Marie-Clotilde ALVES-GUERRA

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Publications

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Iron Boosts Antitumor Type 1 T-cell Responses and Anti-PD1 Immunotherapy

Sarah Porte , Alexandra Audemard-Verger , Christian Wu , Aurélie Durand , Théo Level et al.

Cancer Immunology Research, 2024, 12 (9), pp.1252-1267. ⟨10.1158/2326-6066.CIR-23-0739⟩

Article dans une revue hal-04736166v1
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The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

Emmanuel Benichou , Bolaji Seffou , Selin Topçu , Ophélie Renoult , Véronique Lenoir et al.

Nature Communications, 2024, Nature Communications, 15 (1), pp.1879. ⟨10.1038/s41467-024-45548-w⟩

Article dans une revue hal-04696163v1
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Mitochondrial metabolism sustains CD8+ T cell migration for an efficient infiltration into solid tumors

Luca Simula , Mattia Fumagalli , Lene Vimeux , Irena Rajnpreht , Philippe Icard et al.

Nature Communications, 2024, 15, pp.2203. ⟨10.1038/s41467-024-46377-7⟩

Article dans une revue hal-04598718v1
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UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling

Tiphaine Sancerni , Ophélie Renoult , Angèle Luby , Cédric Caradeuc , Véronique Lenoir et al.

Frontiers in Immunology, 2022, 13, pp.960226. ⟨10.3389/fimmu.2022.960226⟩

Article dans une revue hal-03817349v1
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UCP2 as a Cancer Target through Energy Metabolism and Oxidative Stress Control

Angèle Luby , Marie-Clotilde Alves-Guerra

International Journal of Molecular Sciences, 2022, 23 (23), pp.15077. ⟨10.3390/ijms232315077⟩

Article dans une revue hal-03886848v1
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Targeting Metabolism to Control Immune Responses in Cancer and Improve Checkpoint Blockade Immunotherapy

Angèle Luby , Marie-Clotilde Alves-Guerra

Cancers, 2021, 13 (23), pp.5912. ⟨10.3390/cancers13235912⟩

Article dans une revue hal-03798523v1
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Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2

Giulia Bertolin , Marie-Clotilde Alves-Guerra , Angélique Chéron , Agnès Burel , Claude Prigent et al.

Life Science Alliance, 2021, 4 (6), pp.e202000806. ⟨10.26508/lsa.202000806⟩

Article dans une revue hal-03248135v1
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The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance

Xanthe A.M.H. van Dierendonck , Tiphaine Sancerni , Marie-Clotilde Alves-Guerra , Rinke Stienstra

Journal of Biological Chemistry, 2020, 295 (51), pp.17535-17548. ⟨10.1074/jbc.RA120.014868⟩

Article dans une revue hal-03418808v1
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Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target

Delphine Garnier , Ophélie Renoult , Marie-Clotilde Alves-Guerra , François Paris , Claire Pecqueur

Frontiers in Oncology, 2019, 9, pp.118. ⟨10.3389/fonc.2019.00118⟩

Article dans une revue inserm-02240417v1
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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

Esther Aguilar , Pauline Esteves , Tiphaine Sancerni , Véronique Lenoir , Thomas Aparicio et al.

Cell Reports, 2019, 28 (9), pp.2306-2316.e5. ⟨10.1016/j.celrep.2019.07.097⟩

Article dans une revue inserm-02345411v1
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β-catenin-activated hepatocellular carcinomas are addicted to fatty acids

Nadia Senni , Mathilde Savall , David Cabrerizo Granados , Marie-Clotilde Alves-Guerra , Chiara Sartor et al.

Gut, 2019, 68 (2), pp.322-334. ⟨10.1136/gutjnl-2017-315448⟩

Article dans une revue inserm-02532896v1

β-catenin-activated hepatocellular carcinomas are addicted to fatty acids

Nadia Senni , Mathilde Savall , David Cabrerizo Granados , Marie-Clotilde Alves-Guerra , Chiara Sartor et al.

Gut, 2019, 68 (2), pp.322-334. ⟨10.1136/gutjnl-2017-315448⟩

Article dans une revue hal-02347077v1
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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Julien Bricambert , Marie-Clotilde Alves-Guerra , Pauline Esteves , Carina Prip-Buus , Justine Bertrand-Michel et al.

Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩

Article dans une revue hal-02122655v1
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Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

Giulia Bertolin , Anne-Laure Bulteau , Marie-Clotilde Alves-Guerra , Agnes Burel , Marie-Thérèse Lavault et al.

eLife, 2018, 7, pp.e38111. ⟨10.7554/eLife.38111⟩

Article dans une revue hal-01862597v1

The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice

Misa Hirose , Paul Schilf , Sarah Rohde , Yask Gupta , Tiphaine Sancerni et al.

Mitochondrion, 2018, 42, pp.50-53. ⟨10.1016/j.mito.2017.10.011⟩

Article dans une revue hal-02347089v1
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Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation

Audrey Lafargue , Charlotte Degorre , Isabelle Corre , Marie-Clotilde Alves-Guerra , Marie-Hélène Gaugler et al.

Free Radical Biology and Medicine, 2017, 108, pp.750-759. ⟨10.1016/j.freeradbiomed.2017.04.019⟩

Article dans une revue inserm-01514403v1
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Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity

Kristell Oizel , Cynthia Chauvin , Lisa Oliver , Catherine Gratas , Fanny Geraldo et al.

Clinical Cancer Research, 2017, 23 (20), ⟨10.1158/1078-0432.CCR-16-3102⟩

Article dans une revue inserm-01595798v1
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Mitochondrial Protein UCP2 Controls Pancreas Development

Benjamin Broche , Selma Ben Fradj , Esther Aguilar , Tiphaine Sancerni , Matthieu Bénard et al.

