
Marie Morille
Présentation
Marie Morille is Associate Professor in Montpellier University (Pharmacy School, Pharmaceutical sciences and Biomaterials Department) and Institute Charles Gerhardt of Montpellier (ICGM) (ORCID; Google Scholar) since 2012. During her phD and post-doctoral research, she worked on formulation of nano/microcarriers (surface functionalization, nucleic acids/protein loading) with a special care on coordination between carriers physico-chemical properties and impact on biological behaviour (in vitro/in vivo). As a result, she developed a multidisciplinary expertise at the interface of physico-chemistry, galenics and biology, which is particularly stimulating and allows me to interact with very different scientific backgrounds. In ICGM, she focuses on the delivery of biomolecules (nucleic acids, proteins) for health applications (cancerology, tissue engineering) using nanocarriers (lipid/polymer based). Since 2016, she has developed a line of research based on pharmaceutical sciences applied to Mesenchymal Stromal Cells (MSC) derived extracellular vesicles (EV), to increase the therapeutic potential of these promising bio/nanomedicines using pharmaceutical and physico-chemical tools/processes (characterization, storage, EV surface modification, EV engineering for biomolecules loading).
Publications
Publications
When polymers meet EVs: interest of EVs’ surface modification with PEG alternatives for in vivo administrationISEV Early Career Researchers network webinar, Feb 2025, Montpellier online, France
Communication dans un congrès
hal-04970930
v1
|
|
Les vecteurs non viraux dans les thérapies innovantesJournée thématique « Thérapies innovantes », Filière de Santé Maladies Rares Neuromusculaire Filnemus, Paris, 12 Décembre 2024, Feb 2025, Paris, France
Communication dans un congrès
hal-04970917
v1
|
|
EV engineering : what about numbers?!ISEV (International Society of Extracellular Vesicles) 2024 annual Meeting – Education Day, May 2024, Melbourne (AUS), Australia
Communication dans un congrès
hal-04970912
v1
|
|
Biochemical Approach using Lipid Anchors to Associate Proteins to Extracellular Vesicles for Intracellular Drug DeliverySFNano Annual Meeting (French Society for Nanomedicine) Dec 2023, Montpellier, France., Dec 2023, Montpellier, France
Communication dans un congrès
hal-04970899
v1
|
|
Biochemical Association of Proteins to Extracellular Vesicles for intracellular deliveryEVOCC scientific day 2023, Montpellier, Jun 2023, Montpellier, France
Communication dans un congrès
hal-04970854
v1
|
|
Enhancing the therapeutic potential of natural vesicles using pharmaceutical & chemical engineeringInserm Workshop. Advances in therapeutic applications of extracellular vesicles, Jun 2023, Bordeaux, France
Communication dans un congrès
hal-04970863
v1
|
|
Design of peptide-based and responsive biomaterials23e Rassemblement du Groupe Français des Peptides et Protéines, GFPP, 2023, Fournols, France
Communication dans un congrès
hal-04852354
v1
|
|
Use of Lipid Anchors to Associate Proteins and Extracellular Vesicles for Intracellular Drug DeliveryFrench Society of Extracellular Vesicles (FSEV 2023) annual meeting, Nov 2023, Paris, France
Communication dans un congrès
hal-04970885
v1
|
|
Extracellular vesicle pharmaceutical development to increase extracellular therapeutic potential18èmes Journées Annuelles du Cancéropôle GSO – 2022, Nov 2022, La Grande Motte - Montpellier, France
Communication dans un congrès
hal-04970829
v1
|
|
Pharmaceutical development to enhance small Extracellular Vesicles (sEV) therapeutic potentialBioregate forum 2022, September, Louvain-la neuve, Sep 2022, Louvain -la-Neuve, Belgium
Communication dans un congrès
hal-04970814
v1
|
|
Différents profils de miRNA sécrétés par le tissu adipeux viscéral de patients obèses présentant différents statuts métaboliquesCongrès annuel 2022 de la Société Francophone du Diabète (SFD 2022), Société Francophone du Diabète (SFD), Mar 2022, Nice, France
Communication dans un congrès
hal-05056500
v1
|
|
Surface modifications of mesenchymal stem cells derived extracellular vesicles for plasma stabilizationSFNano Annual Meeting, 2021, Angers, Dec 2021, Angers, France
Communication dans un congrès
hal-04970794
v1
|
Spatio-temporal control of cellular differentiation for cartilage tissue engineeringEuropean Peptide Society. 37th European Peptide Symposium (37th EPS) & 14th International Peptide Symposium (14th IPS), Aug 2024, Florence, Italy. Wiley, Journal of Peptide Science, 30 (S2), pp.170-171, 2024
Poster de conférence
hal-04811378
v1
|
|
Differential release of miRNAs by visceral adipose tissue from obese patients with various metabolic status56th Annual Meeting of the European Association for the Study of Diabetes (EASD 2020), Sep 2020, Vienne, Austria. Springer, Diabetologia, 63 (suppl. 1), pp.527, 2020
Poster de conférence
hal-05056458
v1
|
|
Development of pharmacologically active microcarriers transporting stem cells and releasing growth factors integrated in a thermosensitive injectable hydrogel for an efficient tissue engineering strategyAnnual Meeting Tissue Engineering & Regenerative Medicine (TERMIS), 2011, Houston, United States. 2011
Poster de conférence
hal-03184060
v1
|
|
Systemic treatment of ferrocenyl-based drug loaded lipid nanocapsules on a subcutaneous 9L glioma model in rats7th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2010, Valletta, Malte. 2010
Poster de conférence
hal-03179509
v1
|
|
Exosomal melanotransferrin as a potential biomarker for metastatic melanoma2021
Pré-publication, Document de travail
hal-03101491
v1
|
Scaffolds for Controlled Release of Cartilage Growth FactorsScaffolds for Controlled Release of Cartilage Growth Factors, pp.171-180, 2015, ⟨10.1007/978-1-4939-2938-2_12⟩
Chapitre d'ouvrage
hal-03212213
v1
|
|
|
Near-infrared optical imaging of nucleic acid nanocarriers in vivo.Nanotechnology for Nucleic Acid Delivery, 948, Humana Press, pp.49-65, 2013, ⟨10.1007/978-1-62703-140-0_5⟩
Chapitre d'ouvrage
inserm-00874399
v1
|
|
Near-Infrared Optical Imaging of Nucleic Acid Nanocarriers In VivoNear-Infrared Optical Imaging of Nucleic Acid Nanocarriers In Vivo, pp.49-65, 2013, ⟨10.1007/978-1-62703-140-0_5⟩
Chapitre d'ouvrage
hal-03212203
v1
|
Microsphere compositions, preparation method and applications thereofFrance, Patent n° : Non spécifié. 2013
Brevet
hal-03180823
v1
|
|
Thérapie génique à l'aide de nanocapsules lipidiques PEGyléesSciences pharmaceutiques. Université d'Angers, 2009. Français. ⟨NNT : ⟩
Thèse
tel-00459201
v1
|