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Bicyclic N,S-Acetals Containing Fused Cysteine-Amide System as New Heterocyclic Class Targeting Human Farnesyltransferase (FTase-h)
Fanny Danton
,
Mohamed Othman
,
Ata Martin Lawson
,
Amaury Farce
,
Emmanuelle Lipka
et al.
Article dans une revue
hal-05025962
v1
|
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Synthesis and Antiproliferative Effect of 3,4,5-Trimethoxylated Chalcones on Colorectal and Prostatic Cancer Cells
Cécile Letulle
,
François-Xavier Toublet
,
Aline Pinon
,
Soufyane Hba
,
Aurélie Laurent
et al.
Article dans une revue
hal-04699095
v1
|
|
Design and synthesis of novel N -benzyl-2,5-dihydro-1 H -pyrrole-linked benzopyrimidine conjugates as antimicrobial agents: study combining in vitro and in silico analysis
Sarra Chortani
,
Sami Ben Salah
,
Amel Hajlaoui
,
Mabrouk Horchani
,
Hayet Edziri
et al.
Article dans une revue
hal-04768002
v1
|
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Novel Oleanolic Acid-Phtalimidines Tethered 1,2, 3 Triazole Hy-Brids As Promising Antibacterial Agents: Design, Synthesis, In Vitro Experiments and In Silico Docking Studies
Ghofrane Lahmadi
,
Mabrouk Horchani
,
Anis Romdhane
,
Abdelkarim Mahdhi
,
Amal Dbeibia
et al.
Article dans une revue
hal-04767454
v1
|
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Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells
Yong Wang
,
Pascal Pigeon
,
Wei Li
,
Jiangkun Yan
,
Patrick M Dansette
et al.
Article dans une revue
hal-03599161
v1
|
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α-Hydroxylactams as Efficient Entries to Diversely Functionalized Ferrociphenols: Synthesis and Antiproliferative Activity Studies
Pascal Pigeon
,
Marie Gaschard
,
Mohamed Othman
,
Michèle Salmain
,
Gérard Jaouen
Article dans une revue
hal-03736842
v1
|
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Aza-heterocyclic frameworks through intramolecular π-system trapping of spiro-N-acyliminiums generated from isoindolinone
Sarra Chortani
,
Mohamed Othman
,
Ata Martin Lawson
,
Anis Romdhane
,
Hichem Ben Jannet
et al.
Article dans une revue
hal-03079155
v1
|
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Autotandem Catalysis: Inexpensive and Green Access to Functionalized Ketones by Intermolecular Iron‐Catalyzed Amidoalkynylation/Hydration Cascade Reaction via N ‐Acyliminium Ion Chemistry
Sidi Mohamed Abdallahi
,
Ewies Ewies
,
Mohamed El-Shazly
,
Brahim Ould Elemine
,
Abderrahmane Hadou
et al.
Article dans une revue
hal-04768506
v1
|
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Highly Enantioselective Semisynthesis of (+)/(−)-Gossypol Schiff Base Derivatives from Ground Plant Material
Mohamed Sidi Boune
,
Brahim Elemine
,
Ahmed Aliyenne
,
Abderrahmane Hadou
,
Adam Daïch
et al.
Article dans une revue
hal-02332614
v1
|
|
Indolylglycines Backbones in the Synthesis of Enantiopure 3,3-Spiroindolenines, Indolyl Tetracyclic Hemiaminals, and 3-Indolyl-maleimides Frameworks
Jozef Markus
,
Branislav Ferko
,
Dušan Berkeš
,
Ján Moncol
,
Ata Martin Lawson
et al.
Article dans une revue
hal-02332612
v1
|
|
Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species: a new family of potent farnesyltransferase inhibitors
Anthony Pesquet
,
Hamid Marzag
,
Michael Knorr
,
Carsten Strohmann
,
Ata Martin Lawson
et al.
