Mariano Ostuni

45
Documents

Publications

Publications

Pharmacological inhibition of polrmt mimicking polrmt rare variants associated with sideroblastic anemia, strongly inhibits proliferation and differentiation of human erythroblasts

Ophélie Evrard , Cécile Deleschaux , Sophie Lefevre , Hakim Ouled-Haddou , Jessica Platon et al.
Blood, 2025, 146 (Supplement 1), pp.4658-4658. ⟨10.1182/blood-2025-4658⟩
Article dans une revue hal-05413691 v1
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Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state

Marc Romana , Sandrine Laurance , Marie‐dominique Hardy-Dessources , Laetitia Claer , Sylvie Ravion et al.
HemaSphere, 2024, 8 (11), ⟨10.1002/hem3.70030⟩
Article dans une revue hal-04774791 v1
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Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state

Marc Romana , Sandrine Laurance , Marie‐dominique Hardy-Dessources , Laetitia Claer , Sylvie Ravion et al.
HemaSphere, 2024, 8 (11), ⟨10.1002/hem3.70030⟩
Article dans une revue hal-05431607 v1
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Physiology of Red Cell Lineage: From Erythroblast Progenitors to Mature Red Blood Cell

Sarah Ducamp , Mariano A. Ostuni
International Journal of Molecular Sciences, 2023, 24 (11), pp.9715. ⟨10.3390/ijms24119715⟩
Article dans une revue hal-05331834 v1
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Oxidative Stress in Healthy and Pathological Red Blood Cells

Florencia Orrico , Sandrine Laurance , Ana C Lopez , Sophie D Lefevre , Leonor Thomson et al.
Biomolecules, 2023, 13 (8), pp.1262. ⟨10.3390/biom13081262⟩
Article dans une revue hal-04964116 v1
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Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells

Sarah Rougé , Sandrine Genetet , Maria Florencia Leal Denis , Michael Dussiot , Pablo Julio Schwarzbaum et al.
International Journal of Molecular Sciences, 2022, 23 (16), pp.9401. ⟨10.3390/ijms23169401⟩
Article dans une revue hal-05331819 v1
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Transmission Electron Microscopy to Follow Ultrastructural Modifications of Erythroblasts Upon ex vivo Human Erythropoiesis

Alice Dussouchaud , Julieta Jacob , Charles Secq , Jean-Marc Verbavatz , Martina Moras et al.
Frontiers in Physiology, 2022, 12, pp.791691. ⟨10.3389/fphys.2021.791691⟩
Article dans une revue hal-05331816 v1
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The permeability of human red blood cell membranes to hydrogen peroxide is independent of aquaporins

Florencia Orrico , Ana C Lopez , Daniela Saliwonczyk , Cecilia Acosta , Ismael Rodriguez-Grecco et al.
Journal of Biological Chemistry, 2022, 298 (1), pp.101503. ⟨10.1016/j.jbc.2021.101503⟩
Article dans une revue hal-05331813 v1
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Interactive Dynamics of Cell Volume and Cell Death in Human Erythrocytes Exposed to α-Hemolysin from Escherichia coli

Nicolas Saffioti , Natalia Lauri , Lucia Cané , Rodolfo Gonzal-Lebrero , Karina Alleva et al.
International Journal of Molecular Sciences, 2022, 23 (2), pp.872. ⟨10.3390/ijms23020872⟩
Article dans une revue hal-03651508 v1
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Homeostasis of extracellular ATP in uninfected RBCs from a Plasmodium falciparum culture and derived microparticles

Cora L Alvarez , Arnaud Chêne , Jean-Philippe Semblat , Benoît Gamain , Claudine Lapouméroulie et al.
Biochimica et Biophysica Acta:Biomembranes, 2022, 1864, ⟨10.1016/j.bbamem.2022.183980⟩
Article dans une revue hal-05331833 v1
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Deficient mitophagy pathways in sickle cell disease

Suella Martino , Jean‐benoit Arlet , Marie‐hélène Odièvre , Vincent Jullien , Martina Moras et al.
British Journal of Haematology, 2021, 193 (5), pp.988-993. ⟨10.1111/bjh.17416⟩
Article dans une revue hal-05521999 v1
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Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance

