MC

MAELLE CARRAZ

CRCN IRD at MCD and PHARMADEV
23
Documents

Présentation

I’m a chemical biologist and a natural product (NP) expert working on plant-biodiversity and its use in many fields of biology. I am performing both analytical chemistry for new NPs identification and cell biology to develop original assays for NPs bioactivity/ phenotypic screening. I am also developing projects dealing with epigenetics and cellular senescence. I set up a team (Jeune Equipe Associée à l’IRD, 2020-22) in IRSS Burkina Faso (Africa) to perform cellular assays on plants used in traditional medicine. I am coordinating several projects at the chemistry-biology interface.


Compétences

analytical chemistry, cell biology, pharmacochemistry, chemical biology

Publications

Publications

2D Multimodal Image Collection for Fluorescence Prediction from Transmitted Light Microscopy

Dorian Kauffmann , Guillaume Gay , Julio Mateos-Langerak , Oriane Pourcelot , Virginie Georget et al.

Scientific Data , 2026, Online ahead of print. ⟨10.1038/s41597-026-07004-w⟩

Article dans une revue hal-05579341v1

Comparative analysis of the regulations for the marketing and quality control of herbal products used for health purposes in France, Peru and West Africa

Inés Yolanda Castro-Dionicio , Charlotte Dumondin , Latifou Lagnika , Nicolas Fabre , Rokia Sanogo et al.

Tropical Medicine and International Health, 2025, ⟨10.1111/tmi.70061⟩

Article dans une revue hal-05360707v1

Corrigendum to “Triterpenoid saponins from Calliandra calothyrsus Meisn. and their antiproliferative activity against two digestive carcinoma human cell lines” [Fitoterapia volume 146 (2020) p1-9/article 104669]

Lin Marcellin Messi , Olivier Placide Noté , Joséphine Ngo Mbing , Pierre Lavedan , Marc Vedrenne et al.

Fitoterapia, 2024, 175, pp.105934. ⟨10.1016/j.fitote.2024.105934⟩

Article dans une revue hal-04726040v1
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Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Rainatou Boly , Abdourahim Kindo , Tata Kadiatou Traore , Wendkouni Leila M. Esther Belem-Kabre , Lassina Barro et al.

African Journal of Pharmacy and Pharmacology, 2023, 17 (9), pp.182-190. ⟨10.5897/ajpp2023.5369⟩

Article dans une revue hal-04738389v1

Liver cancer antiproliferative activity of a new nor-cucurbitacin from Mareya micrantha Müll. Arg.

Gnaoré Yoh Toussaint-Douhoré , Yaya Soro , Noufou Ouédraogo , Carlos Vaca-Garcia , Barthélemy Koffi-Attioua et al.

Fitoterapia, 2023, 166, pp.105471. ⟨10.1016/j.fitote.2023.105471⟩

Article dans une revue hal-04056446v1
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Potent antiplasmodial derivatives of dextromethorphan reveal the ent-morphinan pharmacophore of tazopsine-type alkaloids

Antoinette Keita , Jean-François Franetich , Maëlle Carraz , Loïse Valentin , Mallaury Bordessoules et al.

Pharmaceutics, 2022, 14 (2), pp.372. ⟨10.3390/pharmaceutics14020372⟩

Article dans une revue hal-03594207v1
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Triterpenoid saponins from Calliandra calothyrsus Meisn. and their antiproliferative activity against two digestive carcinoma human cell lines

Lin Marcellin Messi , Olivier Placide Noté , Joséphine Ngo Mbing , Pierre Lavedan , Marc Vedrenne et al.

Fitoterapia, 2020, 146, pp.104669 -. ⟨10.1016/j.fitote.2020.104669⟩

Article dans une revue hal-03490857v1
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Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

André Tibiri , Sébastien Boria , Tata Kadiatou Traoré , Noufou Ouédraogo , Aude Nikièma et al.

Frontiers in Pharmacology, 2020, 11, pp.563751. ⟨10.3389/fphar.2020.563751⟩

Article dans une revue hal-03549227v1

XANTHONES FROM Hypericum laricifolium Juss., AND THEIR ANTIPROLIFERATIVE ACTIVITY AGAINST HEP3B CELLS.

