Mirko Minini

Research Scientist at NABI (Nanomédecine, Biologie Extracellulaire, Intégratome et Innovations en Santé), Paris (FR)
33%
Libre accès
15
Documents
Affiliations actuelles
  • NAnomédecine, Biologie extracellulaire, Intégratome et Innovations (NABI (UMR 8175 / U1334))
  • Centre de Recherche Saint-Antoine (CRSA)
  • Institut National de la Santé et de la Recherche Médicale (INSERM)
  • Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy
  • Department of Surgery “P. Valdoni”, University of Rome “Sapienza”, Rome, Italy.
Identifiants chercheurs
Contact

Présentation

As a cancer scientist, I’m passionate about understanding the intricate crosstalk among CAFs, ECM, and immune cells, as a driver of therapy resistance. By using cutting-edge approaches and developing advanced animal-free models, I aim to uncover the complexities of tumor biology. My work is fueled by curiosity, a drive for impactful discoveries, and a belief that collaboration is the key to unlocking breakthroughs in science

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Tumor-Immune Microenvironment Profiling HTS assays Primary cell culture Organoids Multi-Omics Data Analysis CRISPR/Cas9 Multi-Color Flow Cytometry ELISA Assay Drug Screening T-cell Functional Assays

Publications

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Publications

Laser-activated nanoparticles rewire tumor microenvironment enhancing PD-1 blockade and T cell response in cholangiocarcinoma

Mirko Minini , Giulio Avveduto , Sonia Becharef , Marie Meunier-Thaens , Bouchra Lekbaby et al.
Article dans une revue hal-05411190 v1

Loss of Aquaporin-1 in Tumor Cells Fosters Intrahepatic Cholangiocarcinoma Progression

César Gaspari , Carine Beaupere , Seth Richard , Estanislao Peixoto , Bouchra Lekbaby et al.
American Journal of Pathology, 2025, ⟨10.1016/j.ajpath.2025.10.007⟩
Article dans une revue hal-05411191 v1
Image document

Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions

Juliette Tokgozoglu , Valeria Pistorio , Mirko Minini , Pierre-Antoine Soret , Virginie Steunou et al.
Cell Death and Disease, 2025, 16 (1), pp.683. ⟨10.1038/s41419-025-08004-1⟩
Article dans une revue hal-05355442 v1
Image document

Crosstalk between cancer cell plasticity and immune microenvironment in cholangiocarcinoma

Mirko Minini , Allan Pavy , Bouchra Lekbaby , Laura Fouassier
Hepatoma Research, 2024, 2024 (10), ⟨10.20517/2394-5079.2023.69⟩
Article dans une revue (article de synthèse) hal-05430162 v1
Image document

Cancer-Associated Fibroblasts and Extracellular Matrix: Therapeutical Strategies for Modulating the Cholangiocarcinoma Microenvironment

Mirko Minini , Laura Fouassier
Current Oncology, 2023, 30 (4), pp.4185-4196. ⟨10.3390/curroncol30040319⟩
Article dans une revue (article de synthèse) hal-05430128 v1

miR-125a-5p impairs the metastatic potential in breast cancer via IP6K1 targeting

Mirko Minini , Alice Senni , Xingkang He , Sara Proietti , Domenico Liguoro et al.
Cancer Letters, 2021, 520, pp.48-56. ⟨10.1016/j.canlet.2021.07.001⟩
Article dans une revue (data paper) hal-05430198 v1

Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis

Nicolò Pernigoni , Elena Zagato , Arianna Calcinotto , Martina Troiani , Ricardo Pereira Mestre et al.
Science, 2021, 374 (6564), pp.216-224. ⟨10.1126/science.abf8403⟩
Article dans une revue (data paper) hal-05430154 v1

Increase in motility and invasiveness of MCF 7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation

Sara Proietti , Angela Catizone , Maria Grazia Masiello , Simona Dinicola , Gianmarco Fabrizi et al.
Journal of Pineal Research, 2018, 64 (4), ⟨10.1111/jpi.12467⟩
Article dans une revue (data paper) hal-05430171 v1

Inositol induces mesenchymal-epithelial reversion in breast cancer cells through cytoskeleton rearrangement

Simona Dinicola , Gianmarco Fabrizi , Maria Grazia Masiello , Sara Proietti , Alessandro Palombo et al.
Experimental Cell Research, 2016, 345 (1), pp.37-50. ⟨10.1016/j.yexcr.2016.05.007⟩
Article dans une revue (data paper) istex hal-05430179 v1

39P Analysis of the immune response patterns in localized prostate cancer

S. Merler , B. Calì , S. Zumerle , D. Braga , V. Moscarda et al.
ESMO - Immuno-Oncology and Technology, Dec 2024, Geneve, Suisse, Switzerland. pp.100921, ⟨10.1016/j.iotech.2024.100921⟩
Communication dans un congrès hal-05430124 v1

Deciphering the direct and indirect antitumoral effects of cold atmospheric plasma - application to the cholangiocarcinoma

Allan Pavy , Henri Decauchy , Bouchra Lekbaby , Manon Soulier , Mirko Minini et al.
International Workshop on Plasma Cancer (IWPCT 8), Mar 2023, Raleigh, United States
Communication dans un congrès hal-04397200 v1

Unravelling the multifaceted antitumor effects of cold atmospheric pasma on cholangiocarcinoma

Allan Pavy , Henri Decauchy , Bouchra Lekbaby , Manon Soulier , Mirko Minini et al.
2nd annual meeting of COST PlasTher, Sep 2023, Bologna, Italy
Communication dans un congrès hal-04397245 v1

Experimental Model of Biliary Tract Cancers: Subcutaneous Xenograft of Human Cell Lines in Immunodeficient Nude Mice

Bouchra Lekbaby , Javier Vaquero , Allan Pavy , Mirko Minini , Ester Gonzalez-Sanchez et al.
Liver Carcinogenesis, 2769, Springer US, pp.87-98, 2024, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3694-7_7⟩
Chapitre d'ouvrage hal-05430246 v1

Revisiting the Concept of Human Disease

Mariano Bizzarri , Mirko Minini , Noemi Monti
Approaching Complex Diseases, 2, Springer International Publishing, pp.1-34, 2020, Human Perspectives in Health Sciences and Technology, ⟨10.1007/978-3-030-32857-3_1⟩
Chapitre d'ouvrage hal-05430248 v1