Article dans une revue
hal-02332627
v1
|
|
Benzo[7,8]indolizinoquinoline scaffolds based on Mg(ClO4)2-promoted regiospecific imide reduction and π-cyclization of N-acyliminium species. Analogues of the topo-1 poison rosettacin and 22-hydroxyacuminatine alkaloids
Abdulkareem Hamid
,
Abdelaziz Souizi
,
Ata Martin Lawson
,
Mohamed Othman
,
Alina Ghinet
et al.
Article dans une revue
hal-02413296
v1
|
|
Phenyliodine(III) Diacetate/I 2 ‐Mediated Domino Approach for Pyrrolo[1,4]Thiazines and 1,4‐Thiazines by a One‐Pot Morin Rearrangement of N,S ‐ Acetals
Fanny Danton
,
Mohamed Othman
,
Ata Martin Lawson
,
Ján Moncol
,
Alina Ghinet
et al.
Article dans une revue
hal-02563783
v1
|
|
Design and semisynthesis of new herbicide as 1,2,3-triazole derivatives of the natural maslinic acid
Aymen Ben Nejma
,
Mansour Znati
,
Adam Daïch
,
Mohamed Othman
,
Ata Martin Lawson
et al.
Article dans une revue
hal-02332632
v1
|
|
Novel Hybrid Prins/Aza-Prins Oxocarbenium/N-Acyliminium Cascade Expedient Access to Complex Indolizidines
Mathéo Berthet
,
Alice Beauseigneur
,
Charlotte Moine
,
Catherine Taillier
,
Mohamed Othman
et al.
Article dans une revue
hal-02413309
v1
|
|
Structure-Based Kinetic Control in a Domino Process: A Powerful Tool Toward Molecular Diversity in Chromone Series
Thomas Lepitre
,
Clément Denhez
,
Jan Moncol
,
Mohamed Othman
,
Ata Martin Lawson
et al.
Article dans une revue
hal-02332616
v1
|
|
Development of SECheM Concept for Isolation and Chemical Modification of Gossypol Directly from Cienfuegosia digitata
Mohamed Vall Sidi Boune
,
Brahim Ould Elemine
,
Thomas Lepitre
,
Abderrahmane Ould Hadou
,
Ahmed Aliyenne
et al.
Article dans une revue
hal-02332630
v1
|
|
Phytochemical and biological studies of Atriplex inflata f. Muell.: isolation of secondary bioactive metabolites
Aymen Ben Nejma
,
Mansour Znati
,
Asma Nguir
,
Adam Daïch
,
Mohamed Othman
et al.
Article dans une revue
hal-02332617
v1
|
|
Metal-Free Cascade Approach toward Polysubstituted Indolizines from Chromone-Based Michael Acceptors
Thomas Lepitre
,
Raphael Le Biannic
,
Mohamed Othman
,
Ata Martin Lawson
,
Adam Daïch
Article dans une revue
hal-02332628
v1
|
|
Original Mitsunobu-Triggered Sequence Involved in a One-Pot Domino Process toward Tetracyclic Systems Bearing a Bis- N , O -acetal Junction
Thomas Lepitre
,
Clément Denhez
,
Morgane Sanselme
,
Mohamed Othman
,
Ata Martin Lawson
et al.
Article dans une revue
hal-01928655
v1
|
|
Use of chiral-pool approach into epi-thieno analogues of the scarce bioactive phenanthroquinolizidine alkaloids
Peter Šafář
,
Štefan Marchalín
,
Nadežda Prónayová
,
Viktor Vrábel
,
Ata Martin Lawson
et al.
Article dans une revue
hal-02413311
v1
|
|
New septanoside and 20-hydroxyecdysone septanoside derivative from Atriplex portulacoides roots with preliminary biological activities
Aymen Ben Nejma
,
Asma Nguir
,
Hichem Ben Jannet
,
M’hamed Ali Hamza
,
Adam Daïch
et al.