Martina Moras , Claude Hattab , Pedro Gonzalez-Menendez , Claudio Fader , Michael Dussiot et al.
Article dans une revue halshs-03429293 v1
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CX3CL1 homo-oligomerization drives cell-to-cell adherence

Mariano A. Ostuni , Patricia Hermand , Emeline Saindoy , Noëlline Guillou , Julie Guellec et al.
Scientific Reports, 2020, 10 (1), pp.9069. ⟨10.1038/s41598-020-65988-w⟩
Article dans une revue inserm-02877584 v1
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An Overview of Different Strategies to Recreate the Physiological Environment in Experimental Erythropoiesis

Cécile Deleschaux , Martina Moras , Sophie D Lefevre , Mariano A. Ostuni
International Journal of Molecular Sciences, 2020, 21 (15), pp.5263. ⟨10.3390/ijms21155263⟩
Article dans une revue hal-05331772 v1
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TSPO2 translocates 5‐aminolevulinic acid into human erythroleukemia cells

Hana Manceau , Sophie Lefevre , Arienne Mirmiran , Claude Hattab , Hugo R Sugier et al.
Biology of the Cell, In press, ⟨10.1111/boc.201900098⟩
Article dans une revue hal-02490892 v1
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Downregulation of Mitochondrial TSPO Inhibits Mitophagy and Reduces Enucleation During Human Terminal Erythropoiesis

Martina Moras , Claude Hattab , Pedro Gonzalez-Menendez , Suella Martino , Jerome Larghero et al.
International Journal of Molecular Sciences, 2020, 21 (23), pp.9066. ⟨10.3390/ijms21239066⟩
Article dans une revue hal-03384776 v1
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Induction of ATP Release, PPIX Transport, and Cholesterol Uptake by Human Red Blood Cells Using a New Family of TSPO Ligands

Irene Marginedas-Freixa , Cora L Alvarez , Martina Moras , Claude Hattab , Guillaume Bouyer et al.
International Journal of Molecular Sciences, 2018, 19 (10), pp.3098. ⟨10.3390/ijms19103098⟩
Article dans une revue hal-01926983 v1
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ATPe Dynamics in Protozoan Parasites. Adapt or Perish

Natalia Lauri , Zaher Bazzi , Cora L Alvarez , María F Leal Denis , Julieta Schachter et al.
Genes, 2018, 10 (1), pp.16. ⟨10.3390/genes10010016⟩
Article dans une revue hal-05431606 v1
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From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals

Martina Moras , Sophie D Lefevre , Mariano A. Ostuni
Frontiers in Physiology, 2017, 8, pp.1076. ⟨10.3389/fphys.2017.01076⟩
Article dans une revue hal-05331766 v1
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TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood

I Marginedas-Freixa , C Hattab , G Bouyer , F Halle , A Chene et al.
Scientific Reports, 2016, 6, pp.33516 ⟨10.1038/srep33516⟩
Article dans une revue hal-01369499 v1
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TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood

I Marginedas-Freixa , C Hattab , G Bouyer , F Halle , A Chene et al.
Scientific Reports, 2016, 6, ⟨10.1038/srep33516⟩
Article dans une revue hal-05431604 v1
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Rat submandibular glands secrete nanovesicles with NTPDase and 5′-nucleotidase activities

Débora A González , Patricia Egido , Noelia B Balcarcel , Claude Hattab , Martín M Barbieri van Haaster et al.
Purinergic Signalling, 2015, 11 (1), pp.107-116. ⟨10.1007/s11302-014-9437-0⟩
Article dans une revue hal-05363754 v1
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Construction and validation of an atomic model for bacterial TSPO from electron microscopy density, evolutionary constraints, and biochemical and biophysical data

Konrad Hinsen , Aurore Vaitinadapoule , Mariano A. Ostuni , Catherine Etchebest , Jean-Jacques Lacapere
Biochimica et Biophysica Acta:Biomembranes, 2015, 1848 (2), pp.568-580. ⟨10.1016/j.bbamem.2014.10.028⟩
Article dans une revue istex hal-05431600 v1

Construction and validation of an atomic model for bacterial TSPO from electron microscopy density, evolutionary constraints, and biochemical and biophysical data.

