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A β‐Glucuronidase‐Responsive Albumin‐Binding Prodrug of a Potent Focal Adhesion Kinase Inhibitor for Targeted Cancer Therapy
Louna Mossino
,
Rémi Châtre
,
Mélanie Poinsot
,
Mathieu Rodero
,
Pierre Nioche
et al.
Article dans une revue
hal-05468185v1
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Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography
Nicolas Mathas
,
Emmanuelle Braud
,
Erwan Galardon
,
Lucie Larigot
,
Mélanie Etheve-Quelquejeu
et al.
Article dans une revue
hal-05343900v1
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Optimization of prodrug activation by enzymatic cleavage of the β‐lactam ring of carbapenems
Katie Burke
,
Quentin Herail
,
Ines Zerguine
,
Catherine Bougault
,
Michel Arthur
et al.
Article dans une revue
hal-05287283v1
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Synthesis of RNA conjugates as bisubstrates for the study of transferases
Laura Iannazzo
,
Emmanuelle Braud
,
Matthieu Fonvielle
,
Mélanie Etheve-Quelquejeu
Article dans une revue
hal-05287289v1
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A multiscale study to characterize SHAPE probe/ RNA molecules pre-reactive complex and its role in initiating the SHAPE reaction
Cécilia Hognon
,
Ameni Ben Abdeljaoued
,
Pierre Hardouin
,
Mélanie Etheve-Quelquejeu
,
Bruno Sargueil
et al.
Article dans une revue
hal-05226372v1
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Metal‐Catalyzed Cross‐Coupling for the Synthesis of β‐Lactam Drugs and Related Chemical Probes
Jules Bresson
,
Katie Burke
,
Mélanie Ethève‐quelquejeu
,
Laura Iannazzo
,
Kevin Cariou
Article dans une revue
hal-05287299v1
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Flexizyme‐Based Strategy for the Synthesis of Stable, Non‐Isomerizable Amide‐Linked 2’‐Aminoacyl‐tRNAs and their Shortened Analogs
Lia Maurin
,
Carine Tellier-Lebegue
,
Laura Iannazzo
,
Takayuki Katoh
,
Delphine Patin
et al.
Article dans une revue
hal-05468180v1
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Investigation of a squaramide motif as a bioisostere of the amino-acid group of S-adenosyl-L-methionine and its functional impact on RNA methylation
Jianxun Du
,
Batoul Mahcene
,
Valerii Martynov
,
Elisa Frezza
,
Christelle Vasnier
et al.
Article dans une revue
hal-05287286v2
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Synthetic approaches to bis-adenosine derivatives as potential bisubstrates of RNA methyltransferases
Jianxun Du
,
Bastien Felipe
,
Dylan Coelho
,
Laura Iannazzo
,
Alexandre David
et al.
Article dans une revue
hal-05139585v1
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Copper catalyzed cycloaddition for the synthesis of non isomerisable 2’ and 3’-regioisomers of arg-tRNAarg
Yusif Afandizada
,
Thilini Abeywansha
,
Vincent Guerineau
,
Yi Zhang
,
Bruno Sargueil
et al.
Article dans une revue
hal-05312525v1
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Halo‐1,2,3‐triazoles: Valuable Compounds to Access Biologically Relevant Molecules
Dylan Coelho
,
Yoann Colas
,
Mélanie Ethève-Quelquejeu
,
Emmanuelle Braud
,
Laura Iannazzo
Article dans une revue
hal-05312524v1
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Synthesis of Peptidyl-tRNA Mimics for Structural Biology Applications
Yury Polikanov
,
Mélanie Ethève-Quelquejeu
,
Ronald Micura
Article dans une revue
hal-05312531v1
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Synthesis of Bisubstrate Analogues for RNA Methylation Studies using two Transition‐Metal‐Catalyzed Reactions
Dylan Coelho
,
Laurent Le Corre
,
Karolina Bartosik
,
Laura Iannazzo
,
Emmanuelle Braud
et al.
Article dans une revue
hal-04246592v1
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The catalytic mechanism of the RNA methyltransferase METTL3
Ivan Corbeski
,
Pablo Andrés Vargas-Rosales
,
Rajiv Kumar Bedi
,
Jiahua Deng
,
Dylan Coelho
et al.
