MR

Michael Rera

95 %
Libre accès
43
Documents
Affiliations actuelles
  • Université Paris Cité (UPCité)
  • Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A-IBPS)
  • Unité de Biologie Fonctionnelle et Adaptative (BFA (UMR_8251 / U1133))
  • Institut des sciences biologiques - CNRS Biologie (INSB-CNRS)
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Publications

Publications

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ProteoCast: a web server to predict, validate, and interpret missense variant effects

Marina Abakarova , Maria Inés Freiberger , Arnaud Liehrmann , Michael Rera , Elodie Laine

Journal of Molecular Biology, 2026, pp.169657. ⟨10.1016/j.jmb.2026.169657⟩

Article dans une revue hal-05350695v2
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Two-phase model of ageing in mice for improved identification of age-related and late life metabolic decline

Céline Cansell , Vivien Goepp , Fanny Bain , Nicolas Todd , Veronique Douard et al.

BMC Biology, 2025, 23 (1), pp.318. ⟨10.1186/s12915-025-02421-6⟩

Article dans une revue hal-05334950v1
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Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource

Joaquin C. B. Nunez , Marta Coronado-Zamora , Mathieu Gautier , Martin Kapun , Sonja Steindl et al.

Molecular Biology and Evolution, 2025, 42 (8), pp.msaf132. ⟨10.1101/2024.11.10.622744⟩

Article dans une revue hal-04779897v2
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Telomerase Depletion Accelerates Ageing of the Zebrafish Brain

Raquel Martins , Savandara Besse , Pam Ellis , Rabia Sevil , Naomi Hartopp et al.

Aging Cell, 2025, ⟨10.1111/acel.70280⟩

Article dans une revue hal-05335533v1
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Ageing as a Two-Phase Process: Development of a new Theoretical Framework

Nicolas Todd , Flaminia Zane , Claire Macmurray , Clémence Guillermain , Céline Cansell et al.

Frontiers in Aging Neuroscience, 2024, 5, ⟨10.3389/fragi.2024.1378351⟩

Article dans une revue hal-04423745v1

A scenario for an evolutionary selection of ageing

T. Roget , C. Macmurray , P. Jolivet , S. Méléard , Michael Rera Article dans une revue hal-04385137v1
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Alignment-based protein mutational landscape prediction: doing more with less

Marina Abakarova , Céline Marquet , Michael Rera , Burkhard Rost , Elodie Laine

Genome Biology and Evolution, 2023, 15 (11), pp.evad201. ⟨10.1093/gbe/evad201⟩

Article dans une revue hal-03907222v4
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Drosophilids with darker cuticle have higher body temperature under light

Laurent Freoa , Luis-Miguel Chevin , Philippe Christol , Sylvie Méléard , Michael Rera et al.

Scientific Reports, 2023, 13 (1), pp.3513. ⟨10.1038/s41598-023-30652-6⟩

Article dans une revue hal-04014031v1

Intestinal barrier dysfunction: an evolutionarily conserved hallmark of aging

Anna Salazar , Ricardo Aparicio , Rebecca Clark , Michael Rera , David Walker

Disease Models & Mechanisms, 2023, 16 (4), ⟨10.1242/dmm.049969⟩

Article dans une revue hal-04183515v1
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Smurfness‐based two‐phase model of ageing helps deconvolve the ageing transcriptional signature

Flaminia Zane , Hayet Bouzid , Sofia Sosa Marmol , Mira Brazane , Savandara Besse et al.

Aging Cell, 2023, 22 (11), pp.e13946. ⟨10.1111/acel.13946⟩

Article dans une revue hal-04244337v1

Empowering grassroots innovation to accelerate biomedical research

Bastian Greshake Tzovaras , Michael Rera , Edwin Wintermute , Katharina Kloppenborg , Juliette Ferry-Danini et al.

PLoS Biology, 2021

Article dans une revue hal-04183524v1
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Empowering grassroots innovation to accelerate biomedical research

Bastian Greshake Tzovaras , Michael Rera , Edwin Wintermute , Katharina Kloppenborg , Juliette Ferry-Danini et al.

PLoS Biology, 2021, 19 (8), pp.e3001349. ⟨10.1371/journal.pbio.3001349⟩

Article dans une revue hal-03365793v1

Empowering grassroots innovation to accelerate biomedical research

Bastian Greshake Tzovaras , Michael Rera , Edwin Wintermute , Katharina Kloppenborg , Juliette Ferry-Danini et al.