Konrad Hinsen , Aurore Vaitinadapoule , Mariano A. Ostuni , Catherine Etchebest , Jean-Jacques Lacapere
Biochimica et Biophysica Acta:Biomembranes, 2015, 1848 (2), pp.568-580. ⟨10.1016/j.bbamem.2014.10.028⟩
Article dans une revue istex hal-01171268 v1
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Translocator Protein-Mediated Stabilization of Mitochondrial Architecture during Inflammation Stress in Colonic Cells.

Leeyah Issop , Mariano A Ostuni , Sunghoon Lee , Mireille Laforge , Gabriel Péranzi et al.
PLoS ONE, 2015, 11 (4), pp.e0152919. ⟨10.1371/journal.pone.0152919⟩
Article dans une revue hal-01302159 v1
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CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain

Mariano A. Ostuni , Julie Guellec , Patricia Hermand , Pauline Durand , Christophe Combadière et al.
Biology Open, 2014, 3, pp.1173-1182. ⟨10.1242/bio.20149845⟩
Article dans une revue inserm-01095507 v1
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CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain

Mariano A. Ostuni , Julie Guellec , Patricia Hermand , Pauline Durand , Christophe Combadière et al.
Biology Open, 2014, 3 (12), pp.1173-1182. ⟨10.1242/bio.20149845⟩
Article dans une revue hal-05431601 v1
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Effect of translocator protein (18 kDa)‐ligand binding on neurotransmitter‐induced salivary secretion in rat submandibular glands

Mariano A. Ostuni , Omar Tumilasci , Gabriel Péranzi , Estela Cardoso , Liliana Contreras et al.
Biology of the Cell, 2012, 100 (7), pp.427-439. ⟨10.1042/BC20070157⟩
Article dans une revue hal-05452265 v1
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trans Arachidonic acid isomers inhibit NADPH-oxidase activity by direct interaction with enzyme components

H. Souabni , V. Thoma , Tania Bizouarn , C. Chatgilialoglu , A. Siafaka-Kapadai et al.
Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (9), pp.2314-2324. ⟨10.1016/j.bbamem.2012.04.018⟩
Article dans une revue hal-05331761 v1
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Distribution, pharmacological characterization and function of the 18 kDa translocator protein in rat small intestine

Mariano Anibal Ostuni , Gabriel Péranzi , Robert Ducroc , Magali Fasseu , Branislav Vidic et al.
Biology of the Cell, 2012, 101 (10), pp.573-586. ⟨10.1042/BC20080231⟩
Article dans une revue hal-05452296 v1
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Combinatorial Discovery of Fluorescent Pharmacophores by Multicomponent Reactions in Droplet Arrays

Olga Burchak , Laurent Mugherli , Mariano A. Ostuni , Jean Jacques Lacapère , Maxim Balakirev
Journal of the American Chemical Society, 2011, 133 (26), pp.10058-10061. ⟨10.1021/ja204016e⟩
Article dans une revue hal-05521965 v1
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Overexpression of translocator protein in inflammatory bowel disease: Potential diagnostic and treatment value

Mariano A. Ostuni , Leeyah Issop , Gabriel Péranzi , Francine Walker , Magali Fasseu et al.
Inflammatory Bowel Diseases, 2010, 16 (9), pp.1476-1487. ⟨10.1002/ibd.21250⟩
Article dans une revue hal-05431599 v1
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TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition.

Sophie Schaller , Stéphanie Paradis , Gladys A. Ngoh , Rana Assaly , Bruno Buisson et al.
Journal of Pharmacology and Experimental Therapeutics, 2010, 333 (3), pp.696-706. ⟨10.1124/jpet.110.167486⟩
Article dans une revue inserm-00497589 v1

Expression of functional mammal flavocytochrome b(558) in yeast: comparison with improved insect cell system.

