Mirko Minini

Research Scientist at NABI (Nanomédecine, Biologie Extracellulaire, Intégratome et Innovations en Santé), Paris (FR)
48 %
Libre accès
21
Documents
Affiliations actuelles
  • NAnomédecine, Biologie extracellulaire, Intégratome et Innovations (NABI (UMR 8175 / U1334))
  • Centre de Recherche Saint-Antoine (CRSA)
  • Institut National de la Santé et de la Recherche Médicale (INSERM)
  • Department of Experimental Medicine, Sapienza University of Rome, 00161, Rome, Italy
  • Department of Surgery “P. Valdoni”, University of Rome “Sapienza”, Rome, Italy.
Identifiants chercheurs
Contact

Présentation

As a cancer scientist, I’m passionate about understanding the intricate crosstalk among CAFs, ECM, and immune cells, as a driver of therapy resistance. By using cutting-edge approaches and developing advanced animal-free models, I aim to uncover the complexities of tumor biology. My work is fueled by curiosity, a drive for impactful discoveries, and a belief that collaboration is the key to unlocking breakthroughs in science

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Tumor-Immune Microenvironment Profiling HTS assays Primary cell culture Organoids Multi-Omics Data Analysis CRISPR/Cas9 Multi-Color Flow Cytometry ELISA Assay Drug Screening T-cell Functional Assays

Publications

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Publications

Loss of Aquaporin-1 in Tumor Cells Fosters Intrahepatic Cholangiocarcinoma Progression

César Gaspari , Carine Beaupere , Seth Richard , Estanislao Peixoto , Bouchra Lekbaby et al.

American Journal of Pathology, 2026, 196 (2), pp.428-444. ⟨10.1016/j.ajpath.2025.10.007⟩

Article dans une revue hal-05411191v1

Laser-activated nanoparticles rewire tumor microenvironment enhancing PD-1 blockade and T cell response in cholangiocarcinoma

Mirko Minini , Giulio Avveduto , Sonia Becharef , Marie Meunier-Thaens , Bouchra Lekbaby et al. Article dans une revue hal-05411190v1
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Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions

Juliette Tokgozoglu , Valeria Pistorio , Mirko Minini , Pierre-Antoine Soret , Virginie Steunou et al.

Cell Death and Disease, 2025, 16 (1), pp.683. ⟨10.1038/s41419-025-08004-1⟩

Article dans une revue hal-05355442v1
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Crosstalk between cancer cell plasticity and immune microenvironment in cholangiocarcinoma

Mirko Minini , Allan Pavy , Bouchra Lekbaby , Laura Fouassier

Hepatoma Research, 2024, 2024 (10), ⟨10.20517/2394-5079.2023.69⟩

Article dans une revue (article de synthèse) hal-05430162v1
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Cancer-Associated Fibroblasts and Extracellular Matrix: Therapeutical Strategies for Modulating the Cholangiocarcinoma Microenvironment

Mirko Minini , Laura Fouassier

Current Oncology, 2023, 30 (4), pp.4185-4196. ⟨10.3390/curroncol30040319⟩

Article dans une revue (article de synthèse) hal-05430128v1

miR-125a-5p impairs the metastatic potential in breast cancer via IP6K1 targeting

Mirko Minini , Alice Senni , Xingkang He , Sara Proietti , Domenico Liguoro et al.

Cancer Letters, 2021, 520, pp.48-56. ⟨10.1016/j.canlet.2021.07.001⟩

Article dans une revue (data paper) hal-05430198v1

Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis

Nicolò Pernigoni , Elena Zagato , Arianna Calcinotto , Martina Troiani , Ricardo Pereira Mestre et al.

Science, 2021, 374 (6564), pp.216-224. ⟨10.1126/science.abf8403⟩

Article dans une revue (data paper) hal-05430154v1
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Redifferentiation therapeutic strategies in cancer

Mariano Bizzarri , Alessandro Giuliani , Alessandra Cucina , Mirko Minini

Drug Discovery Today, 2020, 25, pp.731 - 738. ⟨10.1016/j.drudis.2020.01.021⟩

Article dans une revue (article de synthèse) hal-05430213v1

Constraints Shape Cell Function and Morphology by Canalizing the Developmental Path along the Waddington's Landscape

Mariano Bizzarri , Alessandro Giuliani , Mirko Minini , Noemi Monti , Alessandra Cucina

BioEssays, 2020, 42 (4), ⟨10.1002/bies.201900108⟩

Article dans une revue hal-05430159v1

Increase in motility and invasiveness of MCF 7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation

Sara Proietti , Angela Catizone , Maria Grazia Masiello , Simona Dinicola , Gianmarco Fabrizi et al.

