MAELLE CARRAZ

CRCN IRD at MCD and PHARMADEV
19
Documents

Présentation

I’m a chemical biologist and a natural product (NP) expert working on plant-biodiversity and its use in many fields of biology. I am performing both analytical chemistry for new NPs identification and cell biology to develop original assays for NPs bioactivity/ phenotypic screening. I am also developing projects dealing with epigenetics and cellular senescence. I set up a team (Jeune Equipe Associée à l’IRD, 2020-22) in IRSS Burkina Faso (Africa) to perform cellular assays on plants used in traditional medicine. I am coordinating several projects at the chemistry-biology interface.


Compétences

analytical chemistry, cell biology, pharmacochemistry, chemical biology

Publications

Publications

Liver cancer antiproliferative activity of a new nor-cucurbitacin from Mareya micrantha Müll. Arg.

Gnaoré Yoh Toussaint-Douhoré , Yaya Soro , Noufou Ouédraogo , Carlos Vaca-Garcia , Barthélemy Koffi-Attioua et al.
Fitoterapia, 2023, 166, pp.105471. ⟨10.1016/j.fitote.2023.105471⟩
Article dans une revue hal-04056446 v1

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Rainatou Boly , Abdourahim Kindo , Tata Kadiatou Traore , Wendkouni Leila M. Esther Belem-Kabre , Lassina Barro et al.
African Journal of Pharmacy and Pharmacology, 2023, 17 (9), pp.182-190. ⟨10.5897/ajpp2023.5369⟩
Article dans une revue hal-04738389 v1
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Potent antiplasmodial derivatives of dextromethorphan reveal the ent-morphinan pharmacophore of tazopsine-type alkaloids

Antoinette Keita , Jean-François Franetich , Maëlle Carraz , Loïse Valentin , Mallaury Bordessoules et al.
Pharmaceutics, 2022, 14 (2), pp.372. ⟨10.3390/pharmaceutics14020372⟩
Article dans une revue hal-03594207 v1
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Triterpenoid saponins from Calliandra calothyrsus Meisn. and their antiproliferative activity against two digestive carcinoma human cell lines

Lin Marcellin Messi , Olivier Placide Noté , Joséphine Ngo Mbing , Pierre Lavedan , Marc Vedrenne et al.
Fitoterapia, 2020, 146, pp.104669 -. ⟨10.1016/j.fitote.2020.104669⟩
Article dans une revue hal-03490857 v1
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Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

André Tibiri , Sébastien Boria , Tata Kadiatou Traoré , Noufou Ouédraogo , Aude Nikièma et al.
Frontiers in Pharmacology, 2020, 11, pp.563751. ⟨10.3389/fphar.2020.563751⟩
Article dans une revue hal-03549227 v1

XANTHONES FROM Hypericum laricifolium Juss., AND THEIR ANTIPROLIFERATIVE ACTIVITY AGAINST HEP3B CELLS.

Moisela Marlon Miguel Morales , Brel Orianne , Bourdy Geneviève , Cruza Mercedes Gonzales de La , Dionicio Inés Yolanda Castro et al.
Rev Soc Quím Perú. , 2018
Article dans une revue hal-04738484 v1
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Phenolic Compounds Isolated from Caesalpinia coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines

Jessica Nayelli Sánchez-Carranza , Laura Alvarez , Silvia Marquina-Bahena , Enrique Salas-Vidal , Verónica Cuevas et al.
Molecules, 2017, 22 (4), pp.666. ⟨10.3390/molecules22040666⟩
Article dans une revue hal-03152330 v1
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MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence

Raphael Culerrier , Maëlle Carraz , Carl Mann , Malek Djabali
Molecular Biology of the Cell, 2016, 27 (17), pp.2726 - 2734. ⟨10.1091/mbc.E15-11-0772⟩
Article dans une revue hal-01412354 v1

Synthesis, Structures, and Biological Studies of Heterobimetallic Au(I)–Ru(II) Complexes Involving N-Heterocyclic Carbene-Based Multidentate Ligands

Luca Boselli , Maëlle Carraz , Serge Mazères , Lucie Paloque , Germán González et al.
Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩
Article dans une revue hal-04738497 v1

Antiproliferative activity and phenotypic modification induced by selected Peruvian medicinal plants on human hepatocellular carcinoma Hep3B cells

Maëlle Carraz , Cédric Lavergne , Valérie Jullian , Michel Wright , Jean Edouard Gairin et al.
Journal of Ethnopharmacology, 2015, 166, pp.185-199. ⟨10.1016/j.jep.2015.02.028⟩
Article dans une revue hal-04738492 v1

Synthesis, structures, and biological studies of heterobimetallic Au(I)-Ru(II) complexes involving N-heterocyclic carbene-based multidentate ligands

Luca Boselli , Maëlle Carraz , S. Mazeres , Lucie Paloque , German Gonzalez-Aspajo et al.
Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩
Article dans une revue hal-01925137 v1

Synthesis and cytotoxic activity of a novel dihydroisoquinoline-derived hydroxamic acid

Hassen Ben Salah , Maëlle Carraz , Majed Kammoun
Journal of Advances in Chemistry, 2014, 10 (4), pp.2648-2653. ⟨10.24297/jac.v10i4.5503⟩
Article dans une revue hal-04741099 v1

Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands

Luca Boselli , Isabelle Ader , Maëlle Carraz , Catherine Hemmert , Olivier Cuvillier et al.
European Journal of Medicinal Chemistry, 2014, 85, pp.87-94. ⟨10.1016/j.ejmech.2014.07.086⟩
Article dans une revue hal-02007936 v1

In vitro growth inhibitory effects of 13,28-epoxyoleanane triterpene saponins in cancer cells

Mohamed Haddad , Anne-Cécile Lelamer , Laetitia Moreno Y Banuls , Pedro Vasquez , Maëlle Carraz et al.
Phytochemistry Letters, 2013, 6 (1), pp.128-134. ⟨10.1016/j.phytol.2012.11.011⟩
Article dans une revue istex hal-04741121 v1
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A plant-derived morphinan as a novel lead compound active against malaria liver stages.

Maëlle Carraz , Akino Jossang , Jean-François Franetich , Anthony Siau , Liliane Ciceron et al.
PLoS Medicine, 2006, 3 (12), pp.e513. ⟨10.1371/journal.pmed.0030513⟩
Article dans une revue hal-00148373 v1

Design and synthesis of novel imidazo[1,2- a ]quinoxalines as PDE4 inhibitors

Carine Deleuze-Masquéfa , Grégori Gerebtzoff , Guy Subra , Jean-Roch Fabreguettes , Annabel Ovens et al.
Bioorganic and Medicinal Chemistry, 2004, 12 (5), pp.1129-1139. ⟨10.1016/j.bmc.2003.11.034⟩
Article dans une revue istex hal-04741189 v1