Mariano A. Ostuni , Leila B. Lamanuzzi , Tania Bizouarn , Marie-Claire Dagher , Laura Baciou
BBA - Biochimica et Biophysica Acta, 2010, 1798 (6), pp.1179-88. ⟨10.1016/j.bbamem.2010.02.016⟩
Article dans une revue hal-00820712 v1
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Modulation of the activity of the NADPH oxidase system by reactive oxygen species: influence of catalase

Mariano A. Ostuni , T. Bizouarn , L. Baciou , C. Houee-Levin
Radiation Protection Dosimetry, 2010, 143 (2-4), pp.166-171. ⟨10.1093/rpd/ncq518⟩
Article dans une revue hal-05521957 v1
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Expression of functional mammal flavocytochrome b558 in yeast: Comparison with improved insect cell system

Mariano A. Ostuni , Leila B Lamanuzzi , Tania Bizouarn , Marie-Claire Dagher , Laura Baciou
Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (6), pp.1179-1188. ⟨10.1016/j.bbamem.2010.02.016⟩
Article dans une revue hal-05431596 v1
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Expression of functional mammal flavocytochrome b558 in yeast: Comparison with improved insect cell system

Mariano A. Ostuni , Leila Lamanuzzi , Tania Bizouarn , Marie-Claire Dagher , Laura Baciou
Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (6), pp.1179-1188. ⟨10.1016/j.bbamem.2010.02.016⟩
Article dans une revue hal-05452317 v1
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Translocator protein (18 kDa) is involved in primitive erythropoiesis in zebrafish

Christine Rampon , Mohamed Rouzaffour , Mariano A. Ostuni , Pascale Dufourcq , Christelle Girard et al.
FASEB Journal, 2009, 23 (12), pp.4181-4192. ⟨10.1096/fj.09-129262⟩
Article dans une revue hal-05452304 v1
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Characterization of a functional NTPDase in the endoplasmic reticulum of rat submandibular salivary gland

Mariano A. Ostuni , P Egido , G Peranzi , Gl Alonso , J-J Lacapere et al.
Physiological Research, 2009, 58 (6), pp.843-854. ⟨10.33549/physiolres.931682⟩
Article dans une revue hal-05324635 v1
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Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

Samuel Murail , Jean-Claude Robert , Yves-Marie Coïc , Jean-Michel Neumann , Mariano A Ostuni et al.
Biochimica et Biophysica Acta:Biomembranes, 2008, 1778 (6), pp.1375-1381. ⟨10.1016/j.bbamem.2008.03.012⟩
Article dans une revue hal-05440360 v1
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Stoichiometry of ATP and metal cofactor interaction with the sarcoplasmic reticulum Ca2+–ATPase: A binding model accounting for radioisotopic and fluorescence results

Débora A González , Mariano A. Ostuni , Jean-Jacques Lacapère , Guillermo L Alonso
Biophysical Chemistry, 2006, 124 (1), pp.27-34. ⟨10.1016/j.bpc.2006.05.025⟩
Article dans une revue hal-05324364 v1
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STANDARDIZATION OF A SIMPLE METHOD TO STUDY WHOLE SALIVA: CLINICAL USE IN DIFFERENT PATHOLOGIES

Omar René Tumilasci , Estela M. L. Cardoso , Liliana N. Contreras , Juan Belforte , Alejandro L. Arregger et al.
Acta odontologica latinoamericana : AOL, 2006, 19 (2), pp.47-51
Article dans une revue hal-05324342 v1
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Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor

Nadège Jamin , Jean-Michel Neumann , Mariano A. Ostuni , Thi Kim Ngoc Vu , Zhi-Xing Yao et al.
Molecular Endocrinology, 2005, 19 (3), pp.588-594. ⟨10.1210/me.2004-0308⟩
Article dans une revue hal-05324303 v1
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Functional characterization and expression of PBR in rat gastric mucosa: stimulation of chloride secretion by PBR ligands

Mariano A. Ostuni , K. Marazova , G. Peranzi , B. Vidic , V. Papadopoulos et al.
AJP - Gastrointestinal and Liver Physiology, 2004, 286 (6), pp.G1069-G1080. ⟨10.1152/ajpgi.00290.2003⟩
Article dans une revue hal-05431591 v1

Calcium additional to that bound to the transport sites is required for full activation of the sarcoplasmic reticulum Ca-ATPase from skeletal muscle

Guillermo Alonso , Débora González , Delia Takara , Mariano A. Ostuni , Gabriel Sánchez
Biochimica et Biophysica Acta - Molecular Cell Research, 1998, 1405 (1-3), pp.47-54. ⟨10.1016/s0167-4889(98)00101-3⟩
Article dans une revue istex hal-05431589 v1