Article dans une revue
hal-05287291v1
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Ruthenium‐Catalyzed Cycloaddition for Introducing Chemical Diversity in Second‐Generation β‐Lactamase Inhibitors
Flavie Bouchet
,
Jean‐philippe Barnier
,
Ines Sayah
,
Youcef Bagdad
,
Maria Miteva
et al.
Article dans une revue
hal-05312533v1
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PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase
Leeroy Baron
,
Justine Hadjerci
,
Leishemba Thoidingjam
,
Marina Plays
,
Romain Bucci
et al.
Article dans une revue
hal-04092530v1
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Traceless Staudinger Ligation to Access Stable Aminoacyl- or Peptidyl-Dinucleotide
Camélia Kitoun
,
Saidbakhrom Saidjalolov
,
Delphine Bouquet
,
Fabiola Djago
,
Quentin Blancart-Remaury
et al.
Article dans une revue
hal-04294940v1
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Enzymatic synthesis of vancomycin-modified DNA
Chiara Figazzolo
,
Frédéric Bonhomme
,
Saidbakhrom Saidjalolov
,
Mélanie Ethève-Quelquejeu
,
Marcel Hollenstein
Article dans une revue
hal-03927068v1
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Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis
Lauriane Rietmeyer
,
Inès Li de la Sierra-Gallay
,
Guy Schepers
,
Delphine Dorchêne
,
Laura Iannazzo
et al.
Article dans une revue
hal-03879768v1
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Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis
Jean-Philippe Barnier
,
Saidbakhrom Saidjalolov
,
Flavie Bouchet
,
Louis Mayer
,
Zainab Edoo
et al.
Article dans une revue
hal-05312535v1
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|
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Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase
Vincent Meynier
,
Laura Iannazzo
,
Marjorie Catala
,
Stephanie Oerum
,
Emmanuelle Braud
et al.
Article dans une revue
hal-03689976v1
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|
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Click and Release Chemistry for Activity-Based Purification of β-Lactam Targets
Saidbakhrom Saidjalolov
,
Emmanuelle Braud
,
Zainab Edoo
,
Laura Iannazzo
,
Filippo Rusconi
et al.
Article dans une revue
hal-03281379v1
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|
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Traceless Staudinger Ligation for Bioconjugation of RNA
Camélia Kitoun
,
Matthieu Fonvielle
,
Michel Arthur
,
Mélanie Etheve‐quelquejeu
,
Laura Iannazzo
Article dans une revue
hal-03647120v1
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|
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Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus
Lauriane Rietmeyer
,
Nicolas Fix-Boulier
,
Chloé Le Fournis
,
Laura Iannazzo
,
Camelia Kitoun
et al.
Article dans une revue
hal-03201622v1
|
|
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Traceless Staudinger Ligation To Introduce Chemical Diversity on β-Lactamase Inhibitors of Second Generation
Flavie Bouchet
,
Heiner Atze
,
Michel Arthur
,
Mélanie Ethève-Quelquejeu
,
Laura Iannazzo
Article dans une revue
hal-03647098v1
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|
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Synthesis of carbapenems containing peptidoglycanmimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity
Saidbakhrom Saidjalolov
,
Zainab Edoo
,
Matthieu Fonvielle
,
Louis Mayer
,
Laura Iannazzo
et al.
Article dans une revue
hal-03184204v1
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|
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Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma
Bo Li
,
Yongliang Li
,
Céline Tomkiewicz-Raulet
,
Pascal Dao
,
Daniel Lietha
et al.
Article dans une revue
hal-05437532v1
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The neurobehavioral effects of the designer drug naphyrone – an experimental investigation with pharmacokinetics and concentration/effect relationship in mice
Bruno Mégarbane
,
Camille Gamblin
,
Olivier Roussel
,
Elodie Bouaziz-Amar
,
Lucie Chevillard
et al.
Article dans une revue
hal-03823023v1
|
|
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Diazabicyclooctane Functionalization for Inhibition of β-Lactamases from Enterobacteria
Flavie Bouchet
,
Heiner Atze
,
Matthieu Fonvielle
,
Zainab Edoo
,
Michel Arthur
et al.