Moisela Marlon Miguel Morales , Brel Orianne , Bourdy Geneviève , Cruza Mercedes Gonzales de La , Dionicio Inés Yolanda Castro et al.

Revista de la Sociedad Química del Perú, 2018

Article dans une revue hal-04738484v1
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Phenolic Compounds Isolated from Caesalpinia coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines

Jessica Nayelli Sánchez-Carranza , Laura Alvarez , Silvia Marquina-Bahena , Enrique Salas-Vidal , Verónica Cuevas et al.

Molecules, 2017, 22 (4), pp.666. ⟨10.3390/molecules22040666⟩

Article dans une revue hal-03152330v1
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MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence

Raphael Culerrier , Maëlle Carraz , Carl Mann , Malek Djabali

Molecular Biology of the Cell, 2016, 27 (17), pp.2726 - 2734. ⟨10.1091/mbc.E15-11-0772⟩

Article dans une revue hal-01412354v1

Synthesis, Structures, and Biological Studies of Heterobimetallic Au(I)–Ru(II) Complexes Involving N-Heterocyclic Carbene-Based Multidentate Ligands

Luca Boselli , Maëlle Carraz , Serge Mazères , Lucie Paloque , Germán González et al.

Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩

Article dans une revue hal-04738497v1

Antiproliferative activity and phenotypic modification induced by selected Peruvian medicinal plants on human hepatocellular carcinoma Hep3B cells

Maëlle Carraz , Cédric Lavergne , Valérie Jullian , Michel Wright , Jean Edouard Gairin et al.

Journal of Ethnopharmacology, 2015, 166, pp.185-199. ⟨10.1016/j.jep.2015.02.028⟩

Article dans une revue istex hal-04738492v1

Synthesis, structures, and biological studies of heterobimetallic Au(I)-Ru(II) complexes involving N-heterocyclic carbene-based multidentate ligands

Luca Boselli , Maëlle Carraz , S. Mazeres , Lucie Paloque , German Gonzalez-Aspajo et al.

Organometallics, 2015, 34 (6), pp.1046-1055. ⟨10.1021/om501158m⟩

Article dans une revue hal-01925137v1

Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands

Luca Boselli , Isabelle Ader , Maëlle Carraz , Catherine Hemmert , Olivier Cuvillier et al.

European Journal of Medicinal Chemistry, 2014, 85, pp.87-94. ⟨10.1016/j.ejmech.2014.07.086⟩

Article dans une revue istex hal-02007936v1

Synthesis and cytotoxic activity of a novel dihydroisoquinoline-derived hydroxamic acid

Hassen Ben Salah , Maëlle Carraz , Majed Kammoun

Journal of Advances in Chemistry, 2014, 10 (4), pp.2648-2653. ⟨10.24297/jac.v10i4.5503⟩

Article dans une revue hal-04741099v1

In vitro growth inhibitory effects of 13,28-epoxyoleanane triterpene saponins in cancer cells

Mohamed Haddad , Anne-Cécile Lelamer , Laetitia Moreno Y Banuls , Pedro Vasquez , Maëlle Carraz et al.

Phytochemistry Letters, 2013, 6 (1), pp.128-134. ⟨10.1016/j.phytol.2012.11.011⟩

Article dans une revue istex hal-04741121v1
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A plant-derived morphinan as a novel lead compound active against malaria liver stages.

Maëlle Carraz , Akino Jossang , Jean-François Franetich , Anthony Siau , Liliane Ciceron et al.

PLoS Medicine, 2006, 3 (12), pp.e513. ⟨10.1371/journal.pmed.0030513⟩

Article dans une revue hal-00148373v1

Design and synthesis of novel imidazo[1,2- a ]quinoxalines as PDE4 inhibitors

Carine Deleuze-Masquéfa , Grégori Gerebtzoff , Guy Subra , Jean-Roch Fabreguettes , Annabel Ovens et al.

Bioorganic and Medicinal Chemistry, 2004, 12 (5), pp.1129-1139. ⟨10.1016/j.bmc.2003.11.034⟩

Article dans une revue istex hal-04741189v1