Marie Bodinier
- Unité de recherche sur les Biopolymères, Interactions Assemblages (BIA)
Présentation
Dr Marie Bodinier, (BSc, BND, PhD) is research director (DR2) at INRAE Pays de la Loire, BIA unit, Allergy team. She is a qualified immunologist and researcher with a great expertise in allergic disease. She is head of the Allergy Team which houses a plethora of complementary expertises (food and immunology) with a common aim : reduce and prevent allergic risk. She organizes the team through meetings, budget acquisition and management, response strategy to calls for tender and management of personnel (2CR, 2 DR, 3 TR and 5 non-permanents). She is leading translational research to understand the early mechanisms of allergy development and to establish perinatal nutritional strategies for allergy prevention. Currently, she is scientific coordinator of the clinical trial PREGRALL (clinical trial : NCT03183440, 2018-2021) (36) and the ancillary study CIMMAP funded by ANR. She is responsible for the allergy topic in the scientific committee of the Research Center in Human Nutrition - West (CRNH-O) : a Public Interest Group. She is a member of the scientific committee of the French Society of Nutrition since 2017 and the working group on Food Allergy of the French Society of Allergy (SFA) since 2019. In 2016, she performed a mission abroad of one year in the CAIR Team with S. Prescott and D. Palmer (Telethon Kids Institute, Perth AUSTRALIA) to follow the SYMBA trial project (the homologue of PREGRALL, Australian New Zealand Clinical Trial Registry : ACTRN12615001075572, (41)), to increase her expertise in translational research and to improve her international network. She has been involved in 27 research projects (20 national, 3 European and 4 industrial projects) including 13 in coordination. M Bodinier manages the ANR project CIMMAP (end of the project : March 2024, currently 5 publications) of 1034 k€ involving 7 partners, who will also be involved in the PREBIATOP project. She is the author of 44 peer-reviewed publications referenced in HAL (https://orcid.org/0000-0001-5983-4657), 9 articles in professional journals, 2 book chapters on allergies and microbiota and prebiotics and made 101 oral presentations at national or international conferences. She has a patent (Patent INSERM FR2798128) and a license for industrial exploitation with a product dedicated to the market of fundamental research and clinic (diagnosis and therapy). She supervised 25 students including 7 doctoral students and 6 postdoctoral fellows.
Domaines de recherche
Compétences
Publications
Publications
Régulations immunologiques d'une supplémentation en prébiotiques (GOS/Inuline) pendant la grossesse pour la prévention de la dermatite atopique chez l'enfant.Congrès Francophone d’Allergologie (CFA), Apr 2024, Paris, France |
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La supplémentation maternelle en prébiotiques pendant la grossesse régule la colonisation du microbiote des enfants à haut risque, mais ne permet pas de prévenir la dermatite atopique à l’âge d’un anCFA, Apr 2024, Paris, France |
Impact of prebiotic supplementation during pregnancy on food allergy development in offspring.EAACI meeting, Digital LONDON, GBR (2020-06-06 – 2020-06-08)., Jun 2020, London, United Kingdom |
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Modulation of the immune system in feto-maternel tissues by prebiotics supplementation during pregnancy : a future strategy for allergy preventionWorld of Microbiome Conference, Oct 2019, Milan (Italie), Italy |
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Impact of prebiotic supplementation during pregnancy on food allergy development in offspringWorld of Microbiome Conference,, Oct 2019, Milan, Italy |
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Impact of different polyphenols on wheat allergic response in in vitro and in vivo models32nd EFFoST International Conference 2018, Nov 2018, Nantes, France |
Perinatal exposure to galactooligosaccharides/inulin prebiotics prevent food allergy by protecting intestine and promoting toleranceCongress of the European-Academy-of-Allergy-and-Clinical-Immunology, Jun 2015, Barcelone, Spain. Allergy, 70, 1 p., 2015 |
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Perinatal exposure to galactooligosaccharides/inulin prebiotics prevent food allergy by protecting intestine and promoting tolerance2. Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS) Cytokines Down Under, Oct 2014, Melbourne, Australia. Cytokine, 70, pp.28-79, 2014, ⟨10.1016/j.cyto.2014.07.018⟩ |
A first sensitisation to food allergen induces an aggravation of asthmatic phenotype in a house dust mite asthmatic modelEuropean Academy of Allergy and Clinical Immunology and World Allergy Organization World Allergy and Asthma Congress, Jun 2013, Milan, Italy. Wiley-Blackwell, Allergy, 68 (Suppl. 97), 744 p., 2013, Abstracts from the European Academy of Allergy and Clinical Immunology and World Allergy Organization World Allergy and Asthma Congress |
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Study of immuno-physiological mechanism implicated in atopic march using an original mouse model of food and respiratory combined allergyEuropean Academy of Allergy and Clinical Immunology and World Allergy Organization World Allergy and Asthma Congress, Jun 2013, Milan, Italy. Wiley-Blackwell, Allergy, 68 (Suppl. 97), 744 p., 2013, Abstracts from the European Academy of Allergy and Clinical Immunology and World Allergy Organization World Allergy and Asthma Congress |
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Impact of the exposure period to GOS/inulin prebiotics on immune system orientation31. Congress of the European Academy of Allergy and Clinical Immunology, Jun 2012, genève, Switzerland. pp.1, 2012 |
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Effet de la période d’exposition à un mélange de prébiotiques sur l’orientation du système immunitaire7. Congrès Francophone d’Allergologie, Apr 2012, Paris, France. 2012 |
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Des prébiotiques capables d’induire des mécanismes de tolérance sans réduire les symptômes d’allergie chez la souris6. Congrès Francophone d'Allergologie, Apr 2011, Paris, France. 2011 |
IgE-binding epitopes on wheat LTP1 for patients with food allergy to wheat and experimentally sensitized mice4. International Symposium on Molecular Allergology ISMA 2010, Oct 2010, Munich, Germany. , 2010 |
A new combination of probiotics and prebiotics attenuates symptoms in a mouse food allergy modelAllergy, 72 (103), pp.479-480, 2017 |
Chapitre II. Microbiote et pathologie : 16. Microbiote et allergies de l’ouvrage « Microbiote intestinal et Santé humaine ».Elsevier Masson. Microbiote intestinal et Santé humaine, 2021, 9782294769306 | |
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PrébiotiquesAliments fonctionnels dans un système alimentaire sain et durable, Coll. Sciences et techniques agroalimentaires, Lavoisier Tec & Doc, 2019 |
Compte-rendu de fin de projet ANR: Projet ANR- 17-CE17-0022 CIMMAPinrae pays de la loire UR1268 BIA. 2024 |
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Document de synthèse du groupe de travail "enjeux et questions de recherche sur protéines végétales communes entre les départements TRANSFORM & BAP[Rapport Technique] Inrae. 2021 |
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Allergies alimentaires IgE et non-IgE médiéesMaster. Master 1 d'allergologie, Nantes Faculté de Médecine, France. 2019 |