PLoS Biology, 2021, 19 (8), pp.e3001349. ⟨10.1371/journal.pbio.3001349⟩

Article dans une revue hal-03798677v1
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Conséquences éthiques et sociales de biomarqueurs prédictifs de la mort chez l’homme

Marie Gaille , Marco Araneda , Clément Dubost , Clémence Guillermain , Sarah Kaakai et al.

Médecine/Sciences, 2020, 36 (12), pp.1199-1206. ⟨10.1051/medsci/2020228⟩

Article dans une revue hal-03049539v1
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Ethical and social implications of approaching death prediction in humans - when the biology of ageing meets existential issues

Marie Gaille , Marco Araneda , Clément Dubost , Clémence Guillermain , Sarah Kaakai et al.

BMC Medical Ethics, 2020, 21 (1), ⟨10.1186/s12910-020-00502-5⟩

Article dans une revue halshs-03085823v2
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A birth–death model of ageing: from individual-based dynamics to evolutive differential inclusions

Sylvie Méléard , Michael Rera , Tristan Roget

Journal of Mathematical Biology, 2019, 79 (3), pp.901-939. ⟨10.1007/s00285-019-01382-z⟩

Article dans une revue hal-02347631v1

A birth–death model of ageing: from individual-based dynamics to evolutive differential inclusions

Sylvie Méléard , Michael Rera , Tristan Roget

Journal of Mathematical Biology, 2019, 79 (3), pp.901-939. ⟨10.1007/s00285-019-01382-z⟩

Article dans une revue hal-03365814v1
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Identification of cardioprotective drugs by medium-scale in vivo pharmacological screening on a Drosophila cardiac model of Friedreich's ataxia

Amandine Palandri , Elodie Martin , Maria Russi , Michael Rera , Hérvé Tricoire et al.

Disease Models & Mechanisms, 2018, 11 (7), pp.dmm033811. ⟨10.1242/dmm.033811⟩

Article dans une revue hal-02348060v1

How to Catch a Smurf? – Ageing and Beyond…In vivo Assessment of Intestinal Permeability in Multiple Model Organisms

Raquel Martins , Andrew Mccracken , Mirre Simons , Catarina Henriques , Michael Rera

Bio-protocol , 2018, 8 (3), ⟨10.21769/BioProtoc.2722⟩

Article dans une revue hal-04183528v1
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The Smurf transition: new insights on ageing from end-of-life studies in animal models

Michael Rera , Céline Vallot , Christel Lefrançois

Current Opinion in Oncology, 2018, 30 (1), pp.38-44. ⟨10.1097/cco.0000000000000419⟩

Article dans une revue hal-01981182v1
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How to Catch a Smurf? – Ageing and Beyond…In vivo Assessment of Intestinal Permeability in Multiple Model Organisms

Raquel Martins , Andrew John Mccracken , Mirre Simons , Catarina Henriques , Michael Rera

Bio-protocol , 2018, 8 (3), ⟨10.21769/BioProtoc.2722⟩

Article dans une revue hal-02347578v1
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Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster

Anil Rana , Matheus Oliveira , Andy Khamoui , Ricardo Aparicio , Michael Rera et al.

Nature Communications, 2017, 8, pp.448. ⟨10.1038/s41467-017-00525-4⟩

Article dans une revue hal-02347415v1

Two phases of aging separated by the Smurf transition as a public path to death

Emilie Dambroise , L.éa Monnier , L.u Ruisheng , Hugo Aguilaniu , Jean-Stéphane Joly et al.

Scientific Reports, 2016, 6 (1), pp.23523. ⟨10.1038/srep23523⟩

Article dans une revue hal-03798908v1
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Two phases of aging separated by the Smurf transition as a public path to death.

Emilie Dambroise , Léa Monnier , Lu Ruisheng , Hugo Aguilaniu , Jean-Stéphane Joly et al.

Scientific Reports, 2016, 6, pp.23523. ⟨10.1038/srep23523⟩

Article dans une revue hal-01304283v1

A New, Discontinuous 2 Phases of Aging Model: Lessons from Drosophila melanogaster

Hervé Tricoire , Michael Rera

PLoS ONE, 2015, 10 (11), pp.e0141920. ⟨10.1371/journal.pone.0141920⟩

Article dans une revue hal-03798914v1

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

Rebecca i. Clark , Anna Salazar , Ryuichi Yamada , Sorel Fitz-Gibbon , Marco Morselli et al.

Cell Reports, 2015, 12 (10), pp.1656-1667. ⟨10.1016/j.celrep.2015.08.004⟩

Article dans une revue hal-02347371v1

A Yeast/Drosophila Screen to Identify New Compounds Overcoming Frataxin Deficiency

Alexandra Seguin , Véronique Monnier , Amandine Palandri , Frédéric Bihel , Michael Rera et al.