Article dans une revue
hal-02413288
v1
|
|
Sequential friedel-crafts-type α-amidoalkylation/intramolecular hydroarylation Distinct advantage of combined Tf2NH/cationic LAu(I) as a consecutive or binary bicatalytic system
Liliana Boiaryna
,
Mohamed Salah Azizi
,
Abderrahman El Bouakher
,
Baptiste Picard
,
Catherine Taillier
et al.
Article dans une revue
hal-02413298
v1
|
|
Combining α-amidoalkylation reactions of N-acyliminium ions with ring-closing metathesis: access to versatile novel isoindolones spirocyclic compounds
Anthony Pesquet
,
Mohamed Othman
Article dans une revue
hal-02462210
v1
|
|
Dual Hard/Soft Gold Catalysis: Intermolecular Friedel-Crafts-Type α-Amidoalkylation/Alkyne Hydroarylation Sequences by N -Acyliminium Ion Chemistry
Liliana Boiaryna
,
Mohamed Kamal El mkaddem
,
Catherine Taillier
,
Vincent Dalla
,
Mohamed Othman
Article dans une revue
istex
hal-02889812
v1
|
|
A Convenient Synthesis of Novel Spiroisoindole γ-Halobutyrolactones via Halocyclization of γ-Ethylenic Acids
Mohamed Othman
,
Mohamed M. Rammah
,
Kabula Ciamala
,
Michael Knorr
,
Carsten Strohmann
et al.
Article dans une revue
hal-02889563
v1
|
|
One-pot enyne metathesis/Diels–Alder reaction for the construction of highly functionalized novel polycyclic aza-compounds
Raja Othman
,
Mohamed Othman
,
Servane Coste
,
Bernard Decroix
Article dans une revue
istex
hal-01933003
v1
|
|
Silver-catalyzed spirolactonization: first synthesis of spiroisoindole-γ-methylene-γ-butyrolactones
Mohamed Othman
,
Kabula Ciamala
,
Carsten Strohmann
,
Mohamed Rammah
Article dans une revue
istex
hal-02889830
v1
|
|
Halolactonization of g-Acetylenic Acids: Synthesis of Novel Spiroisoindole Halobutyrolactones
Mohamed Othman
,
Mohamed M. Rammah
,
Moncef Msaddek
,
Mohamed B. Rammah
Article dans une revue
hal-02889561
v1
|
|
Towards Simplifying the Chemistry of N -Acyliminium Ions: A One-Pot Protocol for the Preparation of 5-Acetoxy Pyrrolidin-2-ones and 2-Acetoxy N -Alkoxycarbonyl Pyrrolidines from Imides
Fridrich Szemes Jr.
,
Anthony Fousse
,
Raja Ben Othman
,
Till Bousquet
,
Mohamed Othman
et al.
Article dans une revue
hal-02889851
v1
|
|
Eco-friendly N-acyliminium ion chemistry: solvent-free HNTf2 and TIPSOTf-catalyzed α-amidoalkylation of silicon-based π-nucleophiles
Marie-José Tranchant
,
Charlotte Moine
,
Raja Ben Othman
,
Till Bousquet
,
Mohamed Othman
et al.