Article dans une revue
hal-03646829v2
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|
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Microwave-assisted synthesis of 2,5-disubstituted pyrimidine derivatives via Buchwald-Hartwig amination
Bo Li
,
Mélanie Etheve-Quelquejeu
,
Expédite Yen-Pon
,
Christiane Garbay
,
Huixiong Chen
Article dans une revue
hal-03488531v1
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|
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Design and synthesis of a peptide derivative of ametantrone targeting the major groove of the d(GGCGCC) 2 palindromic sequence
Alberto Ongaro
,
Giovanni Ribaudo
,
Emmanuelle Braud
,
Mélanie Ethève-Quelquejeu
,
Michele de Franco
et al.
Article dans une revue
hal-03689989v1
|
|
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Phosphine-Mediated Bioconjugation of the 3′-End of RNA
Camelia Kitoun
,
Matthieu Fonvielle
,
Nicolas Sakkas
,
Manon Lefresne
,
Fabiola Djago
et al.
Article dans une revue
hal-02996863v1
|
|
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Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles
Yun Luo
,
Yu Xiao
,
Delphine Onidas
,
Laura Iannazzo
,
Mélanie Ethève-Quelquejeu
et al.
Article dans une revue
hal-03411993v1
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|
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Synthesis of triazole-linked SAM-adenosine 2 conjugates: functionalization of adenosine at N-1 or N-6 position without protecting groups
Colette Atdjian
,
Dylan Coelho
,
Laura Iannazzo
,
Mélanie Etheve-Quelquejeu
,
Emmanuelle Braud
Article dans une revue
hal-02915430v1
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|
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Bisubstrate analogues as structural tools to investigate m 6 A methyltransferase active sites
Stephanie Oerum
,
Marjorie Catala
,
Colette Atdjian
,
Franck Brachet
,
Luc Ponchon
et al.
Article dans une revue
hal-02353503v1
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|
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Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat
Luisa Alessandra Atehortua-Martinez
,
Cyriaque Masniere
,
Patrizia Campolongo
,
Stéphanie Chasseigneaux
,
Jacques Callebert
et al.
Article dans une revue
hal-03908457v1
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|
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Is the 3,4-methylendioxypyrovalerone/mephedrone combination responsible for enhanced stimulant effects? A rat study with investigation of the effect/concentration relationships
Nadia Benturquia
,
Lucie Chevillard
,
Christophe Poiré
,
Olivier Roussel
,
Camille Cohier
et al.
Article dans une revue
hal-03860105v1
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|
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Is the 3,4-methylendioxypyrovalerone/mephedrone combination responsible for enhanced stimulant effects? A rat study with investigation of the effect/concentration relationships
Nadia Benturquia
,
Lucie Chevillard
,
Christophe Poiré
,
Olivier Roussel
,
Camille Cohier
et al.
Article dans une revue
hal-03823031v1
|
|
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Negative impact of carbapenem methylation on the reactivity of β-lactams for cysteine acylation revealed by quantum calculations and kinetic analyses
Nicholus Bhattacharjee
,
Sébastien Triboulet
,
Vincent Dubée
,
Matthieu Fonvielle
,
Zainab Edoo
et al.
Article dans une revue
hal-02057268v1
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|
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Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat
Luisa Alessandra Atehortua-Martinez
,
Cyriaque Masniere
,
Patrizia Campolongo
,
Stéphanie Chasseigneaux
,
Jacques Callebert
et al.
Article dans une revue
hal-02557840v1
|
|
|
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat
Luisa Alessandra Atehortua-Martinez
,
Cyriaque Masniere
,
Patrizia Campolongo
,
Stéphanie Chasseigneaux
,
Jacques Callebert
et al.
Article dans une revue
hal-03860016v1
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|
|
Synthesis of Avibactam Derivatives and Activity on β-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria
Zainab Edoo
,
Laura Iannazzo
,
Fabrice Compain
,
Inès Li de La Sierra Gallay
,
Herman Van Tilbeurgh
et al.
Article dans une revue
hal-02177911v1
|
|
|
Is the 3,4-methylendioxypyrovalerone/mephedrone combination responsible for enhanced stimulant effects? A rat study with investigation of the effect/concentration relationships
Nadia Benturquia
,
Lucie Chevillard
,
Christophe Poiré
,
Olivier Roussel
,
Camille Cohier
et al.
