxalines as PDE4 inhibitors

Carine Deleuze-Masquéfa , Grégori Gerebtzoff , Guy Subra , Jean-Roch Fabreguettes , Annabel Ovens et al.
Bioorganic and Medicinal Chemistry, 2004, 12 (5), pp.1129-1139. ⟨10.1016/j.bmc.2003.11.034⟩
Article dans une revue istex hal-04741189 v1