Article dans une revue
istex
hal-02889850
v1
|
|
N -Trialkylsilyl Bistrifluoromethanesulfonimides (R 3 SiNTf 2 ) Are Powerful Catalysts for the Highly Efficient α-Amido Alkylation Reactions of Silicon-Based Nucleophiles
Raja Ben Othman
,
Till Bousquet
,
Mohamed Othman
,
Vincent Dalla
Article dans une revue
hal-02889852
v1
|
|
Toward Improving the Chemistry of N -Acyliminium Ions: Nucleophilic Substitution Reactions of Pyrrolidinone Derivatives with Trialkylsilyl Nucleophiles Catalyzed by Triisopropylsilyltrifluoromethane Sulfonate (TIPSOTf)
Raja Ben Othman
,
Till Bousquet
,
Anthony Fousse
,
Mohamed Othman
,
Vincent Dalla
Article dans une revue
hal-02889854
v1
|
|
Thieno[2′,3′:5,6]azepino[2,1- a ]isoindolones from hydroxylactam-alcohols via N -acyliminium ion olefin cyclization
Pascal Pigeon
,
Mohamed Othman
,
Bernard Decroix
Article dans une revue
hal-01230407
v1
|
|
Quinoxalines, benzodiazepines and benzodiazocines fused to pyrrole and isoindole via N-acyliminium ion aromatic cyclization
Mohamed Othman
,
Pascal Pigeon
,
Pierre Netchitaïlo
,
Abdel Daich
,
Bernard Decroix
Article dans une revue
hal-01230410
v1
|
|
Polycyclic systems: Synthesis of isoindolo[2,1-b]pyrrolo[1,2-d] [2,4]benzodiazocine and isoindolo[1,2-d]pyrrolo[1,2-a][1,5]benzodiazocine
Mohamed Othman
,
Pascal Pigeon
,
Bernard Decroix
Article dans une revue
hal-01230411
v1
|
|
Acyliminium ion-olefin cyclization leading to isoindolo [2,1-a]quinoline derivatives
Pascal Pigeon
,
Mohamed Othman
,
Pierre Netchitaïlo
,
Bernard Decroix
Article dans une revue
hal-01230412
v1
|
|
Synthesis of Pyrrolidinothieno-(or [1]Benzothieno)[3]azepinones from the Corresponding Azepinediones or N-(Thienyl or [1]Benzothienyl)-acetylprolinals
Bernard Decroix
,
Mohamed Othman
,
Pierre Netchitaïlo
Article dans une revue
hal-02889449
v1
|
|
Synthesis and reduction of thieno[2 `,3 `(3 `,2 ` or 3 `,4 `): 5,6]-azocino[2,1-a]isoindole-7,13-diones
Mohamed Othman
,
Pascal Pigeon
,
Bernard Decroix
Article dans une revue
istex
hal-01230418
v1
|
|
New fused lactones from indolizinediones via N-acyliminium ions
Mohamed Othman
,
Pascal Pigeon
,
Bernard Decroix
Article dans une revue
hal-01230415
v1
|
|
Selective access to N-aryl or N-alkyl derivatives of isoindolo[2,1-b][2,4]benzo(or thieno)diazepines
Pascal Pigeon
,
Mohamed Othman
,
Pierre Netchitaïlo
,
Bernard Decroix
Article dans une revue
hal-01230416
v1
|
|
Acyliminium ion cyclizations: Synthesis of thieno[2',3':3,4]pyrrolo[2,1-a]isoindolone and benzo[a]thieno[2,3(3,2 or 3,4)-g]indolizinones
Mohamed Othman
,
Pascal Pigeon
,
Bernard Decroix
Article dans une revue
hal-01230423
v1
|
|
Synthesis of thienothiazocinoisoindolediones and thienothiazinoisoindolones from mercaptothiophenes and chloromethylphthalimide
Pierre Netchitaïlo
,
Mohamed Othman
,
Bernard Decroix
Article dans une revue
istex
hal-02889444
v1
|
|
Intramolecular cyclization of amido acids into pyrrolidinothieno(or [1]benzothieno)[3]azepinediones
Mohamed Othman
,
Pierre Netchitaïlo
,
Bernard Decroix
Article dans une revue
istex
hal-02889442
v1
|
|
Synthesis of 5-chloropyrrole carboxaldehydes from 5-oxopyrrolidine carboxamides
Nicolas Hucher
,
Pierre Netchitaïlo
,
Mohamed Othman
,
Adam Daïch
,
Bernard Decroix
Article dans une revue
istex
hal-02564968
v1
|
|
Synthesis of Phthalimidine-3-carboxylate and Benzopyrroloindolizine from N-(Pyrrol-2-yl) Phthalimidine-3-Carboxylate
Mohamed Othman
,
Bernard Decroix
Article dans une revue
hal-02889440
v1
|