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CV Mai


Mai NGUYEN-CHI, Ph.D , CRCN CNRS                                                 


Born 1981, French nationality – 2 Children


Phone +33 6 40322823 – Email:


French (Mother tongue), English and Italian (Good knowledge)




Laboratory of Pathogen Host Interactions/UMR5235, Université de Montpellier, France




Research Experience




2016-:             CR position at LPHI (DIMNP), CNRS/UMR5235, Montpellier, France,


Team of Dr G. Lutfalla


2013-2015 :    Post-doctorat  at Institute of Regenerative Medicine and Biotherapies, INSERM/U1183, Montpellier, France, Team of  Pr. C. Jorgensen


2011-2013 :    Post-doctorat  at DIMNP, CNRS/UMR5235, Montpellier, France,


Team of Dr G. Lutfalla


2009-2010 :     Post-doctorat  at the Australian Regenerative Medicine Institute, Monash University, Melbourne, Australia, Team of Pr. P. Currie


2004-2008 :     PhD student at the Centre de Biologie du Développement, CNRS/UMR5547, Toulouse, France, Team of Dr D. Morello and in the University of Firenze, Italy, Team of Pr S. Capaccioli








2004-2008 :     PhD studies in Molecular, Cellular and Developmental Biology, University of Toulouse


2003-2004 :     Master of Science, Paul Sabatier University


2001-2003 :     Undergraduate Degree, Paul Sabatier University


2019-2020:     Presently applying for the Habilitation à Diriger des Recherches (HDR), accepted by the University of Montpellier. HDR defense during the winter 2020.




Field of Interest




Onset of Immunity during injuries and bacterial infections in the zebrafish model


Innate immune cell activation, and polarization


Wound healing




Scientific Activity




12 publications in peer-reviewed journals(including 8 first author, 1 last author, 2 corresponding author),


1 preprint, currently two publications in preparation


4 grants (including 3 as PI): « ANR JCJC 2019 » from Agence Nationale pour la Recherche                           « Soutien à la recherche 2019 » from the  University of Montpellier.                                     « MuseExplore » (2018) from the  University of Montpellier                                                               Presently preparing an MSCA-ETN application as coordinator.


Supervision: 2 Marie Curie PhDs, 4 Master students


Organizer of the Zebrafish Meeting in Montpellier (every 2 weeks 2013-2015)


Teaching Cell biology (University of Toulouse, 2006), Immunology (University of Montpellier, 2017-2019)


Reviewerfor Fish and Shellfish Immunology and for Zebrafish




Invitations and international conferences




June 2019: Leiden, Netherland, Invited speaker by Annemarie Meijer, Leiden University


June 2019: Wageningen, Netherland, Opponent in a PhD defense at Wageningen University and Research


Nov. 2019: Oslo, Sweden, Invited speaker byGareth Griffiths, Faculty of Mathematics and Natural Sciences