Oxidative Medicine and Cellular Longevity, 2015, 2015, pp.565140. ⟨10.1155/2015/565140⟩

Article dans une revue hal-01267591v1
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A New, Discontinuous 2 Phases of Aging Model: Lessons from Drosophila melanogaster

Hérvé Tricoire , Michael Rera

PLoS ONE, 2015, 10 (11), pp.e0141920. ⟨10.1371/journal.pone.0141920⟩

Article dans une revue hal-02347534v1
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AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner

Matthew Ulgherait , Anil Rana , Michael Rera , Jacqueline Graniel , David w. Walker

Cell Reports, 2014, 8 (6), pp.1767-1780. ⟨10.1016/j.celrep.2014.08.006⟩

Article dans une revue hal-02347387v1

Increased longevity mediated by yeast NDI1 expression in <i>Drosophila</i> intestinal stem and progenitor cells

Jae Hur , Sepehr Bahadorani , Jacqueline Graniel , Christopher Koehler , Matthew Ulgherait et al.

Aging, 2013, 5 (9), pp.662-681. ⟨10.18632/aging.100595⟩

Article dans une revue hal-02347504v1

Organ-specific mediation of lifespan extension: More than a gut feeling?

Michael Rera , Masoud Azizi , David Walker

Ageing Research Reviews - ARR, 2013, 12 (1), pp.436-444. ⟨10.1016/j.arr.2012.05.003⟩

Article dans une revue hal-02347402v1

Why do old flies die?

Michael Rera , Rebecca Clark , David Walker

Aging, 2013, 5 (8), pp.586-587. ⟨10.18632/aging.100589⟩

Article dans une revue hal-02347598v1

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

Michael Rera , Sepehr Bahadorani , Jaehyoung Cho , Christopher l. Koehler , Matthew Ulgherait et al.

Cell Metabolism, 2011, 14 (5), pp.623-634. ⟨10.1016/j.cmet.2011.09.013⟩

Article dans une revue hal-02347344v1

Mitochondrial electron transport chain dysfunction during development does not extend lifespan in Drosophila melanogaster

Michael Rera , Véronique Monnier , Hérvé Tricoire

Mechanisms of Ageing and Development, 2010, 131 (2), pp.156-164. ⟨10.1016/j.mad.2010.01.004⟩

Article dans une revue istex hal-02347522v1
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On intestinal barrier dysfunction as a conserved late-life state in ageing

Michael Rera

2026

Pré-publication, Document de travail hal-05535422v1
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Proteome-wide Prediction of the Functional Impact of Missense Variants with ProteoCast

Marina Abakarova , Maria Ines Freiberger , Arnaud Liehrmann , Michael Rera , Elodie Laine

2025

Pré-publication, Document de travail hal-05334897v1
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Smurf Mice": revolutionising our understanding of age-related and end-of-life animal physiology

Céline Cansell , Vivien Goepp , Fanny Bain , Nicolas Todd , Veronique Douard et al.

2025

Pré-publication, Document de travail hal-05355448v1
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Two phases model of ageing in mice: towards a better identification of age-related and late-life metabolic decline [Registered Report Stage 1 Protocol]

Céline Cansell , Vivien Goepp , Fanny Bain , Nicolas Todd , Véronique Douard et al.

2023

Pré-publication, Document de travail hal-04234744v1
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TRANSCRIPTOMIC SIGNATURES OF TELOMERASE-DEPENDENT AND -INDEPENDENT AGEING, IN THE ZEBRAFISH GUT AND BRAIN

Raquel Martins , Michael Rera , Catarina Henriques

2023

Pré-publication, Document de travail hal-04183519v1

TRANSCRIPTOMIC SIGNATURES OF TELOMERASE-DEPENDENT AND -INDEPENDENT AGEING, IN THE ZEBRAFISH GUT AND BRAIN

Raquel Martins , Michael Rera , Catarina Henriques

2022

Pré-publication, Document de travail hal-03798695v1
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Positive selection of senescence through increased evolvability: ageing is not a by-product of evolution

Tristan Roget , Pierre Jolivet , Sylvie Méléard , Michael Rera

2022

Pré-publication, Document de travail hal-03798671v1
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A scenario for an evolutionary selection of ageing

T. Roget , Claire Macmurray , P. Jolivet , S. Méléard , Michael Rera

2023

Pré-publication, Document de travail hal-04183523v1
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Modernisation de la publication scientifique

Nicolas Eberlé , Michael Rera , Raphaël Aupee

2018

Pré-publication, Document de travail hal-01692668v3