Diabetes, 2017, 67 (1), pp.78-84. ⟨10.2337/db17-0118⟩

Article dans une revue hal-02347094v1

Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance

Eliska Vavrova , Véronique Lenoir , Marie-Clotilde Alves-Guerra , Raphaël G. P. Denis , Julien Castel et al.

AJP - Endocrinology and Metabolism, 2016, 311 (3), pp.E649-E660. ⟨10.1152/ajpendo.00020.2016⟩

Article dans une revue hal-02347127v1

UCPs, at the interface between bioenergetics and metabolism

Frédéric Bouillaud , Marie-Clotilde Alves-Guerra , Daniel Ricquier

Biochimica et Biophysica Acta - Molecular Cell Research, 2016, 1863 (10), pp.2443-2456. ⟨10.1016/j.bbamcr.2016.04.013⟩

Article dans une revue hal-02347140v1

NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis

Kelly Weaver , Marie-Clotilde Alves-Guerra , Ke Jin , Zhiqiang Wang , Xiaoqing Han et al.

Cancer Research, 2014, 74 (17), pp.4741-4751. ⟨10.1158/0008-5472.CAN-14-1547⟩

Article dans une revue hal-02347171v1
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UCP2 induces metabolic reprogramming to inhibit proliferation of cancer cells

Esteves Pauline , Claire Pecqueur , Alves-Guerra Marie-Clotilde

Molecular & Cellular Oncology, 2014, 2 (1), ⟨10.4161/23723556.2014.975024⟩

Article dans une revue inserm-01207304v1
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Analysis of Uncoupling Protein 2-Deficient Mice upon Anaesthesia and Sedation Revealed a Role for UCP2 in Locomotion

Marie-Clotilde Alves-Guerra , Caroline Aheng , Claire Pecqueur , Sandrine Masscheleyn , Pierre Louis Tharaux et al.

PLoS ONE, 2012, 7 (8), pp.e41846. ⟨10.1371/journal.pone.0041846⟩

Article dans une revue hal-02347202v1

Deletion of UCP2 in iNOS Deficient Mice Reduces the Severity of the Disease during Experimental Autoimmune Encephalomyelitis

Caroline Aheng , Nathalie Ly , Mairead Kelly , Saleh Ibrahim , Daniel Ricquier et al.

PLoS ONE, 2011, 6 (8), pp.e22841. ⟨10.1371/journal.pone.0022841⟩

Article dans une revue hal-02347213v1

UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?

Claire Pecqueur , Clotilde Alves-Guerra , Daniel Ricquier , Frédéric Bouillaud

IUBMB Life, 2009, 61 (7), pp.762-767. ⟨10.1002/iub.188⟩

Article dans une revue hal-02347239v1

UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?

Claire Pecqueur , Clotilde Alves-Guerra , Daniel Ricquier , Frederic Bouillaud

IUBMB Life, 2009, 61 (7), pp.762-767. ⟨10.1002/iub.188⟩

Article dans une revue hal-03055035v1

Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival.

Alves-Guerra Marie-Clotilde , Ronchini Chiara , Capobianco Anthony J

Cancer Research, 2007

Article dans une revue hal-02347311v1

Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels

Fabienne de Bilbao , Denis Arsenijevic , Philippe Vallet , Ole Petter Hjelle , Ole Petter Ottersen et al.

Journal of Neurochemistry, 2004, 89 (5), pp.1283-1292. ⟨10.1111/j.1471-4159.2004.02432.x⟩

Article dans une revue hal-03054815v1

Uncoupling Protein 2, but Not Uncoupling Protein 1, Is Expressed in the Female Mouse Reproductive Tract

Sophie Rousset , Marie-Clotilde Alves-Guerra , Salma Ouadghiri-Bencherif , Leslie Kozak , Bruno Miroux et al.

Journal of Biological Chemistry, 2003, 278 (46), pp.45843-45847. ⟨10.1074/jbc.M306980200⟩

Article dans une revue hal-03054599v1

Bone Marrow Transplantation Reveals the in Vivo Expression of the Mitochondrial Uncoupling Protein 2 in Immune and Nonimmune Cells during Inflammation

Marie-Clotilde Alves-Guerra , Sophie Rousset , Claire Pecqueur , Ziad Mallat , Julie Blanc et al.

Journal of Biological Chemistry, 2003, 278 (43), pp.42307-42312. ⟨10.1074/jbc.M306951200⟩

Article dans une revue hal-03054592v1

Uncoupling Protein 2, in Vivo Distribution, Induction upon Oxidative Stress, and Evidence for Translational Regulation

Claire Pecqueur , Marie-Clotilde Alves-Guerra , Chantal Gelly , Corinne Lévi-Meyrueis , Elodie Couplan et al.

Journal of Biological Chemistry, 2001, 276 (12), pp.8705-8712. ⟨10.1074/jbc.M006938200⟩

Article dans une revue hal-03054560v1

Transcriptional Activation of the Human ucp1 Gene in a Rodent Cell Line

Maria del Mar Gonzalez-Barroso , Claire Pecqueur , Chantal Gelly , Daniel Sanchis , Marie-Clotilde Alves-Guerra et al.

Journal of Biological Chemistry, 2000, 275 (41), pp.31722-31732. ⟨10.1074/jbc.M001678200⟩

Article dans une revue hal-03054399v1

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

Denis Arsenijevic , Hiroki Onuma , Claire Pecqueur , Serge Raimbault , Brian Manning et al.

Nature Genetics, 2000, 26 (4), pp.435-439. ⟨10.1038/82565⟩

Article dans une revue hal-03054550v1