Journal articles17 documents

  • Christina Begon-Pescia, Stéphanie Boireau, Myriam Boyer-Clavel, Georges Lutfalla, Mai Nguyen-Chi. Preparing sequencing grade RNAs from a small number of FACS-sorted larvae macrophages isolated from enzyme free dissociated zebrafish larvae. MethodsX, 2022, 9, ⟨10.1016/j.mex.2022.101651⟩. ⟨hal-03834650⟩
  • Guy Charmantier, Mai Nguyen-Chi, Georges Lutfalla. Ontogenetic Changes in Blood Osmolality During the Postembryonic Development of Zebrafish (Danio rerio). Zebrafish, 2022, 19 (1), pp.1 - 6. ⟨10.1089/zeb.2021.0075⟩. ⟨hal-03841275⟩
  • Tamara Sipka, Seol Ah Park, Resul Ozbilgic, Laurence Balas, Thierry Durand, et al.. Macrophages undergo a behavioural switch during wound healing in zebrafish. Free Radical Biology and Medicine, 2022, 192, pp.200-212. ⟨10.1016/j.freeradbiomed.2022.09.021⟩. ⟨hal-03794564⟩
  • Tamara Sipka, Romain Peroceschi, Rahma Hassan-Abdi, Martin Gross, Felix Ellett, et al.. Damage-Induced Calcium Signaling and Reactive Oxygen Species Mediate Macrophage Activation in Zebrafish. Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.636585⟩. ⟨hal-03334425⟩
  • Sem H Jacobs, Eva Dóró, Ffion R Hammond, Mai Nguyen-Chi, Georges Lutfalla, et al.. Occurrence of foamy macrophages during the innate response of zebrafish to trypanosome infections. eLife, 2021, 10, ⟨10.7554/elife.64520⟩. ⟨hal-03374717⟩
  • Béryl Laplace-Builhé, Audrey Barthelaix, Said Assou, Candice Bohaud, Marine Pratlong, et al.. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nature Communications, 2021, 12 (1), pp.6336. ⟨10.1038/s41467-021-26422-5⟩. ⟨hal-03646943⟩
  • Seol Ah Park, Tamara Sipka, Zuzana Kriva, Martin Ambroz, Michal Kollar, et al.. Macrophage image segmentation by Thresholding and subjective surface Method. Tatra Mountains Mathematical Publications, 2020, ⟨10.2478/tmmp-2020-0007⟩. ⟨hal-02390453⟩
  • Mai Nguyen-Chi, Patricia Luz-Crawford, Laurence Balas, Tamara Sipka, Rafael Contreras-López, et al.. Pro‐resolving mediator protectin D1 promotes epimorphic regeneration by controlling immune cell function in vertebrates. British Journal of Pharmacology, 2020, 177 (17), pp.4055-4073. ⟨10.1111/bph.15156⟩. ⟨hal-02993375⟩
  • Quang Tien Phan, Tamara Sipka, Catherine Gonzalez, Jean-Pierre Levraud, Georges Lutfalla, et al.. Neutrophils use superoxide to control bacterial infection at a distance. PLoS Pathogens, 2018, 14 (7), pp.e1007157. ⟨10.1371/journal.ppat.1007157⟩. ⟨hal-02086655⟩
  • Mai Nguyen-Chi, Béryl Laplace-Builhé, Jana Travnickova, Patricia Luz-Crawford, Gautier Tejedor, et al.. TNF signaling and macrophages govern fin regeneration in zebrafish larvae. Cell Death and Disease, 2017, 8, pp.e2979. ⟨10.1038/cddis.2017.374⟩. ⟨hal-02086729⟩
  • Audrey Bernut, Mai Nguyen-Chi, Iman Halloum, Jean-Louis Herrmann, Georges Lutfalla, et al.. Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking. PLoS Pathogens, 2016, 12 (11), pp.e1005986. ⟨10.1371/journal.ppat.1005986⟩. ⟨hal-02086787⟩
  • Nguyen-Chi Mai, Laplace-Builhé Béryl, Jorgensen Christian, Farida Djouad. Deciphering the complexity of macrophage biology and function with the zebrafish model. Macrophage, 2016, 3, ⟨10.14800/Macrophage.1260⟩. ⟨hal-02097516⟩
  • Mai Nguyen-Chi, Béryl Laplace-Builhé, Jana Travnickova, Patricia Luz-Crawford, Gautier Tejedor, et al.. Identification of polarized macrophage subsets in zebrafish. eLife, 2015, 4, ⟨10.7554/eLife.07288⟩. ⟨hal-01834168v2⟩
  • Mai Nguyen Chi, Quang Tien Phan, Catherine Suarez Dormoy Gonzalez, Jean François Dubremetz, Jean-Pierre Levraud, et al.. Transient infection of the zebrafish notochord with E. coli induces chronic inflammation. Disease Models & Mechanisms, 2014, 7 (7), pp.871-882. ⟨10.1242/dmm.014498⟩. ⟨hal-02088301⟩
  • Mai Nguyen-Chi, Robert Bryson-Richardson, Carmen Sonntag, Thomas E Hall, Abigail Gibson, et al.. Morphogenesis and Cell Fate Determination within the Adaxial Cell Equivalence Group of the Zebrafish Myotome. PLoS Genetics, 2012, 8 (10), pp.e1003014. ⟨10.1371/journal.pgen.1003014⟩. ⟨hal-02097514⟩
  • Mai Nguyen Chi, Jacques Auriol, Bernard Jégou, Dimitris L. Kontoyiannis, James M. A. Turner, et al.. The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages.. Molecular Biology of the Cell, 2011, 22 (16), pp.2875-85. ⟨10.1091/mbc.E11-03-0212⟩. ⟨hal-00682606⟩
  • Mai Nguyen Chi, Frédéric Chalmel, Eric Agius, Nathalie Vanzo, Khalid S. A. Khabar, et al.. Temporally regulated traffic of HuR and its associated ARE-containing mRNAs from the chromatoid body to polysomes during mouse spermatogenesis.. PLoS ONE, Public Library of Science, 2009, 4 (3), pp.e4900. ⟨10.1371/journal.pone.0004900⟩. ⟨inserm-00516318⟩

Conference papers2 documents

  • B Laplace-Builhe, Mai Nguyen-Chi, J Travnickova, C Luz-Crawford, G. Tejedor, et al.. Pro-inflammatory macrophages mediated TNF-alpha signalling is required for caudal fin regenerationin zebrafish larvae. ANNALS OF THE RHEUMATIC DISEASES, Mar 2015, London, United Kingdom. pp.A16.1 - A16, ⟨10.1136/annrheumdis-2015-207259.37⟩. ⟨hal-01834525⟩
  • Mai Nguyen-Chi, B Laplace-Builhe, J Travnickova, C Luz-Crawford, G. Tejedor, et al.. Identification of macrophage subsets in zebrafish larvae. ANNALS OF THE RHEUMATIC DISEASES, Mar 2015, London, United Kingdom. pp.A8.2 - A8, ⟨10.1136/annrheumdis-2015-207259.19⟩. ⟨hal-01834463⟩

Preprints, Working Papers, ...2 documents

  • Sem Jacobs, Éva Dóró, Ffion Hammond, Mai Nguyen-Chi, Georges Lutfalla, et al.. Differential response of macrophages and neutrophils to trypanosome infections in zebrafish: occurrence of foamy macrophages. 2020. ⟨hal-02998164⟩
  • Jana Travnickova, Sandra Nhim, Naoill Abdellaoui, Farida Djouad, Mai Nguyen-Chi, et al.. Macrophage plasticity is Rac signalling and MMP9 dependant. 2019. ⟨hal-02106150⟩