Marie Morille
Présentation
Marie Morille is Associate Professor in Montpellier University (Pharmacy School, Pharmaceutical sciences and Biomaterials Department) and Institute of Regenerative Medicine and Biotherapies (Inserm U1183) . During her phD and post-doctoral research, she worked on formulation of nano/microcarriers (surface functionalization, nucleic acids/protein loading) with a special care on coordination between carriers physico-chemical properties and impact on biological behaviour (in vitro/in vivo). As a result, she developed a multidisciplinary expertise at the interface of physico-chemistry, galenics and biology, which is particularly stimulating and allows me to interact with very different scientific backgrounds. In ICGM, she focuses on the delivery of biomolecules (nucleic acids, proteins) for health applications (cancerology, tissue engineering) using nanocarriers (lipid/polymer based). Since 2016, she has developed a line of research based on pharmaceutical sciences applied to Mesenchymal Stromal Cells (MSC) derived extracellular vesicles (EV), to increase the therapeutic potential of these promising bio/nanomedicines using pharmaceutical and physico-chemical tools/processes (characterization, storage, EV surface modification, EV engineering for biomolecules loading).
Publications
Publications
        
            When polymers meet EVs: interest of EVs’ surface modification with PEG alternatives for in vivo administrationISEV Early Career Researchers network webinar, Feb 2025, Montpellier online, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970930
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            Les vecteurs non viraux dans les thérapies innovantesJournée thématique « Thérapies innovantes », Filière de Santé Maladies Rares Neuromusculaire Filnemus, Paris, 12 Décembre 2024, Feb 2025, Paris, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970917
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            EV engineering : what about numbers?!ISEV (International Society of Extracellular Vesicles) 2024 annual Meeting – Education Day, May 2024, Melbourne (AUS), Australia 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970912
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            Enhancing the therapeutic potential of natural vesicles using pharmaceutical & chemical engineeringInserm Workshop. Advances in therapeutic applications of extracellular vesicles, Jun 2023, Bordeaux, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970863
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            Biochemical Approach using Lipid Anchors to Associate Proteins to Extracellular Vesicles for Intracellular Drug DeliverySFNano Annual Meeting (French Society for Nanomedicine) Dec 2023, Montpellier, France., Dec 2023, Montpellier, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970899
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            Biochemical Association of Proteins to Extracellular Vesicles for intracellular deliveryEVOCC scientific day 2023, Montpellier, Jun 2023, Montpellier, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970854
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            Design of peptide-based and responsive biomaterials23e Rassemblement du Groupe Français des Peptides et Protéines, GFPP, 2023, Fournols, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04852354
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            Use of Lipid Anchors to Associate Proteins and Extracellular Vesicles for Intracellular Drug DeliveryFrench Society of Extracellular Vesicles (FSEV 2023) annual meeting, Nov 2023, Paris, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970885
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            Extracellular vesicle pharmaceutical development to increase extracellular therapeutic potential18èmes Journées Annuelles du Cancéropôle GSO – 2022, Nov 2022, La Grande Motte - Montpellier, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970829
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            Pharmaceutical development to enhance small Extracellular Vesicles (sEV) therapeutic potentialBioregate forum 2022, September, Louvain-la neuve, Sep 2022, Louvain -la-Neuve, Belgium 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970814
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            Différents profils de miRNA sécrétés par le tissu adipeux viscéral de patients obèses présentant différents statuts métaboliquesCongrès annuel 2022 de la Société Francophone du Diabète (SFD 2022), Société Francophone du Diabète (SFD), Mar 2022, Nice, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-05056500
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            Surface modifications of mesenchymal stem cells derived extracellular vesicles for plasma stabilizationSFNano Annual Meeting, 2021, Angers, Dec 2021, Angers, France 
                 Communication dans un congrès
                    
        
        
            
                
                    hal-04970794
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            Spatio-temporal control of cellular differentiation for cartilage tissue engineeringEuropean Peptide Society. 37th European Peptide Symposium (37th EPS) & 14th International Peptide Symposium (14th IPS), Aug 2024, Florence, Italy. Wiley, Journal of Peptide Science, 30 (S2), pp.170-171, 2024 
                 Poster de conférence
                    
        
        
            
                
                    hal-04811378
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            Differential release of miRNAs by visceral adipose tissue from obese patients with various metabolic status56th Annual Meeting of the European Association for the Study of Diabetes (EASD 2020), Sep 2020, Vienne, Austria. Springer, Diabetologia, 63 (suppl. 1), pp.527, 2020 
                 Poster de conférence
                    
        
        
            
                
                    hal-05056458
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            Development of pharmacologically active microcarriers transporting stem cells and releasing growth factors integrated in a thermosensitive injectable hydrogel for an efficient tissue engineering strategyAnnual Meeting Tissue Engineering & Regenerative Medicine (TERMIS), 2011, Houston, United States. 2011 
                 Poster de conférence
                    
        
        
            
                
                    hal-03184060
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            Systemic treatment of ferrocenyl-based drug loaded lipid nanocapsules on a subcutaneous 9L glioma model in rats7th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2010, Valletta, Malte. 2010 
                 Poster de conférence
                    
        
        
            
                
                    hal-03179509
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            Exosomal melanotransferrin as a potential biomarker for metastatic melanoma2021 
                 Pré-publication, Document de travail
                    
        
        
            
                
                    hal-03101491
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            Scaffolds for Controlled Release of Cartilage Growth FactorsScaffolds for Controlled Release of Cartilage Growth Factors, pp.171-180, 2015, ⟨10.1007/978-1-4939-2938-2_12⟩ 
                 Chapitre d'ouvrage
                    
        
        
            
                
                    hal-03212213
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            Near-infrared optical imaging of nucleic acid nanocarriers in vivo.Nanotechnology for Nucleic Acid Delivery, 948, Humana Press, pp.49-65, 2013, ⟨10.1007/978-1-62703-140-0_5⟩ 
                 Chapitre d'ouvrage
                    
        
        
            
                
                    inserm-00874399
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            Near-Infrared Optical Imaging of Nucleic Acid Nanocarriers In VivoNear-Infrared Optical Imaging of Nucleic Acid Nanocarriers In Vivo, pp.49-65, 2013, ⟨10.1007/978-1-62703-140-0_5⟩ 
                 Chapitre d'ouvrage
                    
        
        
            
                
                    hal-03212203
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            Microsphere compositions, preparation method and applications thereofFrance, Patent n° : Non spécifié. 2013 
                 Brevet
                    
        
        
            
                
                    hal-03180823
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            Thérapie génique à l'aide de nanocapsules lipidiques PEGyléesSciences pharmaceutiques. Université d'Angers, 2009. Français. ⟨NNT : ⟩ 
                 Thèse
                    
        
        
            
                
                    tel-00459201
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