Journal of Pineal Research, 2018, 64 (4), ⟨10.1111/jpi.12467⟩

Article dans une revue (data paper) hal-05430171v1
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From Implantation to Birth: Insight into Molecular Melatonin Functions

Gianfranco Carlomagno , Mirko Minini , Marco Tilotta , Vittorio Unfer

International Journal of Molecular Sciences, 2018, 19 (9), pp.2802. ⟨10.3390/ijms19092802⟩

Article dans une revue (article de synthèse) hal-05430164v1
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Reduced Burden of Chemotherapy Side-Effects in Patients Receiving Inositol Hexakisphosphate Alone or In Association with Myo-Inositol

Roberto Verna , Alessandro Giuliani , Virginia Todde , Mirko Minini , Vittorio Unfer

Cancer Studies and Therapeutics, 2017, ⟨10.31038/CST.2018311⟩

Article dans une revue (data paper) hal-05430228v1
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Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders

Simona Dinicola , Mirko Minini , Vittorio Unfer , Roberto Verna , Alessandra Cucina et al.

International Journal of Molecular Sciences, 2017, 18 (10), pp.2187. ⟨10.3390/ijms18102187⟩

Article dans une revue (article de synthèse) hal-05430205v1
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Melatonin, mitochondria, and the cancer cell

Sara Proietti , Alessandra Cucina , Mirko Minini , Mariano Bizzarri

Cellular and Molecular Life Sciences, 2017, 74 (21), pp.4015 - 4025. ⟨10.1007/s00018-017-2612-z⟩

Article dans une revue (article de synthèse) hal-05430189v1

Inositol induces mesenchymal-epithelial reversion in breast cancer cells through cytoskeleton rearrangement

Simona Dinicola , Gianmarco Fabrizi , Maria Grazia Masiello , Sara Proietti , Alessandro Palombo et al.

Experimental Cell Research, 2016, 345 (1), pp.37-50. ⟨10.1016/j.yexcr.2016.05.007⟩

Article dans une revue (data paper) istex hal-05430179v1

39P Analysis of the immune response patterns in localized prostate cancer

S. Merler , B. Calì , S. Zumerle , D. Braga , V. Moscarda et al.

ESMO - Immuno-Oncology and Technology, Dec 2024, Geneve, Suisse, Switzerland. pp.100921, ⟨10.1016/j.iotech.2024.100921⟩

Communication dans un congrès hal-05430124v1

Deciphering the direct and indirect antitumoral effects of cold atmospheric plasma - application to the cholangiocarcinoma

Allan Pavy , Henri Decauchy , Bouchra Lekbaby , Manon Soulier , Mirko Minini et al.

International Workshop on Plasma Cancer (IWPCT 8), Mar 2023, Raleigh, United States

Communication dans un congrès hal-04397200v1

Unravelling the multifaceted antitumor effects of cold atmospheric pasma on cholangiocarcinoma

Allan Pavy , Henri Decauchy , Bouchra Lekbaby , Manon Soulier , Mirko Minini et al.

2nd annual meeting of COST PlasTher, Sep 2023, Bologna, Italy

Communication dans un congrès hal-04397245v1

Experimental Model of Biliary Tract Cancers: Subcutaneous Xenograft of Human Cell Lines in Immunodeficient Nude Mice

Bouchra Lekbaby , Javier Vaquero , Allan Pavy , Mirko Minini , Ester Gonzalez-Sanchez et al.

Liver Carcinogenesis, 2769, Springer US, pp.87-98, 2024, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3694-7_7⟩

Chapitre d'ouvrage hal-05430246v1

Revisiting the Concept of Human Disease

Mariano Bizzarri , Mirko Minini , Noemi Monti

Approaching Complex Diseases, 2, Springer International Publishing, pp.1-34, 2020, Human Perspectives in Health Sciences and Technology, ⟨10.1007/978-3-030-32857-3_1⟩

Chapitre d'ouvrage hal-05430248v1