Article dans une revue
hal-01899917v1
|
|
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Synthesis of SAM-Adenosine Conjugates for the Study of m 6 A-RNA Methyltransferases
Colette Atdjian
,
Laura Iannazzo
,
Emmanuelle Braud
,
Mélanie Ethève-Quelquejeu
Article dans une revue
hal-03647207v1
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|
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Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes
Laura Iannazzo
,
Matthieu Fonvielle
,
Emmanuelle Braud
,
Hubert Hřebabecký
,
Eliška Procházková
et al.
Article dans une revue
hal-03689994v1
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|
|
Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d -Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis
Flora Ngadjeua
,
Emmanuelle Braud
,
Saidbakhrom Saidjalolov
,
Laura Iannazzo
,
Dirk Schnappinger
et al.
Article dans une revue
hal-01817697v1
|
|
|
Synthesis of SAM-Adenosine Conjugates for the Study of m 6 A-RNA Methyltransferases
Colette Atdjian
,
Laura Iannazzo
,
Emmanuelle Braud
,
Mélanie Ethève-Quelquejeu
Article dans une revue
hal-03689993v1
|
|
|
Structure-Based Design, Synthesis, and Characterization of the First Irreversible Inhibitor of Focal Adhesion Kinase
Expédite Yen-Pon
,
Bo Li
,
Marta Acebrón-Garcia-De-Eulate
,
Céline Tomkiewicz-Raulet
,
John Dawson
et al.
Article dans une revue
hal-02196326v1
|
|
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Synthesis of lipid-carbohydrate-peptidyl-RNA conjugates to explore the limits imposed by the substrate specificity of cell wall enzymes on the acquisition of drug resistance
Matthieu Fonvielle
,
Ahmed Bouhss
,
Coralie Hoareau
,
Delphine Patin
,
Dominique Mengin-Lecreulx
et al.
Article dans une revue
hal-01962025v1
|
|
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Synthesis of SAM-Adenosine Conjugates for the Study of m 6 A-RNA Methyltransferases
Colette Atdjian
,
Laura Iannazzo
,
Emmanuelle Braud
,
Mélanie Ethève-Quelquejeu
Article dans une revue
hal-02353523v1
|
|
|
Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d -Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis
Flora Ngadjeua
,
Emmanuelle Braud
,
Saidbakhrom Saidjalolov
,
Laura Iannazzo
,
Dirk Schnappinger
et al.
Article dans une revue
hal-03647180v1
|
|
|
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
Manal Sarkis
,
Maria Miteva
,
Maria Chiara Dasso Lang
,
Maryse Jaouen
,
Marie-Agnès Sari
et al.
Article dans une revue
hal-03684762v1
|
|
|
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
Manal Sarkis
,
Maria Miteva
,
Maria Chiara Dasso Lang
,
Maryse Jaouen
,
Marie-Agnès Sari
et al.
Article dans une revue
hal-03689998v1
|
|
|
Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.
Matthieu Fonvielle
,
Nicolas Sakkas
,
Laura Iannazzo
,
Chloé Le fournis
,
Delphine Patin
et al.
Article dans une revue
istex
hal-01440830v1
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|
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Monitoring of reversible boronic acid–diol interactions by fluorine NMR spectroscopy in aqueous media
Laura Iannazzo
,
Erica Benedetti
,
Marjorie Catala
,
Mélanie Etheve-Quelquejeu
,
Carine Tisné
et al.
Article dans une revue
hal-03544508v1
|
|
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Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics
Eric Leclerc
,
Xavier Pannecoucke
,
Mélanie Etheve-Quelquejeu
,
M. Sollogoub
Article dans une revue
hal-00825637v1
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|
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Kinetic features of L,D-transpeptidase inactivation critical for β-lactam antibacterial activity.
Sébastien Triboulet
,
Vincent Dubée
,
Lauriane Lecoq
,
Catherine M Bougault
,
Jean-Luc Mainardi
et al.
Article dans une revue
hal-01321589v1
|
|
|
Crystal structure of a chiral binaphthyl porphyrin
Eric Rose
,
Nicolas Raoul
,
Mélanie Etheve-Quelquejeu
,
Emma Gallo
,
Bernard Boitrel
et al.
Article dans une revue
hal-00863134v1
|
|
|
Idiosyncratic features in tRNAs participating in bacterial cell wall synthesis
Régis Villet
,
Matthieu Fonvielle
,
Patricia Busca
,
Maryline Chemama
,
Antoine P. Maillard
et al.
Article dans une revue
hal-02331010v1
|